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Compile Data Set for Download or QSAR

Found 4 hits from Emory University CSI   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone acetyltransferase p300


(Homo sapiens (Human))
BDBM50395258
PNG
(CHEMBL2163602)
Show SMILES CC(C)CN(Cc1ccc2OC(C)(C)C=Cc2c1)S(=O)(=O)c1nccs1
Show InChI InChI=1S/C19H24N2O3S2/c1-14(2)12-21(26(22,23)18-20-9-10-25-18)13-15-5-6-17-16(11-15)7-8-19(3,4)24-17/h5-11,14H,12-13H2,1-4H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Emory University CSI

Curated by ChEMBL


Assay Description
Inhibition of P300 CH1 domain-mediated HIF1 transcriptional activity in human LN229-V6R cells assessed as reduction in luciferase activity incubated ...


J Med Chem 55: 6738-50 (2012)


Article DOI: 10.1021/jm300752n
BindingDB Entry DOI: 10.7270/Q24B32F3
More data for this
Ligand-Target Pair
Histone acetyltransferase p300


(Homo sapiens (Human))
BDBM50395261
PNG
(CHEMBL2163594)
Show SMILES CC(C)CN(Cc1ccc2OC(C)(C)C=Cc2c1)S(=O)(=O)c1ccccn1
Show InChI InChI=1S/C21H26N2O3S/c1-16(2)14-23(27(24,25)20-7-5-6-12-22-20)15-17-8-9-19-18(13-17)10-11-21(3,4)26-19/h5-13,16H,14-15H2,1-4H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Emory University CSI

Curated by ChEMBL


Assay Description
Inhibition of P300 CH1 domain-mediated HIF1 transcriptional activity in human LN229-V6R cells assessed as reduction in luciferase activity incubated ...


J Med Chem 55: 6738-50 (2012)


Article DOI: 10.1021/jm300752n
BindingDB Entry DOI: 10.7270/Q24B32F3
More data for this
Ligand-Target Pair
Histone acetyltransferase p300


(Homo sapiens (Human))
BDBM50395260
PNG
(CHEMBL2163598)
Show SMILES COc1cc(CN(C(C)C)S(=O)(=O)c2ccccn2)cc2C=CC(C)(C)Oc12
Show InChI InChI=1S/C21H26N2O4S/c1-15(2)23(28(24,25)19-8-6-7-11-22-19)14-16-12-17-9-10-21(3,4)27-20(17)18(13-16)26-5/h6-13,15H,14H2,1-5H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Emory University CSI

Curated by ChEMBL


Assay Description
Inhibition of P300 CH1 domain-mediated HIF1 transcriptional activity in human LN229-V6R cells assessed as reduction in luciferase activity incubated ...


J Med Chem 55: 6738-50 (2012)


Article DOI: 10.1021/jm300752n
BindingDB Entry DOI: 10.7270/Q24B32F3
More data for this
Ligand-Target Pair
Histone acetyltransferase p300


(Homo sapiens (Human))
BDBM50395259
PNG
(CHEMBL2163601)
Show SMILES CC(C)CN(Cc1ccc2OC(C)(C)C=Cc2c1)S(=O)(=O)c1nccn1C
Show InChI InChI=1S/C20H27N3O3S/c1-15(2)13-23(27(24,25)19-21-10-11-22(19)5)14-16-6-7-18-17(12-16)8-9-20(3,4)26-18/h6-12,15H,13-14H2,1-5H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Emory University CSI

Curated by ChEMBL


Assay Description
Inhibition of P300 CH1 domain-mediated HIF1 transcriptional activity in human LN229-V6R cells assessed as reduction in luciferase activity incubated ...


J Med Chem 55: 6738-50 (2012)


Article DOI: 10.1021/jm300752n
BindingDB Entry DOI: 10.7270/Q24B32F3
More data for this
Ligand-Target Pair