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Compile Data Set for Download or QSAR

Found 66 hits with Last Name = 'akira' and Initial = 't'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50201292
PNG
(7,8-dichloro-N,N-dimethyl-3-((2-(tetrahydro-2H-pyr...)
Show SMILES CN(C)C1(CNCCC2CCOCC2)COc2cc(Cl)c(Cl)cc2OC1
Show InChI InChI=1S/C19H28Cl2N2O3/c1-23(2)19(11-22-6-3-14-4-7-24-8-5-14)12-25-17-9-15(20)16(21)10-18(17)26-13-19/h9-10,14,22H,3-8,11-13H2,1-2H3
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0.120n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201292
PNG
(7,8-dichloro-N,N-dimethyl-3-((2-(tetrahydro-2H-pyr...)
Show SMILES CN(C)C1(CNCCC2CCOCC2)COc2cc(Cl)c(Cl)cc2OC1
Show InChI InChI=1S/C19H28Cl2N2O3/c1-23(2)19(11-22-6-3-14-4-7-24-8-5-14)12-25-17-9-15(20)16(21)10-18(17)26-13-19/h9-10,14,22H,3-8,11-13H2,1-2H3
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0.220n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50201280
PNG
(CHEMBL394137 | {3-[(2-adamantan-1-yl-ethylamino)-m...)
Show SMILES CN(C)C1(CNCCC23CC4CC(CC(C4)C2)C3)COc2ccccc2OC1
Show InChI InChI=1S/C24H36N2O2/c1-26(2)24(16-27-21-5-3-4-6-22(21)28-17-24)15-25-8-7-23-12-18-9-19(13-23)11-20(10-18)14-23/h3-6,18-20,25H,7-17H2,1-2H3
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0.660n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50165019
PNG
(4-(Diethylamino)-2-butynyl alpha-phenylcyclohexane...)
Show SMILES CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)c1ccccc1
Show InChI InChI=1S/C22H31NO3/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3
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0.780n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50165019
PNG
(4-(Diethylamino)-2-butynyl alpha-phenylcyclohexane...)
Show SMILES CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)c1ccccc1
Show InChI InChI=1S/C22H31NO3/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3
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1n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201280
PNG
(CHEMBL394137 | {3-[(2-adamantan-1-yl-ethylamino)-m...)
Show SMILES CN(C)C1(CNCCC23CC4CC(CC(C4)C2)C3)COc2ccccc2OC1
Show InChI InChI=1S/C24H36N2O2/c1-26(2)24(16-27-21-5-3-4-6-22(21)28-17-24)15-25-8-7-23-12-18-9-19(13-23)11-20(10-18)14-23/h3-6,18-20,25H,7-17H2,1-2H3
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1.5n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50201292
PNG
(7,8-dichloro-N,N-dimethyl-3-((2-(tetrahydro-2H-pyr...)
Show SMILES CN(C)C1(CNCCC2CCOCC2)COc2cc(Cl)c(Cl)cc2OC1
Show InChI InChI=1S/C19H28Cl2N2O3/c1-23(2)19(11-22-6-3-14-4-7-24-8-5-14)12-25-17-9-15(20)16(21)10-18(17)26-13-19/h9-10,14,22H,3-8,11-13H2,1-2H3
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1.80n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50201277
PNG
((4-(2-((3-(dimethylamino)-3,4-dihydro-2H-benzo[b][...)
Show SMILES CN(C)C1(CNCCC2CCC(CO)CC2)COc2ccccc2OC1
Show InChI InChI=1S/C21H34N2O3/c1-23(2)21(15-25-19-5-3-4-6-20(19)26-16-21)14-22-12-11-17-7-9-18(13-24)10-8-17/h3-6,17-18,22,24H,7-16H2,1-2H3
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1.80n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50201296
PNG
(4-(2-((3-(dimethylamino)-3,4-dihydro-2H-benzo[b][1...)
Show SMILES CN(C)C1(CNCCC2CCC(O)CC2)COc2ccccc2OC1
Show InChI InChI=1S/C20H32N2O3/c1-22(2)20(13-21-12-11-16-7-9-17(23)10-8-16)14-24-18-5-3-4-6-19(18)25-15-20/h3-6,16-17,21,23H,7-15H2,1-2H3
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1.90n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50201285
PNG
(3-((2-cycloheptylethylamino)methyl)-N,N-dimethyl-3...)
Show SMILES CN(C)C1(CNCCC2CCCCCC2)COc2ccccc2OC1
Show InChI InChI=1S/C21H34N2O2/c1-23(2)21(15-22-14-13-18-9-5-3-4-6-10-18)16-24-19-11-7-8-12-20(19)25-17-21/h7-8,11-12,18,22H,3-6,9-10,13-17H2,1-2H3
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2n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201277
PNG
((4-(2-((3-(dimethylamino)-3,4-dihydro-2H-benzo[b][...)
Show SMILES CN(C)C1(CNCCC2CCC(CO)CC2)COc2ccccc2OC1
Show InChI InChI=1S/C21H34N2O3/c1-23(2)21(15-25-19-5-3-4-6-20(19)26-16-21)14-22-12-11-17-7-9-18(13-24)10-8-17/h3-6,17-18,22,24H,7-16H2,1-2H3
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2.10n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50201294
PNG
(3-((2-cyclopentylethylamino)methyl)-N,N-dimethyl-3...)
Show SMILES CN(C)C1(CNCCC2CCCC2)COc2ccccc2OC1
Show InChI InChI=1S/C19H30N2O2/c1-21(2)19(13-20-12-11-16-7-3-4-8-16)14-22-17-9-5-6-10-18(17)23-15-19/h5-6,9-10,16,20H,3-4,7-8,11-15H2,1-2H3
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2.40n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201283
PNG
(3-((2-cyclohexylethylamino)methyl)-N,N-dimethyl-3,...)
Show SMILES CN(C)C1(CNCCC2CCCCC2)COc2ccccc2OC1
Show InChI InChI=1S/C20H32N2O2/c1-22(2)20(14-21-13-12-17-8-4-3-5-9-17)15-23-18-10-6-7-11-19(18)24-16-20/h6-7,10-11,17,21H,3-5,8-9,12-16H2,1-2H3
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2.5n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201285
PNG
(3-((2-cycloheptylethylamino)methyl)-N,N-dimethyl-3...)
Show SMILES CN(C)C1(CNCCC2CCCCCC2)COc2ccccc2OC1
Show InChI InChI=1S/C21H34N2O2/c1-23(2)21(15-22-14-13-18-9-5-3-4-6-10-18)16-24-19-11-7-8-12-20(19)25-17-21/h7-8,11-12,18,22H,3-6,9-10,13-17H2,1-2H3
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2.70n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201296
PNG
(4-(2-((3-(dimethylamino)-3,4-dihydro-2H-benzo[b][1...)
Show SMILES CN(C)C1(CNCCC2CCC(O)CC2)COc2ccccc2OC1
Show InChI InChI=1S/C20H32N2O3/c1-22(2)20(13-21-12-11-16-7-9-17(23)10-8-16)14-24-18-5-3-4-6-19(18)25-15-20/h3-6,16-17,21,23H,7-15H2,1-2H3
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2.90n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201294
PNG
(3-((2-cyclopentylethylamino)methyl)-N,N-dimethyl-3...)
Show SMILES CN(C)C1(CNCCC2CCCC2)COc2ccccc2OC1
Show InChI InChI=1S/C19H30N2O2/c1-21(2)19(13-20-12-11-16-7-3-4-8-16)14-22-17-9-5-6-10-18(17)23-15-19/h5-6,9-10,16,20H,3-4,7-8,11-15H2,1-2H3
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3.30n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201299
PNG
(7-fluoro-N,N-dimethyl-3-((2-(tetrahydro-2H-pyran-4...)
Show SMILES CN(C)C1(CNCCC2CCOCC2)COc2ccc(F)cc2OC1
Show InChI InChI=1S/C19H29FN2O3/c1-22(2)19(12-21-8-5-15-6-9-23-10-7-15)13-24-17-4-3-16(20)11-18(17)25-14-19/h3-4,11,15,21H,5-10,12-14H2,1-2H3
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4.20n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201284
PNG
(3-((cyclohexylmethylamino)methyl)-N,N-dimethyl-3,4...)
Show SMILES CN(C)C1(CNCC2CCCCC2)COc2ccccc2OC1
Show InChI InChI=1S/C19H30N2O2/c1-21(2)19(13-20-12-16-8-4-3-5-9-16)14-22-17-10-6-7-11-18(17)23-15-19/h6-7,10-11,16,20H,3-5,8-9,12-15H2,1-2H3
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4.90n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50201299
PNG
(7-fluoro-N,N-dimethyl-3-((2-(tetrahydro-2H-pyran-4...)
Show SMILES CN(C)C1(CNCCC2CCOCC2)COc2ccc(F)cc2OC1
Show InChI InChI=1S/C19H29FN2O3/c1-22(2)19(12-21-8-5-15-6-9-23-10-7-15)13-24-17-4-3-16(20)11-18(17)25-14-19/h3-4,11,15,21H,5-10,12-14H2,1-2H3
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5.10n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201276
PNG
(3-((2-(3,6-dihydro-2H-thiopyran-4-yl)ethylamino)me...)
Show SMILES CN(C)C1(CNCCC2=CCSCC2)COc2ccccc2OC1
Show InChI InChI=1S/C19H28N2O2S/c1-21(2)19(13-20-10-7-16-8-11-24-12-9-16)14-22-17-5-3-4-6-18(17)23-15-19/h3-6,8,20H,7,9-15H2,1-2H3
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5.80n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50201280
PNG
(CHEMBL394137 | {3-[(2-adamantan-1-yl-ethylamino)-m...)
Show SMILES CN(C)C1(CNCCC23CC4CC(CC(C4)C2)C3)COc2ccccc2OC1
Show InChI InChI=1S/C24H36N2O2/c1-26(2)24(16-27-21-5-3-4-6-22(21)28-17-24)15-25-8-7-23-12-18-9-19(13-23)11-20(10-18)14-23/h3-6,18-20,25H,7-17H2,1-2H3
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5.90n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50201287
PNG
(CHEMBL435353 | N,N-dimethyl-3-((2-(tetrahydro-2H-p...)
Show SMILES CN(C)C1(CNCCC2CCOCC2)COc2ccccc2OC1
Show InChI InChI=1S/C19H30N2O3/c1-21(2)19(13-20-10-7-16-8-11-22-12-9-16)14-23-17-5-3-4-6-18(17)24-15-19/h3-6,16,20H,7-15H2,1-2H3
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6n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50201283
PNG
(3-((2-cyclohexylethylamino)methyl)-N,N-dimethyl-3,...)
Show SMILES CN(C)C1(CNCCC2CCCCC2)COc2ccccc2OC1
Show InChI InChI=1S/C20H32N2O2/c1-22(2)20(14-21-13-12-17-8-4-3-5-9-17)15-23-18-10-6-7-11-19(18)24-16-20/h6-7,10-11,17,21H,3-5,8-9,12-16H2,1-2H3
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6.20n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201286
PNG
(CHEMBL233201 | N,N-dimethyl-3-((2-(tetrahydro-2H-t...)
Show SMILES CN(C)C1(CNCCC2CCSCC2)COc2ccccc2OC1
Show InChI InChI=1S/C19H30N2O2S/c1-21(2)19(13-20-10-7-16-8-11-24-12-9-16)14-22-17-5-3-4-6-18(17)23-15-19/h3-6,16,20H,7-15H2,1-2H3
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6.80n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50201286
PNG
(CHEMBL233201 | N,N-dimethyl-3-((2-(tetrahydro-2H-t...)
Show SMILES CN(C)C1(CNCCC2CCSCC2)COc2ccccc2OC1
Show InChI InChI=1S/C19H30N2O2S/c1-21(2)19(13-20-10-7-16-8-11-24-12-9-16)14-22-17-5-3-4-6-18(17)23-15-19/h3-6,16,20H,7-15H2,1-2H3
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7.20n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50165019
PNG
(4-(Diethylamino)-2-butynyl alpha-phenylcyclohexane...)
Show SMILES CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)c1ccccc1
Show InChI InChI=1S/C22H31NO3/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3
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8.10n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50201291
PNG
(CHEMBL394255 | N,N-dimethyl-3-((2-(tetrahydropyran...)
Show SMILES CN(C)C1(CNCC=C2CCOCC2)COc2ccccc2OC1
Show InChI InChI=1S/C19H28N2O3/c1-21(2)19(13-20-10-7-16-8-11-22-12-9-16)14-23-17-5-3-4-6-18(17)24-15-19/h3-7,20H,8-15H2,1-2H3
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8.80n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201287
PNG
(CHEMBL435353 | N,N-dimethyl-3-((2-(tetrahydro-2H-p...)
Show SMILES CN(C)C1(CNCCC2CCOCC2)COc2ccccc2OC1
Show InChI InChI=1S/C19H30N2O3/c1-21(2)19(13-20-10-7-16-8-11-22-12-9-16)14-23-17-5-3-4-6-18(17)24-15-19/h3-6,16,20H,7-15H2,1-2H3
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11n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50201285
PNG
(3-((2-cycloheptylethylamino)methyl)-N,N-dimethyl-3...)
Show SMILES CN(C)C1(CNCCC2CCCCCC2)COc2ccccc2OC1
Show InChI InChI=1S/C21H34N2O2/c1-23(2)21(15-22-14-13-18-9-5-3-4-6-10-18)16-24-19-11-7-8-12-20(19)25-17-21/h7-8,11-12,18,22H,3-6,9-10,13-17H2,1-2H3
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12n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50201276
PNG
(3-((2-(3,6-dihydro-2H-thiopyran-4-yl)ethylamino)me...)
Show SMILES CN(C)C1(CNCCC2=CCSCC2)COc2ccccc2OC1
Show InChI InChI=1S/C19H28N2O2S/c1-21(2)19(13-20-10-7-16-8-11-24-12-9-16)14-22-17-5-3-4-6-18(17)23-15-19/h3-6,8,20H,7,9-15H2,1-2H3
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12n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50201284
PNG
(3-((cyclohexylmethylamino)methyl)-N,N-dimethyl-3,4...)
Show SMILES CN(C)C1(CNCC2CCCCC2)COc2ccccc2OC1
Show InChI InChI=1S/C19H30N2O2/c1-21(2)19(13-20-12-16-8-4-3-5-9-16)14-22-17-10-6-7-11-18(17)23-15-19/h6-7,10-11,16,20H,3-5,8-9,12-15H2,1-2H3
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12n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201291
PNG
(CHEMBL394255 | N,N-dimethyl-3-((2-(tetrahydropyran...)
Show SMILES CN(C)C1(CNCC=C2CCOCC2)COc2ccccc2OC1
Show InChI InChI=1S/C19H28N2O3/c1-21(2)19(13-20-10-7-16-8-11-22-12-9-16)14-23-17-5-3-4-6-18(17)24-15-19/h3-7,20H,8-15H2,1-2H3
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14n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50201283
PNG
(3-((2-cyclohexylethylamino)methyl)-N,N-dimethyl-3,...)
Show SMILES CN(C)C1(CNCCC2CCCCC2)COc2ccccc2OC1
Show InChI InChI=1S/C20H32N2O2/c1-22(2)20(14-21-13-12-17-8-4-3-5-9-17)15-23-18-10-6-7-11-19(18)24-16-20/h6-7,10-11,17,21H,3-5,8-9,12-16H2,1-2H3
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18n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201281
PNG
(CHEMBL234253 | dimethyl-{3-[(2-p-tolyl-ethylamino)...)
Show SMILES CN(C)C1(CNCCc2ccc(C)cc2)COc2ccccc2OC1
Show InChI InChI=1S/C21H28N2O2/c1-17-8-10-18(11-9-17)12-13-22-14-21(23(2)3)15-24-19-6-4-5-7-20(19)25-16-21/h4-11,22H,12-16H2,1-3H3
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18n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50201277
PNG
((4-(2-((3-(dimethylamino)-3,4-dihydro-2H-benzo[b][...)
Show SMILES CN(C)C1(CNCCC2CCC(CO)CC2)COc2ccccc2OC1
Show InChI InChI=1S/C21H34N2O3/c1-23(2)21(15-25-19-5-3-4-6-20(19)26-16-21)14-22-12-11-17-7-9-18(13-24)10-8-17/h3-6,17-18,22,24H,7-16H2,1-2H3
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18n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201278
PNG
(3-((2-fluorophenethylamino)methyl)-N,N-dimethyl-3,...)
Show SMILES CN(C)C1(CNCCc2ccccc2F)COc2ccccc2OC1
Show InChI InChI=1S/C20H25FN2O2/c1-23(2)20(13-22-12-11-16-7-3-4-8-17(16)21)14-24-18-9-5-6-10-19(18)25-15-20/h3-10,22H,11-15H2,1-2H3
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19n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50201296
PNG
(4-(2-((3-(dimethylamino)-3,4-dihydro-2H-benzo[b][1...)
Show SMILES CN(C)C1(CNCCC2CCC(O)CC2)COc2ccccc2OC1
Show InChI InChI=1S/C20H32N2O3/c1-22(2)20(13-21-12-11-16-7-9-17(23)10-8-16)14-24-18-5-3-4-6-19(18)25-15-20/h3-6,16-17,21,23H,7-15H2,1-2H3
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19n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201289
PNG
(CHEMBL234252 | N,N-dimethyl-3-((phenethylamino)met...)
Show SMILES CN(C)C1(CNCCc2ccccc2)COc2ccccc2OC1
Show InChI InChI=1S/C20H26N2O2/c1-22(2)20(14-21-13-12-17-8-4-3-5-9-17)15-23-18-10-6-7-11-19(18)24-16-20/h3-11,21H,12-16H2,1-2H3
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20n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201279
PNG
(3-((4-chlorophenethylamino)methyl)-N,N-dimethyl-3,...)
Show SMILES CN(C)C1(CNCCc2ccc(Cl)cc2)COc2ccccc2OC1
Show InChI InChI=1S/C20H25ClN2O2/c1-23(2)20(13-22-12-11-16-7-9-17(21)10-8-16)14-24-18-5-3-4-6-19(18)25-15-20/h3-10,22H,11-15H2,1-2H3
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20n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50201294
PNG
(3-((2-cyclopentylethylamino)methyl)-N,N-dimethyl-3...)
Show SMILES CN(C)C1(CNCCC2CCCC2)COc2ccccc2OC1
Show InChI InChI=1S/C19H30N2O2/c1-21(2)19(13-20-12-11-16-7-3-4-8-16)14-22-17-9-5-6-10-18(17)23-15-19/h5-6,9-10,16,20H,3-4,7-8,11-15H2,1-2H3
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21n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201295
PNG
(3-((2,6-dichlorophenethylamino)methyl)-N,N-dimethy...)
Show SMILES CN(C)C1(CNCCc2c(Cl)cccc2Cl)COc2ccccc2OC1
Show InChI InChI=1S/C20H24Cl2N2O2/c1-24(2)20(13-25-18-8-3-4-9-19(18)26-14-20)12-23-11-10-15-16(21)6-5-7-17(15)22/h3-9,23H,10-14H2,1-2H3
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23n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50201284
PNG
(3-((cyclohexylmethylamino)methyl)-N,N-dimethyl-3,4...)
Show SMILES CN(C)C1(CNCC2CCCCC2)COc2ccccc2OC1
Show InChI InChI=1S/C19H30N2O2/c1-21(2)19(13-20-12-16-8-4-3-5-9-16)14-22-17-10-6-7-11-18(17)23-15-19/h6-7,10-11,16,20H,3-5,8-9,12-15H2,1-2H3
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31n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50201299
PNG
(7-fluoro-N,N-dimethyl-3-((2-(tetrahydro-2H-pyran-4...)
Show SMILES CN(C)C1(CNCCC2CCOCC2)COc2ccc(F)cc2OC1
Show InChI InChI=1S/C19H29FN2O3/c1-22(2)19(12-21-8-5-15-6-9-23-10-7-15)13-24-17-4-3-16(20)11-18(17)25-14-19/h3-4,11,15,21H,5-10,12-14H2,1-2H3
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36n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50201278
PNG
(3-((2-fluorophenethylamino)methyl)-N,N-dimethyl-3,...)
Show SMILES CN(C)C1(CNCCc2ccccc2F)COc2ccccc2OC1
Show InChI InChI=1S/C20H25FN2O2/c1-23(2)20(13-22-12-11-16-7-3-4-8-17(16)21)14-24-18-9-5-6-10-19(18)25-15-20/h3-10,22H,11-15H2,1-2H3
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41n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50201293
PNG
(3-((4-isopropylphenethylamino)methyl)-N,N-dimethyl...)
Show SMILES CC(C)c1ccc(CCNCC2(COc3ccccc3OC2)N(C)C)cc1
Show InChI InChI=1S/C23H32N2O2/c1-18(2)20-11-9-19(10-12-20)13-14-24-15-23(25(3)4)16-26-21-7-5-6-8-22(21)27-17-23/h5-12,18,24H,13-17H2,1-4H3
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44n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50201281
PNG
(CHEMBL234253 | dimethyl-{3-[(2-p-tolyl-ethylamino)...)
Show SMILES CN(C)C1(CNCCc2ccc(C)cc2)COc2ccccc2OC1
Show InChI InChI=1S/C21H28N2O2/c1-17-8-10-18(11-9-17)12-13-22-14-21(23(2)3)15-24-19-6-4-5-7-20(19)25-16-21/h4-11,22H,12-16H2,1-3H3
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48n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50201295
PNG
(3-((2,6-dichlorophenethylamino)methyl)-N,N-dimethy...)
Show SMILES CN(C)C1(CNCCc2c(Cl)cccc2Cl)COc2ccccc2OC1
Show InChI InChI=1S/C20H24Cl2N2O2/c1-24(2)20(13-25-18-8-3-4-9-19(18)26-14-20)12-23-11-10-15-16(21)6-5-7-17(15)22/h3-9,23H,10-14H2,1-2H3
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49n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50201279
PNG
(3-((4-chlorophenethylamino)methyl)-N,N-dimethyl-3,...)
Show SMILES CN(C)C1(CNCCc2ccc(Cl)cc2)COc2ccccc2OC1
Show InChI InChI=1S/C20H25ClN2O2/c1-23(2)20(13-22-12-11-16-7-9-17(21)10-8-16)14-24-18-5-3-4-6-19(18)25-15-20/h3-10,22H,11-15H2,1-2H3
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49n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50201286
PNG
(CHEMBL233201 | N,N-dimethyl-3-((2-(tetrahydro-2H-t...)
Show SMILES CN(C)C1(CNCCC2CCSCC2)COc2ccccc2OC1
Show InChI InChI=1S/C19H30N2O2S/c1-21(2)19(13-20-10-7-16-8-11-24-12-9-16)14-22-17-5-3-4-6-18(17)23-15-19/h3-6,16,20H,7-15H2,1-2H3
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52n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(Homo sapiens (Human))
BDBM50201293
PNG
(3-((4-isopropylphenethylamino)methyl)-N,N-dimethyl...)
Show SMILES CC(C)c1ccc(CCNCC2(COc3ccccc3OC2)N(C)C)cc1
Show InChI InChI=1S/C23H32N2O2/c1-18(2)20-11-9-19(10-12-20)13-14-24-15-23(25(3)4)16-26-21-7-5-6-8-22(21)27-17-23/h5-12,18,24H,13-17H2,1-4H3
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56n/an/an/an/an/an/an/an/a



Mitsubishi Pharma Corporation

Curated by ChEMBL


Assay Description
Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells


Bioorg Med Chem Lett 17: 925-31 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.058
BindingDB Entry DOI: 10.7270/Q2DB81HZ
More data for this
Ligand-Target Pair
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