BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 9 hits with Last Name = 'ackerman' and Initial = 'c'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostatic acid phosphatase


(Homo sapiens)
BDBM50289997
PNG
((Benzylamino-naphthalen-1-yl-methyl)-phosphonic ac...)
Show SMILES OP(O)(=O)C(NCc1ccccc1)c1cccc2ccccc12
Show InChI InChI=1S/C18H18NO3P/c20-23(21,22)18(19-13-14-7-2-1-3-8-14)17-12-6-10-15-9-4-5-11-16(15)17/h1-12,18-19H,13H2,(H2,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 8.60n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for its inhibitory activity against human prostatic acid phosphatase


Bioorg Med Chem Lett 7: 2169-2172 (1997)


Article DOI: 10.1016/S0960-894X(97)00390-9
BindingDB Entry DOI: 10.7270/Q2416X2J
More data for this
Ligand-Target Pair
Tyrosine-Protein Phosphatase (CD45)


(Homo sapiens (Human))
BDBM50289994
PNG
(CHEMBL68541 | [(2-Cyclohexylsulfanyl-5-nitro-pheny...)
Show SMILES OP(O)(O)C(=O)c1cc(ccc1SC1CCCCC1)[N+]([O-])=O
Show InChI InChI=1S/C13H18NO6PS/c15-13(21(18,19)20)11-8-9(14(16)17)6-7-12(11)22-10-4-2-1-3-5-10/h6-8,10,18-21H,1-5H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 1.20E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for inhibitory activity against CD45 protein-tyrosine phosphatase of Jurkat cell membrane at 1000 microM


Bioorg Med Chem Lett 7: 2169-2172 (1997)


Article DOI: 10.1016/S0960-894X(97)00390-9
BindingDB Entry DOI: 10.7270/Q2416X2J
More data for this
Ligand-Target Pair
Tyrosine-Protein Phosphatase (CD45)


(Homo sapiens (Human))
BDBM50289995
PNG
(CHEMBL305414 | [(2-Azido-5-nitro-phenyl)-hydroxy-m...)
Show SMILES OP(O)(O)C(=O)c1cc(ccc1N=[N+]=[N-])[N+]([O-])=O
Show InChI InChI=1S/C7H7N4O6P/c8-10-9-6-2-1-4(11(13)14)3-5(6)7(12)18(15,16)17/h1-3,15-18H
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 8.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for inhibitory activity against CD-45 tyrosine phosphatase of Jurkat cell membrane at 1000 microM


Bioorg Med Chem Lett 7: 2169-2172 (1997)


Article DOI: 10.1016/S0960-894X(97)00390-9
BindingDB Entry DOI: 10.7270/Q2416X2J
More data for this
Ligand-Target Pair
Tyrosine-Protein Phosphatase (CD45)


(Homo sapiens (Human))
BDBM50289996
PNG
(CHEMBL302032 | [Hydroxy-(3-nitro-phenyl)-methyl]-p...)
Show SMILES OP(O)(O)C(=O)c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C7H8NO6P/c9-7(15(12,13)14)5-2-1-3-6(4-5)8(10)11/h1-4,12-15H
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for inhibitory activity against CD45 protein-tyrosine phosphatase of Jurkat cell membrane at 1000 microM


Bioorg Med Chem Lett 7: 2169-2172 (1997)


Article DOI: 10.1016/S0960-894X(97)00390-9
BindingDB Entry DOI: 10.7270/Q2416X2J
More data for this
Ligand-Target Pair
Prostatic acid phosphatase


(Homo sapiens)
BDBM50288656
PNG
((Phenyl-m-tolyl-methyl)-phosphonic acid | CHEMBL71...)
Show SMILES Cc1cccc(c1)C(c1ccccc1)P(O)(O)=O
Show InChI InChI=1S/C14H15O3P/c1-11-6-5-9-13(10-11)14(18(15,16)17)12-7-3-2-4-8-12/h2-10,14H,1H3,(H2,15,16,17)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 1.40E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for its inhibitory activity against human prostatic acid phosphatase


Bioorg Med Chem Lett 7: 2169-2172 (1997)


Article DOI: 10.1016/S0960-894X(97)00390-9
BindingDB Entry DOI: 10.7270/Q2416X2J
More data for this
Ligand-Target Pair
Tyrosine-Protein Phosphatase (CD45)


(Homo sapiens (Human))
BDBM50289992
PNG
(CHEMBL69168 | [(2-Chloro-5-nitro-phenyl)-hydroxy-m...)
Show SMILES OP(O)(O)C(=O)c1cc(ccc1Cl)[N+]([O-])=O
Show InChI InChI=1S/C7H7ClNO6P/c8-6-2-1-4(9(11)12)3-5(6)7(10)16(13,14)15/h1-3,13-16H
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 2.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for inhibitory activity against CD45 protein-tyrosine phosphatase of Jurkat cell membrane at 1000 microM


Bioorg Med Chem Lett 7: 2169-2172 (1997)


Article DOI: 10.1016/S0960-894X(97)00390-9
BindingDB Entry DOI: 10.7270/Q2416X2J
More data for this
Ligand-Target Pair
Tyrosine-Protein Phosphatase (CD45)


(Homo sapiens (Human))
BDBM50289998
PNG
(CHEMBL307095 | [Hydroxy-(4-nitro-phenyl)-methyl]-p...)
Show SMILES OP(O)(O)C(=O)c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C7H8NO6P/c9-7(15(12,13)14)5-1-3-6(4-2-5)8(10)11/h1-4,12-15H
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 2.80E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for inhibitory activity against CD45 protein-tyrosine phosphatase of Jurkat cell membrane at 1000 microM


Bioorg Med Chem Lett 7: 2169-2172 (1997)


Article DOI: 10.1016/S0960-894X(97)00390-9
BindingDB Entry DOI: 10.7270/Q2416X2J
More data for this
Ligand-Target Pair
Tyrosine-Protein Phosphatase (CD45)


(Homo sapiens (Human))
BDBM50289993
PNG
(CHEMBL308474 | [Hydroxy-(5-nitro-thiophen-3-yl)-me...)
Show SMILES OC(c1csc(c1)[N+]([O-])=O)[P+](O)(O)[O-]
Show InChI InChI=1S/C5H6NO6PS/c7-5(13(10,11)12)3-1-4(6(8)9)14-2-3/h1-2,5,7H,(H2,10,11,12)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 3.80E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for inhibitory activity against CD45 protein-tyrosine phosphatase of Jurkat cell membrane at 1000 microM


Bioorg Med Chem Lett 7: 2169-2172 (1997)


Article DOI: 10.1016/S0960-894X(97)00390-9
BindingDB Entry DOI: 10.7270/Q2416X2J
More data for this
Ligand-Target Pair
Tyrosine-Protein Phosphatase (CD45)


(Homo sapiens (Human))
BDBM50289999
PNG
(CHEMBL309125 | [1-Hydroxy-1-(3-nitro-phenyl)-ethyl...)
Show SMILES CC(O)(c1cccc(c1)[N+]([O-])=O)P(O)(O)=O
Show InChI InChI=1S/C8H10NO6P/c1-8(10,16(13,14)15)6-3-2-4-7(5-6)9(11)12/h2-5,10H,1H3,(H2,13,14,15)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 5.80E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for inhibitory activity against CD45 protein-tyrosine phosphatase of Jurkat cell membrane at 1000 microM


Bioorg Med Chem Lett 7: 2169-2172 (1997)


Article DOI: 10.1016/S0960-894X(97)00390-9
BindingDB Entry DOI: 10.7270/Q2416X2J
More data for this
Ligand-Target Pair