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Compile Data Set for Download or QSAR

Found 68 hits with Last Name = 'abate' and Initial = 'a'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141381
PNG
(CHEMBL3758184)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CCCN(CCc4ccccc4)C3)CC(=O)c2c1
Show InChI InChI=1S/C24H26N2O4/c27-21-16-24(12-4-13-26(17-24)14-11-18-5-2-1-3-6-18)30-22-9-7-19(15-20(21)22)8-10-23(28)25-29/h1-3,5-10,15,29H,4,11-14,16-17H2,(H,25,28)/b10-8+
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n/an/a 1n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase 3/NCoR1


(Homo sapiens (human))
BDBM50361444
PNG
(CHEMBL1938433)
Show SMILES ONC(=O)C=Cc1ccc2OC3(CCN(Cc4ccccc4)CC3)CC(=O)c2c1
Show InChI InChI=1S/C23H24N2O4/c26-20-15-23(10-12-25(13-11-23)16-18-4-2-1-3-5-18)29-21-8-6-17(14-19(20)21)7-9-22(27)24-28/h1-9,14,28H,10-13,15-16H2,(H,24,27)
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n/an/a 9.40n/an/an/an/an/an/a



DAC SRL

Curated by ChEMBL


Assay Description
Inhibition of HDAC3 using carboxyfluorescein-labeled peptide as substrate after 17 hrs by fluorescence assay


J Med Chem 54: 3051-64 (2011)


Article DOI: 10.1021/jm200146u
BindingDB Entry DOI: 10.7270/Q21V5FD6
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM50361444
PNG
(CHEMBL1938433)
Show SMILES ONC(=O)C=Cc1ccc2OC3(CCN(Cc4ccccc4)CC3)CC(=O)c2c1
Show InChI InChI=1S/C23H24N2O4/c26-20-15-23(10-12-25(13-11-23)16-18-4-2-1-3-5-18)29-21-8-6-17(14-19(20)21)7-9-22(27)24-28/h1-9,14,28H,10-13,15-16H2,(H,24,27)
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n/an/a 25.7n/an/an/an/an/an/a



DAC SRL

Curated by ChEMBL


Assay Description
Inhibition of HDAC6 using carboxyfluorescein-labeled peptide as substrate after 17 hrs by fluorescence assay


J Med Chem 54: 3051-64 (2011)


Article DOI: 10.1021/jm200146u
BindingDB Entry DOI: 10.7270/Q21V5FD6
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141111
PNG
(CHEMBL3758901)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CCN(Cc4ccccc4)C3)CC(=O)c2c1
Show InChI InChI=1S/C22H22N2O4/c25-19-13-22(10-11-24(15-22)14-17-4-2-1-3-5-17)28-20-8-6-16(12-18(19)20)7-9-21(26)23-27/h1-9,12,27H,10-11,13-15H2,(H,23,26)/b9-7+
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n/an/a 26n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141185
PNG
(CHEMBL3759550)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CCN(CCc4ccccc4)C3)CC(=O)c2c1
Show InChI InChI=1S/C23H24N2O4/c26-20-15-23(11-13-25(16-23)12-10-17-4-2-1-3-5-17)29-21-8-6-18(14-19(20)21)7-9-22(27)24-28/h1-9,14,28H,10-13,15-16H2,(H,24,27)/b9-7+
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n/an/a 27n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase 3/NCoR1


(Homo sapiens (human))
BDBM50141111
PNG
(CHEMBL3758901)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CCN(Cc4ccccc4)C3)CC(=O)c2c1
Show InChI InChI=1S/C22H22N2O4/c25-19-13-22(10-11-24(15-22)14-17-4-2-1-3-5-17)28-20-8-6-16(12-18(19)20)7-9-21(26)23-27/h1-9,12,27H,10-11,13-15H2,(H,23,26)/b9-7+
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n/an/a 28n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC3 (unknown origin)


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM19149
PNG
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1
Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
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n/an/a 29n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC6 (unknown origin)


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase 3/NCoR1


(Homo sapiens (human))
BDBM50141139
PNG
(CHEMBL3759808)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CC(=O)c2c1)CCCN(Cc1ccccc1)CC3
Show InChI InChI=1S/C24H26N2O4/c27-21-16-24(11-4-13-26(14-12-24)17-19-5-2-1-3-6-19)30-22-9-7-18(15-20(21)22)8-10-23(28)25-29/h1-3,5-10,15,29H,4,11-14,16-17H2,(H,25,28)/b10-8+
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n/an/a 30n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC3 (unknown origin)


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141361
PNG
(CHEMBL3758716)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CCCN(Cc4ccc(F)cc4)C3)CC(=O)c2c1
Show InChI InChI=1S/C23H23FN2O4/c24-18-6-2-17(3-7-18)14-26-11-1-10-23(15-26)13-20(27)19-12-16(4-8-21(19)30-23)5-9-22(28)25-29/h2-9,12,29H,1,10-11,13-15H2,(H,25,28)/b9-5+
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n/an/a 34n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141111
PNG
(CHEMBL3758901)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CCN(Cc4ccccc4)C3)CC(=O)c2c1
Show InChI InChI=1S/C22H22N2O4/c25-19-13-22(10-11-24(15-22)14-17-4-2-1-3-5-17)28-20-8-6-16(12-18(19)20)7-9-21(26)23-27/h1-9,12,27H,10-11,13-15H2,(H,23,26)/b9-7+
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n/an/a 37n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141111
PNG
(CHEMBL3758901)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CCN(Cc4ccccc4)C3)CC(=O)c2c1
Show InChI InChI=1S/C22H22N2O4/c25-19-13-22(10-11-24(15-22)14-17-4-2-1-3-5-17)28-20-8-6-16(12-18(19)20)7-9-21(26)23-27/h1-9,12,27H,10-11,13-15H2,(H,23,26)/b9-7+
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n/an/a 52n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase 3/NCoR1


(Homo sapiens (human))
BDBM19149
PNG
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1
Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
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n/an/a 55n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC3 (unknown origin)


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase 3/NCoR1


(Homo sapiens (human))
BDBM19149
PNG
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1
Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
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n/an/a 55n/an/an/an/an/an/a



Congenia s.r.l.

Curated by ChEMBL


Assay Description
Inhibition of HDAC3 (unknown origin)


Eur J Med Chem 64: 273-84 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.061
BindingDB Entry DOI: 10.7270/Q2TT4SBV
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141608
PNG
(CHEMBL3758515)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CC(=O)c2c1)CCCN(CCc1ccccc1)CC3
Show InChI InChI=1S/C25H28N2O4/c28-22-18-25(31-23-9-7-20(17-21(22)23)8-10-24(29)26-30)12-4-14-27(16-13-25)15-11-19-5-2-1-3-6-19/h1-3,5-10,17,30H,4,11-16,18H2,(H,26,29)/b10-8+
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n/an/a 56n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141241
PNG
(CHEMBL3758450)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CCCN(Cc4ccccc4)C3)CC(=O)c2c1
Show InChI InChI=1S/C23H24N2O4/c26-20-14-23(11-4-12-25(16-23)15-18-5-2-1-3-6-18)29-21-9-7-17(13-19(20)21)8-10-22(27)24-28/h1-3,5-10,13,28H,4,11-12,14-16H2,(H,24,27)/b10-8+
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n/an/a 56n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141176
PNG
(CHEMBL3760098)
Show SMILES Cn1cc(CN2CC3(C2)CC(=O)c2cc(\C=C\C(=O)NO)ccc2O3)c2ccccc12
Show InChI InChI=1S/C24H23N3O4/c1-26-12-17(18-4-2-3-5-20(18)26)13-27-14-24(15-27)11-21(28)19-10-16(6-8-22(19)31-24)7-9-23(29)25-30/h2-10,12,30H,11,13-15H2,1H3,(H,25,29)/b9-7+
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n/an/a 62n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase 3/NCoR1


(Homo sapiens (human))
BDBM50361444
PNG
(CHEMBL1938433)
Show SMILES ONC(=O)C=Cc1ccc2OC3(CCN(Cc4ccccc4)CC3)CC(=O)c2c1
Show InChI InChI=1S/C23H24N2O4/c26-20-15-23(10-12-25(13-11-23)16-18-4-2-1-3-5-18)29-21-8-6-17(14-19(20)21)7-9-22(27)24-28/h1-9,14,28H,10-13,15-16H2,(H,24,27)
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n/an/a 65n/an/an/an/an/an/a



Congenia s.r.l.

Curated by ChEMBL


Assay Description
Inhibition of HDAC3 (unknown origin)


Eur J Med Chem 64: 273-84 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.061
BindingDB Entry DOI: 10.7270/Q2TT4SBV
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141144
PNG
(CHEMBL3759197)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CN(Cc4ccccc4)C3)CC(=O)c2c1
Show InChI InChI=1S/C21H20N2O4/c24-18-11-21(13-23(14-21)12-16-4-2-1-3-5-16)27-19-8-6-15(10-17(18)19)7-9-20(25)22-26/h1-10,26H,11-14H2,(H,22,25)/b9-7+
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n/an/a 67n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM50141139
PNG
(CHEMBL3759808)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CC(=O)c2c1)CCCN(Cc1ccccc1)CC3
Show InChI InChI=1S/C24H26N2O4/c27-21-16-24(11-4-13-26(14-12-24)17-19-5-2-1-3-6-19)30-22-9-7-18(15-20(21)22)8-10-23(28)25-29/h1-3,5-10,15,29H,4,11-14,16-17H2,(H,25,28)/b10-8+
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n/an/a 72n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC2 (unknown origin)


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141139
PNG
(CHEMBL3759808)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CC(=O)c2c1)CCCN(Cc1ccccc1)CC3
Show InChI InChI=1S/C24H26N2O4/c27-21-16-24(11-4-13-26(14-12-24)17-19-5-2-1-3-6-19)30-22-9-7-18(15-20(21)22)8-10-23(28)25-29/h1-3,5-10,15,29H,4,11-14,16-17H2,(H,25,28)/b10-8+
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n/an/a 73n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141178
PNG
(CHEMBL3759521)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CN(C3)C(=O)c3ccccc3)CC(=O)c2c1
Show InChI InChI=1S/C21H18N2O5/c24-17-11-21(12-23(13-21)20(26)15-4-2-1-3-5-15)28-18-8-6-14(10-16(17)18)7-9-19(25)22-27/h1-10,27H,11-13H2,(H,22,25)/b9-7+
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n/an/a 81n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM50141111
PNG
(CHEMBL3758901)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CCN(Cc4ccccc4)C3)CC(=O)c2c1
Show InChI InChI=1S/C22H22N2O4/c25-19-13-22(10-11-24(15-22)14-17-4-2-1-3-5-17)28-20-8-6-16(12-18(19)20)7-9-21(26)23-27/h1-9,12,27H,10-11,13-15H2,(H,23,26)/b9-7+
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n/an/a 82n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC2 (unknown origin)


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141241
PNG
(CHEMBL3758450)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CCCN(Cc4ccccc4)C3)CC(=O)c2c1
Show InChI InChI=1S/C23H24N2O4/c26-20-14-23(11-4-12-25(16-23)15-18-5-2-1-3-6-18)29-21-9-7-17(13-19(20)21)8-10-22(27)24-28/h1-3,5-10,13,28H,4,11-12,14-16H2,(H,24,27)/b10-8+
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n/an/a 84n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141184
PNG
(CHEMBL3759353)
Show SMILES Cn1cc(CN2CCC3(C2)CC(=O)c2cc(\C=C\C(=O)NO)ccc2O3)c2ccccc12
Show InChI InChI=1S/C25H25N3O4/c1-27-14-18(19-4-2-3-5-21(19)27)15-28-11-10-25(16-28)13-22(29)20-12-17(6-8-23(20)32-25)7-9-24(30)26-31/h2-9,12,14,31H,10-11,13,15-16H2,1H3,(H,26,30)/b9-7+
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n/an/a 85n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase 3/NCoR1


(Homo sapiens (human))
BDBM50435605
PNG
(CHEMBL2390999)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CCN(Cc4ccccc4)CC3)NC(=O)c2c1
Show InChI InChI=1S/C22H23N3O4/c26-20(24-28)9-7-16-6-8-19-18(14-16)21(27)23-22(29-19)10-12-25(13-11-22)15-17-4-2-1-3-5-17/h1-9,14,28H,10-13,15H2,(H,23,27)(H,24,26)/b9-7+
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n/an/a 87n/an/an/an/an/an/a



Congenia s.r.l.

Curated by ChEMBL


Assay Description
Inhibition of HDAC3 (unknown origin)


Eur J Med Chem 64: 273-84 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.061
BindingDB Entry DOI: 10.7270/Q2TT4SBV
More data for this
Ligand-Target Pair
Histone deacetylase 3/NCoR1


(Homo sapiens (human))
BDBM50435604
PNG
(CHEMBL2390995)
Show SMILES ONC(=O)C=Cc1ccc2OC3(CCN(Cc4ccc(F)cc4)CC3)CC(=O)c2c1
Show InChI InChI=1S/C23H23FN2O4/c24-18-5-1-17(2-6-18)15-26-11-9-23(10-12-26)14-20(27)19-13-16(3-7-21(19)30-23)4-8-22(28)25-29/h1-8,13,29H,9-12,14-15H2,(H,25,28)
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n/an/a 90n/an/an/an/an/an/a



Congenia s.r.l.

Curated by ChEMBL


Assay Description
Inhibition of HDAC3 (unknown origin)


Eur J Med Chem 64: 273-84 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.061
BindingDB Entry DOI: 10.7270/Q2TT4SBV
More data for this
Ligand-Target Pair
Histone deacetylase 3/NCoR1


(Homo sapiens (human))
BDBM50435604
PNG
(CHEMBL2390995)
Show SMILES ONC(=O)C=Cc1ccc2OC3(CCN(Cc4ccc(F)cc4)CC3)CC(=O)c2c1
Show InChI InChI=1S/C23H23FN2O4/c24-18-5-1-17(2-6-18)15-26-11-9-23(10-12-26)14-20(27)19-13-16(3-7-21(19)30-23)4-8-22(28)25-29/h1-8,13,29H,9-12,14-15H2,(H,25,28)
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n/an/a 92n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human HDAC3 after 15 mins by fluorescence assay


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (human))
BDBM50361444
PNG
(CHEMBL1938433)
Show SMILES ONC(=O)C=Cc1ccc2OC3(CCN(Cc4ccccc4)CC3)CC(=O)c2c1
Show InChI InChI=1S/C23H24N2O4/c26-20-15-23(10-12-25(13-11-23)16-18-4-2-1-3-5-18)29-21-8-6-17(14-19(20)21)7-9-22(27)24-28/h1-9,14,28H,10-13,15-16H2,(H,24,27)
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n/an/a 93.8n/an/an/an/an/an/a



DAC SRL

Curated by ChEMBL


Assay Description
Inhibition of HDAC1 using carboxyfluorescein-labeled peptide as substrate after 17 hrs by fluorescence assay


J Med Chem 54: 3051-64 (2011)


Article DOI: 10.1021/jm200146u
BindingDB Entry DOI: 10.7270/Q21V5FD6
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM19149
PNG
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1
Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
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n/an/a 102n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50435604
PNG
(CHEMBL2390995)
Show SMILES ONC(=O)C=Cc1ccc2OC3(CCN(Cc4ccc(F)cc4)CC3)CC(=O)c2c1
Show InChI InChI=1S/C23H23FN2O4/c24-18-5-1-17(2-6-18)15-26-11-9-23(10-12-26)14-20(27)19-13-16(3-7-21(19)30-23)4-8-22(28)25-29/h1-8,13,29H,9-12,14-15H2,(H,25,28)
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n/an/a 108n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141609
PNG
(CHEMBL3758233)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CC(=O)c2c1)CCCN(CC3)C(=O)c1ccccc1
Show InChI InChI=1S/C24H24N2O5/c27-20-16-24(31-21-9-7-17(15-19(20)21)8-10-22(28)25-30)11-4-13-26(14-12-24)23(29)18-5-2-1-3-6-18/h1-3,5-10,15,30H,4,11-14,16H2,(H,25,28)/b10-8+
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n/an/a 110n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50435606
PNG
(CHEMBL2390996)
Show SMILES ONC(=O)C=Cc1ccc2OC3(CCN(CCc4ccccc4)CC3)CC(=O)c2c1
Show InChI InChI=1S/C24H26N2O4/c27-21-17-24(11-14-26(15-12-24)13-10-18-4-2-1-3-5-18)30-22-8-6-19(16-20(21)22)7-9-23(28)25-29/h1-9,16,29H,10-15,17H2,(H,25,28)
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n/an/a 113n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141386
PNG
(CHEMBL3759339)
Show SMILES CN1CCCC2(CC(=O)c3cc(\C=C\C(=O)NO)ccc3O2)CC1
Show InChI InChI=1S/C18H22N2O4/c1-20-9-2-7-18(8-10-20)12-15(21)14-11-13(3-5-16(14)24-18)4-6-17(22)19-23/h3-6,11,23H,2,7-10,12H2,1H3,(H,19,22)/b6-4+
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n/an/a 114n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141607
PNG
(CHEMBL3758352)
Show SMILES Cn1cc(CN2CCCC3(CC(=O)c4cc(\C=C\C(=O)NO)ccc4O3)CC2)c2ccccc12
Show InChI InChI=1S/C27H29N3O4/c1-29-17-20(21-5-2-3-6-23(21)29)18-30-13-4-11-27(12-14-30)16-24(31)22-15-19(7-9-25(22)34-27)8-10-26(32)28-33/h2-3,5-10,15,17,33H,4,11-14,16,18H2,1H3,(H,28,32)/b10-8+
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n/an/a 114n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141180
PNG
(CHEMBL3759365)
Show SMILES CN1CCC2(C1)CC(=O)c1cc(\C=C\C(=O)NO)ccc1O2
Show InChI InChI=1S/C16H18N2O4/c1-18-7-6-16(10-18)9-13(19)12-8-11(2-4-14(12)22-16)3-5-15(20)17-21/h2-5,8,21H,6-7,9-10H2,1H3,(H,17,20)/b5-3+
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n/an/a 119n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM50141111
PNG
(CHEMBL3758901)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CCN(Cc4ccccc4)C3)CC(=O)c2c1
Show InChI InChI=1S/C22H22N2O4/c25-19-13-22(10-11-24(15-22)14-17-4-2-1-3-5-17)28-20-8-6-16(12-18(19)20)7-9-21(26)23-27/h1-9,12,27H,10-11,13-15H2,(H,23,26)/b9-7+
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n/an/a 123n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC6 (unknown origin)


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase 4


(Homo sapiens (Human))
BDBM50361444
PNG
(CHEMBL1938433)
Show SMILES ONC(=O)C=Cc1ccc2OC3(CCN(Cc4ccccc4)CC3)CC(=O)c2c1
Show InChI InChI=1S/C23H24N2O4/c26-20-15-23(10-12-25(13-11-23)16-18-4-2-1-3-5-18)29-21-8-6-17(14-19(20)21)7-9-22(27)24-28/h1-9,14,28H,10-13,15-16H2,(H,24,27)
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n/an/a 127n/an/an/an/an/an/a



DAC SRL

Curated by ChEMBL


Assay Description
Inhibition of HDAC4 using carboxyfluorescein-labeled peptide as substrate after 17 hrs by fluorescence assay


J Med Chem 54: 3051-64 (2011)


Article DOI: 10.1021/jm200146u
BindingDB Entry DOI: 10.7270/Q21V5FD6
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141175
PNG
(CHEMBL3758910)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CN(Cc4ccc(F)cc4)C3)CC(=O)c2c1
Show InChI InChI=1S/C21H19FN2O4/c22-16-5-1-15(2-6-16)11-24-12-21(13-24)10-18(25)17-9-14(3-7-19(17)28-21)4-8-20(26)23-27/h1-9,27H,10-13H2,(H,23,26)/b8-4+
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n/an/a 130n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase 3/NCoR1


(Homo sapiens (human))
BDBM50435606
PNG
(CHEMBL2390996)
Show SMILES ONC(=O)C=Cc1ccc2OC3(CCN(CCc4ccccc4)CC3)CC(=O)c2c1
Show InChI InChI=1S/C24H26N2O4/c27-21-17-24(11-14-26(15-12-24)13-10-18-4-2-1-3-5-18)30-22-8-6-19(16-20(21)22)7-9-23(28)25-29/h1-9,16,29H,10-15,17H2,(H,25,28)
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n/an/a 130n/an/an/an/an/an/a



Congenia s.r.l.

Curated by ChEMBL


Assay Description
Inhibition of HDAC3 (unknown origin)


Eur J Med Chem 64: 273-84 (2013)


Article DOI: 10.1016/j.ejmech.2013.03.061
BindingDB Entry DOI: 10.7270/Q2TT4SBV
More data for this
Ligand-Target Pair
Histone deacetylase 3/NCoR1


(Homo sapiens (human))
BDBM50435606
PNG
(CHEMBL2390996)
Show SMILES ONC(=O)C=Cc1ccc2OC3(CCN(CCc4ccccc4)CC3)CC(=O)c2c1
Show InChI InChI=1S/C24H26N2O4/c27-21-17-24(11-14-26(15-12-24)13-10-18-4-2-1-3-5-18)30-22-8-6-19(16-20(21)22)7-9-23(28)25-29/h1-9,16,29H,10-15,17H2,(H,25,28)
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n/an/a 130n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human HDAC3 after 15 mins by fluorescence assay


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141179
PNG
(CHEMBL3759091)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CCNC3)CC(=O)c2c1
Show InChI InChI=1S/C15H16N2O4/c18-12-8-15(5-6-16-9-15)21-13-3-1-10(7-11(12)13)2-4-14(19)17-20/h1-4,7,16,20H,5-6,8-9H2,(H,17,19)/b4-2+
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n/an/a 131n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141384
PNG
(CHEMBL3759976)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CC(=O)c2c1)CCCNCC3
Show InChI InChI=1S/C17H20N2O4/c20-14-11-17(6-1-8-18-9-7-17)23-15-4-2-12(10-13(14)15)3-5-16(21)19-22/h2-5,10,18,22H,1,6-9,11H2,(H,19,21)/b5-3+
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n/an/a 134n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141223
PNG
(CHEMBL3759169)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CCCNC3)CC(=O)c2c1
Show InChI InChI=1S/C16H18N2O4/c19-13-9-16(6-1-7-17-10-16)22-14-4-2-11(8-12(13)14)3-5-15(20)18-21/h2-5,8,17,21H,1,6-7,9-10H2,(H,18,20)/b5-3+
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n/an/a 136n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM50435606
PNG
(CHEMBL2390996)
Show SMILES ONC(=O)C=Cc1ccc2OC3(CCN(CCc4ccccc4)CC3)CC(=O)c2c1
Show InChI InChI=1S/C24H26N2O4/c27-21-17-24(11-14-26(15-12-24)13-10-18-4-2-1-3-5-18)30-22-8-6-19(16-20(21)22)7-9-23(28)25-29/h1-9,16,29H,10-15,17H2,(H,25,28)
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n/an/a 138n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human HDAC6 after 15 mins by fluorescence assay


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141241
PNG
(CHEMBL3758450)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CCCN(Cc4ccccc4)C3)CC(=O)c2c1
Show InChI InChI=1S/C23H24N2O4/c26-20-14-23(11-4-12-25(16-23)15-18-5-2-1-3-6-18)29-21-9-7-17(13-19(20)21)8-10-22(27)24-28/h1-3,5-10,13,28H,4,11-12,14-16H2,(H,24,27)/b10-8+
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n/an/a 143n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141606
PNG
(CHEMBL3759858)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CC(=O)c2c1)CCCN(Cc1ccc(F)cc1)CC3
Show InChI InChI=1S/C24H25FN2O4/c25-19-6-2-18(3-7-19)16-27-12-1-10-24(11-13-27)15-21(28)20-14-17(4-8-22(20)31-24)5-9-23(29)26-30/h2-9,14,30H,1,10-13,15-16H2,(H,26,29)/b9-5+
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n/an/a 149n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141182
PNG
(CHEMBL3758904)
Show SMILES CCOC(=O)N1CCC2(C1)CC(=O)c1cc(\C=C\C(=O)NO)ccc1O2
Show InChI InChI=1S/C18H20N2O6/c1-2-25-17(23)20-8-7-18(11-20)10-14(21)13-9-12(3-5-15(13)26-18)4-6-16(22)19-24/h3-6,9,24H,2,7-8,10-11H2,1H3,(H,19,22)/b6-4+
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n/an/a 150n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM50141139
PNG
(CHEMBL3759808)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CC(=O)c2c1)CCCN(Cc1ccccc1)CC3
Show InChI InChI=1S/C24H26N2O4/c27-21-16-24(11-4-13-26(14-12-24)17-19-5-2-1-3-6-19)30-22-9-7-18(15-20(21)22)8-10-23(28)25-29/h1-3,5-10,15,29H,4,11-14,16-17H2,(H,25,28)/b10-8+
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n/an/a 151n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC6 (unknown origin)


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141383
PNG
(CHEMBL3758604)
Show SMILES ONC(=O)\C=C\c1ccc2OC3(CCCN(C3)C(=O)c3ccccc3)CC(=O)c2c1
Show InChI InChI=1S/C23H22N2O5/c26-19-14-23(11-4-12-25(15-23)22(28)17-5-2-1-3-6-17)30-20-9-7-16(13-18(19)20)8-10-21(27)24-29/h1-3,5-10,13,29H,4,11-12,14-15H2,(H,24,27)/b10-8+
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n/an/a 165n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human)-Homo sapiens (Human))
BDBM50141141
PNG
(CHEMBL3758204)
Show SMILES CN1CC2(C1)CC(=O)c1cc(\C=C\C(=O)NO)ccc1O2
Show InChI InChI=1S/C15H16N2O4/c1-17-8-15(9-17)7-12(18)11-6-10(2-4-13(11)21-15)3-5-14(19)16-20/h2-6,20H,7-9H2,1H3,(H,16,19)/b5-3+
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n/an/a 168n/an/an/an/an/an/a



European Institute of Oncology

Curated by ChEMBL


Assay Description
Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysis


Eur J Med Chem 108: 53-67 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.010
BindingDB Entry DOI: 10.7270/Q2N87CN0
More data for this
Ligand-Target Pair
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