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Compile Data Set for Download or QSAR

Found 73 hits with Last Name = 'acosta-burruel' and Initial = 'm'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369783
PNG
(CHEMBL1203902)
Show SMILES Oc1ccc(cc1)C1=CCN(CCCCc2ccccc2)CC1
Show InChI InChI=1S/C21H25NO/c23-21-11-9-19(10-12-21)20-13-16-22(17-14-20)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-13,23H,4-5,8,14-17H2
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n/an/a 11n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50085922
PNG
(4-(4-Hydroxy-phenyl)-1-(4-phenyl-butyl)-piperidin-...)
Show SMILES Oc1ccc(cc1)C1(O)CCN(CCCCc2ccccc2)CC1
Show InChI InChI=1S/C21H27NO2/c23-20-11-9-19(10-12-20)21(24)13-16-22(17-14-21)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,23-24H,4-5,8,13-17H2
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n/an/a 12n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50085933
PNG
(4-[1-(5-Phenyl-pentyl)-pyrrolidin-3-yl]-phenol | C...)
Show SMILES Oc1ccc(cc1)C1CCN(CCCCCc2ccccc2)C1
Show InChI InChI=1S/C21H27NO/c23-21-12-10-19(11-13-21)20-14-16-22(17-20)15-6-2-5-9-18-7-3-1-4-8-18/h1,3-4,7-8,10-13,20,23H,2,5-6,9,14-17H2
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n/an/a 17n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50085927
PNG
(4-[1-(2-Hydroxy-4-phenyl-butyl)-piperidin-4-yl]-ph...)
Show SMILES OC(CCc1ccccc1)CN1CCC(CC1)c1ccc(O)cc1
Show InChI InChI=1S/C21H27NO2/c23-20-10-7-18(8-11-20)19-12-14-22(15-13-19)16-21(24)9-6-17-4-2-1-3-5-17/h1-5,7-8,10-11,19,21,23-24H,6,9,12-16H2
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n/an/a 19n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369786
PNG
(CHEMBL1201889)
Show SMILES Oc1ccc(cc1)C1CCN(CCOCc2ccccc2)CC1
Show InChI InChI=1S/C20H25NO2/c22-20-8-6-18(7-9-20)19-10-12-21(13-11-19)14-15-23-16-17-4-2-1-3-5-17/h1-9,19,22H,10-16H2
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n/an/a 19n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369791
PNG
(CHEMBL1202296)
Show SMILES Oc1ccc(cc1)C1CCN(CCCCc2ccccc2)CC1
Show InChI InChI=1S/C21H27NO/c23-21-11-9-19(10-12-21)20-13-16-22(17-14-20)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,20,23H,4-5,8,13-17H2
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n/an/a 22n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50085929
PNG
(4-(4-Hydroxy-phenyl)-1-(2-hydroxy-4-phenyl-butyl)-...)
Show SMILES OC(CCc1ccccc1)CN1CCC(O)(CC1)c1ccc(O)cc1
Show InChI InChI=1S/C21H27NO3/c23-19-10-7-18(8-11-19)21(25)12-14-22(15-13-21)16-20(24)9-6-17-4-2-1-3-5-17/h1-5,7-8,10-11,20,23-25H,6,9,12-16H2
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n/an/a 26n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50085921
PNG
(4-[1-(3-Phenyl-propyl)-piperidin-4-ylmethyl]-pheno...)
Show SMILES Oc1ccc(CC2CCN(CCCc3ccccc3)CC2)cc1
Show InChI InChI=1S/C21H27NO/c23-21-10-8-19(9-11-21)17-20-12-15-22(16-13-20)14-4-7-18-5-2-1-3-6-18/h1-3,5-6,8-11,20,23H,4,7,12-17H2
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n/an/a 59n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369784
PNG
(CHEMBL1202295)
Show SMILES Oc1ccc(CC2CCN(CCCCc3ccccc3)CC2)cc1
Show InChI InChI=1S/C22H29NO/c24-22-11-9-20(10-12-22)18-21-13-16-23(17-14-21)15-5-4-8-19-6-2-1-3-7-19/h1-3,6-7,9-12,21,24H,4-5,8,13-18H2
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n/an/a 71n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369782
PNG
(CHEMBL1203909)
Show SMILES Oc1ccc(cc1)C1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C20H25NO/c22-20-10-8-18(9-11-20)19-12-15-21(16-13-19)14-4-7-17-5-2-1-3-6-17/h1-3,5-6,8-11,19,22H,4,7,12-16H2
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n/an/a 74n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369787
PNG
(CHEMBL1203901)
Show SMILES Oc1ccc(cc1)C1CCN(CCCCCc2ccccc2)CC1
Show InChI InChI=1S/C22H29NO/c24-22-12-10-20(11-13-22)21-14-17-23(18-15-21)16-6-2-5-9-19-7-3-1-4-8-19/h1,3-4,7-8,10-13,21,24H,2,5-6,9,14-18H2
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n/an/a 75n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50085923
PNG
(4-[1-(4-Phenyl-butyl)-pyrrolidin-3-yl]-phenol | CH...)
Show SMILES Oc1ccc(cc1)C1CCN(CCCCc2ccccc2)C1
Show InChI InChI=1S/C20H25NO/c22-20-11-9-18(10-12-20)19-13-15-21(16-19)14-5-4-8-17-6-2-1-3-7-17/h1-3,6-7,9-12,19,22H,4-5,8,13-16H2
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n/an/a 130n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50085930
PNG
(4-[1-(3-Phenyl-prop-2-ynyl)-piperidin-4-ylmethyl]-...)
Show SMILES Oc1ccc(CC2CCN(CC#Cc3ccccc3)CC2)cc1
Show InChI InChI=1S/C21H23NO/c23-21-10-8-19(9-11-21)17-20-12-15-22(16-13-20)14-4-7-18-5-2-1-3-6-18/h1-3,5-6,8-11,20,23H,12-17H2
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n/an/a 180n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369790
PNG
(CHEMBL1203914)
Show SMILES Oc1ccc(CCCCN2CCC(CC2)c2ccccc2)cc1
Show InChI InChI=1S/C21H27NO/c23-21-11-9-18(10-12-21)6-4-5-15-22-16-13-20(14-17-22)19-7-2-1-3-8-19/h1-3,7-12,20,23H,4-6,13-17H2
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n/an/a 230n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50369789
PNG
(CHEMBL1203894)
Show SMILES COc1ccc(cc1)C1CCN(CCCCc2ccccc2)CC1
Show InChI InChI=1S/C22H29NO/c1-24-22-12-10-20(11-13-22)21-14-17-23(18-15-21)16-6-5-9-19-7-3-2-4-8-19/h2-4,7-8,10-13,21H,5-6,9,14-18H2,1H3
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n/an/a 410n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-raclopride binding at Dopamine receptor D2 in rat brain membranes.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50085925
PNG
(4-[1-(4-Phenyl-but-3-ynyl)-piperidin-4-ylmethyl]-p...)
Show SMILES Oc1ccc(CC2CCN(CCC#Cc3ccccc3)CC2)cc1
Show InChI InChI=1S/C22H25NO/c24-22-11-9-20(10-12-22)18-21-13-16-23(17-14-21)15-5-4-8-19-6-2-1-3-7-19/h1-3,6-7,9-12,21,24H,5,13-18H2
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n/an/a 800n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50369791
PNG
(CHEMBL1202296)
Show SMILES Oc1ccc(cc1)C1CCN(CCCCc2ccccc2)CC1
Show InChI InChI=1S/C21H27NO/c23-21-11-9-19(10-12-21)20-13-16-22(17-14-20)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,20,23H,4-5,8,13-17H2
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n/an/a 1.20E+3n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-raclopride binding at Dopamine receptor D2 in rat brain membranes.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
GABA receptor gamma-1 subunit


(Rattus norvegicus)
BDBM50454526
PNG
(CHEMBL3138293)
Show SMILES CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@](O)(CC[C@]4(C)[C@H]3CC[C@]12C)C#Cc1ccc(C=O)cc1
Show InChI InChI=1S/C30H38O3/c1-20(32)25-10-11-26-24-9-8-23-18-30(33,15-12-21-4-6-22(19-31)7-5-21)17-16-28(23,2)27(24)13-14-29(25,26)3/h4-7,19,23-27,33H,8-11,13-14,16-18H2,1-3H3/t23-,24+,25-,26+,27+,28+,29-,30-/m1/s1
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n/an/a 1.60E+3n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro for inhibition of [35S]TBPS binding in rat brain cortical membranes in the presence of 5 uM GABA in two-component inhibition curve


J Med Chem 40: 73-84 (1997)


Article DOI: 10.1021/jm9605344
BindingDB Entry DOI: 10.7270/Q2CN731X
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50007400
PNG
(4-Phenyl-1-(4-phenyl-butyl)-piperidine | 4-Phenyl-...)
Show SMILES C(CCc1ccccc1)CN1CCC(CC1)c1ccccc1
Show InChI InChI=1S/C21H27N/c1-3-9-19(10-4-1)11-7-8-16-22-17-14-21(15-18-22)20-12-5-2-6-13-20/h1-6,9-10,12-13,21H,7-8,11,14-18H2
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n/an/a 2.20E+3n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
GABA receptor gamma-1 subunit


(Rattus norvegicus)
BDBM50055953
PNG
(1-[(3R,5R,10S,13S,17S)-3-Hydroxy-3-(2-hydroxy-phen...)
Show SMILES CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@](O)(CC[C@]4(C)[C@H]3CC[C@]12C)C#Cc1ccccc1O
Show InChI InChI=1S/C29H38O3/c1-19(30)23-10-11-24-22-9-8-21-18-29(32,15-12-20-6-4-5-7-26(20)31)17-16-27(21,2)25(22)13-14-28(23,24)3/h4-7,21-25,31-32H,8-11,13-14,16-18H2,1-3H3/t21-,22+,23-,24+,25+,27+,28-,29-/m1/s1
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n/an/a 5.10E+3n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of [35S]-TBPS binding to Gamma-aminobutyric acid A receptor in rat brain cortical membranes in the presence of 5 uM GABA (low aff...


J Med Chem 40: 73-84 (1997)


Article DOI: 10.1021/jm9605344
BindingDB Entry DOI: 10.7270/Q2CN731X
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50085927
PNG
(4-[1-(2-Hydroxy-4-phenyl-butyl)-piperidin-4-yl]-ph...)
Show SMILES OC(CCc1ccccc1)CN1CCC(CC1)c1ccc(O)cc1
Show InChI InChI=1S/C21H27NO2/c23-20-10-7-18(8-11-20)19-12-14-22(15-13-19)16-21(24)9-6-17-4-2-1-3-5-17/h1-5,7-8,10-11,19,21,23-24H,6,9,12-16H2
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n/an/a 5.90E+3n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-raclopride binding at Dopamine receptor D2 in rat brain membranes.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50085922
PNG
(4-(4-Hydroxy-phenyl)-1-(4-phenyl-butyl)-piperidin-...)
Show SMILES Oc1ccc(cc1)C1(O)CCN(CCCCc2ccccc2)CC1
Show InChI InChI=1S/C21H27NO2/c23-20-11-9-19(10-12-20)21(24)13-16-22(17-14-21)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,23-24H,4-5,8,13-17H2
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n/an/a 2.20E+4n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-raclopride binding at Dopamine receptor D2 in rat brain membranes.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50085933
PNG
(4-[1-(5-Phenyl-pentyl)-pyrrolidin-3-yl]-phenol | C...)
Show SMILES Oc1ccc(cc1)C1CCN(CCCCCc2ccccc2)C1
Show InChI InChI=1S/C21H27NO/c23-21-12-10-19(11-13-21)20-14-16-22(17-20)15-6-2-5-9-18-7-3-1-4-8-18/h1,3-4,7-8,10-13,20,23H,2,5-6,9,14-17H2
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n/an/a 4.10E+4n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369790
PNG
(CHEMBL1203914)
Show SMILES Oc1ccc(CCCCN2CCC(CC2)c2ccccc2)cc1
Show InChI InChI=1S/C21H27NO/c23-21-11-9-18(10-12-21)6-4-5-15-22-16-13-20(14-17-22)19-7-2-1-3-8-19/h1-3,7-12,20,23H,4-6,13-17H2
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n/an/a 4.30E+4n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369782
PNG
(CHEMBL1203909)
Show SMILES Oc1ccc(cc1)C1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C20H25NO/c22-20-10-8-18(9-11-20)19-12-15-21(16-13-19)14-4-7-17-5-2-1-3-6-17/h1-3,5-6,8-11,19,22H,4,7,12-16H2
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n/an/a 5.10E+4n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50085923
PNG
(4-[1-(4-Phenyl-butyl)-pyrrolidin-3-yl]-phenol | CH...)
Show SMILES Oc1ccc(cc1)C1CCN(CCCCc2ccccc2)C1
Show InChI InChI=1S/C20H25NO/c22-20-11-9-18(10-12-20)19-13-15-21(16-19)14-5-4-8-17-6-2-1-3-7-17/h1-3,6-7,9-12,19,22H,4-5,8,13-16H2
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n/an/a 5.20E+4n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369786
PNG
(CHEMBL1201889)
Show SMILES Oc1ccc(cc1)C1CCN(CCOCc2ccccc2)CC1
Show InChI InChI=1S/C20H25NO2/c22-20-8-6-18(7-9-20)19-10-12-21(13-11-19)14-15-23-16-17-4-2-1-3-5-17/h1-9,19,22H,10-16H2
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n/an/a 5.90E+4n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369788
PNG
(CHEMBL1202294)
Show SMILES CCCCN1CCC(CC1)c1ccc(O)cc1
Show InChI InChI=1S/C15H23NO/c1-2-3-10-16-11-8-14(9-12-16)13-4-6-15(17)7-5-13/h4-7,14,17H,2-3,8-12H2,1H3
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n/an/a 6.10E+4n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50085922
PNG
(4-(4-Hydroxy-phenyl)-1-(4-phenyl-butyl)-piperidin-...)
Show SMILES Oc1ccc(cc1)C1(O)CCN(CCCCc2ccccc2)CC1
Show InChI InChI=1S/C21H27NO2/c23-20-11-9-19(10-12-20)21(24)13-16-22(17-14-21)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,23-24H,4-5,8,13-17H2
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n/an/a 6.20E+4n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50085929
PNG
(4-(4-Hydroxy-phenyl)-1-(2-hydroxy-4-phenyl-butyl)-...)
Show SMILES OC(CCc1ccccc1)CN1CCC(O)(CC1)c1ccc(O)cc1
Show InChI InChI=1S/C21H27NO3/c23-19-10-7-18(8-11-19)21(25)12-14-22(15-13-21)16-20(24)9-6-17-4-2-1-3-5-17/h1-5,7-8,10-11,20,23-25H,6,9,12-16H2
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n/an/a 9.30E+4n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50085921
PNG
(4-[1-(3-Phenyl-propyl)-piperidin-4-ylmethyl]-pheno...)
Show SMILES Oc1ccc(CC2CCN(CCCc3ccccc3)CC2)cc1
Show InChI InChI=1S/C21H27NO/c23-21-10-8-19(9-11-21)17-20-12-15-22(16-13-20)14-4-7-18-5-2-1-3-6-18/h1-3,5-6,8-11,20,23H,4,7,12-17H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50085923
PNG
(4-[1-(4-Phenyl-butyl)-pyrrolidin-3-yl]-phenol | CH...)
Show SMILES Oc1ccc(cc1)C1CCN(CCCCc2ccccc2)C1
Show InChI InChI=1S/C20H25NO/c22-20-11-9-18(10-12-20)19-13-15-21(16-19)14-5-4-8-17-6-2-1-3-7-17/h1-3,6-7,9-12,19,22H,4-5,8,13-16H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2C) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50085925
PNG
(4-[1-(4-Phenyl-but-3-ynyl)-piperidin-4-ylmethyl]-p...)
Show SMILES Oc1ccc(CC2CCN(CCC#Cc3ccccc3)CC2)cc1
Show InChI InChI=1S/C22H25NO/c24-22-11-9-20(10-12-22)18-21-13-16-23(17-14-21)15-5-4-8-19-6-2-1-3-7-19/h1-3,6-7,9-12,21,24H,5,13-18H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369784
PNG
(CHEMBL1202295)
Show SMILES Oc1ccc(CC2CCN(CCCCc3ccccc3)CC2)cc1
Show InChI InChI=1S/C22H29NO/c24-22-11-9-20(10-12-22)18-21-13-16-23(17-14-21)15-5-4-8-19-6-2-1-3-7-19/h1-3,6-7,9-12,21,24H,4-5,8,13-18H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50007400
PNG
(4-Phenyl-1-(4-phenyl-butyl)-piperidine | 4-Phenyl-...)
Show SMILES C(CCc1ccccc1)CN1CCC(CC1)c1ccccc1
Show InChI InChI=1S/C21H27N/c1-3-9-19(10-4-1)11-7-8-16-22-17-14-21(15-18-22)20-12-5-2-6-13-20/h1-6,9-10,12-13,21H,7-8,11,14-18H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50085930
PNG
(4-[1-(3-Phenyl-prop-2-ynyl)-piperidin-4-ylmethyl]-...)
Show SMILES Oc1ccc(CC2CCN(CC#Cc3ccccc3)CC2)cc1
Show InChI InChI=1S/C21H23NO/c23-21-10-8-19(9-11-21)17-20-12-15-22(16-13-20)14-4-7-18-5-2-1-3-6-18/h1-3,5-6,8-11,20,23H,12-17H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50085929
PNG
(4-(4-Hydroxy-phenyl)-1-(2-hydroxy-4-phenyl-butyl)-...)
Show SMILES OC(CCc1ccccc1)CN1CCC(O)(CC1)c1ccc(O)cc1
Show InChI InChI=1S/C21H27NO3/c23-19-10-7-18(8-11-19)21(25)12-14-22(15-13-21)16-20(24)9-6-17-4-2-1-3-5-17/h1-5,7-8,10-11,20,23-25H,6,9,12-16H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2C) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369787
PNG
(CHEMBL1203901)
Show SMILES Oc1ccc(cc1)C1CCN(CCCCCc2ccccc2)CC1
Show InChI InChI=1S/C22H29NO/c24-22-12-10-20(11-13-22)21-14-17-23(18-15-21)16-6-2-5-9-19-7-3-1-4-8-19/h1,3-4,7-8,10-13,21,24H,2,5-6,9,14-18H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50085925
PNG
(4-[1-(4-Phenyl-but-3-ynyl)-piperidin-4-ylmethyl]-p...)
Show SMILES Oc1ccc(CC2CCN(CCC#Cc3ccccc3)CC2)cc1
Show InChI InChI=1S/C22H25NO/c24-22-11-9-20(10-12-22)18-21-13-16-23(17-14-21)15-5-4-8-19-6-2-1-3-7-19/h1-3,6-7,9-12,21,24H,5,13-18H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2C) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50085922
PNG
(4-(4-Hydroxy-phenyl)-1-(4-phenyl-butyl)-piperidin-...)
Show SMILES Oc1ccc(cc1)C1(O)CCN(CCCCc2ccccc2)CC1
Show InChI InChI=1S/C21H27NO2/c23-20-11-9-19(10-12-20)21(24)13-16-22(17-14-21)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,23-24H,4-5,8,13-17H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2C) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50085927
PNG
(4-[1-(2-Hydroxy-4-phenyl-butyl)-piperidin-4-yl]-ph...)
Show SMILES OC(CCc1ccccc1)CN1CCC(CC1)c1ccc(O)cc1
Show InChI InChI=1S/C21H27NO2/c23-20-10-7-18(8-11-20)19-12-14-22(15-13-19)16-21(24)9-6-17-4-2-1-3-5-17/h1-5,7-8,10-11,19,21,23-24H,6,9,12-16H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50369784
PNG
(CHEMBL1202295)
Show SMILES Oc1ccc(CC2CCN(CCCCc3ccccc3)CC2)cc1
Show InChI InChI=1S/C22H29NO/c24-22-11-9-20(10-12-22)18-21-13-16-23(17-14-21)15-5-4-8-19-6-2-1-3-7-19/h1-3,6-7,9-12,21,24H,4-5,8,13-18H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2C) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50369782
PNG
(CHEMBL1203909)
Show SMILES Oc1ccc(cc1)C1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C20H25NO/c22-20-10-8-18(9-11-20)19-12-15-21(16-13-19)14-4-7-17-5-2-1-3-6-17/h1-3,5-6,8-11,19,22H,4,7,12-16H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2C) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369788
PNG
(CHEMBL1202294)
Show SMILES CCCCN1CCC(CC1)c1ccc(O)cc1
Show InChI InChI=1S/C15H23NO/c1-2-3-10-16-11-8-14(9-12-16)13-4-6-15(17)7-5-13/h4-7,14,17H,2-3,8-12H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50369789
PNG
(CHEMBL1203894)
Show SMILES COc1ccc(cc1)C1CCN(CCCCc2ccccc2)CC1
Show InChI InChI=1S/C22H29NO/c1-24-22-12-10-20(11-13-22)21-14-17-23(18-15-21)16-6-5-9-19-7-3-2-4-8-19/h2-4,7-8,10-13,21H,5-6,9,14-18H2,1H3
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CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50369790
PNG
(CHEMBL1203914)
Show SMILES Oc1ccc(CCCCN2CCC(CC2)c2ccccc2)cc1
Show InChI InChI=1S/C21H27NO/c23-21-11-9-18(10-12-21)6-4-5-15-22-16-13-20(14-17-22)19-7-2-1-3-8-19/h1-3,7-12,20,23H,4-6,13-17H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2C) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50007400
PNG
(4-Phenyl-1-(4-phenyl-butyl)-piperidine | 4-Phenyl-...)
Show SMILES C(CCc1ccccc1)CN1CCC(CC1)c1ccccc1
Show InChI InChI=1S/C21H27N/c1-3-9-19(10-4-1)11-7-8-16-22-17-14-21(15-18-22)20-12-5-2-6-13-20/h1-6,9-10,12-13,21H,7-8,11,14-18H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2C) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50369789
PNG
(CHEMBL1203894)
Show SMILES COc1ccc(cc1)C1CCN(CCCCc2ccccc2)CC1
Show InChI InChI=1S/C22H29NO/c1-24-22-12-10-20(11-13-22)21-14-17-23(18-15-21)16-6-5-9-19-7-3-2-4-8-19/h2-4,7-8,10-13,21H,5-6,9,14-18H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2C) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50085921
PNG
(4-[1-(3-Phenyl-propyl)-piperidin-4-ylmethyl]-pheno...)
Show SMILES Oc1ccc(CC2CCN(CCCc3ccccc3)CC2)cc1
Show InChI InChI=1S/C21H27NO/c23-21-10-8-19(9-11-21)17-20-12-15-22(16-13-20)14-4-7-18-5-2-1-3-6-18/h1-3,5-6,8-11,20,23H,4,7,12-17H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2C) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50369786
PNG
(CHEMBL1201889)
Show SMILES Oc1ccc(cc1)C1CCN(CCOCc2ccccc2)CC1
Show InChI InChI=1S/C20H25NO2/c22-20-8-6-18(7-9-20)19-10-12-21(13-11-19)14-15-23-16-17-4-2-1-3-5-17/h1-9,19,22H,10-16H2
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CoCensys, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2C) Receptor subtype.


J Med Chem 43: 984-94 (2000)


Article DOI: 10.1021/jm990428c
BindingDB Entry DOI: 10.7270/Q20G3KVT
More data for this
Ligand-Target Pair
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