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Compile Data Set for Download or QSAR

Found 24 hits with Last Name = 'abdelhamid' and Initial = 'h'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088549
PNG
(CHEMBL3577026)
Show SMILES CS(=O)(=O)N1CCN(c2ccc(cc2)C(F)(F)F)c2ccc(cc2C1)-c1cccc(n1)[C@H](O)CO
Show InChI InChI=1S/C24H24F3N3O4S/c1-35(33,34)29-11-12-30(19-8-6-18(7-9-19)24(25,26)27)22-10-5-16(13-17(22)14-29)20-3-2-4-21(28-20)23(32)15-31/h2-10,13,23,31-32H,11-12,14-15H2,1H3/t23-/m1/s1
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230n/an/an/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) by electrophysiological assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088545
PNG
(CHEMBL3577022)
Show SMILES CC(=O)N1CCN(c2ccc(cc2)C(F)(F)F)c2ccc(cc2C1)-c1cccc(n1)C(N)=O
Show InChI InChI=1S/C24H21F3N4O2/c1-15(32)30-11-12-31(19-8-6-18(7-9-19)24(25,26)27)22-10-5-16(13-17(22)14-30)20-3-2-4-21(29-20)23(28)33/h2-10,13H,11-12,14H2,1H3,(H2,28,33)
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300n/an/an/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) by electrophysiological assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088546
PNG
(CHEMBL3577023)
Show SMILES NC(=O)CN1CCN(c2ccc(cc2)C(F)(F)F)c2ccc(cc2C1)-c1cccc(n1)[C@H](O)CO
Show InChI InChI=1S/C25H25F3N4O3/c26-25(27,28)18-5-7-19(8-6-18)32-11-10-31(14-24(29)35)13-17-12-16(4-9-22(17)32)20-2-1-3-21(30-20)23(34)15-33/h1-9,12,23,33-34H,10-11,13-15H2,(H2,29,35)/t23-/m1/s1
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300n/an/an/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) by electrophysiological assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088544
PNG
(CHEMBL3577021)
Show SMILES CN1CCN(c2ccc(cc2)C(F)(F)F)c2ccc(cc2C1)-c1cccc(n1)C(N)=O
Show InChI InChI=1S/C23H21F3N4O/c1-29-11-12-30(18-8-6-17(7-9-18)23(24,25)26)21-10-5-15(13-16(21)14-29)19-3-2-4-20(28-19)22(27)31/h2-10,13H,11-12,14H2,1H3,(H2,27,31)
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400n/an/an/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) by electrophysiological assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088547
PNG
(CHEMBL3577024)
Show SMILES CNC(=O)CN1CCN(c2ccc(cc2)C(F)(F)F)c2ccc(cc2C1)-c1cccc(n1)[C@H](O)CO
Show InChI InChI=1S/C26H27F3N4O3/c1-30-25(36)15-32-11-12-33(20-8-6-19(7-9-20)26(27,28)29)23-10-5-17(13-18(23)14-32)21-3-2-4-22(31-21)24(35)16-34/h2-10,13,24,34-35H,11-12,14-16H2,1H3,(H,30,36)/t24-/m1/s1
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440n/an/an/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) by electrophysiological assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088552
PNG
(CHEMBL3577029)
Show SMILES NC(=O)N1CCN(c2ccc(cc2)C(F)(F)F)c2ccc(cc2C1)-c1cccc(n1)[C@H](O)CO
Show InChI InChI=1S/C24H23F3N4O3/c25-24(26,27)17-5-7-18(8-6-17)31-11-10-30(23(28)34)13-16-12-15(4-9-21(16)31)19-2-1-3-20(29-19)22(33)14-32/h1-9,12,22,32-33H,10-11,13-14H2,(H2,28,34)/t22-/m1/s1
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450n/an/an/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) by electrophysiological assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088551
PNG
(CHEMBL3577028)
Show SMILES OC[C@@H](O)c1cccc(n1)-c1ccc2N(CCN(CC3CC3)Cc2c1)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C27H28F3N3O2/c28-27(29,30)21-7-9-22(10-8-21)33-13-12-32(15-18-4-5-18)16-20-14-19(6-11-25(20)33)23-2-1-3-24(31-23)26(35)17-34/h1-3,6-11,14,18,26,34-35H,4-5,12-13,15-17H2/t26-/m1/s1
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550n/an/an/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) by electrophysiological assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088548
PNG
(CHEMBL3577025)
Show SMILES CC(=O)N1CCN(c2ccc(cc2)C(F)(F)F)c2ccc(cc2C1)-c1cccc(n1)[C@H](O)CO
Show InChI InChI=1S/C25H24F3N3O3/c1-16(33)30-11-12-31(20-8-6-19(7-9-20)25(26,27)28)23-10-5-17(13-18(23)14-30)21-3-2-4-22(29-21)24(34)15-32/h2-10,13,24,32,34H,11-12,14-15H2,1H3/t24-/m1/s1
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630n/an/an/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) by electrophysiological assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088541
PNG
(CHEMBL3576949)
Show SMILES NC(=O)c1cccc(n1)-c1ccc2N(CCCOc2c1)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C22H18F3N3O2/c23-22(24,25)15-6-8-16(9-7-15)28-11-2-12-30-20-13-14(5-10-19(20)28)17-3-1-4-18(27-17)21(26)29/h1,3-10,13H,2,11-12H2,(H2,26,29)
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n/an/a 340n/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) expressed in CHO cells after 45 mins by FLIPR assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088540
PNG
(CHEMBL3576948)
Show SMILES NC(=O)c1cccc(n1)-c1ccc2N(CCCCc2c1)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C23H20F3N3O/c24-23(25,26)17-8-10-18(11-9-17)29-13-2-1-4-16-14-15(7-12-21(16)29)19-5-3-6-20(28-19)22(27)30/h3,5-12,14H,1-2,4,13H2,(H2,27,30)
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n/an/a 360n/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) expressed in CHO cells after 45 mins by FLIPR assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088545
PNG
(CHEMBL3577022)
Show SMILES CC(=O)N1CCN(c2ccc(cc2)C(F)(F)F)c2ccc(cc2C1)-c1cccc(n1)C(N)=O
Show InChI InChI=1S/C24H21F3N4O2/c1-15(32)30-11-12-31(19-8-6-18(7-9-19)24(25,26)27)22-10-5-16(13-17(22)14-30)20-3-2-4-21(29-20)23(28)33/h2-10,13H,11-12,14H2,1H3,(H2,28,33)
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n/an/a 380n/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) expressed in CHO cells after 45 mins by FLIPR assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088542
PNG
(CHEMBL3576950)
Show SMILES NC(=O)c1cccc(n1)-c1ccc2N(CCOCc2c1)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C22H18F3N3O2/c23-22(24,25)16-5-7-17(8-6-16)28-10-11-30-13-15-12-14(4-9-20(15)28)18-2-1-3-19(27-18)21(26)29/h1-9,12H,10-11,13H2,(H2,26,29)
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n/an/a 400n/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) expressed in CHO cells after 45 mins by FLIPR assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088549
PNG
(CHEMBL3577026)
Show SMILES CS(=O)(=O)N1CCN(c2ccc(cc2)C(F)(F)F)c2ccc(cc2C1)-c1cccc(n1)[C@H](O)CO
Show InChI InChI=1S/C24H24F3N3O4S/c1-35(33,34)29-11-12-30(19-8-6-18(7-9-19)24(25,26)27)22-10-5-16(13-17(22)14-29)20-3-2-4-21(28-20)23(32)15-31/h2-10,13,23,31-32H,11-12,14-15H2,1H3/t23-/m1/s1
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n/an/a 470n/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) expressed in CHO cells after 45 mins by FLIPR assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088550
PNG
(CHEMBL3577027)
Show SMILES OC[C@@H](O)c1cccc(n1)-c1ccc2N(CCN(CC#N)Cc2c1)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C25H23F3N4O2/c26-25(27,28)19-5-7-20(8-6-19)32-13-12-31(11-10-29)15-18-14-17(4-9-23(18)32)21-2-1-3-22(30-21)24(34)16-33/h1-9,14,24,33-34H,11-13,15-16H2/t24-/m1/s1
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n/an/a 580n/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) expressed in CHO cells after 45 mins by FLIPR assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088544
PNG
(CHEMBL3577021)
Show SMILES CN1CCN(c2ccc(cc2)C(F)(F)F)c2ccc(cc2C1)-c1cccc(n1)C(N)=O
Show InChI InChI=1S/C23H21F3N4O/c1-29-11-12-30(18-8-6-17(7-9-18)23(24,25)26)21-10-5-15(13-16(21)14-29)19-3-2-4-20(28-19)22(27)31/h2-10,13H,11-12,14H2,1H3,(H2,27,31)
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n/an/a 610n/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) expressed in CHO cells after 45 mins by FLIPR assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088547
PNG
(CHEMBL3577024)
Show SMILES CNC(=O)CN1CCN(c2ccc(cc2)C(F)(F)F)c2ccc(cc2C1)-c1cccc(n1)[C@H](O)CO
Show InChI InChI=1S/C26H27F3N4O3/c1-30-25(36)15-32-11-12-33(20-8-6-19(7-9-20)26(27,28)29)23-10-5-17(13-18(23)14-32)21-3-2-4-22(31-21)24(35)16-34/h2-10,13,24,34-35H,11-12,14-16H2,1H3,(H,30,36)/t24-/m1/s1
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n/an/a 640n/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) expressed in CHO cells after 45 mins by FLIPR assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088548
PNG
(CHEMBL3577025)
Show SMILES CC(=O)N1CCN(c2ccc(cc2)C(F)(F)F)c2ccc(cc2C1)-c1cccc(n1)[C@H](O)CO
Show InChI InChI=1S/C25H24F3N3O3/c1-16(33)30-11-12-31(20-8-6-19(7-9-20)25(26,27)28)23-10-5-17(13-18(23)14-30)21-3-2-4-22(29-21)24(34)15-32/h2-10,13,24,32,34H,11-12,14-15H2,1H3/t24-/m1/s1
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n/an/a 660n/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) expressed in CHO cells after 45 mins by FLIPR assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088553
PNG
(CHEMBL3577030)
Show SMILES OC[C@@H](O)c1cccc(n1)-c1ccc2N(CCN(Cc3ncc[nH]3)Cc2c1)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C27H26F3N5O2/c28-27(29,30)20-5-7-21(8-6-20)35-13-12-34(16-26-31-10-11-32-26)15-19-14-18(4-9-24(19)35)22-2-1-3-23(33-22)25(37)17-36/h1-11,14,25,36-37H,12-13,15-17H2,(H,31,32)/t25-/m1/s1
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n/an/a 670n/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) expressed in CHO cells after 45 mins by FLIPR assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088539
PNG
(CHEMBL3576947)
Show SMILES NC(=O)c1cccc(n1)-c1ccc2N(CCCc2c1)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C22H18F3N3O/c23-22(24,25)16-7-9-17(10-8-16)28-12-2-3-15-13-14(6-11-20(15)28)18-4-1-5-19(27-18)21(26)29/h1,4-11,13H,2-3,12H2,(H2,26,29)
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PubMed
n/an/a 910n/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) expressed in CHO cells after 45 mins by FLIPR assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088552
PNG
(CHEMBL3577029)
Show SMILES NC(=O)N1CCN(c2ccc(cc2)C(F)(F)F)c2ccc(cc2C1)-c1cccc(n1)[C@H](O)CO
Show InChI InChI=1S/C24H23F3N4O3/c25-24(26,27)17-5-7-18(8-6-17)31-11-10-30(23(28)34)13-16-12-15(4-9-21(16)31)19-2-1-3-20(29-19)22(33)14-32/h1-9,12,22,32-33H,10-11,13-14H2,(H2,28,34)/t22-/m1/s1
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PubMed
n/an/a 970n/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) expressed in CHO cells after 45 mins by FLIPR assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088546
PNG
(CHEMBL3577023)
Show SMILES NC(=O)CN1CCN(c2ccc(cc2)C(F)(F)F)c2ccc(cc2C1)-c1cccc(n1)[C@H](O)CO
Show InChI InChI=1S/C25H25F3N4O3/c26-25(27,28)18-5-7-19(8-6-18)32-11-10-31(14-24(29)35)13-17-12-16(4-9-22(17)32)20-2-1-3-21(30-20)23(34)15-33/h1-9,12,23,33-34H,10-11,13-15H2,(H2,29,35)/t23-/m1/s1
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PubMed
n/an/a 1.05E+3n/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) expressed in CHO cells after 45 mins by FLIPR assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088551
PNG
(CHEMBL3577028)
Show SMILES OC[C@@H](O)c1cccc(n1)-c1ccc2N(CCN(CC3CC3)Cc2c1)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C27H28F3N3O2/c28-27(29,30)21-7-9-22(10-8-21)33-13-12-32(15-18-4-5-18)16-20-14-19(6-11-25(20)33)23-2-1-3-24(31-23)26(35)17-34/h1-3,6-11,14,18,26,34-35H,4-5,12-13,15-17H2/t26-/m1/s1
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PubMed
n/an/a 1.32E+3n/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) expressed in CHO cells after 45 mins by FLIPR assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088543
PNG
(CHEMBL3577020)
Show SMILES NC(=O)c1cccc(n1)-c1ccc2N(CCNCc2c1)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C22H19F3N4O/c23-22(24,25)16-5-7-17(8-6-16)29-11-10-27-13-15-12-14(4-9-20(15)29)18-2-1-3-19(28-18)21(26)30/h1-9,12,27H,10-11,13H2,(H2,26,30)
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n/an/a 1.92E+3n/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) expressed in CHO cells after 45 mins by FLIPR assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM50088538
PNG
(CHEMBL3576946)
Show SMILES NC(=O)c1cccc(n1)-c1ccc2N(CCc2c1)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C21H16F3N3O/c22-21(23,24)15-5-7-16(8-6-15)27-11-10-14-12-13(4-9-19(14)27)17-2-1-3-18(26-17)20(25)28/h1-9,12H,10-11H2,(H2,25,28)
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PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Purdue Pharma L.P.

Curated by ChEMBL


Assay Description
Inhibition of Nav1.7 (unknown origin) expressed in CHO cells after 45 mins by FLIPR assay


Bioorg Med Chem Lett 25: 48-52 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.023
BindingDB Entry DOI: 10.7270/Q2862J67
More data for this
Ligand-Target Pair