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Compile Data Set for Download or QSAR

Found 48 hits with Last Name = 'aiello' and Initial = 'd'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DnaC helicase


(Staphylococcus aureus)
BDBM50295892
PNG
((Z)-5-(4-hydroxy-3,5-dimethoxybenzylidene)-3-(4-ni...)
Show SMILES COc1cc(\C=C2/SC(=S)N(C2=O)c2ccc(cc2)[N+]([O-])=O)cc(OC)c1O
Show InChI InChI=1S/C18H14N2O6S2/c1-25-13-7-10(8-14(26-2)16(13)21)9-15-17(22)19(18(27)28-15)11-3-5-12(6-4-11)20(23)24/h3-9,21H,1-2H3/b15-9-
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n/an/a 700n/an/an/an/an/an/a



Microbiotix, Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay


Bioorg Med Chem 17: 4466-76 (2009)


Article DOI: 10.1016/j.bmc.2009.05.014
BindingDB Entry DOI: 10.7270/Q22F7NGH
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400427
PNG
(CHEMBL2178445)
Show SMILES Cc1c(OCc2ccc(cc2)-c2ccc(Cl)cc2)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C27H23ClO5/c1-16-22-11-13-24(17(2)26(22)33-27(31)23(16)12-14-25(29)30)32-15-18-3-5-19(6-4-18)20-7-9-21(28)10-8-20/h3-11,13H,12,14-15H2,1-2H3,(H,29,30)
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n/an/a 1.50E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400420
PNG
(CHEMBL2178452)
Show SMILES CN(C)CCNC(=O)CCc1c(C)c2ccc(OCc3ccc(cc3)-c3ccccc3)c(C)c2oc1=O
Show InChI InChI=1S/C31H34N2O4/c1-21-26-14-16-28(36-20-23-10-12-25(13-11-23)24-8-6-5-7-9-24)22(2)30(26)37-31(35)27(21)15-17-29(34)32-18-19-33(3)4/h5-14,16H,15,17-20H2,1-4H3,(H,32,34)
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n/an/a 1.80E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400416
PNG
(CHEMBL2178456)
Show SMILES CCc1c(OCc2ccc(cc2)-c2ccccc2)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C28H26O5/c1-3-22-25(32-17-19-9-11-21(12-10-19)20-7-5-4-6-8-20)15-13-23-18(2)24(14-16-26(29)30)28(31)33-27(22)23/h4-13,15H,3,14,16-17H2,1-2H3,(H,29,30)
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n/an/a 2.00E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400418
PNG
(CHEMBL2178454)
Show SMILES Cc1c(OCc2ccc(cc2)-c2ccccc2)ccc2c(C)c(CCCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C28H26O5/c1-18-23-15-16-25(19(2)27(23)33-28(31)24(18)9-6-10-26(29)30)32-17-20-11-13-22(14-12-20)21-7-4-3-5-8-21/h3-5,7-8,11-16H,6,9-10,17H2,1-2H3,(H,29,30)
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n/an/a 2.00E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
DnaC helicase


(Staphylococcus aureus)
BDBM50295893
PNG
((Z)-3-(4-chlorophenyl)-5-(4-hydroxy-3,5-dimethoxyb...)
Show SMILES COc1cc(\C=C2/SC(=S)N(C2=O)c2ccc(Cl)cc2)cc(OC)c1O
Show InChI InChI=1S/C18H14ClNO4S2/c1-23-13-7-10(8-14(24-2)16(13)21)9-15-17(22)20(18(25)26-15)12-5-3-11(19)4-6-12/h3-9,21H,1-2H3/b15-9-
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n/an/a 2.00E+3n/an/an/an/an/an/a



Microbiotix, Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay


Bioorg Med Chem 17: 4466-76 (2009)


Article DOI: 10.1016/j.bmc.2009.05.014
BindingDB Entry DOI: 10.7270/Q22F7NGH
More data for this
Ligand-Target Pair
DnaC helicase


(Staphylococcus aureus)
BDBM50295894
PNG
((Z)-3-(3-chlorophenyl)-5-(4-hydroxy-3,5-dimethoxyb...)
Show SMILES COc1cc(\C=C2/SC(=S)N(C2=O)c2cccc(Cl)c2)cc(OC)c1O
Show InChI InChI=1S/C18H14ClNO4S2/c1-23-13-6-10(7-14(24-2)16(13)21)8-15-17(22)20(18(25)26-15)12-5-3-4-11(19)9-12/h3-9,21H,1-2H3/b15-8-
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n/an/a 3.00E+3n/an/an/an/an/an/a



Microbiotix, Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay


Bioorg Med Chem 17: 4466-76 (2009)


Article DOI: 10.1016/j.bmc.2009.05.014
BindingDB Entry DOI: 10.7270/Q22F7NGH
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400424
PNG
(CHEMBL2178448)
Show SMILES Cc1c(OCc2ccc(cc2)-c2ccc(Cl)c(Cl)c2)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C27H22Cl2O5/c1-15-20-8-11-24(16(2)26(20)34-27(32)21(15)9-12-25(30)31)33-14-17-3-5-18(6-4-17)19-7-10-22(28)23(29)13-19/h3-8,10-11,13H,9,12,14H2,1-2H3,(H,30,31)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400429
PNG
(CHEMBL2178443)
Show SMILES Cc1c(OCc2ccc(cc2)-c2ccccc2)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C27H24O5/c1-17-22-12-14-24(18(2)26(22)32-27(30)23(17)13-15-25(28)29)31-16-19-8-10-21(11-9-19)20-6-4-3-5-7-20/h3-12,14H,13,15-16H2,1-2H3,(H,28,29)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400428
PNG
(CHEMBL2178444)
Show SMILES Cc1c(OCc2ccc(cc2)-c2ccccc2C#N)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C28H23NO5/c1-17-22-11-13-25(18(2)27(22)34-28(32)23(17)12-14-26(30)31)33-16-19-7-9-20(10-8-19)24-6-4-3-5-21(24)15-29/h3-11,13H,12,14,16H2,1-2H3,(H,30,31)
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n/an/a 3.80E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
DnaC helicase


(Staphylococcus aureus)
BDBM11985
PNG
(4-(2,5-dimethyl-1H-pyrrol-1-yl)-2-hydroxybenzoic a...)
Show SMILES Cc1ccc(C)n1-c1ccc(C(O)=O)c(O)c1
Show InChI InChI=1S/C13H13NO3/c1-8-3-4-9(2)14(8)10-5-6-11(13(16)17)12(15)7-10/h3-7,15H,1-2H3,(H,16,17)
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n/an/a 4.00E+3n/an/an/an/an/an/a



Microbiotix, Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay


Bioorg Med Chem 17: 4466-76 (2009)


Article DOI: 10.1016/j.bmc.2009.05.014
BindingDB Entry DOI: 10.7270/Q22F7NGH
More data for this
Ligand-Target Pair
DnaC helicase


(Staphylococcus aureus)
BDBM11994
PNG
(2-{[4-(2,5-dimethyl-1H-pyrrol-1-yl)phenyl]sulfanyl...)
Show SMILES Cc1ccc(C)n1-c1ccc(SCC(O)=O)cc1
Show InChI InChI=1S/C14H15NO2S/c1-10-3-4-11(2)15(10)12-5-7-13(8-6-12)18-9-14(16)17/h3-8H,9H2,1-2H3,(H,16,17)
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n/an/a 4.00E+3n/an/an/an/an/an/a



Microbiotix, Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay


Bioorg Med Chem 17: 4466-76 (2009)


Article DOI: 10.1016/j.bmc.2009.05.014
BindingDB Entry DOI: 10.7270/Q22F7NGH
More data for this
Ligand-Target Pair
DnaC helicase


(Staphylococcus aureus)
BDBM50295891
PNG
((Z)-5-(4-hydroxy-3,5-dimethoxybenzylidene)-2-thiox...)
Show SMILES COc1cc(\C=C2/SC(=S)N(C2=O)c2cccc(c2)C(F)(F)F)cc(OC)c1O
Show InChI InChI=1S/C19H14F3NO4S2/c1-26-13-6-10(7-14(27-2)16(13)24)8-15-17(25)23(18(28)29-15)12-5-3-4-11(9-12)19(20,21)22/h3-9,24H,1-2H3/b15-8-
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n/an/a 4.00E+3n/an/an/an/an/an/a



Microbiotix, Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay


Bioorg Med Chem 17: 4466-76 (2009)


Article DOI: 10.1016/j.bmc.2009.05.014
BindingDB Entry DOI: 10.7270/Q22F7NGH
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400415
PNG
(CHEMBL2178457)
Show SMILES CCc1c(OCc2ccc(cc2)-c2ccccc2)ccc2c(C)c(CCCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C29H28O5/c1-3-23-26(33-18-20-12-14-22(15-13-20)21-8-5-4-6-9-21)17-16-24-19(2)25(10-7-11-27(30)31)29(32)34-28(23)24/h4-6,8-9,12-17H,3,7,10-11,18H2,1-2H3,(H,30,31)
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n/an/a 5.00E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400426
PNG
(CHEMBL2178446)
Show SMILES Cc1c(OCc2ccc(cc2)-c2ccc(F)cc2)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C27H23FO5/c1-16-22-11-13-24(17(2)26(22)33-27(31)23(16)12-14-25(29)30)32-15-18-3-5-19(6-4-18)20-7-9-21(28)10-8-20/h3-11,13H,12,14-15H2,1-2H3,(H,29,30)
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n/an/a 5.10E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400425
PNG
(CHEMBL2178447)
Show SMILES Cc1c(OCc2ccc(cc2)-c2ccc(cc2)C(F)(F)F)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C28H23F3O5/c1-16-22-11-13-24(17(2)26(22)36-27(34)23(16)12-14-25(32)33)35-15-18-3-5-19(6-4-18)20-7-9-21(10-8-20)28(29,30)31/h3-11,13H,12,14-15H2,1-2H3,(H,32,33)
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n/an/a 6.10E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400435
PNG
(CHEMBL2177806)
Show SMILES Cc1c(OCc2c3ccccc3cc3ccccc23)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C29H24O5/c1-17-21-11-13-26(18(2)28(21)34-29(32)22(17)12-14-27(30)31)33-16-25-23-9-5-3-7-19(23)15-20-8-4-6-10-24(20)25/h3-11,13,15H,12,14,16H2,1-2H3,(H,30,31)
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n/an/a 7.20E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400431
PNG
(CHEMBL2177810)
Show SMILES Cc1c(OCc2cccc(c2)-c2ccccc2)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C27H24O5/c1-17-22-11-13-24(18(2)26(22)32-27(30)23(17)12-14-25(28)29)31-16-19-7-6-10-21(15-19)20-8-4-3-5-9-20/h3-11,13,15H,12,14,16H2,1-2H3,(H,28,29)
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n/an/a 7.50E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400440
PNG
(CHEMBL2177801)
Show SMILES Cc1c(OCc2ccc3ccccc3c2)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C25H22O5/c1-15-20-9-11-22(16(2)24(20)30-25(28)21(15)10-12-23(26)27)29-14-17-7-8-18-5-3-4-6-19(18)13-17/h3-9,11,13H,10,12,14H2,1-2H3,(H,26,27)
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n/an/a 9.00E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400423
PNG
(CHEMBL2178449)
Show SMILES Cc1c(OCc2ccc(cc2)-c2ccc(F)cc2F)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C27H22F2O5/c1-15-20-9-11-24(16(2)26(20)34-27(32)21(15)10-12-25(30)31)33-14-17-3-5-18(6-4-17)22-8-7-19(28)13-23(22)29/h3-9,11,13H,10,12,14H2,1-2H3,(H,30,31)
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Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400419
PNG
(CHEMBL2178453)
Show SMILES Cc1c(OCc2ccc(cc2)-c2ccccc2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C26H22O5/c1-16-21-12-13-23(17(2)25(21)31-26(29)22(16)14-24(27)28)30-15-18-8-10-20(11-9-18)19-6-4-3-5-7-19/h3-13H,14-15H2,1-2H3,(H,27,28)
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n/an/a 9.00E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400430
PNG
(CHEMBL2177811)
Show SMILES Cc1c(CCC(O)=O)c(=O)oc2cc(OCc3ccc(cc3)-c3ccccc3)ccc12
Show InChI InChI=1S/C26H22O5/c1-17-22-12-11-21(15-24(22)31-26(29)23(17)13-14-25(27)28)30-16-18-7-9-20(10-8-18)19-5-3-2-4-6-19/h2-12,15H,13-14,16H2,1H3,(H,27,28)
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n/an/a 9.70E+3n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400434
PNG
(CHEMBL2177807)
Show SMILES Cc1c(OCc2ccccc2-c2ccccc2)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C27H24O5/c1-17-21-12-14-24(18(2)26(21)32-27(30)22(17)13-15-25(28)29)31-16-20-10-6-7-11-23(20)19-8-4-3-5-9-19/h3-12,14H,13,15-16H2,1-2H3,(H,28,29)
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n/an/a 1.02E+4n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
DnaC helicase


(Staphylococcus aureus)
BDBM50295886
PNG
(4-(2-methylthiazol-4-yl)-1H-pyrrole-2-carboxylic a...)
Show SMILES Cc1nc(cs1)-c1c[nH]c(c1)C(O)=O
Show InChI InChI=1S/C9H8N2O2S/c1-5-11-8(4-14-5)6-2-7(9(12)13)10-3-6/h2-4,10H,1H3,(H,12,13)
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n/an/a 1.20E+4n/an/an/an/an/an/a



Microbiotix, Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay


Bioorg Med Chem 17: 4466-76 (2009)


Article DOI: 10.1016/j.bmc.2009.05.014
BindingDB Entry DOI: 10.7270/Q22F7NGH
More data for this
Ligand-Target Pair
DnaC helicase


(Staphylococcus aureus)
BDBM50295898
PNG
(4-((4-amino-5-(2-fluorobenzyl)-4H-1,2,4-triazol-3-...)
Show SMILES Nn1c(Cc2ccccc2F)nnc1SCc1cc(=O)oc2cc(O)c(O)cc12
Show InChI InChI=1S/C19H15FN4O4S/c20-13-4-2-1-3-10(13)5-17-22-23-19(24(17)21)29-9-11-6-18(27)28-16-8-15(26)14(25)7-12(11)16/h1-4,6-8,25-26H,5,9,21H2
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n/an/a 1.50E+4n/an/an/an/an/an/a



Microbiotix, Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay


Bioorg Med Chem 17: 4466-76 (2009)


Article DOI: 10.1016/j.bmc.2009.05.014
BindingDB Entry DOI: 10.7270/Q22F7NGH
More data for this
Ligand-Target Pair
DnaC helicase


(Staphylococcus aureus)
BDBM50295897
PNG
(6,7-dihydroxy-4-((1-methyl-1H-benzo[d]imidazol-2-y...)
Show SMILES Cn1c(SCc2cc(=O)oc3cc(O)c(O)cc23)nc2ccccc12
Show InChI InChI=1S/C18H14N2O4S/c1-20-13-5-3-2-4-12(13)19-18(20)25-9-10-6-17(23)24-16-8-15(22)14(21)7-11(10)16/h2-8,21-22H,9H2,1H3
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Microbiotix, Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay


Bioorg Med Chem 17: 4466-76 (2009)


Article DOI: 10.1016/j.bmc.2009.05.014
BindingDB Entry DOI: 10.7270/Q22F7NGH
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400432
PNG
(CHEMBL2177809)
Show SMILES Cc1c(CCC(O)=O)c(=O)oc2cc(OCc3cccc(c3)-c3ccccc3)ccc12
Show InChI InChI=1S/C26H22O5/c1-17-22-11-10-21(15-24(22)31-26(29)23(17)12-13-25(27)28)30-16-18-6-5-9-20(14-18)19-7-3-2-4-8-19/h2-11,14-15H,12-13,16H2,1H3,(H,27,28)
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n/an/a 1.50E+4n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
DnaC helicase


(Staphylococcus aureus)
BDBM50295895
PNG
(3,4,5-trimethoxy-N-(6-(morpholinosulfonyl)benzo[d]...)
Show SMILES COc1cc(cc(OC)c1OC)C(=O)Nc1nc2ccc(cc2s1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C21H23N3O7S2/c1-28-16-10-13(11-17(29-2)19(16)30-3)20(25)23-21-22-15-5-4-14(12-18(15)32-21)33(26,27)24-6-8-31-9-7-24/h4-5,10-12H,6-9H2,1-3H3,(H,22,23,25)
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Microbiotix, Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay


Bioorg Med Chem 17: 4466-76 (2009)


Article DOI: 10.1016/j.bmc.2009.05.014
BindingDB Entry DOI: 10.7270/Q22F7NGH
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400433
PNG
(CHEMBL2177808)
Show SMILES Cc1c(CCC(O)=O)c(=O)oc2cc(OCc3ccccc3-c3ccccc3)ccc12
Show InChI InChI=1S/C26H22O5/c1-17-21-12-11-20(15-24(21)31-26(29)22(17)13-14-25(27)28)30-16-19-9-5-6-10-23(19)18-7-3-2-4-8-18/h2-12,15H,13-14,16H2,1H3,(H,27,28)
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n/an/a 1.90E+4n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
DnaC helicase


(Staphylococcus aureus)
BDBM50295889
PNG
(6-(benzofuran-2-yl)-N2-(4-methoxyphenyl)-1,3,5-tri...)
Show SMILES COc1ccc(Nc2nc(N)nc(n2)-c2cc3ccccc3o2)cc1
Show InChI InChI=1S/C18H15N5O2/c1-24-13-8-6-12(7-9-13)20-18-22-16(21-17(19)23-18)15-10-11-4-2-3-5-14(11)25-15/h2-10H,1H3,(H3,19,20,21,22,23)
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Microbiotix, Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay


Bioorg Med Chem 17: 4466-76 (2009)


Article DOI: 10.1016/j.bmc.2009.05.014
BindingDB Entry DOI: 10.7270/Q22F7NGH
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400417
PNG
(CHEMBL2178455)
Show SMILES Cc1c(OCc2ccc(cc2)-c2ccccc2)ccc2cc(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C26H22O5/c1-17-23(13-11-21-15-22(12-14-24(27)28)26(29)31-25(17)21)30-16-18-7-9-20(10-8-18)19-5-3-2-4-6-19/h2-11,13,15H,12,14,16H2,1H3,(H,27,28)
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Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
DnaC helicase


(Staphylococcus aureus)
BDBM34851
PNG
(3-benzyl-7,8-dihydroxy-4-methyl-2H-chromen-2-one |...)
Show SMILES Cc1c(Cc2ccccc2)c(=O)oc2c(O)c(O)ccc12
Show InChI InChI=1S/C17H14O4/c1-10-12-7-8-14(18)15(19)16(12)21-17(20)13(10)9-11-5-3-2-4-6-11/h2-8,18-19H,9H2,1H3
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n/an/a 4.20E+4n/an/an/an/an/an/a



Microbiotix, Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay


Bioorg Med Chem 17: 4466-76 (2009)


Article DOI: 10.1016/j.bmc.2009.05.014
BindingDB Entry DOI: 10.7270/Q22F7NGH
More data for this
Ligand-Target Pair
DnaC helicase


(Staphylococcus aureus)
BDBM50295890
PNG
(CHEMBL558246 | N-(4-(N-(3,4-dimethylisoxazol-5-yl)...)
Show SMILES Cc1noc(NS(=O)(=O)c2ccc(NC(=O)CSc3nnc(-c4ccccc4)c(n3)-c3ccccc3)cc2)c1C
Show InChI InChI=1S/C28H24N6O4S2/c1-18-19(2)33-38-27(18)34-40(36,37)23-15-13-22(14-16-23)29-24(35)17-39-28-30-25(20-9-5-3-6-10-20)26(31-32-28)21-11-7-4-8-12-21/h3-16,34H,17H2,1-2H3,(H,29,35)
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n/an/a 4.70E+4n/an/an/an/an/an/a



Microbiotix, Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay


Bioorg Med Chem 17: 4466-76 (2009)


Article DOI: 10.1016/j.bmc.2009.05.014
BindingDB Entry DOI: 10.7270/Q22F7NGH
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400439
PNG
(CHEMBL2177802)
Show SMILES Cc1c(OCc2ccc3ccc(Cl)cc3n2)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C24H20ClNO5/c1-13-18-7-9-21(14(2)23(18)31-24(29)19(13)8-10-22(27)28)30-12-17-6-4-15-3-5-16(25)11-20(15)26-17/h3-7,9,11H,8,10,12H2,1-2H3,(H,27,28)
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n/an/a 5.60E+4n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
DnaC helicase


(Staphylococcus aureus)
BDBM50295896
PNG
(2-ethoxy-N-(6-sulfamoylbenzo[d]thiazol-2-yl)benzam...)
Show SMILES CCOc1ccccc1C(=O)Nc1nc2ccc(cc2s1)S(N)(=O)=O
Show InChI InChI=1S/C16H15N3O4S2/c1-2-23-13-6-4-3-5-11(13)15(20)19-16-18-12-8-7-10(25(17,21)22)9-14(12)24-16/h3-9H,2H2,1H3,(H2,17,21,22)(H,18,19,20)
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Microbiotix, Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay


Bioorg Med Chem 17: 4466-76 (2009)


Article DOI: 10.1016/j.bmc.2009.05.014
BindingDB Entry DOI: 10.7270/Q22F7NGH
More data for this
Ligand-Target Pair
DnaC helicase


(Staphylococcus aureus)
BDBM50295899
PNG
(3-(4,8-dimethyl-7-(naphthalen-1-ylmethoxy)-2-oxo-2...)
Show SMILES Cc1c(OCc2cccc3ccccc23)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C25H22O5/c1-15-19-10-12-22(16(2)24(19)30-25(28)20(15)11-13-23(26)27)29-14-18-8-5-7-17-6-3-4-9-21(17)18/h3-10,12H,11,13-14H2,1-2H3,(H,26,27)
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n/an/a 6.50E+4n/an/an/an/an/an/a



Microbiotix, Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay


Bioorg Med Chem 17: 4466-76 (2009)


Article DOI: 10.1016/j.bmc.2009.05.014
BindingDB Entry DOI: 10.7270/Q22F7NGH
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400442
PNG
(CHEMBL2178460)
Show SMILES Cc1c(OCc2ccccc2)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C21H20O5/c1-13-16-8-10-18(25-12-15-6-4-3-5-7-15)14(2)20(16)26-21(24)17(13)9-11-19(22)23/h3-8,10H,9,11-12H2,1-2H3,(H,22,23)
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n/an/a 8.50E+4n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400441
PNG
(CHEMBL2177800)
Show SMILES Cc1c(OCc2ccncc2)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C20H19NO5/c1-12-15-3-5-17(25-11-14-7-9-21-10-8-14)13(2)19(15)26-20(24)16(12)4-6-18(22)23/h3,5,7-10H,4,6,11H2,1-2H3,(H,22,23)
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Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400436
PNG
(CHEMBL2177805)
Show SMILES Cc1c(CCC(O)=O)c(=O)oc2cc(OCc3nccc4ccccc34)ccc12
Show InChI InChI=1S/C23H19NO5/c1-14-17-7-6-16(12-21(17)29-23(27)18(14)8-9-22(25)26)28-13-20-19-5-3-2-4-15(19)10-11-24-20/h2-7,10-12H,8-9,13H2,1H3,(H,25,26)
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Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400422
PNG
(CHEMBL2178450)
Show SMILES CNC(=O)CCc1c(C)c2ccc(OCc3ccc(cc3)-c3ccc(Cl)cc3)c(C)c2oc1=O
Show InChI InChI=1S/C28H26ClNO4/c1-17-23-12-14-25(18(2)27(23)34-28(32)24(17)13-15-26(31)30-3)33-16-19-4-6-20(7-5-19)21-8-10-22(29)11-9-21/h4-12,14H,13,15-16H2,1-3H3,(H,30,31)
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Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400421
PNG
(CHEMBL2178451)
Show SMILES CC(=O)NCCNC(=O)CCc1c(C)c2ccc(OCc3ccc(cc3)-c3ccccc3)c(C)c2oc1=O
Show InChI InChI=1S/C31H32N2O5/c1-20-26-13-15-28(37-19-23-9-11-25(12-10-23)24-7-5-4-6-8-24)21(2)30(26)38-31(36)27(20)14-16-29(35)33-18-17-32-22(3)34/h4-13,15H,14,16-19H2,1-3H3,(H,32,34)(H,33,35)
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Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
DnaC helicase


(Staphylococcus aureus)
BDBM50295888
PNG
(2-(5-(5-mercapto-1,3,4-oxadiazol-2-yl)furan-2-yl)b...)
Show SMILES Oc1ccc(O)c(c1)-c1ccc(o1)-c1nnc(S)o1
Show InChI InChI=1S/C12H8N2O4S/c15-6-1-2-8(16)7(5-6)9-3-4-10(17-9)11-13-14-12(19)18-11/h1-5,15-16H,(H,14,19)
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Microbiotix, Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay


Bioorg Med Chem 17: 4466-76 (2009)


Article DOI: 10.1016/j.bmc.2009.05.014
BindingDB Entry DOI: 10.7270/Q22F7NGH
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400438
PNG
(CHEMBL2177803)
Show SMILES Cc1c(CCC(O)=O)c(=O)oc2cc(OCc3ccc4ccc(Cl)cc4n3)ccc12
Show InChI InChI=1S/C23H18ClNO5/c1-13-18-7-6-17(11-21(18)30-23(28)19(13)8-9-22(26)27)29-12-16-5-3-14-2-4-15(24)10-20(14)25-16/h2-7,10-11H,8-9,12H2,1H3,(H,26,27)
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Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
DnaC helicase


(Staphylococcus aureus)
BDBM50295887
PNG
(6-ethyl-9-mercapto-6-methyl-5,6-dihydrobenzo[h][1,...)
Show SMILES CCC1(C)Cc2ccccc2-c2nc3[nH][nH]c(=S)n3c(=O)c12
Show InChI InChI=1S/C16H16N4OS/c1-3-16(2)8-9-6-4-5-7-10(9)12-11(16)13(21)20-14(17-12)18-19-15(20)22/h4-7H,3,8H2,1-2H3,(H,17,18)(H,19,22)
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Microbiotix, Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay


Bioorg Med Chem 17: 4466-76 (2009)


Article DOI: 10.1016/j.bmc.2009.05.014
BindingDB Entry DOI: 10.7270/Q22F7NGH
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400443
PNG
(CHEMBL2178459)
Show SMILES Cc1c(OCC#C)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C17H16O5/c1-4-9-21-14-7-5-12-10(2)13(6-8-15(18)19)17(20)22-16(12)11(14)3/h1,5,7H,6,8-9H2,2-3H3,(H,18,19)
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Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400444
PNG
(CHEMBL2178458)
Show SMILES Cc1c(OCC=C)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C17H18O5/c1-4-9-21-14-7-5-12-10(2)13(6-8-15(18)19)17(20)22-16(12)11(14)3/h4-5,7H,1,6,8-9H2,2-3H3,(H,18,19)
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Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
Replicative DNA helicase


(Bacillus anthracis)
BDBM50400437
PNG
(CHEMBL2177804)
Show SMILES Cc1c(OCc2nccc3ccccc23)ccc2c(C)c(CCC(O)=O)c(=O)oc12
Show InChI InChI=1S/C24H21NO5/c1-14-17-7-9-21(15(2)23(17)30-24(28)18(14)8-10-22(26)27)29-13-20-19-6-4-3-5-16(19)11-12-25-20/h3-7,9,11-12H,8,10,13H2,1-2H3,(H,26,27)
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Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay


J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair
DnaC helicase


(Staphylococcus aureus)
BDBM50295900
PNG
(3-(7-(4-bromo-2-fluorobenzyloxy)-4,8-dimethyl-2-ox...)
Show SMILES Cc1c(CCC(O)=O)c(=O)oc2c(C)c(OCc3ccc(Br)cc3F)ccc12
Show InChI InChI=1S/C21H18BrFO5/c1-11-15-5-7-18(27-10-13-3-4-14(22)9-17(13)23)12(2)20(15)28-21(26)16(11)6-8-19(24)25/h3-5,7,9H,6,8,10H2,1-2H3,(H,24,25)
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n/an/a 1.80E+5n/an/an/an/an/an/a



Microbiotix, Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay


Bioorg Med Chem 17: 4466-76 (2009)


Article DOI: 10.1016/j.bmc.2009.05.014
BindingDB Entry DOI: 10.7270/Q22F7NGH
More data for this
Ligand-Target Pair