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Compile Data Set for Download or QSAR

Found 68 hits with Last Name = 'ahn' and Initial = 'bn'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50263750
PNG
(2-ethoxy-3-(4-(2-(4-(2-methoxyphenyl)-5,6-dihydrop...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccccc2OC)cc1)C(O)=O
Show InChI InChI=1S/C25H31NO5/c1-3-30-24(25(27)28)18-19-8-10-21(11-9-19)31-17-16-26-14-12-20(13-15-26)22-6-4-5-7-23(22)29-2/h4-12,24H,3,13-18H2,1-2H3,(H,27,28)
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n/an/an/an/a 3.93E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50263796
PNG
(2-ethoxy-3-(4-(2-(4-(4-ethylphenyl)-5,6-dihydropyr...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccc(CC)cc2)cc1)C(O)=O
Show InChI InChI=1S/C26H33NO4/c1-3-20-5-9-22(10-6-20)23-13-15-27(16-14-23)17-18-31-24-11-7-21(8-12-24)19-25(26(28)29)30-4-2/h5-13,25H,3-4,14-19H2,1-2H3,(H,28,29)
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n/an/an/an/a 689n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50263797
PNG
(2-ethoxy-3-(4-(2-(4-(4-propylphenyl)-5,6-dihydropy...)
Show SMILES CCCc1ccc(cc1)C1=CCN(CCOc2ccc(CC(OCC)C(O)=O)cc2)CC1
Show InChI InChI=1S/C27H35NO4/c1-3-5-21-6-10-23(11-7-21)24-14-16-28(17-15-24)18-19-32-25-12-8-22(9-13-25)20-26(27(29)30)31-4-2/h6-14,26H,3-5,15-20H2,1-2H3,(H,29,30)
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n/an/an/an/a 174n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50263798
PNG
(3-(4-(2-(4-(2,3-dichlorophenyl)-5,6-dihydropyridin...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2cccc(Cl)c2Cl)cc1)C(O)=O
Show InChI InChI=1S/C24H27Cl2NO4/c1-2-30-22(24(28)29)16-17-6-8-19(9-7-17)31-15-14-27-12-10-18(11-13-27)20-4-3-5-21(25)23(20)26/h3-10,22H,2,11-16H2,1H3,(H,28,29)
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n/an/an/an/a 661n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50263799
PNG
(3-(4-(2-(4-(2,4-dichlorophenyl)-5,6-dihydropyridin...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccc(Cl)cc2Cl)cc1)C(O)=O
Show InChI InChI=1S/C24H27Cl2NO4/c1-2-30-23(24(28)29)15-17-3-6-20(7-4-17)31-14-13-27-11-9-18(10-12-27)21-8-5-19(25)16-22(21)26/h3-9,16,23H,2,10-15H2,1H3,(H,28,29)
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n/an/an/an/a 706n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50263847
PNG
(3-(4-(2-(4-(2,5-dichlorophenyl)-5,6-dihydropyridin...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2cc(Cl)ccc2Cl)cc1)C(O)=O
Show InChI InChI=1S/C24H27Cl2NO4/c1-2-30-23(24(28)29)15-17-3-6-20(7-4-17)31-14-13-27-11-9-18(10-12-27)21-16-19(25)5-8-22(21)26/h3-9,16,23H,2,10-15H2,1H3,(H,28,29)
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n/an/an/an/a 1.44E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50263848
PNG
(3-(4-(2-(4-(3,4-dichlorophenyl)-5,6-dihydropyridin...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccc(Cl)c(Cl)c2)cc1)C(O)=O
Show InChI InChI=1S/C24H27Cl2NO4/c1-2-30-23(24(28)29)15-17-3-6-20(7-4-17)31-14-13-27-11-9-18(10-12-27)19-5-8-21(25)22(26)16-19/h3-9,16,23H,2,10-15H2,1H3,(H,28,29)
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n/an/an/an/a 670n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50263849
PNG
((S)-3-(4-(2-(4-(3,4-dichlorophenyl)-5,6-dihydropyr...)
Show SMILES CCO[C@@H](Cc1ccc(OCCN2CCC(=CC2)c2ccc(Cl)c(Cl)c2)cc1)C(O)=O
Show InChI InChI=1S/C24H27Cl2NO4/c1-2-30-23(24(28)29)15-17-3-6-20(7-4-17)31-14-13-27-11-9-18(10-12-27)19-5-8-21(25)22(26)16-19/h3-9,16,23H,2,10-15H2,1H3,(H,28,29)/t23-/m0/s1
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n/an/an/an/a 862n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50263850
PNG
(3-(4-(2-(4-(3,5-dichlorophenyl)-5,6-dihydropyridin...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2cc(Cl)cc(Cl)c2)cc1)C(O)=O
Show InChI InChI=1S/C24H27Cl2NO4/c1-2-30-23(24(28)29)13-17-3-5-22(6-4-17)31-12-11-27-9-7-18(8-10-27)19-14-20(25)16-21(26)15-19/h3-7,14-16,23H,2,8-13H2,1H3,(H,28,29)
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n/an/an/an/a 1.42E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50263901
PNG
(2-ethoxy-3-(4-(2-(4-(pyridin-2-yl)-5,6-dihydropyri...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccccn2)cc1)C(O)=O
Show InChI InChI=1S/C23H28N2O4/c1-2-28-22(23(26)27)17-18-6-8-20(9-7-18)29-16-15-25-13-10-19(11-14-25)21-5-3-4-12-24-21/h3-10,12,22H,2,11,13-17H2,1H3,(H,26,27)
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n/an/an/an/a 2.30E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50263902
PNG
(2-ethoxy-3-(4-(2-(4-(thiophen-2-yl)-5,6-dihydropyr...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2cccs2)cc1)C(O)=O
Show InChI InChI=1S/C22H27NO4S/c1-2-26-20(22(24)25)16-17-5-7-19(8-6-17)27-14-13-23-11-9-18(10-12-23)21-4-3-15-28-21/h3-9,15,20H,2,10-14,16H2,1H3,(H,24,25)
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n/an/an/an/a 3.30E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50263903
PNG
(2-ethoxy-3-(4-(2-(4-(pyrazin-2-yl)-5,6-dihydropyri...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2cnccn2)cc1)C(O)=O
Show InChI InChI=1S/C22H27N3O4/c1-2-28-21(22(26)27)15-17-3-5-19(6-4-17)29-14-13-25-11-7-18(8-12-25)20-16-23-9-10-24-20/h3-7,9-10,16,21H,2,8,11-15H2,1H3,(H,26,27)
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n/an/an/an/a 1.26E+4n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50263904
PNG
(2-ethoxy-3-(4-(2-(4-(pyrimidin-2-yl)-5,6-dihydropy...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ncccn2)cc1)C(O)=O
Show InChI InChI=1S/C22H27N3O4/c1-2-28-20(22(26)27)16-17-4-6-19(7-5-17)29-15-14-25-12-8-18(9-13-25)21-23-10-3-11-24-21/h3-8,10-11,20H,2,9,12-16H2,1H3,(H,26,27)
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n/an/an/an/a 4.60E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50263905
PNG
(3-(4-(3-(4-(4-chlorophenyl)-5,6-dihydropyridin-1(2...)
Show SMILES CCOC(Cc1ccc(OCCCN2CCC(=CC2)c2ccc(Cl)cc2)cc1)C(O)=O
Show InChI InChI=1S/C25H30ClNO4/c1-2-30-24(25(28)29)18-19-4-10-23(11-5-19)31-17-3-14-27-15-12-21(13-16-27)20-6-8-22(26)9-7-20/h4-12,24H,2-3,13-18H2,1H3,(H,28,29)
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n/an/an/an/a 2.32E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50263953
PNG
(2-ethoxy-3-(4-(3-(4-(4-(trifluoromethyl)phenyl)-5,...)
Show SMILES CCOC(Cc1ccc(OCCCN2CCC(=CC2)c2ccc(cc2)C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C26H30F3NO4/c1-2-33-24(25(31)32)18-19-4-10-23(11-5-19)34-17-3-14-30-15-12-21(13-16-30)20-6-8-22(9-7-20)26(27,28)29/h4-12,24H,2-3,13-18H2,1H3,(H,31,32)
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n/an/an/an/a 504n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50263954
PNG
(3-(4-(3-(4-(3,4-dichlorophenyl)-5,6-dihydropyridin...)
Show SMILES CCOC(Cc1ccc(OCCCN2CCC(=CC2)c2ccc(Cl)c(Cl)c2)cc1)C(O)=O
Show InChI InChI=1S/C25H29Cl2NO4/c1-2-31-24(25(29)30)16-18-4-7-21(8-5-18)32-15-3-12-28-13-10-19(11-14-28)20-6-9-22(26)23(27)17-20/h4-10,17,24H,2-3,11-16H2,1H3,(H,29,30)
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n/an/an/an/a 728n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50263955
PNG
(2-(4-(2-(4-(4-chlorophenyl)-5,6-dihydropyridin-1(2...)
Show SMILES CCC(Cc1ccc(OCCN2CCC(=CC2)c2ccc(Cl)cc2)cc1)C(O)=O
Show InChI InChI=1S/C24H28ClNO3/c1-2-19(24(27)28)17-18-3-9-23(10-4-18)29-16-15-26-13-11-21(12-14-26)20-5-7-22(25)8-6-20/h3-11,19H,2,12-17H2,1H3,(H,27,28)
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n/an/an/an/a 5.29E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50263956
PNG
(3-(4-(2-(4-(4-chlorophenyl)-5,6-dihydropyridin-1(2...)
Show SMILES CC(Cc1ccc(OCCN2CCC(=CC2)c2ccc(Cl)cc2)cc1)(Oc1ccccc1)C(O)=O
Show InChI InChI=1S/C29H30ClNO4/c1-29(28(32)33,35-27-5-3-2-4-6-27)21-22-7-13-26(14-8-22)34-20-19-31-17-15-24(16-18-31)23-9-11-25(30)12-10-23/h2-15H,16-21H2,1H3,(H,32,33)
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n/an/an/an/a 4.88E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50264017
PNG
(2-(4-(2-(4-(4-chlorophenyl)-5,6-dihydropyridin-1(2...)
Show SMILES CC(C)(Oc1ccc(OCCN2CCC(=CC2)c2ccc(Cl)cc2)cc1)C(O)=O
Show InChI InChI=1S/C23H26ClNO4/c1-23(2,22(26)27)29-21-9-7-20(8-10-21)28-16-15-25-13-11-18(12-14-25)17-3-5-19(24)6-4-17/h3-11H,12-16H2,1-2H3,(H,26,27)
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n/an/an/an/a 2.28E+4n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50264018
PNG
(2-(3-(2-(4-(4-chlorophenyl)-5,6-dihydropyridin-1(2...)
Show SMILES CC(C)(Oc1cccc(OCCN2CCC(=CC2)c2ccc(Cl)cc2)c1)C(O)=O
Show InChI InChI=1S/C23H26ClNO4/c1-23(2,22(26)27)29-21-5-3-4-20(16-21)28-15-14-25-12-10-18(11-13-25)17-6-8-19(24)9-7-17/h3-10,16H,11-15H2,1-2H3,(H,26,27)
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n/an/an/an/a 1.88E+4n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM28681
PNG
(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Show SMILES CN(CCOc1ccc(Cc2sc(=O)[nH]c2O)cc1)c1ccccn1
Show InChI InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,22H,10-12H2,1H3,(H,20,23)
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n/an/an/an/a 3.46E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50150998
PNG
(((4-Methoxy-phenoxycarbonyl)-{4-[2-(5-methyl-2-phe...)
Show SMILES COc1ccc(OC(=O)N(CC(O)=O)Cc2ccc(OCCc3nc(oc3C)-c3ccccc3)cc2)cc1
Show InChI InChI=1S/C29H28N2O7/c1-20-26(30-28(37-20)22-6-4-3-5-7-22)16-17-36-24-10-8-21(9-11-24)18-31(19-27(32)33)29(34)38-25-14-12-23(35-2)13-15-25/h3-15H,16-19H2,1-2H3,(H,32,33)
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n/an/an/an/a 4.11E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM28798
PNG
((2S)-2-ethoxy-3-(4-{2-[4-(methanesulfonyloxy)pheny...)
Show SMILES CCO[C@@H](Cc1ccc(OCCc2ccc(OS(C)(=O)=O)cc2)cc1)C(O)=O
Show InChI InChI=1S/C20H24O7S/c1-3-25-19(20(21)22)14-16-6-8-17(9-7-16)26-13-12-15-4-10-18(11-5-15)27-28(2,23)24/h4-11,19H,3,12-14H2,1-2H3,(H,21,22)/t19-/m0/s1
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n/an/an/an/a 3.12E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263651
PNG
(2-ethoxy-3-(4-(2-(4-phenyl-5,6-dihydropyridin-1(2H...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccccc2)cc1)C(O)=O
Show InChI InChI=1S/C24H29NO4/c1-2-28-23(24(26)27)18-19-8-10-22(11-9-19)29-17-16-25-14-12-21(13-15-25)20-6-4-3-5-7-20/h3-12,23H,2,13-18H2,1H3,(H,26,27)
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n/an/an/an/a 5.98E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263652
PNG
(3-(4-(2-(4-(4-chlorophenyl)-5,6-dihydropyridin-1(2...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccc(Cl)cc2)cc1)C(O)=O
Show InChI InChI=1S/C24H28ClNO4/c1-2-29-23(24(27)28)17-18-3-9-22(10-4-18)30-16-15-26-13-11-20(12-14-26)19-5-7-21(25)8-6-19/h3-11,23H,2,12-17H2,1H3,(H,27,28)
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n/an/an/an/a 7.07E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263653
PNG
((S)-3-(4-(2-(4-(4-chlorophenyl)-5,6-dihydropyridin...)
Show SMILES CCO[C@@H](Cc1ccc(OCCN2CCC(=CC2)c2ccc(Cl)cc2)cc1)C(O)=O
Show InChI InChI=1S/C24H28ClNO4/c1-2-29-23(24(27)28)17-18-3-9-22(10-4-18)30-16-15-26-13-11-20(12-14-26)19-5-7-21(25)8-6-19/h3-11,23H,2,12-17H2,1H3,(H,27,28)/t23-/m0/s1
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n/an/an/an/a 1.73E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263654
PNG
(3-(4-(2-(4-(3-chlorophenyl)-5,6-dihydropyridin-1(2...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2cccc(Cl)c2)cc1)C(O)=O
Show InChI InChI=1S/C24H28ClNO4/c1-2-29-23(24(27)28)16-18-6-8-22(9-7-18)30-15-14-26-12-10-19(11-13-26)20-4-3-5-21(25)17-20/h3-10,17,23H,2,11-16H2,1H3,(H,27,28)
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n/an/an/an/a 3.24E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263703
PNG
(3-(4-(2-(4-(2-chlorophenyl)-5,6-dihydropyridin-1(2...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccccc2Cl)cc1)C(O)=O
Show InChI InChI=1S/C24H28ClNO4/c1-2-29-23(24(27)28)17-18-7-9-20(10-8-18)30-16-15-26-13-11-19(12-14-26)21-5-3-4-6-22(21)25/h3-11,23H,2,12-17H2,1H3,(H,27,28)
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n/an/an/an/a 7.72E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263704
PNG
(2-ethoxy-3-(4-(2-(4-(4-(trifluoromethyl)phenyl)-5,...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccc(cc2)C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C25H28F3NO4/c1-2-32-23(24(30)31)17-18-3-9-22(10-4-18)33-16-15-29-13-11-20(12-14-29)19-5-7-21(8-6-19)25(26,27)28/h3-11,23H,2,12-17H2,1H3,(H,30,31)
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n/an/an/an/a 3.40E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263705
PNG
(2-ethoxy-3-(4-(2-(4-(3-(trifluoromethyl)phenyl)-5,...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2cccc(c2)C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C25H28F3NO4/c1-2-32-23(24(30)31)16-18-6-8-22(9-7-18)33-15-14-29-12-10-19(11-13-29)20-4-3-5-21(17-20)25(26,27)28/h3-10,17,23H,2,11-16H2,1H3,(H,30,31)
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n/an/an/an/a 3.12E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263706
PNG
(2-ethoxy-3-(4-(2-(4-(2-(trifluoromethyl)phenyl)-5,...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccccc2C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C25H28F3NO4/c1-2-32-23(24(30)31)17-18-7-9-20(10-8-18)33-16-15-29-13-11-19(12-14-29)21-5-3-4-6-22(21)25(26,27)28/h3-11,23H,2,12-17H2,1H3,(H,30,31)
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n/an/an/an/a 542n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263747
PNG
(2-ethoxy-3-(4-(2-(4-(4-fluorophenyl)-5,6-dihydropy...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccc(F)cc2)cc1)C(O)=O
Show InChI InChI=1S/C24H28FNO4/c1-2-29-23(24(27)28)17-18-3-9-22(10-4-18)30-16-15-26-13-11-20(12-14-26)19-5-7-21(25)8-6-19/h3-11,23H,2,12-17H2,1H3,(H,27,28)
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n/an/an/an/a 2.23E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263748
PNG
(2-ethoxy-3-(4-(2-(4-(4-methoxyphenyl)-5,6-dihydrop...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccc(OC)cc2)cc1)C(O)=O
Show InChI InChI=1S/C25H31NO5/c1-3-30-24(25(27)28)18-19-4-8-23(9-5-19)31-17-16-26-14-12-21(13-15-26)20-6-10-22(29-2)11-7-20/h4-12,24H,3,13-18H2,1-2H3,(H,27,28)
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n/an/an/an/a 1.13E+4n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263749
PNG
(2-ethoxy-3-(4-(2-(4-(3-methoxyphenyl)-5,6-dihydrop...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2cccc(OC)c2)cc1)C(O)=O
Show InChI InChI=1S/C25H31NO5/c1-3-30-24(25(27)28)17-19-7-9-22(10-8-19)31-16-15-26-13-11-20(12-14-26)21-5-4-6-23(18-21)29-2/h4-11,18,24H,3,12-17H2,1-2H3,(H,27,28)
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n/an/an/an/a 1.73E+4n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263750
PNG
(2-ethoxy-3-(4-(2-(4-(2-methoxyphenyl)-5,6-dihydrop...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccccc2OC)cc1)C(O)=O
Show InChI InChI=1S/C25H31NO5/c1-3-30-24(25(27)28)18-19-8-10-21(11-9-19)31-17-16-26-14-12-20(13-15-26)22-6-4-5-7-23(22)29-2/h4-12,24H,3,13-18H2,1-2H3,(H,27,28)
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n/an/an/an/a 1.81E+4n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263796
PNG
(2-ethoxy-3-(4-(2-(4-(4-ethylphenyl)-5,6-dihydropyr...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccc(CC)cc2)cc1)C(O)=O
Show InChI InChI=1S/C26H33NO4/c1-3-20-5-9-22(10-6-20)23-13-15-27(16-14-23)17-18-31-24-11-7-21(8-12-24)19-25(26(28)29)30-4-2/h5-13,25H,3-4,14-19H2,1-2H3,(H,28,29)
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n/an/an/an/a 7.58E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263797
PNG
(2-ethoxy-3-(4-(2-(4-(4-propylphenyl)-5,6-dihydropy...)
Show SMILES CCCc1ccc(cc1)C1=CCN(CCOc2ccc(CC(OCC)C(O)=O)cc2)CC1
Show InChI InChI=1S/C27H35NO4/c1-3-5-21-6-10-23(11-7-21)24-14-16-28(17-15-24)18-19-32-25-12-8-22(9-13-25)20-26(27(29)30)31-4-2/h6-14,26H,3-5,15-20H2,1-2H3,(H,29,30)
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n/an/an/an/a 2.08E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263798
PNG
(3-(4-(2-(4-(2,3-dichlorophenyl)-5,6-dihydropyridin...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2cccc(Cl)c2Cl)cc1)C(O)=O
Show InChI InChI=1S/C24H27Cl2NO4/c1-2-30-22(24(28)29)16-17-6-8-19(9-7-17)31-15-14-27-12-10-18(11-13-27)20-4-3-5-21(25)23(20)26/h3-10,22H,2,11-16H2,1H3,(H,28,29)
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n/an/an/an/a 64n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263799
PNG
(3-(4-(2-(4-(2,4-dichlorophenyl)-5,6-dihydropyridin...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccc(Cl)cc2Cl)cc1)C(O)=O
Show InChI InChI=1S/C24H27Cl2NO4/c1-2-30-23(24(28)29)15-17-3-6-20(7-4-17)31-14-13-27-11-9-18(10-12-27)21-8-5-19(25)16-22(21)26/h3-9,16,23H,2,10-15H2,1H3,(H,28,29)
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n/an/an/an/a 1.12E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263847
PNG
(3-(4-(2-(4-(2,5-dichlorophenyl)-5,6-dihydropyridin...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2cc(Cl)ccc2Cl)cc1)C(O)=O
Show InChI InChI=1S/C24H27Cl2NO4/c1-2-30-23(24(28)29)15-17-3-6-20(7-4-17)31-14-13-27-11-9-18(10-12-27)21-16-19(25)5-8-22(21)26/h3-9,16,23H,2,10-15H2,1H3,(H,28,29)
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n/an/an/an/a 1.12E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263848
PNG
(3-(4-(2-(4-(3,4-dichlorophenyl)-5,6-dihydropyridin...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccc(Cl)c(Cl)c2)cc1)C(O)=O
Show InChI InChI=1S/C24H27Cl2NO4/c1-2-30-23(24(28)29)15-17-3-6-20(7-4-17)31-14-13-27-11-9-18(10-12-27)19-5-8-21(25)22(26)16-19/h3-9,16,23H,2,10-15H2,1H3,(H,28,29)
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n/an/an/an/a 1.15E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263849
PNG
((S)-3-(4-(2-(4-(3,4-dichlorophenyl)-5,6-dihydropyr...)
Show SMILES CCO[C@@H](Cc1ccc(OCCN2CCC(=CC2)c2ccc(Cl)c(Cl)c2)cc1)C(O)=O
Show InChI InChI=1S/C24H27Cl2NO4/c1-2-30-23(24(28)29)15-17-3-6-20(7-4-17)31-14-13-27-11-9-18(10-12-27)19-5-8-21(25)22(26)16-19/h3-9,16,23H,2,10-15H2,1H3,(H,28,29)/t23-/m0/s1
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n/an/an/an/a 615n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263850
PNG
(3-(4-(2-(4-(3,5-dichlorophenyl)-5,6-dihydropyridin...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2cc(Cl)cc(Cl)c2)cc1)C(O)=O
Show InChI InChI=1S/C24H27Cl2NO4/c1-2-30-23(24(28)29)13-17-3-5-22(6-4-17)31-12-11-27-9-7-18(8-10-27)19-14-20(25)16-21(26)15-19/h3-7,14-16,23H,2,8-13H2,1H3,(H,28,29)
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n/an/an/an/a 2.99E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263901
PNG
(2-ethoxy-3-(4-(2-(4-(pyridin-2-yl)-5,6-dihydropyri...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ccccn2)cc1)C(O)=O
Show InChI InChI=1S/C23H28N2O4/c1-2-28-22(23(26)27)17-18-6-8-20(9-7-18)29-16-15-25-13-10-19(11-14-25)21-5-3-4-12-24-21/h3-10,12,22H,2,11,13-17H2,1H3,(H,26,27)
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n/an/an/an/a 1.02E+4n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263902
PNG
(2-ethoxy-3-(4-(2-(4-(thiophen-2-yl)-5,6-dihydropyr...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2cccs2)cc1)C(O)=O
Show InChI InChI=1S/C22H27NO4S/c1-2-26-20(22(24)25)16-17-5-7-19(8-6-17)27-14-13-23-11-9-18(10-12-23)21-4-3-15-28-21/h3-9,15,20H,2,10-14,16H2,1H3,(H,24,25)
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n/an/an/an/a 8.58E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263903
PNG
(2-ethoxy-3-(4-(2-(4-(pyrazin-2-yl)-5,6-dihydropyri...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2cnccn2)cc1)C(O)=O
Show InChI InChI=1S/C22H27N3O4/c1-2-28-21(22(26)27)15-17-3-5-19(6-4-17)29-14-13-25-11-7-18(8-12-25)20-16-23-9-10-24-20/h3-7,9-10,16,21H,2,8,11-15H2,1H3,(H,26,27)
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n/an/an/an/a 3.67E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263904
PNG
(2-ethoxy-3-(4-(2-(4-(pyrimidin-2-yl)-5,6-dihydropy...)
Show SMILES CCOC(Cc1ccc(OCCN2CCC(=CC2)c2ncccn2)cc1)C(O)=O
Show InChI InChI=1S/C22H27N3O4/c1-2-28-20(22(26)27)16-17-4-6-19(7-5-17)29-15-14-25-12-8-18(9-13-25)21-23-10-3-11-24-21/h3-8,10-11,20H,2,9,12-16H2,1H3,(H,26,27)
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n/an/an/an/a 7.67E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263905
PNG
(3-(4-(3-(4-(4-chlorophenyl)-5,6-dihydropyridin-1(2...)
Show SMILES CCOC(Cc1ccc(OCCCN2CCC(=CC2)c2ccc(Cl)cc2)cc1)C(O)=O
Show InChI InChI=1S/C25H30ClNO4/c1-2-30-24(25(28)29)18-19-4-10-23(11-5-19)31-17-3-14-27-15-12-21(13-16-27)20-6-8-22(26)9-7-20/h4-12,24H,2-3,13-18H2,1H3,(H,28,29)
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n/an/an/an/a 9.80E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263953
PNG
(2-ethoxy-3-(4-(3-(4-(4-(trifluoromethyl)phenyl)-5,...)
Show SMILES CCOC(Cc1ccc(OCCCN2CCC(=CC2)c2ccc(cc2)C(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C26H30F3NO4/c1-2-33-24(25(31)32)18-19-4-10-23(11-5-19)34-17-3-14-30-15-12-21(13-16-30)20-6-8-22(9-7-20)26(27,28)29/h4-12,24H,2-3,13-18H2,1H3,(H,31,32)
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n/an/an/an/a 9.79E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50263954
PNG
(3-(4-(3-(4-(3,4-dichlorophenyl)-5,6-dihydropyridin...)
Show SMILES CCOC(Cc1ccc(OCCCN2CCC(=CC2)c2ccc(Cl)c(Cl)c2)cc1)C(O)=O
Show InChI InChI=1S/C25H29Cl2NO4/c1-2-31-24(25(29)30)16-18-4-7-21(8-5-18)32-15-3-12-28-13-10-19(11-14-28)20-6-9-22(26)23(27)17-20/h4-10,17,24H,2-3,11-16H2,1H3,(H,29,30)
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n/an/an/an/a 1.70E+3n/an/an/an/a



Yuhan Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assay


Bioorg Med Chem Lett 18: 4993-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.020
BindingDB Entry DOI: 10.7270/Q25B029G
More data for this
Ligand-Target Pair
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