BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 11 hits with Last Name = 'abrahim-vieira' and Initial = 'b'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kallikrein 1


(Homo sapiens (Human))
BDBM50205620
PNG
(CHEMBL3943212)
Show SMILES CC(C)(N([C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(=O)Cc1ccc(O)cc1)C(=O)NC1CCCCC1
Show InChI InChI=1S/C31H40N2O6/c1-31(2,30(36)32-23-11-7-4-8-12-23)33(27(35)17-21-13-15-24(34)16-14-21)25-19-38-29-26(20-39-28(25)29)37-18-22-9-5-3-6-10-22/h3,5-6,9-10,13-16,23,25-26,28-29,34H,4,7-8,11-12,17-20H2,1-2H3,(H,32,36)/t25-,26+,28+,29+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
3.10E+3n/an/an/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Competitive inhibition of recombinant human KLK1 expressed in baculovirus/insect cell expression system using Abz-KLRSSKQ-EDDnp peptide as substrate ...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
BindingDB Entry DOI: 10.7270/Q2WW7KNV
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
BDBM50205620
PNG
(CHEMBL3943212)
Show SMILES CC(C)(N([C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(=O)Cc1ccc(O)cc1)C(=O)NC1CCCCC1
Show InChI InChI=1S/C31H40N2O6/c1-31(2,30(36)32-23-11-7-4-8-12-23)33(27(35)17-21-13-15-24(34)16-14-21)25-19-38-29-26(20-39-28(25)29)37-18-22-9-5-3-6-10-22/h3,5-6,9-10,13-16,23,25-26,28-29,34H,4,7-8,11-12,17-20H2,1-2H3,(H,32,36)/t25-,26+,28+,29+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK1 expressed in baculovirus/insect cell expression system using Abz-KLRSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
BindingDB Entry DOI: 10.7270/Q2WW7KNV
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
BDBM50205625
PNG
(CHEMBL3901491)
Show SMILES CC(C)(N([C@H]1CO[C@@H]2[C@H](CO[C@H]12)N(C(=O)Cc1ccc(O)cc1)C(C)(C)C(=O)NC1CCCCC1)C(=O)Cc1ccc(O)cc1)C(=O)NC1CCCCC1
Show InChI InChI=1S/C42H58N4O8/c1-41(2,39(51)43-29-11-7-5-8-12-29)45(35(49)23-27-15-19-31(47)20-16-27)33-25-53-38-34(26-54-37(33)38)46(36(50)24-28-17-21-32(48)22-18-28)42(3,4)40(52)44-30-13-9-6-10-14-30/h15-22,29-30,33-34,37-38,47-48H,5-14,23-26H2,1-4H3,(H,43,51)(H,44,52)/t33-,34-,37+,38+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.26E+4n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK1 expressed in baculovirus/insect cell expression system using Abz-KLRSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
BindingDB Entry DOI: 10.7270/Q2WW7KNV
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
BDBM50205624
PNG
(CHEMBL3963267)
Show SMILES COc1ccc(CC(=O)N([C@H]2CO[C@@H]3[C@@H](CO[C@H]23)OCc2ccccc2)C(C)(C)C(=O)NC2CCCCC2)cc1
Show InChI InChI=1S/C32H42N2O6/c1-32(2,31(36)33-24-12-8-5-9-13-24)34(28(35)18-22-14-16-25(37-3)17-15-22)26-20-39-30-27(21-40-29(26)30)38-19-23-10-6-4-7-11-23/h4,6-7,10-11,14-17,24,26-27,29-30H,5,8-9,12-13,18-21H2,1-3H3,(H,33,36)/t26-,27+,29+,30+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.25E+5n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK1 expressed in baculovirus/insect cell expression system using Abz-KLRSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
BindingDB Entry DOI: 10.7270/Q2WW7KNV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50205625
PNG
(CHEMBL3901491)
Show SMILES CC(C)(N([C@H]1CO[C@@H]2[C@H](CO[C@H]12)N(C(=O)Cc1ccc(O)cc1)C(C)(C)C(=O)NC1CCCCC1)C(=O)Cc1ccc(O)cc1)C(=O)NC1CCCCC1
Show InChI InChI=1S/C42H58N4O8/c1-41(2,39(51)43-29-11-7-5-8-12-29)45(35(49)23-27-15-19-31(47)20-16-27)33-25-53-38-34(26-54-37(33)38)46(36(50)24-28-17-21-32(48)22-18-28)42(3,4)40(52)44-30-13-9-6-10-14-30/h15-22,29-30,33-34,37-38,47-48H,5-14,23-26H2,1-4H3,(H,43,51)(H,44,52)/t33-,34-,37+,38+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.33E+5n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK7 expressed in baculovirus/insect cell expression system using Abz-KLYSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
BindingDB Entry DOI: 10.7270/Q2WW7KNV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50205623
PNG
(CHEMBL3951954)
Show SMILES CC(C)(N([C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(=O)Cc1ccc(F)cc1)C(=O)NC1CCCCC1
Show InChI InChI=1S/C31H39FN2O5/c1-31(2,30(36)33-24-11-7-4-8-12-24)34(27(35)17-21-13-15-23(32)16-14-21)25-19-38-29-26(20-39-28(25)29)37-18-22-9-5-3-6-10-22/h3,5-6,9-10,13-16,24-26,28-29H,4,7-8,11-12,17-20H2,1-2H3,(H,33,36)/t25-,26+,28+,29+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.85E+5n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK7 expressed in baculovirus/insect cell expression system using Abz-KLYSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
BindingDB Entry DOI: 10.7270/Q2WW7KNV
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
BDBM50205623
PNG
(CHEMBL3951954)
Show SMILES CC(C)(N([C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(=O)Cc1ccc(F)cc1)C(=O)NC1CCCCC1
Show InChI InChI=1S/C31H39FN2O5/c1-31(2,30(36)33-24-11-7-4-8-12-24)34(27(35)17-21-13-15-23(32)16-14-21)25-19-38-29-26(20-39-28(25)29)37-18-22-9-5-3-6-10-22/h3,5-6,9-10,13-16,24-26,28-29H,4,7-8,11-12,17-20H2,1-2H3,(H,33,36)/t25-,26+,28+,29+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.21E+5n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK1 expressed in baculovirus/insect cell expression system using Abz-KLRSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
BindingDB Entry DOI: 10.7270/Q2WW7KNV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50205620
PNG
(CHEMBL3943212)
Show SMILES CC(C)(N([C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(=O)Cc1ccc(O)cc1)C(=O)NC1CCCCC1
Show InChI InChI=1S/C31H40N2O6/c1-31(2,30(36)32-23-11-7-4-8-12-23)33(27(35)17-21-13-15-24(34)16-14-21)25-19-38-29-26(20-39-28(25)29)37-18-22-9-5-3-6-10-22/h3,5-6,9-10,13-16,23,25-26,28-29,34H,4,7-8,11-12,17-20H2,1-2H3,(H,32,36)/t25-,26+,28+,29+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.49E+5n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK7 expressed in baculovirus/insect cell expression system using Abz-KLYSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
BindingDB Entry DOI: 10.7270/Q2WW7KNV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50205624
PNG
(CHEMBL3963267)
Show SMILES COc1ccc(CC(=O)N([C@H]2CO[C@@H]3[C@@H](CO[C@H]23)OCc2ccccc2)C(C)(C)C(=O)NC2CCCCC2)cc1
Show InChI InChI=1S/C32H42N2O6/c1-32(2,31(36)33-24-12-8-5-9-13-24)34(28(35)18-22-14-16-25(37-3)17-15-22)26-20-39-30-27(21-40-29(26)30)38-19-23-10-6-4-7-11-23/h4,6-7,10-11,14-17,24,26-27,29-30H,5,8-9,12-13,18-21H2,1-3H3,(H,33,36)/t26-,27+,29+,30+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.72E+5n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK7 expressed in baculovirus/insect cell expression system using Abz-KLYSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
BindingDB Entry DOI: 10.7270/Q2WW7KNV
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
BDBM50205621
PNG
(CHEMBL3891631)
Show SMILES CC(C)(N([C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(=O)c1ccccc1)C(=O)NC1CCCCC1
Show InChI InChI=1S/C30H38N2O5/c1-30(2,29(34)31-23-16-10-5-11-17-23)32(28(33)22-14-8-4-9-15-22)24-19-36-27-25(20-37-26(24)27)35-18-21-12-6-3-7-13-21/h3-4,6-9,12-15,23-27H,5,10-11,16-20H2,1-2H3,(H,31,34)/t24-,25+,26+,27+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.00E+5n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK1 expressed in baculovirus/insect cell expression system using Abz-KLRSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
BindingDB Entry DOI: 10.7270/Q2WW7KNV
More data for this
Ligand-Target Pair
Kallikrein 7


(Homo sapiens)
BDBM50205621
PNG
(CHEMBL3891631)
Show SMILES CC(C)(N([C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(=O)c1ccccc1)C(=O)NC1CCCCC1
Show InChI InChI=1S/C30H38N2O5/c1-30(2,29(34)31-23-16-10-5-11-17-23)32(28(33)22-14-8-4-9-15-22)24-19-36-27-25(20-37-26(24)27)35-18-21-12-6-3-7-13-21/h3-4,6-9,12-15,23-27H,5,10-11,16-20H2,1-2H3,(H,31,34)/t24-,25+,26+,27+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.72E+5n/an/an/an/an/an/a



Universidade Federal Fluminense

Curated by ChEMBL


Assay Description
Inhibition of recombinant human KLK7 expressed in baculovirus/insect cell expression system using Abz-KLYSSKQ-EDDnp peptide as substrate preincubated...


Bioorg Med Chem Lett 27: 314-318 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.051
BindingDB Entry DOI: 10.7270/Q2WW7KNV
More data for this
Ligand-Target Pair