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Compile Data Set for Download or QSAR

Found 210 hits from deCODE   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50277407
PNG
(CHEMBL473288 | N-(4-bromophenyl)-4-(pyridin-4-ylme...)
Show SMILES Brc1ccc(NC(=O)c2nscc2NCc2ccncc2)cc1
Show InChI InChI=1S/C16H13BrN4OS/c17-12-1-3-13(4-2-12)20-16(22)15-14(10-23-21-15)19-9-11-5-7-18-8-6-11/h1-8,10,19H,9H2,(H,20,22)
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70n/an/an/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) at IC90 concentration by ATP based competition assay


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50248494
PNG
(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)
Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1
Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-4-3-5-17(12-16)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2
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80n/an/an/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Binding affinity to VEGFR2 (unknown origin) at IC90 in presence of ATP


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50248494
PNG
(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)
Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1
Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-4-3-5-17(12-16)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2
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90n/an/an/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Binding affinity to VEGFR2 (unknown origin) at IC50 in presence of ATP


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50277407
PNG
(CHEMBL473288 | N-(4-bromophenyl)-4-(pyridin-4-ylme...)
Show SMILES Brc1ccc(NC(=O)c2nscc2NCc2ccncc2)cc1
Show InChI InChI=1S/C16H13BrN4OS/c17-12-1-3-13(4-2-12)20-16(22)15-14(10-23-21-15)19-9-11-5-7-18-8-6-11/h1-8,10,19H,9H2,(H,20,22)
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90n/an/an/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) at IC50 concentration by ATP based competition assay


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50248491
PNG
(2-(1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)
Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1
Show InChI InChI=1S/C20H16ClN5/c21-16-4-3-5-17(12-16)26-14-20(24-25-26)18-6-1-2-7-19(18)23-13-15-8-10-22-11-9-15/h1-12,14,23H,13H2
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110n/an/an/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Binding affinity to VEGFR2 (unknown origin) at IC90 in presence of ATP


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50277363
PNG
(CHEMBL475510 | N-(3-tert-butylphenyl)-4-(pyridin-4...)
Show SMILES CC(C)(C)c1cccc(NC(=O)c2nscc2NCc2ccncc2)c1
Show InChI InChI=1S/C20H22N4OS/c1-20(2,3)15-5-4-6-16(11-15)23-19(25)18-17(13-26-24-18)22-12-14-7-9-21-10-8-14/h4-11,13,22H,12H2,1-3H3,(H,23,25)
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120n/an/an/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) at IC90 concentration by ATP based competition assay


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50248491
PNG
(2-(1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)
Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1
Show InChI InChI=1S/C20H16ClN5/c21-16-4-3-5-17(12-16)26-14-20(24-25-26)18-6-1-2-7-19(18)23-13-15-8-10-22-11-9-15/h1-12,14,23H,13H2
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120n/an/an/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Binding affinity to VEGFR2 (unknown origin) at IC50 in presence of ATP


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50277281
PNG
(4-(pyridin-4-ylmethylamino)-N-(3-(trifluoromethyl)...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2nscc2NCc2ccncc2)c1
Show InChI InChI=1S/C17H13F3N4OS/c18-17(19,20)12-2-1-3-13(8-12)23-16(25)15-14(10-26-24-15)22-9-11-4-6-21-7-5-11/h1-8,10,22H,9H2,(H,23,25)
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130n/an/an/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) at IC90 concentration by ATP based competition assay


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50277363
PNG
(CHEMBL475510 | N-(3-tert-butylphenyl)-4-(pyridin-4...)
Show SMILES CC(C)(C)c1cccc(NC(=O)c2nscc2NCc2ccncc2)c1
Show InChI InChI=1S/C20H22N4OS/c1-20(2,3)15-5-4-6-16(11-15)23-19(25)18-17(13-26-24-18)22-12-14-7-9-21-10-8-14/h4-11,13,22H,12H2,1-3H3,(H,23,25)
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130n/an/an/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) at IC50 concentration by ATP based competition assay


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50248584
PNG
(2-(1-(3-isopropylphenyl)-1H-1,2,3-triazol-4-yl)-N-...)
Show SMILES CC(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1
Show InChI InChI=1S/C23H23N5/c1-17(2)19-6-5-7-20(14-19)28-16-23(26-27-28)21-8-3-4-9-22(21)25-15-18-10-12-24-13-11-18/h3-14,16-17,25H,15H2,1-2H3
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140n/an/an/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Binding affinity to VEGFR2 (unknown origin) at IC90 in presence of ATP


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50248584
PNG
(2-(1-(3-isopropylphenyl)-1H-1,2,3-triazol-4-yl)-N-...)
Show SMILES CC(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1
Show InChI InChI=1S/C23H23N5/c1-17(2)19-6-5-7-20(14-19)28-16-23(26-27-28)21-8-3-4-9-22(21)25-15-18-10-12-24-13-11-18/h3-14,16-17,25H,15H2,1-2H3
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160n/an/an/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Binding affinity to VEGFR2 (unknown origin) at IC50 in presence of ATP


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50277281
PNG
(4-(pyridin-4-ylmethylamino)-N-(3-(trifluoromethyl)...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2nscc2NCc2ccncc2)c1
Show InChI InChI=1S/C17H13F3N4OS/c18-17(19,20)12-2-1-3-13(8-12)23-16(25)15-14(10-26-24-15)22-9-11-4-6-21-7-5-11/h1-8,10,22H,9H2,(H,23,25)
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160n/an/an/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) at IC50 concentration by ATP based competition assay


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM9503
PNG
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1
Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27)
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n/an/a 1.20n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA in presence of 8 uM ATP


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM9503
PNG
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1
Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27)
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n/an/a 1.20n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGF-induced VEGFR2 phosphorylation (unknown origin) expressed in CHO cells in presence of 8 uM ATP by ELISA


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM4851
PNG
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Show SMILES Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1
Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)
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n/an/a 16n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGF-induced VEGFR2 phosphorylation (unknown origin) expressed in CHO cells in presence of 8 uM ATP by ELISA


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM4851
PNG
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Show SMILES Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1
Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)
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n/an/a 16n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA in presence of 8 uM ATP


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM4851
PNG
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Show SMILES Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1
Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)
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n/an/a 21n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM4851
PNG
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Show SMILES Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1
Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)
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n/an/a 21n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) expressed in HEK293 cells assessed as inhibition of receptor phosphorylation by ELISA


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM9503
PNG
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1
Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27)
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n/an/a 23n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 8 uM ATP


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM9503
PNG
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1
Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27)
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n/an/a 23n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 8 uM ATP by HTRF assay


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50277406
PNG
(CHEMBL473287 | N-(3-bromophenyl)-4-(pyridin-4-ylme...)
Show SMILES Brc1cccc(NC(=O)c2nscc2NCc2ccncc2)c1
Show InChI InChI=1S/C16H13BrN4OS/c17-12-2-1-3-13(8-12)20-16(22)15-14(10-23-21-15)19-9-11-4-6-18-7-5-11/h1-8,10,19H,9H2,(H,20,22)
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n/an/a 27n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assay


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM9503
PNG
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1
Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27)
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n/an/a 32n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assay


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM9503
PNG
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1
Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27)
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n/an/a 32n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50277361
PNG
(4-(pyridin-4-ylmethylamino)-N-(3-(trifluoromethoxy...)
Show SMILES FC(F)(F)Oc1cccc(NC(=O)c2nscc2NCc2ccncc2)c1
Show InChI InChI=1S/C17H13F3N4O2S/c18-17(19,20)26-13-3-1-2-12(8-13)23-16(25)15-14(10-27-24-15)22-9-11-4-6-21-7-5-11/h1-8,10,22H,9H2,(H,23,25)
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n/an/a 33n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assay


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50277363
PNG
(CHEMBL475510 | N-(3-tert-butylphenyl)-4-(pyridin-4...)
Show SMILES CC(C)(C)c1cccc(NC(=O)c2nscc2NCc2ccncc2)c1
Show InChI InChI=1S/C20H22N4OS/c1-20(2,3)15-5-4-6-16(11-15)23-19(25)18-17(13-26-24-18)22-12-14-7-9-21-10-8-14/h4-11,13,22H,12H2,1-3H3,(H,23,25)
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n/an/a 35n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assay


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50277281
PNG
(4-(pyridin-4-ylmethylamino)-N-(3-(trifluoromethyl)...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2nscc2NCc2ccncc2)c1
Show InChI InChI=1S/C17H13F3N4OS/c18-17(19,20)12-2-1-3-13(8-12)23-16(25)15-14(10-26-24-15)22-9-11-4-6-21-7-5-11/h1-8,10,22H,9H2,(H,23,25)
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n/an/a 41n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assay


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50277361
PNG
(4-(pyridin-4-ylmethylamino)-N-(3-(trifluoromethoxy...)
Show SMILES FC(F)(F)Oc1cccc(NC(=O)c2nscc2NCc2ccncc2)c1
Show InChI InChI=1S/C17H13F3N4O2S/c18-17(19,20)26-13-3-1-2-12(8-13)23-16(25)15-14(10-27-24-15)22-9-11-4-6-21-7-5-11/h1-8,10,22H,9H2,(H,23,25)
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n/an/a 41n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) expressed in HEK293 cells assessed as inhibition of receptor phosphorylation by ELISA


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM4851
PNG
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Show SMILES Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1
Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)
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n/an/a 42n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 8 uM ATP by HTRF assay


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM4851
PNG
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Show SMILES Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1
Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)
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n/an/a 42n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 8 uM ATP


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50277436
PNG
(CHEMBL470441 | N-(4-methyl-3-(trifluoromethyl)phen...)
Show SMILES Cc1ccc(NC(=O)c2nscc2NCc2ccncc2)cc1C(F)(F)F
Show InChI InChI=1S/C18H15F3N4OS/c1-11-2-3-13(8-14(11)18(19,20)21)24-17(26)16-15(10-27-25-16)23-9-12-4-6-22-7-5-12/h2-8,10,23H,9H2,1H3,(H,24,26)
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n/an/a 43n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assay


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50248494
PNG
(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)
Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1
Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-4-3-5-17(12-16)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2
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n/an/a 51n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM4851
PNG
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Show SMILES Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1
Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)
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n/an/a 54n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50277281
PNG
(4-(pyridin-4-ylmethylamino)-N-(3-(trifluoromethyl)...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2nscc2NCc2ccncc2)c1
Show InChI InChI=1S/C17H13F3N4OS/c18-17(19,20)12-2-1-3-13(8-12)23-16(25)15-14(10-26-24-15)22-9-11-4-6-21-7-5-11/h1-8,10,22H,9H2,(H,23,25)
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n/an/a 54n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) expressed in HEK293 cells assessed as inhibition of receptor phosphorylation by ELISA


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM4851
PNG
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Show SMILES Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1
Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)
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n/an/a 54n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assay


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor


(Homo sapiens (human))
BDBM50277406
PNG
(CHEMBL473287 | N-(3-bromophenyl)-4-(pyridin-4-ylme...)
Show SMILES Brc1cccc(NC(=O)c2nscc2NCc2ccncc2)c1
Show InChI InChI=1S/C16H13BrN4OS/c17-12-2-1-3-13(8-12)20-16(22)15-14(10-23-21-15)19-9-11-4-6-18-7-5-11/h1-8,10,19H,9H2,(H,20,22)
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n/an/a 55n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR1 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assay


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50277436
PNG
(CHEMBL470441 | N-(4-methyl-3-(trifluoromethyl)phen...)
Show SMILES Cc1ccc(NC(=O)c2nscc2NCc2ccncc2)cc1C(F)(F)F
Show InChI InChI=1S/C18H15F3N4OS/c1-11-2-3-13(8-14(11)18(19,20)21)24-17(26)16-15(10-27-25-16)23-9-12-4-6-22-7-5-12/h2-8,10,23H,9H2,1H3,(H,24,26)
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n/an/a 56n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) expressed in HEK293 cells assessed as inhibition of receptor phosphorylation by ELISA


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50248537
PNG
(CHEMBL491502 | N-(pyridin-4-ylmethyl)-2-(1-(3-(tri...)
Show SMILES FC(F)(F)Oc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1
Show InChI InChI=1S/C21H16F3N5O/c22-21(23,24)30-17-5-3-4-16(12-17)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2
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n/an/a 66n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor


(Homo sapiens (human))
BDBM50248494
PNG
(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)
Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1
Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-4-3-5-17(12-16)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2
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n/an/a 66n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR1 (unknown origin) by HTRF assay


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor


(Homo sapiens (human))
BDBM50248537
PNG
(CHEMBL491502 | N-(pyridin-4-ylmethyl)-2-(1-(3-(tri...)
Show SMILES FC(F)(F)Oc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1
Show InChI InChI=1S/C21H16F3N5O/c22-21(23,24)30-17-5-3-4-16(12-17)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2
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n/an/a 72n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR1 (unknown origin) by HTRF assay


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50277363
PNG
(CHEMBL475510 | N-(3-tert-butylphenyl)-4-(pyridin-4...)
Show SMILES CC(C)(C)c1cccc(NC(=O)c2nscc2NCc2ccncc2)c1
Show InChI InChI=1S/C20H22N4OS/c1-20(2,3)15-5-4-6-16(11-15)23-19(25)18-17(13-26-24-18)22-12-14-7-9-21-10-8-14/h4-11,13,22H,12H2,1-3H3,(H,23,25)
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n/an/a 82n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) expressed in HEK293 cells assessed as inhibition of receptor phosphorylation by ELISA


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50248537
PNG
(CHEMBL491502 | N-(pyridin-4-ylmethyl)-2-(1-(3-(tri...)
Show SMILES FC(F)(F)Oc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1
Show InChI InChI=1S/C21H16F3N5O/c22-21(23,24)30-17-5-3-4-16(12-17)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2
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n/an/a 85n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50248491
PNG
(2-(1-(3-Chlorophenyl)-1H-1,2,3-triazol-4-yl)-N-(py...)
Show SMILES Clc1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1
Show InChI InChI=1S/C20H16ClN5/c21-16-4-3-5-17(12-16)26-14-20(24-25-26)18-6-1-2-7-19(18)23-13-15-8-10-22-11-9-15/h1-12,14,23H,13H2
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n/an/a 87n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM9503
PNG
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1
Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27)
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n/an/a 90n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM9503
PNG
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1
Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27)
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n/an/a 90n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) expressed in HEK293 cells assessed as inhibition of receptor phosphorylation by ELISA


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50248494
PNG
(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)
Show SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1
Show InChI InChI=1S/C21H16F3N5/c22-21(23,24)16-4-3-5-17(12-16)29-14-20(27-28-29)18-6-1-2-7-19(18)26-13-15-8-10-25-11-9-15/h1-12,14,26H,13H2
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n/an/a 96n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISA


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50277064
PNG
(4-(quinolin-4-ylmethylamino)-N-(3-(trifluoromethyl...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2nscc2NCc2ccnc3ccccc23)c1
Show InChI InChI=1S/C21H15F3N4OS/c22-21(23,24)14-4-3-5-15(10-14)27-20(29)19-18(12-30-28-19)26-11-13-8-9-25-17-7-2-1-6-16(13)17/h1-10,12,26H,11H2,(H,27,29)
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n/an/a 110n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assay


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor


(Homo sapiens (human))
BDBM4851
PNG
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Show SMILES Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1
Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)
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n/an/a 110n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR1 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 8 uM ATP by HTRF assay


Bioorg Med Chem Lett 19: 1195-8 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.078
BindingDB Entry DOI: 10.7270/Q2W66KNK
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor


(Homo sapiens (human))
BDBM50247946
PNG
(2-(1-(4-methyl-3-(trifluoromethyl)phenyl)-1H-1,2,3...)
Show SMILES Cc1ccc(cc1C(F)(F)F)-n1cc(nn1)-c1ccccc1NCc1ccncc1
Show InChI InChI=1S/C22H18F3N5/c1-15-6-7-17(12-19(15)22(23,24)25)30-14-21(28-29-30)18-4-2-3-5-20(18)27-13-16-8-10-26-11-9-16/h2-12,14,27H,13H2,1H3
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n/an/a 110n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR1 (unknown origin) by HTRF assay


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50248584
PNG
(2-(1-(3-isopropylphenyl)-1H-1,2,3-triazol-4-yl)-N-...)
Show SMILES CC(C)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1
Show InChI InChI=1S/C23H23N5/c1-17(2)19-6-5-7-20(14-19)28-16-23(26-27-28)21-8-3-4-9-22(21)25-15-18-10-12-24-13-11-18/h3-14,16-17,25H,15H2,1-2H3
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n/an/a 110n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATP


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor


(Homo sapiens (human))
BDBM4851
PNG
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Show SMILES Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1
Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)
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n/an/a 110n/an/an/an/an/an/a



deCODE

Curated by ChEMBL


Assay Description
Inhibition of VEGFR1 (unknown origin) by HTRF assay in presence of 8 uM ATP


Bioorg Med Chem Lett 19: 1344-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.046
BindingDB Entry DOI: 10.7270/Q2DV1JRT
More data for this
Ligand-Target Pair
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