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Compile Data Set for Download or QSAR

Found 93 hits with Last Name = 'al-obaid' and Initial = 'am'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dihydrofolate reductase


(Homo sapiens (human))
BDBM18050
PNG
(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Show SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Show InChI InChI=1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1
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n/an/a 80n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM18050
PNG
(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Show SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Show InChI InChI=1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1
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n/an/a 80n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM11639
PNG
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
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n/an/a 300n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...


Eur J Med Chem 115: 121-31 (2016)


Article DOI: 10.1016/j.ejmech.2016.03.011
BindingDB Entry DOI: 10.7270/Q22N545K
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM50316117
PNG
(2-Allylthio-3-benzyl-6-diallylamino-quinazolin-4(3...)
Show SMILES C=CCSc1nc2ccc(cc2c(=O)n1Cc1ccccc1)N(CC=C)CC=C
Show InChI InChI=1S/C24H25N3OS/c1-4-14-26(15-5-2)20-12-13-22-21(17-20)23(28)27(24(25-22)29-16-6-3)18-19-10-8-7-9-11-19/h4-13,17H,1-3,14-16,18H2
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King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50161267
PNG
(CHEMBL3785126)
Show SMILES NS(=O)(=O)c1ccc(NC(=O)CCN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C24H22N4O5S/c25-34(32,33)20-13-11-19(12-14-20)26-21(29)15-16-28-22(30)24(27-23(28)31,17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-14H,15-16H2,(H,26,29)(H,27,31)(H2,25,32,33)
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King Saud University

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...


Eur J Med Chem 115: 121-31 (2016)


Article DOI: 10.1016/j.ejmech.2016.03.011
BindingDB Entry DOI: 10.7270/Q22N545K
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50161263
PNG
(CHEMBL3786373)
Show SMILES NS(=O)(=O)c1ccc(CNC(=O)CN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C24H22N4O5S/c25-34(32,33)20-13-11-17(12-14-20)15-26-21(29)16-28-22(30)24(27-23(28)31,18-7-3-1-4-8-18)19-9-5-2-6-10-19/h1-14H,15-16H2,(H,26,29)(H,27,31)(H2,25,32,33)
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King Saud University

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...


Eur J Med Chem 115: 121-31 (2016)


Article DOI: 10.1016/j.ejmech.2016.03.011
BindingDB Entry DOI: 10.7270/Q22N545K
More data for this
Ligand-Target Pair
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM50316112
PNG
(2-Allylthio-3-benzyl-6-dicinnamylamino-quinazolin-...)
Show SMILES C=CCSc1nc2ccc(cc2c(=O)n1Cc1ccccc1)N(C\C=C\c1ccccc1)C\C=C\c1ccccc1
Show InChI InChI=1S/C36H33N3OS/c1-2-26-41-36-37-34-23-22-32(27-33(34)35(40)39(36)28-31-18-10-5-11-19-31)38(24-12-20-29-14-6-3-7-15-29)25-13-21-30-16-8-4-9-17-30/h2-23,27H,1,24-26,28H2/b20-12+,21-13+
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King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316122
PNG
(CHEMBL1093519 | N-(2-Allylthio-3-benzyl-4-oxo-3,4-...)
Show SMILES C=CCSc1nc2ccc(NC(=O)\C=C\c3ccccc3)cc2c(=O)n1Cc1ccccc1
Show InChI InChI=1S/C27H23N3O2S/c1-2-17-33-27-29-24-15-14-22(28-25(31)16-13-20-9-5-3-6-10-20)18-23(24)26(32)30(27)19-21-11-7-4-8-12-21/h2-16,18H,1,17,19H2,(H,28,31)/b16-13+
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King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316121
PNG
(CHEMBL1089229 | N-(3-Benzyl-2-cinnamylthio-4-oxo-3...)
Show SMILES O=C(Nc1ccc2nc(SC\C=C\c3ccccc3)n(Cc3ccccc3)c(=O)c2c1)\C=C\c1ccccc1
Show InChI InChI=1S/C33H27N3O2S/c37-31(21-18-26-13-6-2-7-14-26)34-28-19-20-30-29(23-28)32(38)36(24-27-15-8-3-9-16-27)33(35-30)39-22-10-17-25-11-4-1-5-12-25/h1-21,23H,22,24H2,(H,34,37)/b17-10+,21-18+
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n/an/a 500n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM50316115
PNG
(3-Benzyl-6-cinnamylamino-2-methylthio-quinazolin-4...)
Show SMILES CSc1nc2ccc(NC\C=C\c3ccccc3)cc2c(=O)n1Cc1ccccc1
Show InChI InChI=1S/C25H23N3OS/c1-30-25-27-23-15-14-21(26-16-8-13-19-9-4-2-5-10-19)17-22(23)24(29)28(25)18-20-11-6-3-7-12-20/h2-15,17,26H,16,18H2,1H3/b13-8+
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n/an/a 500n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM50316130
PNG
(3-Benzyl-2-cinnamylthio-6-methyl-quinazolin-4(3H)-...)
Show SMILES Cc1ccc2nc(SC\C=C\c3ccccc3)n(Cc3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C25H22N2OS/c1-19-14-15-23-22(17-19)24(28)27(18-21-11-6-3-7-12-21)25(26-23)29-16-8-13-20-9-4-2-5-10-20/h2-15,17H,16,18H2,1H3/b13-8+
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King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM50316123
PNG
(CHEMBL1093244 | N-(3-Benzyl-2-methylthio-4-oxo-3,4...)
Show SMILES CSc1nc2ccc(NC(=O)\C=C\c3ccccc3)cc2c(=O)n1Cc1ccccc1
Show InChI InChI=1S/C25H21N3O2S/c1-31-25-27-22-14-13-20(26-23(29)15-12-18-8-4-2-5-9-18)16-21(22)24(30)28(25)17-19-10-6-3-7-11-19/h2-16H,17H2,1H3,(H,26,29)/b15-12+
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n/an/a 600n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM50316114
PNG
(3-Benzyl-6-dicinnamylamino-2-methylthio-quinazolin...)
Show SMILES CSc1nc2ccc(cc2c(=O)n1Cc1ccccc1)N(C\C=C\c1ccccc1)C\C=C\c1ccccc1
Show InChI InChI=1S/C34H31N3OS/c1-39-34-35-32-22-21-30(25-31(32)33(38)37(34)26-29-17-9-4-10-18-29)36(23-11-19-27-13-5-2-6-14-27)24-12-20-28-15-7-3-8-16-28/h2-22,25H,23-24,26H2,1H3/b19-11+,20-12+
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King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM50316120
PNG
(6-Allylamino-3-benzyl-2-methylthio-quinazolin-4(3H...)
Show SMILES CSc1nc2ccc(NCC=C)cc2c(=O)n1Cc1ccccc1
Show InChI InChI=1S/C19H19N3OS/c1-3-11-20-15-9-10-17-16(12-15)18(23)22(19(21-17)24-2)13-14-7-5-4-6-8-14/h3-10,12,20H,1,11,13H2,2H3
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King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50161264
PNG
(CHEMBL3786688)
Show SMILES COc1cc(CNC(=O)CN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc(OC)c1OC
Show InChI InChI=1S/C27H27N3O6/c1-34-21-14-18(15-22(35-2)24(21)36-3)16-28-23(31)17-30-25(32)27(29-26(30)33,19-10-6-4-7-11-19)20-12-8-5-9-13-20/h4-15H,16-17H2,1-3H3,(H,28,31)(H,29,33)
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King Saud University

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...


Eur J Med Chem 115: 121-31 (2016)


Article DOI: 10.1016/j.ejmech.2016.03.011
BindingDB Entry DOI: 10.7270/Q22N545K
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316112
PNG
(2-Allylthio-3-benzyl-6-dicinnamylamino-quinazolin-...)
Show SMILES C=CCSc1nc2ccc(cc2c(=O)n1Cc1ccccc1)N(C\C=C\c1ccccc1)C\C=C\c1ccccc1
Show InChI InChI=1S/C36H33N3OS/c1-2-26-41-36-37-34-23-22-32(27-33(34)35(40)39(36)28-31-18-10-5-11-19-31)38(24-12-20-29-14-6-3-7-15-29)25-13-21-30-16-8-4-9-17-30/h2-23,27H,1,24-26,28H2/b20-12+,21-13+
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King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM50316122
PNG
(CHEMBL1093519 | N-(2-Allylthio-3-benzyl-4-oxo-3,4-...)
Show SMILES C=CCSc1nc2ccc(NC(=O)\C=C\c3ccccc3)cc2c(=O)n1Cc1ccccc1
Show InChI InChI=1S/C27H23N3O2S/c1-2-17-33-27-29-24-15-14-22(28-25(31)16-13-20-9-5-3-6-10-20)18-23(24)26(32)30(27)19-21-11-7-4-8-12-21/h2-16,18H,1,17,19H2,(H,28,31)/b16-13+
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n/an/a 700n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50161259
PNG
(CHEMBL3785358)
Show SMILES NS(=O)(=O)c1ccc(NC(=O)CN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C23H20N4O5S/c24-33(31,32)19-13-11-18(12-14-19)25-20(28)15-27-21(29)23(26-22(27)30,16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-14H,15H2,(H,25,28)(H,26,30)(H2,24,31,32)
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King Saud University

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...


Eur J Med Chem 115: 121-31 (2016)


Article DOI: 10.1016/j.ejmech.2016.03.011
BindingDB Entry DOI: 10.7270/Q22N545K
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316120
PNG
(6-Allylamino-3-benzyl-2-methylthio-quinazolin-4(3H...)
Show SMILES CSc1nc2ccc(NCC=C)cc2c(=O)n1Cc1ccccc1
Show InChI InChI=1S/C19H19N3OS/c1-3-11-20-15-9-10-17-16(12-15)18(23)22(19(21-17)24-2)13-14-7-5-4-6-8-14/h3-10,12,20H,1,11,13H2,2H3
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n/an/a 800n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM50316118
PNG
(6-Allylamino-2-allylthio-3-benzyl-quinazolin-4(3H)...)
Show SMILES C=CCNc1ccc2nc(SCC=C)n(Cc3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C21H21N3OS/c1-3-12-22-17-10-11-19-18(14-17)20(25)24(21(23-19)26-13-4-2)15-16-8-6-5-7-9-16/h3-11,14,22H,1-2,12-13,15H2
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n/an/a 800n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316114
PNG
(3-Benzyl-6-dicinnamylamino-2-methylthio-quinazolin...)
Show SMILES CSc1nc2ccc(cc2c(=O)n1Cc1ccccc1)N(C\C=C\c1ccccc1)C\C=C\c1ccccc1
Show InChI InChI=1S/C34H31N3OS/c1-39-34-35-32-22-21-30(25-31(32)33(38)37(34)26-29-17-9-4-10-18-29)36(23-11-19-27-13-5-2-6-14-27)24-12-20-28-15-7-3-8-16-28/h2-22,25H,23-24,26H2,1H3/b19-11+,20-12+
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n/an/a 800n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316117
PNG
(2-Allylthio-3-benzyl-6-diallylamino-quinazolin-4(3...)
Show SMILES C=CCSc1nc2ccc(cc2c(=O)n1Cc1ccccc1)N(CC=C)CC=C
Show InChI InChI=1S/C24H25N3OS/c1-4-14-26(15-5-2)20-12-13-22-21(17-20)23(28)27(24(25-22)29-16-6-3)18-19-10-8-7-9-11-19/h4-13,17H,1-3,14-16,18H2
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n/an/a 900n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM50316121
PNG
(CHEMBL1089229 | N-(3-Benzyl-2-cinnamylthio-4-oxo-3...)
Show SMILES O=C(Nc1ccc2nc(SC\C=C\c3ccccc3)n(Cc3ccccc3)c(=O)c2c1)\C=C\c1ccccc1
Show InChI InChI=1S/C33H27N3O2S/c37-31(21-18-26-13-6-2-7-14-26)34-28-19-20-30-29(23-28)32(38)36(24-27-15-8-3-9-16-27)33(35-30)39-22-10-17-25-11-4-1-5-12-25/h1-21,23H,22,24H2,(H,34,37)/b17-10+,21-18+
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n/an/a 900n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50161266
PNG
(CHEMBL3786019)
Show SMILES COc1ccc(NC(=O)CCN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C25H23N3O4/c1-32-21-14-12-20(13-15-21)26-22(29)16-17-28-23(30)25(27-24(28)31,18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-15H,16-17H2,1H3,(H,26,29)(H,27,31)
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n/an/a 990n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...


Eur J Med Chem 115: 121-31 (2016)


Article DOI: 10.1016/j.ejmech.2016.03.011
BindingDB Entry DOI: 10.7270/Q22N545K
More data for this
Ligand-Target Pair
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM50316124
PNG
((E)-N-(3-Benzyl-2-cinnamylthio-4-oxo-3,4-dihydroqu...)
Show SMILES C=CC(=O)Nc1ccc2nc(SC\C=C\c3ccccc3)n(Cc3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C27H23N3O2S/c1-2-25(31)28-22-15-16-24-23(18-22)26(32)30(19-21-12-7-4-8-13-21)27(29-24)33-17-9-14-20-10-5-3-6-11-20/h2-16,18H,1,17,19H2,(H,28,31)/b14-9+
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n/an/a 1.00E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316123
PNG
(CHEMBL1093244 | N-(3-Benzyl-2-methylthio-4-oxo-3,4...)
Show SMILES CSc1nc2ccc(NC(=O)\C=C\c3ccccc3)cc2c(=O)n1Cc1ccccc1
Show InChI InChI=1S/C25H21N3O2S/c1-31-25-27-22-14-13-20(26-23(29)15-12-18-8-4-2-5-9-18)16-21(22)24(30)28(25)17-19-10-6-3-7-11-19/h2-16H,17H2,1H3,(H,26,29)/b15-12+
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King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM50316116
PNG
(6-Allyl-(methyl)-amino-3-benzyl-2-methylthioquinaz...)
Show SMILES CSc1nc2ccc(cc2c(=O)n1Cc1ccccc1)N(C)CC=C
Show InChI InChI=1S/C20H21N3OS/c1-4-12-22(2)16-10-11-18-17(13-16)19(24)23(20(21-18)25-3)14-15-8-6-5-7-9-15/h4-11,13H,1,12,14H2,2-3H3
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King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316118
PNG
(6-Allylamino-2-allylthio-3-benzyl-quinazolin-4(3H)...)
Show SMILES C=CCNc1ccc2nc(SCC=C)n(Cc3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C21H21N3OS/c1-3-12-22-17-10-11-19-18(14-17)20(25)24(21(23-19)26-13-4-2)15-16-8-6-5-7-9-16/h3-11,14,22H,1-2,12-13,15H2
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King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316119
PNG
(3-Benzyl-6-diallylamino-2-methylthio-quinazolin-4(...)
Show SMILES CSc1nc2ccc(cc2c(=O)n1Cc1ccccc1)N(CC=C)CC=C
Show InChI InChI=1S/C22H23N3OS/c1-4-13-24(14-5-2)18-11-12-20-19(15-18)21(26)25(22(23-20)27-3)16-17-9-7-6-8-10-17/h4-12,15H,1-2,13-14,16H2,3H3
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King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316130
PNG
(3-Benzyl-2-cinnamylthio-6-methyl-quinazolin-4(3H)-...)
Show SMILES Cc1ccc2nc(SC\C=C\c3ccccc3)n(Cc3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C25H22N2OS/c1-19-14-15-23-22(17-19)24(28)27(18-21-11-6-3-7-12-21)25(26-23)29-16-8-13-20-9-4-2-5-10-20/h2-15,17H,16,18H2,1H3/b13-8+
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King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50161261
PNG
(CHEMBL2139982)
Show SMILES COc1ccc(CNC(=O)CN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C25H23N3O4/c1-32-21-14-12-18(13-15-21)16-26-22(29)17-28-23(30)25(27-24(28)31,19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-15H,16-17H2,1H3,(H,26,29)(H,27,31)
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n/an/a 1.30E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...


Eur J Med Chem 115: 121-31 (2016)


Article DOI: 10.1016/j.ejmech.2016.03.011
BindingDB Entry DOI: 10.7270/Q22N545K
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50161270
PNG
(CHEMBL3786565)
Show SMILES COc1ccc(CNC(=O)CCN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C26H25N3O4/c1-33-22-14-12-19(13-15-22)18-27-23(30)16-17-29-24(31)26(28-25(29)32,20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-15H,16-18H2,1H3,(H,27,30)(H,28,32)
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n/an/a 1.32E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...


Eur J Med Chem 115: 121-31 (2016)


Article DOI: 10.1016/j.ejmech.2016.03.011
BindingDB Entry DOI: 10.7270/Q22N545K
More data for this
Ligand-Target Pair
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM50316132
PNG
(2-Allylthio-3-benzyl-6-methyl-quinazolin-4(3H)-one...)
Show SMILES Cc1ccc2nc(SCC=C)n(Cc3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C19H18N2OS/c1-3-11-23-19-20-17-10-9-14(2)12-16(17)18(22)21(19)13-15-7-5-4-6-8-15/h3-10,12H,1,11,13H2,2H3
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n/an/a 2.00E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316124
PNG
((E)-N-(3-Benzyl-2-cinnamylthio-4-oxo-3,4-dihydroqu...)
Show SMILES C=CC(=O)Nc1ccc2nc(SC\C=C\c3ccccc3)n(Cc3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C27H23N3O2S/c1-2-25(31)28-22-15-16-24-23(18-22)26(32)30(19-21-12-7-4-8-13-21)27(29-24)33-17-9-14-20-10-5-3-6-11-20/h2-16,18H,1,17,19H2,(H,28,31)/b14-9+
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King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316115
PNG
(3-Benzyl-6-cinnamylamino-2-methylthio-quinazolin-4...)
Show SMILES CSc1nc2ccc(NC\C=C\c3ccccc3)cc2c(=O)n1Cc1ccccc1
Show InChI InChI=1S/C25H23N3OS/c1-30-25-27-23-15-14-21(26-16-8-13-19-9-4-2-5-10-19)17-22(23)24(29)28(25)18-20-11-6-3-7-12-20/h2-15,17,26H,16,18H2,1H3/b13-8+
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King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316116
PNG
(6-Allyl-(methyl)-amino-3-benzyl-2-methylthioquinaz...)
Show SMILES CSc1nc2ccc(cc2c(=O)n1Cc1ccccc1)N(C)CC=C
Show InChI InChI=1S/C20H21N3OS/c1-4-12-22(2)16-10-11-18-17(13-16)19(24)23(20(21-18)25-3)14-15-8-6-5-7-9-15/h4-11,13H,1,12,14H2,2-3H3
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n/an/a 2.00E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316131
PNG
(2-Allylthio-3-benzyl-6-nitro-quinazolin-4(3H)-one ...)
Show SMILES [O-][N+](=O)c1ccc2nc(SCC=C)n(Cc3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C18H15N3O3S/c1-2-10-25-18-19-16-9-8-14(21(23)24)11-15(16)17(22)20(18)12-13-6-4-3-5-7-13/h2-9,11H,1,10,12H2
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n/an/a 2.00E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316113
PNG
(2-Allylthio-3-benzyl-6-cinnamylamino-quinazolin-4(...)
Show SMILES C=CCSc1nc2ccc(NC\C=C\c3ccccc3)cc2c(=O)n1Cc1ccccc1
Show InChI InChI=1S/C27H25N3OS/c1-2-18-32-27-29-25-16-15-23(28-17-9-14-21-10-5-3-6-11-21)19-24(25)26(31)30(27)20-22-12-7-4-8-13-22/h2-16,19,28H,1,17-18,20H2/b14-9+
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n/an/a 3.00E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316129
PNG
(3-Benzyl-2-cinnamylthio-6-nitro-quinazolin-4(3H)-o...)
Show SMILES [O-][N+](=O)c1ccc2nc(SC\C=C\c3ccccc3)n(Cc3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C24H19N3O3S/c28-23-21-16-20(27(29)30)13-14-22(21)25-24(26(23)17-19-10-5-2-6-11-19)31-15-7-12-18-8-3-1-4-9-18/h1-14,16H,15,17H2/b12-7+
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n/an/a 3.00E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316125
PNG
(3-Benzyl-1-cinnamoyl-6-methyl-2-thioxo-2,3-dihydro...)
Show SMILES Cc1ccc2n(C(O)\C=C\c3ccccc3)c(=S)n(Cc3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C25H22N2O2S/c1-18-12-14-22-21(16-18)24(29)26(17-20-10-6-3-7-11-20)25(30)27(22)23(28)15-13-19-8-4-2-5-9-19/h2-16,23,28H,17H2,1H3/b15-13+
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n/an/a 3.00E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM50316131
PNG
(2-Allylthio-3-benzyl-6-nitro-quinazolin-4(3H)-one ...)
Show SMILES [O-][N+](=O)c1ccc2nc(SCC=C)n(Cc3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C18H15N3O3S/c1-2-10-25-18-19-16-9-8-14(21(23)24)11-15(16)17(22)20(18)12-13-6-4-3-5-7-13/h2-9,11H,1,10,12H2
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n/an/a 3.00E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM50316119
PNG
(3-Benzyl-6-diallylamino-2-methylthio-quinazolin-4(...)
Show SMILES CSc1nc2ccc(cc2c(=O)n1Cc1ccccc1)N(CC=C)CC=C
Show InChI InChI=1S/C22H23N3OS/c1-4-13-24(14-5-2)18-11-12-20-19(15-18)21(26)25(22(23-20)27-3)16-17-9-7-6-8-10-17/h4-12,15H,1-2,13-14,16H2,3H3
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n/an/a 3.00E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316132
PNG
(2-Allylthio-3-benzyl-6-methyl-quinazolin-4(3H)-one...)
Show SMILES Cc1ccc2nc(SCC=C)n(Cc3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C19H18N2OS/c1-3-11-23-19-20-17-10-9-14(2)12-16(17)18(22)21(19)13-15-7-5-4-6-8-15/h3-10,12H,1,11,13H2,2H3
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n/an/a 4.00E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM50316113
PNG
(2-Allylthio-3-benzyl-6-cinnamylamino-quinazolin-4(...)
Show SMILES C=CCSc1nc2ccc(NC\C=C\c3ccccc3)cc2c(=O)n1Cc1ccccc1
Show InChI InChI=1S/C27H25N3OS/c1-2-18-32-27-29-25-16-15-23(28-17-9-14-21-10-5-3-6-11-21)19-24(25)26(31)30(27)20-22-12-7-4-8-13-22/h2-16,19,28H,1,17-18,20H2/b14-9+
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n/an/a 5.00E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316128
PNG
(2-Allylthio-6-amino-3-benzyl-quinazolin-4(3H)-one ...)
Show SMILES Nc1ccc2nc(SCC=C)n(Cc3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C18H17N3OS/c1-2-10-23-18-20-16-9-8-14(19)11-15(16)17(22)21(18)12-13-6-4-3-5-7-13/h2-9,11H,1,10,12,19H2
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n/an/a 5.00E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM50316129
PNG
(3-Benzyl-2-cinnamylthio-6-nitro-quinazolin-4(3H)-o...)
Show SMILES [O-][N+](=O)c1ccc2nc(SC\C=C\c3ccccc3)n(Cc3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C24H19N3O3S/c28-23-21-16-20(27(29)30)13-14-22(21)25-24(26(23)17-19-10-5-2-6-11-19)31-15-7-12-18-8-3-1-4-9-18/h1-14,16H,15,17H2/b12-7+
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n/an/a 5.00E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase (DHFR)


(Bos taurus (Cattle))
BDBM50316125
PNG
(3-Benzyl-1-cinnamoyl-6-methyl-2-thioxo-2,3-dihydro...)
Show SMILES Cc1ccc2n(C(O)\C=C\c3ccccc3)c(=S)n(Cc3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C25H22N2O2S/c1-18-12-14-22-21(16-18)24(29)26(17-20-10-6-3-7-11-20)25(30)27(22)23(28)15-13-19-8-4-2-5-9-19/h2-16,23,28H,17H2,1H3/b15-13+
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n/an/a 5.00E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of bovine DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (human))
BDBM50316127
PNG
(6-Amino-3-benzyl-2-cinnamylthio-quinazolin-4(3H)-o...)
Show SMILES Nc1ccc2nc(SC\C=C\c3ccccc3)n(Cc3ccccc3)c(=O)c2c1
Show InChI InChI=1S/C24H21N3OS/c25-20-13-14-22-21(16-20)23(28)27(17-19-10-5-2-6-11-19)24(26-22)29-15-7-12-18-8-3-1-4-9-18/h1-14,16H,15,17,25H2/b12-7+
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n/an/a 6.00E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of human DHFR after 2 mins


Bioorg Med Chem 18: 2849-63 (2010)


Article DOI: 10.1016/j.bmc.2010.03.019
BindingDB Entry DOI: 10.7270/Q2M61M6S
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50161258
PNG
(CHEMBL1301905)
Show SMILES COc1ccc(NC(=O)CN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C24H21N3O4/c1-31-20-14-12-19(13-15-20)25-21(28)16-27-22(29)24(26-23(27)30,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-15H,16H2,1H3,(H,25,28)(H,26,30)
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n/an/a 6.54E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...


Eur J Med Chem 115: 121-31 (2016)


Article DOI: 10.1016/j.ejmech.2016.03.011
BindingDB Entry DOI: 10.7270/Q22N545K
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (Cyclooxygenase-2)


(Ovis aries (Sheep))
BDBM50161260
PNG
(CHEMBL1702044)
Show SMILES Fc1ccc(CNC(=O)CN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C24H20FN3O3/c25-20-13-11-17(12-14-20)15-26-21(29)16-28-22(30)24(27-23(28)31,18-7-3-1-4-8-18)19-9-5-2-6-10-19/h1-14H,15-16H2,(H,26,29)(H,27,31)
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n/an/a 7.21E+3n/an/an/an/an/an/a



King Saud University

Curated by ChEMBL


Assay Description
Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...


Eur J Med Chem 115: 121-31 (2016)


Article DOI: 10.1016/j.ejmech.2016.03.011
BindingDB Entry DOI: 10.7270/Q22N545K
More data for this
Ligand-Target Pair
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