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Compile Data Set for Download or QSAR

Found 18 hits with Last Name = 'abdul wahab' and Initial = 'sm'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Butyrylcholinesterase (BuChE)


(Equus caballus (Horse))
BDBM50182486
PNG
(MALABARICONE B)
Show SMILES Oc1ccc(CCCCCCCCC(=O)c2c(O)cccc2O)cc1
Show InChI InChI=1S/C21H26O4/c22-17-14-12-16(13-15-17)8-5-3-1-2-4-6-9-18(23)21-19(24)10-7-11-20(21)25/h7,10-15,22,24-25H,1-6,8-9H2
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560n/an/an/an/an/an/an/an/a



University of Malaya

Curated by ChEMBL


Assay Description
Mixed inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Lineweaver-Burk plot analysis


Bioorg Med Chem Lett 26: 3785-92 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.046
BindingDB Entry DOI: 10.7270/Q2F47R34
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (human))
BDBM50182486
PNG
(MALABARICONE B)
Show SMILES Oc1ccc(CCCCCCCCC(=O)c2c(O)cccc2O)cc1
Show InChI InChI=1S/C21H26O4/c22-17-14-12-16(13-15-17)8-5-3-1-2-4-6-9-18(23)21-19(24)10-7-11-20(21)25/h7,10-15,22,24-25H,1-6,8-9H2
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4.33E+3n/an/an/an/an/an/an/an/a



University of Malaya

Curated by ChEMBL


Assay Description
Mixed inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Lineweaver-Burk plot analysis


Bioorg Med Chem Lett 26: 3785-92 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.046
BindingDB Entry DOI: 10.7270/Q2F47R34
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (human))
BDBM50182491
PNG
(CHEBI:69015 | MALABARICONE C | Malabaricone C)
Show SMILES Oc1ccc(CCCCCCCCC(=O)c2c(O)cccc2O)cc1O
Show InChI InChI=1S/C21H26O5/c22-16-13-12-15(14-20(16)26)8-5-3-1-2-4-6-9-17(23)21-18(24)10-7-11-19(21)25/h7,10-14,22,24-26H,1-6,8-9H2
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5.86E+3n/an/an/an/an/an/an/an/a



University of Malaya

Curated by ChEMBL


Assay Description
Mixed inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Lineweaver-Burk plot analysis


Bioorg Med Chem Lett 26: 3785-92 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.046
BindingDB Entry DOI: 10.7270/Q2F47R34
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BuChE)


(Equus caballus (Horse))
BDBM50182491
PNG
(CHEBI:69015 | MALABARICONE C | Malabaricone C)
Show SMILES Oc1ccc(CCCCCCCCC(=O)c2c(O)cccc2O)cc1O
Show InChI InChI=1S/C21H26O5/c22-16-13-12-15(14-20(16)26)8-5-3-1-2-4-6-9-17(23)21-18(24)10-7-11-19(21)25/h7,10-14,22,24-26H,1-6,8-9H2
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1.15E+4n/an/an/an/an/an/an/an/a



University of Malaya

Curated by ChEMBL


Assay Description
Mixed inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Lineweaver-Burk plot analysis


Bioorg Med Chem Lett 26: 3785-92 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.046
BindingDB Entry DOI: 10.7270/Q2F47R34
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (human))
BDBM50004000
PNG
((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Show SMILES CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1
Show InChI InChI=1S/C15H21N3O2/c1-15-7-8-17(3)13(15)18(4)12-6-5-10(9-11(12)15)20-14(19)16-2/h5-6,9,13H,7-8H2,1-4H3,(H,16,19)/t13-,15+/m1/s1
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n/an/a 80n/an/an/an/an/an/a



University of Malaya

Curated by ChEMBL


Assay Description
Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assay


Bioorg Med Chem Lett 26: 3785-92 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.046
BindingDB Entry DOI: 10.7270/Q2F47R34
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BuChE)


(Equus caballus (Horse))
BDBM50004000
PNG
((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Show SMILES CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1
Show InChI InChI=1S/C15H21N3O2/c1-15-7-8-17(3)13(15)18(4)12-6-5-10(9-11(12)15)20-14(19)16-2/h5-6,9,13H,7-8H2,1-4H3,(H,16,19)/t13-,15+/m1/s1
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n/an/a 220n/an/an/an/an/an/a



University of Malaya

Curated by ChEMBL


Assay Description
Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assay


Bioorg Med Chem Lett 26: 3785-92 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.046
BindingDB Entry DOI: 10.7270/Q2F47R34
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (human))
BDBM50182487
PNG
(MALABARICONE A | Malabaricone A)
Show SMILES Oc1cccc(O)c1C(=O)CCCCCCCCc1ccccc1
Show InChI InChI=1S/C21H26O3/c22-18(21-19(23)15-10-16-20(21)24)14-9-4-2-1-3-6-11-17-12-7-5-8-13-17/h5,7-8,10,12-13,15-16,23-24H,1-4,6,9,11,14H2
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n/an/a 1.31E+3n/an/an/an/an/an/a



University of Malaya

Curated by ChEMBL


Assay Description
Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assay


Bioorg Med Chem Lett 26: 3785-92 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.046
BindingDB Entry DOI: 10.7270/Q2F47R34
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BuChE)


(Equus caballus (Horse))
BDBM50182486
PNG
(MALABARICONE B)
Show SMILES Oc1ccc(CCCCCCCCC(=O)c2c(O)cccc2O)cc1
Show InChI InChI=1S/C21H26O4/c22-17-14-12-16(13-15-17)8-5-3-1-2-4-6-9-18(23)21-19(24)10-7-11-20(21)25/h7,10-15,22,24-25H,1-6,8-9H2
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n/an/a 1.76E+3n/an/an/an/an/an/a



University of Malaya

Curated by ChEMBL


Assay Description
Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assay


Bioorg Med Chem Lett 26: 3785-92 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.046
BindingDB Entry DOI: 10.7270/Q2F47R34
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (human))
BDBM50182486
PNG
(MALABARICONE B)
Show SMILES Oc1ccc(CCCCCCCCC(=O)c2c(O)cccc2O)cc1
Show InChI InChI=1S/C21H26O4/c22-17-14-12-16(13-15-17)8-5-3-1-2-4-6-9-18(23)21-19(24)10-7-11-20(21)25/h7,10-15,22,24-25H,1-6,8-9H2
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n/an/a 1.84E+3n/an/an/an/an/an/a



University of Malaya

Curated by ChEMBL


Assay Description
Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assay


Bioorg Med Chem Lett 26: 3785-92 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.046
BindingDB Entry DOI: 10.7270/Q2F47R34
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (human))
BDBM50182491
PNG
(CHEBI:69015 | MALABARICONE C | Malabaricone C)
Show SMILES Oc1ccc(CCCCCCCCC(=O)c2c(O)cccc2O)cc1O
Show InChI InChI=1S/C21H26O5/c22-16-13-12-15(14-20(16)26)8-5-3-1-2-4-6-9-17(23)21-18(24)10-7-11-19(21)25/h7,10-14,22,24-26H,1-6,8-9H2
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n/an/a 1.94E+3n/an/an/an/an/an/a



University of Malaya

Curated by ChEMBL


Assay Description
Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assay


Bioorg Med Chem Lett 26: 3785-92 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.046
BindingDB Entry DOI: 10.7270/Q2F47R34
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BuChE)


(Equus caballus (Horse))
BDBM50182491
PNG
(CHEBI:69015 | MALABARICONE C | Malabaricone C)
Show SMILES Oc1ccc(CCCCCCCCC(=O)c2c(O)cccc2O)cc1O
Show InChI InChI=1S/C21H26O5/c22-16-13-12-15(14-20(16)26)8-5-3-1-2-4-6-9-17(23)21-18(24)10-7-11-19(21)25/h7,10-14,22,24-26H,1-6,8-9H2
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n/an/a 2.80E+3n/an/an/an/an/an/a



University of Malaya

Curated by ChEMBL


Assay Description
Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assay


Bioorg Med Chem Lett 26: 3785-92 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.046
BindingDB Entry DOI: 10.7270/Q2F47R34
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (human))
BDBM50182488
PNG
(CHEMBL3819036)
Show SMILES Oc1ccc(CCCCCCCCC(=O)c2c(O)cc(O)cc2O)cc1
Show InChI InChI=1S/C21H26O5/c22-16-11-9-15(10-12-16)7-5-3-1-2-4-6-8-18(24)21-19(25)13-17(23)14-20(21)26/h9-14,22-23,25-26H,1-8H2
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n/an/a 6.44E+3n/an/an/an/an/an/a



University of Malaya

Curated by ChEMBL


Assay Description
Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assay


Bioorg Med Chem Lett 26: 3785-92 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.046
BindingDB Entry DOI: 10.7270/Q2F47R34
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BuChE)


(Equus caballus (Horse))
BDBM50182488
PNG
(CHEMBL3819036)
Show SMILES Oc1ccc(CCCCCCCCC(=O)c2c(O)cc(O)cc2O)cc1
Show InChI InChI=1S/C21H26O5/c22-16-11-9-15(10-12-16)7-5-3-1-2-4-6-8-18(24)21-19(25)13-17(23)14-20(21)26/h9-14,22-23,25-26H,1-8H2
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n/an/a 6.65E+3n/an/an/an/an/an/a



University of Malaya

Curated by ChEMBL


Assay Description
Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assay


Bioorg Med Chem Lett 26: 3785-92 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.046
BindingDB Entry DOI: 10.7270/Q2F47R34
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BuChE)


(Equus caballus (Horse))
BDBM50182489
PNG
(CHEMBL3818374)
Show SMILES Oc1ccc(CCCCCCCCC(c2ccc(O)c(C(=O)CCCCCCCCc3ccc(O)c(O)c3)c2O)c2c(O)cccc2O)cc1O
Show InChI InChI=1S/C42H52O9/c43-32-23-20-28(26-38(32)49)14-9-5-1-3-7-11-16-30(40-34(45)18-13-19-35(40)46)31-22-25-37(48)41(42(31)51)36(47)17-12-8-4-2-6-10-15-29-21-24-33(44)39(50)27-29/h13,18-27,30,43-46,48-51H,1-12,14-17H2
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n/an/a 1.05E+4n/an/an/an/an/an/a



University of Malaya

Curated by ChEMBL


Assay Description
Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assay


Bioorg Med Chem Lett 26: 3785-92 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.046
BindingDB Entry DOI: 10.7270/Q2F47R34
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BuChE)


(Equus caballus (Horse))
BDBM50182490
PNG
(CHEMBL3819024)
Show SMILES Oc1ccc(CCCCCCCCC(c2ccc(O)c(C(=O)CCCCCCCCc3ccc(O)c(O)c3)c2O)c2c(O)cccc2O)cc1
Show InChI InChI=1S/C42H52O8/c43-31-23-20-29(21-24-31)14-9-5-1-3-7-11-16-32(40-35(45)18-13-19-36(40)46)33-25-27-38(48)41(42(33)50)37(47)17-12-8-4-2-6-10-15-30-22-26-34(44)39(49)28-30/h13,18-28,32,43-46,48-50H,1-12,14-17H2
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n/an/a 1.25E+4n/an/an/an/an/an/a



University of Malaya

Curated by ChEMBL


Assay Description
Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assay


Bioorg Med Chem Lett 26: 3785-92 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.046
BindingDB Entry DOI: 10.7270/Q2F47R34
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (human))
BDBM50182489
PNG
(CHEMBL3818374)
Show SMILES Oc1ccc(CCCCCCCCC(c2ccc(O)c(C(=O)CCCCCCCCc3ccc(O)c(O)c3)c2O)c2c(O)cccc2O)cc1O
Show InChI InChI=1S/C42H52O9/c43-32-23-20-28(26-38(32)49)14-9-5-1-3-7-11-16-30(40-34(45)18-13-19-35(40)46)31-22-25-37(48)41(42(31)51)36(47)17-12-8-4-2-6-10-15-29-21-24-33(44)39(50)27-29/h13,18-27,30,43-46,48-51H,1-12,14-17H2
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n/an/a 1.27E+4n/an/an/an/an/an/a



University of Malaya

Curated by ChEMBL


Assay Description
Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assay


Bioorg Med Chem Lett 26: 3785-92 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.046
BindingDB Entry DOI: 10.7270/Q2F47R34
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (human))
BDBM50182490
PNG
(CHEMBL3819024)
Show SMILES Oc1ccc(CCCCCCCCC(c2ccc(O)c(C(=O)CCCCCCCCc3ccc(O)c(O)c3)c2O)c2c(O)cccc2O)cc1
Show InChI InChI=1S/C42H52O8/c43-31-23-20-29(21-24-31)14-9-5-1-3-7-11-16-32(40-35(45)18-13-19-36(40)46)33-25-27-38(48)41(42(33)50)37(47)17-12-8-4-2-6-10-15-30-22-26-34(44)39(49)28-30/h13,18-28,32,43-46,48-50H,1-12,14-17H2
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n/an/a 3.07E+4n/an/an/an/an/an/a



University of Malaya

Curated by ChEMBL


Assay Description
Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate incubated for 30 mins by Ellman's microplate assay


Bioorg Med Chem Lett 26: 3785-92 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.046
BindingDB Entry DOI: 10.7270/Q2F47R34
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BuChE)


(Equus caballus (Horse))
BDBM50182487
PNG
(MALABARICONE A | Malabaricone A)
Show SMILES Oc1cccc(O)c1C(=O)CCCCCCCCc1ccccc1
Show InChI InChI=1S/C21H26O3/c22-18(21-19(23)15-10-16-20(21)24)14-9-4-2-1-3-6-11-17-12-7-5-8-13-17/h5,7-8,10,12-13,15-16,23-24H,1-4,6,9,11,14H2
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n/an/a 3.92E+4n/an/an/an/an/an/a



University of Malaya

Curated by ChEMBL


Assay Description
Inhibition of equine serum BChE using S-butyrylthiocholine chloride as substrate incubated for 30 mins by Ellman's microplate assay


Bioorg Med Chem Lett 26: 3785-92 (2016)


Article DOI: 10.1016/j.bmcl.2016.05.046
BindingDB Entry DOI: 10.7270/Q2F47R34
More data for this
Ligand-Target Pair