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Compile Data Set for Download or QSAR

Found 43 hits with Last Name = 'adamski' and Initial = 'sw'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adrenergic receptor beta


(Rattus norvegicus (Rat))
BDBM50222540
PNG
(CHEMBL19679)
Show SMILES CC(Oc1ccc(C)c(C)c1)C(O)CNC(C)(C)C
Show InChI InChI=1S/C16H27NO2/c1-11-7-8-14(9-12(11)2)19-13(3)15(18)10-17-16(4,5)6/h7-9,13,15,17-18H,10H2,1-6H3
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n/an/an/a 200n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against Beta adrenergic receptor in C6-2B astrocytoma cells, using [125I]-iodohydroxybenzylpindolol-benzylpindolol([125I]-HYP)


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM50222774
PNG
(CHEMBL19757)
Show SMILES CCc1ccc(OCC(O)C(C)NC(C)C)cc1
Show InChI InChI=1S/C15H25NO2/c1-5-13-6-8-14(9-7-13)18-10-15(17)12(4)16-11(2)3/h6-9,11-12,15-17H,5,10H2,1-4H3
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n/an/an/an/a 4.42E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal strips


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM50222540
PNG
(CHEMBL19679)
Show SMILES CC(Oc1ccc(C)c(C)c1)C(O)CNC(C)(C)C
Show InChI InChI=1S/C16H27NO2/c1-11-7-8-14(9-12(11)2)19-13(3)15(18)10-17-16(4,5)6/h7-9,13,15,17-18H,10H2,1-6H3
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n/an/an/an/a 1.07E+4n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal strips


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50222721
PNG
(CHEMBL19625)
Show SMILES CC(NC(C)(C)C)C(O)COc1ccc(C)c(C)c1
Show InChI InChI=1S/C16H27NO2/c1-11-7-8-14(9-12(11)2)19-10-15(18)13(3)17-16(4,5)6/h7-9,13,15,17-18H,10H2,1-6H3
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n/an/an/an/a 206n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparations


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Adrenergic receptor beta


(Rattus norvegicus (Rat))
BDBM50222722
PNG
(CHEMBL20234)
Show SMILES CC(C)NCC(O)C(C)Oc1ccc2ccccc2c1
Show InChI InChI=1S/C17H23NO2/c1-12(2)18-11-17(19)13(3)20-16-9-8-14-6-4-5-7-15(14)10-16/h4-10,12-13,17-19H,11H2,1-3H3
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n/an/an/a 40n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against Beta adrenergic receptor in C6-2B astrocytoma cells, using [125I]-iodohydroxybenzylpindolol-benzylpindolol([125I]-HYP)


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Adrenergic receptor beta


(Rattus norvegicus (Rat))
BDBM50222723
PNG
(CHEMBL19422)
Show SMILES CC(Oc1ccccc1CC=C)C(O)CNC(C)(C)C
Show InChI InChI=1S/C17H27NO2/c1-6-9-14-10-7-8-11-16(14)20-13(2)15(19)12-18-17(3,4)5/h6-8,10-11,13,15,18-19H,1,9,12H2,2-5H3
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n/an/an/a 15n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against Beta adrenergic receptor in C6-2B astrocytoma cells, using [125I]-iodohydroxybenzylpindolol-benzylpindolol([125I]-HYP)


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM50222723
PNG
(CHEMBL19422)
Show SMILES CC(Oc1ccccc1CC=C)C(O)CNC(C)(C)C
Show InChI InChI=1S/C17H27NO2/c1-6-9-14-10-7-8-11-16(14)20-13(2)15(19)12-18-17(3,4)5/h6-8,10-11,13,15,18-19H,1,9,12H2,2-5H3
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n/an/an/an/a 4.38E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal strips


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Adrenergic receptor beta


(Rattus norvegicus (Rat))
BDBM50222724
PNG
(CHEMBL19669)
Show SMILES CCc1ccc(OC(C)C(O)CNC(C)(C)C)cc1
Show InChI InChI=1S/C16H27NO2/c1-6-13-7-9-14(10-8-13)19-12(2)15(18)11-17-16(3,4)5/h7-10,12,15,17-18H,6,11H2,1-5H3
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n/an/an/a 2.00E+3n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against Beta adrenergic receptor in C6-2B astrocytoma cells, using [125I]-iodohydroxybenzylpindolol-benzylpindolol([125I]-HYP)


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50222725
PNG
(CHEMBL415999)
Show SMILES CCc1ccc(OCC(O)C(C)NC(C)(C)C)cc1
Show InChI InChI=1S/C16H27NO2/c1-6-13-7-9-14(10-8-13)19-11-15(18)12(2)17-16(3,4)5/h7-10,12,15,17-18H,6,11H2,1-5H3
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n/an/an/an/a 207n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparations


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM50222768
PNG
(CHEMBL19680)
Show SMILES CCc1ccc(OC(C)C(O)CNC(C)C)cc1
Show InChI InChI=1S/C15H25NO2/c1-5-13-6-8-14(9-7-13)18-12(4)15(17)10-16-11(2)3/h6-9,11-12,15-17H,5,10H2,1-4H3
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n/an/an/an/a 1.96E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal strips


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM50222769
PNG
(CHEMBL19809)
Show SMILES CC(Oc1ccccc1)C(O)CNC(C)(C)C
Show InChI InChI=1S/C14H23NO2/c1-11(13(16)10-15-14(2,3)4)17-12-8-6-5-7-9-12/h5-9,11,13,15-16H,10H2,1-4H3
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n/an/an/an/a 1.30E+4n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal strips


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50222540
PNG
(CHEMBL19679)
Show SMILES CC(Oc1ccc(C)c(C)c1)C(O)CNC(C)(C)C
Show InChI InChI=1S/C16H27NO2/c1-11-7-8-14(9-12(11)2)19-13(3)15(18)10-17-16(4,5)6/h7-9,13,15,17-18H,10H2,1-6H3
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n/an/an/an/a 490n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparations


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50222770
PNG
(CHEMBL19593)
Show SMILES CC(C)NCC(O)C(C)Oc1ccc(C)c(C)c1
Show InChI InChI=1S/C15H25NO2/c1-10(2)16-9-15(17)13(5)18-14-7-6-11(3)12(4)8-14/h6-8,10,13,15-17H,9H2,1-5H3
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n/an/an/an/a 676n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparations


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM50222770
PNG
(CHEMBL19593)
Show SMILES CC(C)NCC(O)C(C)Oc1ccc(C)c(C)c1
Show InChI InChI=1S/C15H25NO2/c1-10(2)16-9-15(17)13(5)18-14-7-6-11(3)12(4)8-14/h6-8,10,13,15-17H,9H2,1-5H3
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n/an/an/an/a 4.06E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal strips


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50222772
PNG
(CHEMBL281994)
Show SMILES CC(NC(C)(C)C)C(O)COc1ccccc1
Show InChI InChI=1S/C14H23NO2/c1-11(15-14(2,3)4)13(16)10-17-12-8-6-5-7-9-12/h5-9,11,13,15-16H,10H2,1-4H3
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n/an/an/an/a 523n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparations


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM50222725
PNG
(CHEMBL415999)
Show SMILES CCc1ccc(OCC(O)C(C)NC(C)(C)C)cc1
Show InChI InChI=1S/C16H27NO2/c1-6-13-7-9-14(10-8-13)19-11-15(18)12(2)17-16(3,4)5/h7-10,12,15,17-18H,6,11H2,1-5H3
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n/an/an/an/a 2.13E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal strips


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50222768
PNG
(CHEMBL19680)
Show SMILES CCc1ccc(OC(C)C(O)CNC(C)C)cc1
Show InChI InChI=1S/C15H25NO2/c1-5-13-6-8-14(9-7-13)18-12(4)15(17)10-16-11(2)3/h6-9,11-12,15-17H,5,10H2,1-4H3
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n/an/an/an/a 505n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparations


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM50222773
PNG
(CHEMBL20909)
Show SMILES CC(C)NCC(O)C(C)Oc1ccccc1CC=C
Show InChI InChI=1S/C16H25NO2/c1-5-8-14-9-6-7-10-16(14)19-13(4)15(18)11-17-12(2)3/h5-7,9-10,12-13,15,17-18H,1,8,11H2,2-4H3
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n/an/an/an/a 6.18E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal strips


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50222774
PNG
(CHEMBL19757)
Show SMILES CCc1ccc(OCC(O)C(C)NC(C)C)cc1
Show InChI InChI=1S/C15H25NO2/c1-5-13-6-8-14(9-7-13)18-10-15(17)12(4)16-11(2)3/h6-9,11-12,15-17H,5,10H2,1-4H3
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n/an/an/an/a 403n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparations


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50222775
PNG
(CHEMBL19591)
Show SMILES CC(C)NCC(O)C(C)Oc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C13H19Cl2NO2/c1-8(2)16-7-13(17)9(3)18-10-4-5-11(14)12(15)6-10/h4-6,8-9,13,16-17H,7H2,1-3H3
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n/an/an/an/a 259n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparations


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM50222772
PNG
(CHEMBL281994)
Show SMILES CC(NC(C)(C)C)C(O)COc1ccccc1
Show InChI InChI=1S/C14H23NO2/c1-11(15-14(2,3)4)13(16)10-17-12-8-6-5-7-9-12/h5-9,11,13,15-16H,10H2,1-4H3
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n/an/an/an/a 4.41E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal strips


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Adrenergic receptor beta


(Rattus norvegicus (Rat))
BDBM50222773
PNG
(CHEMBL20909)
Show SMILES CC(C)NCC(O)C(C)Oc1ccccc1CC=C
Show InChI InChI=1S/C16H25NO2/c1-5-8-14-9-6-7-10-16(14)19-13(4)15(18)11-17-12(2)3/h5-7,9-10,12-13,15,17-18H,1,8,11H2,2-4H3
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n/an/an/a 50n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against Beta adrenergic receptor in C6-2B astrocytoma cells, using [125I]-iodohydroxybenzylpindolol-benzylpindolol([125I]-HYP)


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM25761
PNG
(Anapriline | Avlocardyl | CHEMBL27 | PROPANOLOL(-)...)
Show SMILES CC(C)NCC(O)COc1cccc2ccccc12
Show InChI InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3
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n/an/an/an/a 1.02E+4n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal strips


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM50222776
PNG
(CHEMBL19770)
Show SMILES CC(Oc1ccc2ccccc2c1)C(O)CNC(C)(C)C
Show InChI InChI=1S/C18H25NO2/c1-13(17(20)12-19-18(2,3)4)21-16-10-9-14-7-5-6-8-15(14)11-16/h5-11,13,17,19-20H,12H2,1-4H3
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n/an/an/an/a 2.59E+4n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal strips


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM50223404
PNG
(CHEMBL277459)
Show SMILES CC(C)NC(C)C(O)COc1ccc(C)c(C)c1
Show InChI InChI=1S/C15H25NO2/c1-10(2)16-13(5)15(17)9-18-14-7-6-11(3)12(4)8-14/h6-8,10,13,15-17H,9H2,1-5H3
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n/an/an/an/a 2.96E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal strips


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Adrenergic receptor beta


(Rattus norvegicus (Rat))
BDBM50246936
PNG
((-)-(S)-Propranolol | 1-(ISOPROPYLAMINO)-3-(1-NAPH...)
Show SMILES CC(C)NC[C@H](O)COc1cccc2ccccc12
Show InChI InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3/t14-/m0/s1
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n/an/an/a 0.700n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against Beta adrenergic receptor in C6-2B astrocytoma cells, using [125I]-iodohydroxybenzylpindolol-benzylpindolol([125I]-HYP)


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50222724
PNG
(CHEMBL19669)
Show SMILES CCc1ccc(OC(C)C(O)CNC(C)(C)C)cc1
Show InChI InChI=1S/C16H27NO2/c1-6-13-7-9-14(10-8-13)19-12(2)15(18)11-17-16(3,4)5/h7-10,12,15,17-18H,6,11H2,1-5H3
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n/an/an/an/a 199n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparations


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50222722
PNG
(CHEMBL20234)
Show SMILES CC(C)NCC(O)C(C)Oc1ccc2ccccc2c1
Show InChI InChI=1S/C17H23NO2/c1-12(2)18-11-17(19)13(3)20-16-9-8-14-6-4-5-7-15(14)10-16/h4-10,12-13,17-19H,11H2,1-3H3
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n/an/an/an/a 2.28E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparations


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50222723
PNG
(CHEMBL19422)
Show SMILES CC(Oc1ccccc1CC=C)C(O)CNC(C)(C)C
Show InChI InChI=1S/C17H27NO2/c1-6-9-14-10-7-8-11-16(14)20-13(2)15(19)12-18-17(3,4)5/h6-8,10-11,13,15,18-19H,1,9,12H2,2-5H3
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n/an/an/an/a 616n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparations


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Adrenergic receptor beta


(Rattus norvegicus (Rat))
BDBM50222776
PNG
(CHEMBL19770)
Show SMILES CC(Oc1ccc2ccccc2c1)C(O)CNC(C)(C)C
Show InChI InChI=1S/C18H25NO2/c1-13(17(20)12-19-18(2,3)4)21-16-10-9-14-7-5-6-8-15(14)11-16/h5-11,13,17,19-20H,12H2,1-4H3
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n/an/an/a 5n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against Beta adrenergic receptor in C6-2B astrocytoma cells, using [125I]-iodohydroxybenzylpindolol-benzylpindolol([125I]-HYP)


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50222776
PNG
(CHEMBL19770)
Show SMILES CC(Oc1ccc2ccccc2c1)C(O)CNC(C)(C)C
Show InChI InChI=1S/C18H25NO2/c1-13(17(20)12-19-18(2,3)4)21-16-10-9-14-7-5-6-8-15(14)11-16/h5-11,13,17,19-20H,12H2,1-4H3
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n/an/an/an/a 1.82E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparations


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50222769
PNG
(CHEMBL19809)
Show SMILES CC(Oc1ccccc1)C(O)CNC(C)(C)C
Show InChI InChI=1S/C14H23NO2/c1-11(13(16)10-15-14(2,3)4)17-12-8-6-5-7-9-12/h5-9,11,13,15-16H,10H2,1-4H3
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n/an/an/an/a 799n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparations


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50223404
PNG
(CHEMBL277459)
Show SMILES CC(C)NC(C)C(O)COc1ccc(C)c(C)c1
Show InChI InChI=1S/C15H25NO2/c1-10(2)16-13(5)15(17)9-18-14-7-6-11(3)12(4)8-14/h6-8,10,13,15-17H,9H2,1-5H3
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n/an/an/an/a 997n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparations


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Adrenergic receptor beta


(Rattus norvegicus (Rat))
BDBM50222775
PNG
(CHEMBL19591)
Show SMILES CC(C)NCC(O)C(C)Oc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C13H19Cl2NO2/c1-8(2)16-7-13(17)9(3)18-10-4-5-11(14)12(15)6-10/h4-6,8-9,13,16-17H,7H2,1-3H3
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n/an/an/a 500n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against Beta adrenergic receptor in C6-2B astrocytoma cells, using [125I]-iodohydroxybenzylpindolol-benzylpindolol([125I]-HYP)


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM50222721
PNG
(CHEMBL19625)
Show SMILES CC(NC(C)(C)C)C(O)COc1ccc(C)c(C)c1
Show InChI InChI=1S/C16H27NO2/c1-11-7-8-14(9-12(11)2)19-10-15(18)13(3)17-16(4,5)6/h7-9,13,15,17-18H,10H2,1-6H3
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n/an/an/an/a 1.77E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal strips


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Adrenergic receptor beta


(Rattus norvegicus (Rat))
BDBM50222770
PNG
(CHEMBL19593)
Show SMILES CC(C)NCC(O)C(C)Oc1ccc(C)c(C)c1
Show InChI InChI=1S/C15H25NO2/c1-10(2)16-9-15(17)13(5)18-14-7-6-11(3)12(4)8-14/h6-8,10,13,15-17H,9H2,1-5H3
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n/an/an/a 200n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against Beta adrenergic receptor in C6-2B astrocytoma cells, using [125I]-iodohydroxybenzylpindolol-benzylpindolol([125I]-HYP)


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Adrenergic receptor beta


(Rattus norvegicus (Rat))
BDBM50222768
PNG
(CHEMBL19680)
Show SMILES CCc1ccc(OC(C)C(O)CNC(C)C)cc1
Show InChI InChI=1S/C15H25NO2/c1-5-13-6-8-14(9-7-13)18-12(4)15(17)10-16-11(2)3/h6-9,11-12,15-17H,5,10H2,1-4H3
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n/an/an/a 2.00E+3n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against Beta adrenergic receptor in C6-2B astrocytoma cells, using [125I]-iodohydroxybenzylpindolol-benzylpindolol([125I]-HYP)


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM50222775
PNG
(CHEMBL19591)
Show SMILES CC(C)NCC(O)C(C)Oc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C13H19Cl2NO2/c1-8(2)16-7-13(17)9(3)18-10-4-5-11(14)12(15)6-10/h4-6,8-9,13,16-17H,7H2,1-3H3
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n/an/an/an/a 4.12E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal strips


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM50222724
PNG
(CHEMBL19669)
Show SMILES CCc1ccc(OC(C)C(O)CNC(C)(C)C)cc1
Show InChI InChI=1S/C16H27NO2/c1-6-13-7-9-14(10-8-13)19-12(2)15(18)11-17-16(3,4)5/h7-10,12,15,17-18H,6,11H2,1-5H3
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n/an/an/an/a 1.92E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal strips


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Adrenergic receptor beta


(Rattus norvegicus (Rat))
BDBM50222769
PNG
(CHEMBL19809)
Show SMILES CC(Oc1ccccc1)C(O)CNC(C)(C)C
Show InChI InChI=1S/C14H23NO2/c1-11(13(16)10-15-14(2,3)4)17-12-8-6-5-7-9-12/h5-9,11,13,15-16H,10H2,1-4H3
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n/an/an/a 300n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against Beta adrenergic receptor in C6-2B astrocytoma cells, using [125I]-iodohydroxybenzylpindolol-benzylpindolol([125I]-HYP)


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM50222773
PNG
(CHEMBL20909)
Show SMILES CC(C)NCC(O)C(C)Oc1ccccc1CC=C
Show InChI InChI=1S/C16H25NO2/c1-5-8-14-9-6-7-10-16(14)19-13(4)15(18)11-17-12(2)3/h5-7,9-10,12-13,15,17-18H,1,8,11H2,2-4H3
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n/an/an/an/a 737n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparations


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(GUINEA PIG)
BDBM50222722
PNG
(CHEMBL20234)
Show SMILES CC(C)NCC(O)C(C)Oc1ccc2ccccc2c1
Show InChI InChI=1S/C17H23NO2/c1-12(2)18-11-17(19)13(3)20-16-9-8-14-6-4-5-7-15(14)10-16/h4-10,12-13,17-19H,11H2,1-3H3
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n/an/an/an/a 1.51E+4n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal strips


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(GUINEA PIG)
BDBM25761
PNG
(Anapriline | Avlocardyl | CHEMBL27 | PROPANOLOL(-)...)
Show SMILES CC(C)NCC(O)COc1cccc2ccccc12
Show InChI InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3
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n/an/an/an/a 1.91E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparations


J Med Chem 24: 1211-4 (1981)


Article DOI: 10.1021/jm00142a017
More data for this
Ligand-Target Pair