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Compile Data Set for Download or QSAR

Found 412 hits with Last Name = 'betancort' and Initial = 'jm'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM11695
PNG
((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)
Show SMILES OC12CC3CC(C1)CC(C3)(C2)NCC(=O)N1CCC[C@H]1C#N
Show InChI InChI=1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12?,13?,14-,16?,17?/m0/s1
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n/an/a 3n/an/an/an/an/an/a



Phenomix Corporation

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4 by fluorescence assay


Bioorg Med Chem Lett 19: 4437-40 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.048
BindingDB Entry DOI: 10.7270/Q2571C1Z
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50225074
PNG
((1S,3S,5S)-2-[(S)-2-amino-2-(3-hydroxy-adamantan-1...)
Show SMILES N[C@H](C(=O)N1[C@H]2C[C@H]2C[C@H]1C#N)C12CC3CC(CC(O)(C3)C1)C2
Show InChI InChI=1S/C18H25N3O2/c19-8-13-2-12-3-14(12)21(13)16(22)15(20)17-4-10-1-11(5-17)7-18(23,6-10)9-17/h10-15,23H,1-7,9,20H2/t10?,11?,12-,13+,14+,15-,17?,18?/m1/s1
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n/an/a 3n/an/an/an/an/an/a



Phenomix Corporation

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4 by fluorescence assay


Bioorg Med Chem Lett 19: 4437-40 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.048
BindingDB Entry DOI: 10.7270/Q2571C1Z
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50295970
PNG
((3R,6S,7aS)-6-amino-5-oxo-6-phenylhexahydropyrrolo...)
Show SMILES N[C@@]1(C[C@@H]2SC[C@@H](C#N)N2C1=O)c1ccccc1
Show InChI InChI=1S/C13H13N3OS/c14-7-10-8-18-11-6-13(15,12(17)16(10)11)9-4-2-1-3-5-9/h1-5,10-11H,6,8,15H2/t10-,11+,13+/m1/s1
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n/an/a 26n/an/an/an/an/an/a



Phenomix Corporation

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4 by fluorescence assay


Bioorg Med Chem Lett 19: 4437-40 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.048
BindingDB Entry DOI: 10.7270/Q2571C1Z
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50295972
PNG
((3R,6S,7aS)-6-amino-6-isopropyl-5-oxohexahydropyrr...)
Show SMILES CC(C)[C@@]1(N)C[C@@H]2SC[C@@H](C#N)N2C1=O
Show InChI InChI=1S/C10H15N3OS/c1-6(2)10(12)3-8-13(9(10)14)7(4-11)5-15-8/h6-8H,3,5,12H2,1-2H3/t7-,8+,10+/m1/s1
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n/an/a 33n/an/an/an/an/an/a



Phenomix Corporation

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4 by fluorescence assay


Bioorg Med Chem Lett 19: 4437-40 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.048
BindingDB Entry DOI: 10.7270/Q2571C1Z
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50295974
PNG
((3R,6S,7aS)-6-Amino-6-((S)-sec-butyl)-5-oxo-hexahy...)
Show SMILES CC[C@H](C)[C@@]1(N)C[C@@H]2SC[C@@H](C#N)N2C1=O
Show InChI InChI=1S/C11H17N3OS/c1-3-7(2)11(13)4-9-14(10(11)15)8(5-12)6-16-9/h7-9H,3-4,6,13H2,1-2H3/t7-,8+,9-,11-/m0/s1
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n/an/a 53n/an/an/an/an/an/a



Phenomix Corporation

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4 by fluorescence assay


Bioorg Med Chem Lett 19: 4437-40 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.048
BindingDB Entry DOI: 10.7270/Q2571C1Z
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50295971
PNG
((3R,6R,7aS)-6-amino-6-ethyl-5-oxohexahydropyrrolo[...)
Show SMILES CC[C@@]1(N)C[C@@H]2SC[C@@H](C#N)N2C1=O
Show InChI InChI=1S/C9H13N3OS/c1-2-9(11)3-7-12(8(9)13)6(4-10)5-14-7/h6-7H,2-3,5,11H2,1H3/t6-,7+,9-/m1/s1
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n/an/a 56n/an/an/an/an/an/a



Phenomix Corporation

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4 by fluorescence assay


Bioorg Med Chem Lett 19: 4437-40 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.048
BindingDB Entry DOI: 10.7270/Q2571C1Z
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50295977
PNG
((3R,6S,7aS)-6-amino-6-cyclohexyl-5-oxohexahydropyr...)
Show SMILES N[C@@]1(C[C@@H]2SC[C@@H](C#N)N2C1=O)C1CCCCC1
Show InChI InChI=1S/C13H19N3OS/c14-7-10-8-18-11-6-13(15,12(17)16(10)11)9-4-2-1-3-5-9/h9-11H,1-6,8,15H2/t10-,11+,13+/m1/s1
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n/an/a 59n/an/an/an/an/an/a



Phenomix Corporation

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4 by fluorescence assay


Bioorg Med Chem Lett 19: 4437-40 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.048
BindingDB Entry DOI: 10.7270/Q2571C1Z
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50295973
PNG
((3R,6R,7aS)-6-amino-6-isobutyl-5-oxohexahydropyrro...)
Show SMILES CC(C)C[C@@]1(N)C[C@@H]2SC[C@@H](C#N)N2C1=O
Show InChI InChI=1S/C11H17N3OS/c1-7(2)3-11(13)4-9-14(10(11)15)8(5-12)6-16-9/h7-9H,3-4,6,13H2,1-2H3/t8-,9+,11-/m1/s1
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n/an/a 63n/an/an/an/an/an/a



Phenomix Corporation

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4 by fluorescence assay


Bioorg Med Chem Lett 19: 4437-40 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.048
BindingDB Entry DOI: 10.7270/Q2571C1Z
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50295976
PNG
((3R,6S,7aS)-6-amino-6-cyclopentyl-5-oxohexahydropy...)
Show SMILES N[C@@]1(C[C@@H]2SC[C@@H](C#N)N2C1=O)C1CCCC1
Show InChI InChI=1S/C12H17N3OS/c13-6-9-7-17-10-5-12(14,11(16)15(9)10)8-3-1-2-4-8/h8-10H,1-5,7,14H2/t9-,10+,12+/m1/s1
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n/an/a 89n/an/an/an/an/an/a



Phenomix Corporation

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4 by fluorescence assay


Bioorg Med Chem Lett 19: 4437-40 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.048
BindingDB Entry DOI: 10.7270/Q2571C1Z
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50295986
PNG
((3R,6R,7aS)-6-amino-5-oxohexahydropyrrolo[2,1-b]th...)
Show SMILES N[C@@H]1C[C@@H]2SC[C@@H](C#N)N2C1=O
Show InChI InChI=1S/C7H9N3OS/c8-2-4-3-12-6-1-5(9)7(11)10(4)6/h4-6H,1,3,9H2/t4-,5-,6+/m1/s1
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n/an/a 105n/an/an/an/an/an/a



Phenomix Corporation

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4 by fluorescence assay


Bioorg Med Chem Lett 19: 4437-40 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.048
BindingDB Entry DOI: 10.7270/Q2571C1Z
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50295975
PNG
((3R,6R,7aS)-6-amino-6-benzyl-5-oxohexahydropyrrolo...)
Show SMILES N[C@]1(Cc2ccccc2)C[C@@H]2SC[C@@H](C#N)N2C1=O
Show InChI InChI=1S/C14H15N3OS/c15-8-11-9-19-12-7-14(16,13(18)17(11)12)6-10-4-2-1-3-5-10/h1-5,11-12H,6-7,9,16H2/t11-,12+,14-/m1/s1
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n/an/a 109n/an/an/an/an/an/a



Phenomix Corporation

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4 by fluorescence assay


Bioorg Med Chem Lett 19: 4437-40 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.048
BindingDB Entry DOI: 10.7270/Q2571C1Z
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50295979
PNG
((3R,6R,7aS)-6-amino-6-(cyclohexylmethyl)-5-oxohexa...)
Show SMILES N[C@]1(CC2CCCCC2)C[C@@H]2SC[C@@H](C#N)N2C1=O
Show InChI InChI=1S/C14H21N3OS/c15-8-11-9-19-12-7-14(16,13(18)17(11)12)6-10-4-2-1-3-5-10/h10-12H,1-7,9,16H2/t11-,12+,14-/m1/s1
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n/an/a 118n/an/an/an/an/an/a



Phenomix Corporation

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4 by fluorescence assay


Bioorg Med Chem Lett 19: 4437-40 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.048
BindingDB Entry DOI: 10.7270/Q2571C1Z
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50295980
PNG
((3R,6S,7aS)-6-amino-6-(4-fluorophenyl)-5-oxohexahy...)
Show SMILES N[C@@]1(C[C@@H]2SC[C@@H](C#N)N2C1=O)c1ccc(F)cc1
Show InChI InChI=1S/C13H12FN3OS/c14-9-3-1-8(2-4-9)13(16)5-11-17(12(13)18)10(6-15)7-19-11/h1-4,10-11H,5,7,16H2/t10-,11+,13+/m1/s1
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n/an/a 152n/an/an/an/an/an/a



Phenomix Corporation

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4 by fluorescence assay


Bioorg Med Chem Lett 19: 4437-40 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.048
BindingDB Entry DOI: 10.7270/Q2571C1Z
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50295978
PNG
((3R,6R,7aS)-6-amino-5-oxo-6-phenethylhexahydropyrr...)
Show SMILES N[C@]1(CCc2ccccc2)C[C@@H]2SC[C@@H](C#N)N2C1=O
Show InChI InChI=1S/C15H17N3OS/c16-9-12-10-20-13-8-15(17,14(19)18(12)13)7-6-11-4-2-1-3-5-11/h1-5,12-13H,6-8,10,17H2/t12-,13+,15-/m1/s1
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n/an/a 205n/an/an/an/an/an/a



Phenomix Corporation

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DPP4 by fluorescence assay


Bioorg Med Chem Lett 19: 4437-40 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.048
BindingDB Entry DOI: 10.7270/Q2571C1Z
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345558
PNG
(Propane-1-sulfonic acid [2-(2- chloro-6-methyl-phe...)
Show SMILES CCCS(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2Cl)n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C20H21ClN4O4S/c1-4-10-30(27,28)24-17-11-16(14-8-9-18(26)25(3)12-14)22-20(23-17)29-19-13(2)6-5-7-15(19)21/h5-9,11-12H,4,10H2,1-3H3,(H,22,23,24)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345559
PNG
(Propane-2-sulfonic acid [2-(2- chloro-6-methyl-phe...)
Show SMILES CC(C)S(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2Cl)n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C20H21ClN4O4S/c1-12(2)30(27,28)24-17-10-16(14-8-9-18(26)25(4)11-14)22-20(23-17)29-19-13(3)6-5-7-15(19)21/h5-12H,1-4H3,(H,22,23,24)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345560
PNG
(N-(2-(2,6-dimethylphenoxy)-6-(5- methoxy-1-methyl-...)
Show SMILES COc1cc(cn(C)c1=O)-c1cc(NS(=O)(=O)C(C)C)nc(Oc2c(C)cccc2C)n1
Show InChI InChI=1S/C22H26N4O5S/c1-13(2)32(28,29)25-19-11-17(16-10-18(30-6)21(27)26(5)12-16)23-22(24-19)31-20-14(3)8-7-9-15(20)4/h7-13H,1-6H3,(H,23,24,25)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345561
PNG
(N-(2-(2,6-dimethylphenoxy)-6-(5- methoxy-1-methyl-...)
Show SMILES CCCCS(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2C)n1)-c1cc(OC)c(=O)n(C)c1
Show InChI InChI=1S/C23H28N4O5S/c1-6-7-11-33(29,30)26-20-13-18(17-12-19(31-5)22(28)27(4)14-17)24-23(25-20)32-21-15(2)9-8-10-16(21)3/h8-10,12-14H,6-7,11H2,1-5H3,(H,24,25,26)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345562
PNG
(Propane-1-sulfonic acid [6-(2- chloro-6-methyl-phe...)
Show SMILES CCCS(=O)(=O)Nc1cc(Oc2c(C)cccc2Cl)nc(n1)-c1cc(C)c(=O)n(C)c1
Show InChI InChI=1S/C21H23ClN4O4S/c1-5-9-31(28,29)25-17-11-18(30-19-13(2)7-6-8-16(19)22)24-20(23-17)15-10-14(3)21(27)26(4)12-15/h6-8,10-12H,5,9H2,1-4H3,(H,23,24,25)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345563
PNG
(Butane-1-sulfonic acid [2-(2-cyano- 6-methyl-pheno...)
Show SMILES CCCCS(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2C#N)n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C22H23N5O4S/c1-4-5-11-32(29,30)26-19-12-18(17-9-10-20(28)27(3)14-17)24-22(25-19)31-21-15(2)7-6-8-16(21)13-23/h6-10,12,14H,4-5,11H2,1-3H3,(H,24,25,26)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345564
PNG
(Propane-1-sulfonic acid [2-(2- cyano-6-methyl-phen...)
Show SMILES CCCS(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2C#N)n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C21H21N5O4S/c1-4-10-31(28,29)25-18-11-17(16-8-9-19(27)26(3)13-16)23-21(24-18)30-20-14(2)6-5-7-15(20)12-22/h5-9,11,13H,4,10H2,1-3H3,(H,23,24,25)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345565
PNG
(Propane-2-sulfonic acid [2-(2- cyano-6-methyl-phen...)
Show SMILES CC(C)S(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2C#N)n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C21H21N5O4S/c1-13(2)31(28,29)25-18-10-17(16-8-9-19(27)26(4)12-16)23-21(24-18)30-20-14(3)6-5-7-15(20)11-22/h5-10,12-13H,1-4H3,(H,23,24,25)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345567
PNG
(Propane-1-sulfonic acid [6-(1,5- dimethyl-6-oxo-1,...)
Show SMILES CCCS(=O)(=O)Nc1cc(nc(Oc2cnccc2C)n1)-c1cc(C)c(=O)n(C)c1
Show InChI InChI=1S/C20H23N5O4S/c1-5-8-30(27,28)24-18-10-16(15-9-14(3)19(26)25(4)12-15)22-20(23-18)29-17-11-21-7-6-13(17)2/h6-7,9-12H,5,8H2,1-4H3,(H,22,23,24)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345568
PNG
(Butane-1-sulfonic acid [2-(2-fluoro- 6-methyl-phen...)
Show SMILES CCCCS(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2F)n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C21H23FN4O4S/c1-4-5-11-31(28,29)25-18-12-17(15-9-10-19(27)26(3)13-15)23-21(24-18)30-20-14(2)7-6-8-16(20)22/h6-10,12-13H,4-5,11H2,1-3H3,(H,23,24,25)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345569
PNG
(Butane-1-sulfonic acid [6-(5-chloro- 1-methyl-6-ox...)
Show SMILES CCCCS(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2C#N)n1)-c1cc(Cl)c(=O)n(C)c1
Show InChI InChI=1S/C22H22ClN5O4S/c1-4-5-9-33(30,31)27-19-11-18(16-10-17(23)21(29)28(3)13-16)25-22(26-19)32-20-14(2)7-6-8-15(20)12-24/h6-8,10-11,13H,4-5,9H2,1-3H3,(H,25,26,27)
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CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345570
PNG
(3-Fluoro-propane-1-sulfonic acid [2- (2-cyano-6-me...)
Show SMILES Cc1cccc(C#N)c1Oc1nc(NS(=O)(=O)CCCF)cc(n1)-c1cc(C)c(=O)n(C)c1
Show InChI InChI=1S/C22H22FN5O4S/c1-14-6-4-7-16(12-24)20(14)32-22-25-18(17-10-15(2)21(29)28(3)13-17)11-19(26-22)27-33(30,31)9-5-8-23/h4,6-7,10-11,13H,5,8-9H2,1-3H3,(H,25,26,27)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345571
PNG
(Ethanesulfonic acid [2-(2-fluoro-6- methyl-phenoxy...)
Show SMILES CCS(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2F)n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C19H19FN4O4S/c1-4-29(26,27)23-16-10-15(13-8-9-17(25)24(3)11-13)21-19(22-16)28-18-12(2)6-5-7-14(18)20/h5-11H,4H2,1-3H3,(H,21,22,23)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345572
PNG
(Propane-2-sulfonic acid [6-(5- chloro-1-methyl-6-o...)
Show SMILES CC(C)S(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2F)n1)-c1cc(Cl)c(=O)n(C)c1
Show InChI InChI=1S/C20H20ClFN4O4S/c1-11(2)31(28,29)25-17-9-16(13-8-14(21)19(27)26(4)10-13)23-20(24-17)30-18-12(3)6-5-7-15(18)22/h5-11H,1-4H3,(H,23,24,25)
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CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345573
PNG
(Propane-2-sulfonic acid [6-(5- chloro-1-methyl-6-o...)
Show SMILES CC(C)S(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2Cl)n1)-c1cc(Cl)c(=O)n(C)c1
Show InChI InChI=1S/C20H20Cl2N4O4S/c1-11(2)31(28,29)25-17-9-16(13-8-15(22)19(27)26(4)10-13)23-20(24-17)30-18-12(3)6-5-7-14(18)21/h5-11H,1-4H3,(H,23,24,25)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345574
PNG
(Propane-2-sulfonic acid [2-(2- fluoro-6-methyl-phe...)
Show SMILES CC(C)S(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2F)n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C20H21FN4O4S/c1-12(2)30(27,28)24-17-10-16(14-8-9-18(26)25(4)11-14)22-20(23-17)29-19-13(3)6-5-7-15(19)21/h5-12H,1-4H3,(H,22,23,24)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345575
PNG
(Propane-1-sulfonic acid [2-(2- fluoro-6-methyl-phe...)
Show SMILES CCCS(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2F)n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C20H21FN4O4S/c1-4-10-30(27,28)24-17-11-16(14-8-9-18(26)25(3)12-14)22-20(23-17)29-19-13(2)6-5-7-15(19)21/h5-9,11-12H,4,10H2,1-3H3,(H,22,23,24)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345576
PNG
(Butane-1-sulfonic acid [6-(5-chloro- 1-methyl-6-ox...)
Show SMILES CCCCS(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2Cl)n1)-c1cc(Cl)c(=O)n(C)c1
Show InChI InChI=1S/C21H22Cl2N4O4S/c1-4-5-9-32(29,30)26-18-11-17(14-10-16(23)20(28)27(3)12-14)24-21(25-18)31-19-13(2)7-6-8-15(19)22/h6-8,10-12H,4-5,9H2,1-3H3,(H,24,25,26)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345577
PNG
(Butane-1-sulfonic acid [6-(5-chloro- 1-methyl-6-ox...)
Show SMILES CCCCS(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2F)n1)-c1cc(Cl)c(=O)n(C)c1
Show InChI InChI=1S/C21H22ClFN4O4S/c1-4-5-9-32(29,30)26-18-11-17(14-10-15(22)20(28)27(3)12-14)24-21(25-18)31-19-13(2)7-6-8-16(19)23/h6-8,10-12H,4-5,9H2,1-3H3,(H,24,25,26)
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CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345578
PNG
(3-Fluoro-propane-1-sulfonic acid [2- (2-cyano-6-me...)
Show SMILES Cc1cccc(C#N)c1Oc1nc(NS(=O)(=O)CCCF)cc(n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C21H20FN5O4S/c1-14-5-3-6-15(12-23)20(14)31-21-24-17(16-7-8-19(28)27(2)13-16)11-18(25-21)26-32(29,30)10-4-9-22/h3,5-8,11,13H,4,9-10H2,1-2H3,(H,24,25,26)
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CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345579
PNG
(Butane-1-sulfonic acid [6-(1-methyl- 6-oxo-1,6-dih...)
Show SMILES CCCCS(=O)(=O)Nc1cc(nc(Oc2c(C)nn(C)c2C)n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C20H26N6O4S/c1-6-7-10-31(28,29)24-17-11-16(15-8-9-18(27)25(4)12-15)21-20(22-17)30-19-13(2)23-26(5)14(19)3/h8-9,11-12H,6-7,10H2,1-5H3,(H,21,22,24)
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CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345580
PNG
(Propane-2-sulfonic acid [6-(1- methyl-6-oxo-1,6-di...)
Show SMILES CC(C)S(=O)(=O)Nc1cc(nc(Oc2c(C)nn(C)c2C)n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C19H24N6O4S/c1-11(2)30(27,28)23-16-9-15(14-7-8-17(26)24(5)10-14)20-19(21-16)29-18-12(3)22-25(6)13(18)4/h7-11H,1-6H3,(H,20,21,23)
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CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345581
PNG
(Propane-1-sulfonic acid [6-(1- methyl-6-oxo-1,6-di...)
Show SMILES CCCS(=O)(=O)Nc1cc(nc(Oc2c(C)nn(C)c2C)n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C19H24N6O4S/c1-6-9-30(27,28)23-16-10-15(14-7-8-17(26)24(4)11-14)20-19(21-16)29-18-12(2)22-25(5)13(18)3/h7-8,10-11H,6,9H2,1-5H3,(H,20,21,23)
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CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345582
PNG
(Propane-2-sulfonic acid [6-(1,5- dimethyl-6-oxo-1,...)
Show SMILES CCn1nc(C)c(Oc2nc(NS(=O)(=O)C(C)C)cc(n2)-c2cc(C)c(=O)n(C)c2)c1C
Show InChI InChI=1S/C21H28N6O4S/c1-8-27-15(6)19(14(5)24-27)31-21-22-17(16-9-13(4)20(28)26(7)11-16)10-18(23-21)25-32(29,30)12(2)3/h9-12H,8H2,1-7H3,(H,22,23,25)
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CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345583
PNG
(Butane-1-sulfonic acid [6-(1,5- dimethyl-6-oxo-1,6...)
Show SMILES CCCCS(=O)(=O)Nc1cc(nc(Oc2c(C)nn(CC)c2C)n1)-c1cc(C)c(=O)n(C)c1
Show InChI InChI=1S/C22H30N6O4S/c1-7-9-10-33(30,31)26-19-12-18(17-11-14(3)21(29)27(6)13-17)23-22(24-19)32-20-15(4)25-28(8-2)16(20)5/h11-13H,7-10H2,1-6H3,(H,23,24,26)
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CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345584
PNG
(Propane-1-sulfonic acid [6-(2- cyano-6-methyl-phen...)
Show SMILES CCCS(=O)(=O)Nc1cc(Oc2c(C)cccc2C#N)nc(n1)-c1cc(C)c(=O)n(C)c1
Show InChI InChI=1S/C22H23N5O4S/c1-5-9-32(29,30)26-18-11-19(31-20-14(2)7-6-8-16(20)12-23)25-21(24-18)17-10-15(3)22(28)27(4)13-17/h6-8,10-11,13H,5,9H2,1-4H3,(H,24,25,26)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345585
PNG
(Propane-1-sulfonic acid [6-(2- cyano-6-methoxy-phe...)
Show SMILES CCCS(=O)(=O)Nc1cc(Oc2c(OC)cccc2C#N)nc(n1)-c1cc(C)c(=O)n(C)c1
Show InChI InChI=1S/C22H23N5O5S/c1-5-9-33(29,30)26-18-11-19(32-20-15(12-23)7-6-8-17(20)31-4)25-21(24-18)16-10-14(2)22(28)27(3)13-16/h6-8,10-11,13H,5,9H2,1-4H3,(H,24,25,26)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345586
PNG
(Ethanesulfonic acid [2- cyclopentyloxy-6-(1,5-dime...)
Show SMILES CCS(=O)(=O)Nc1cc(nc(OC2CCCC2)n1)-c1cc(C)c(=O)n(C)c1
Show InChI InChI=1S/C18H24N4O4S/c1-4-27(24,25)21-16-10-15(13-9-12(2)17(23)22(3)11-13)19-18(20-16)26-14-7-5-6-8-14/h9-11,14H,4-8H2,1-3H3,(H,19,20,21)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345587
PNG
(5-[2-(2,4-Difluoro-phenoxy)-6- methanesulfonyl-pyr...)
Show SMILES Cc1cc(cn(C)c1=O)-c1cc(nc(Oc2ccc(F)cc2F)n1)S(C)(=O)=O
Show InChI InChI=1S/C18H15F2N3O4S/c1-10-6-11(9-23(2)17(10)24)14-8-16(28(3,25)26)22-18(21-14)27-15-5-4-12(19)7-13(15)20/h4-9H,1-3H3
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345588
PNG
(5-[2-(2-Chloro-6-methyl-phenoxy)- 6-methanesulfony...)
Show SMILES Cc1cccc(C#N)c1Oc1nc(cc(n1)S(C)(=O)=O)-c1cc(C)c(=O)n(C)c1
Show InChI InChI=1S/C20H18N4O4S/c1-12-6-5-7-14(10-21)18(12)28-20-22-16(9-17(23-20)29(4,26)27)15-8-13(2)19(25)24(3)11-15/h5-9,11H,1-4H3
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345589
PNG
(5-[2-(2,4-Difluoro-phenoxy)-6- (propane-2-sulfonyl...)
Show SMILES CC(C)S(=O)(=O)c1cc(nc(Oc2ccc(F)cc2F)n1)-c1cc(C)c(=O)n(C)c1
Show InChI InChI=1S/C20H19F2N3O4S/c1-11(2)30(27,28)18-9-16(13-7-12(3)19(26)25(4)10-13)23-20(24-18)29-17-6-5-14(21)8-15(17)22/h5-11H,1-4H3
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345590
PNG
(5-[2-(2-Chloro-6-methyl-phenoxy)- 6-(propane-2-sul...)
Show SMILES CC(C)S(=O)(=O)c1cc(nc(Oc2c(C)cccc2Cl)n1)-c1cc(C)c(=O)n(C)c1
Show InChI InChI=1S/C21H22ClN3O4S/c1-12(2)30(27,28)18-10-17(15-9-14(4)20(26)25(5)11-15)23-21(24-18)29-19-13(3)7-6-8-16(19)22/h6-12H,1-5H3
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345591
PNG
(3-Fluoro-propane-1-sulfonic acid [2- (2-fluoro-6-m...)
Show SMILES Cc1cccc(F)c1Oc1nc(NS(=O)(=O)CCCF)cc(n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C20H20F2N4O4S/c1-13-5-3-6-15(22)19(13)30-20-23-16(14-7-8-18(27)26(2)12-14)11-17(24-20)25-31(28,29)10-4-9-21/h3,5-8,11-12H,4,9-10H2,1-2H3,(H,23,24,25)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345592
PNG
(Butane-2-sulfonic acid [2-(2-fluoro- 6-methyl-phen...)
Show SMILES CCC(C)S(=O)(=O)Nc1cc(nc(Oc2c(C)cccc2F)n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C21H23FN4O4S/c1-5-14(3)31(28,29)25-18-11-17(15-9-10-19(27)26(4)12-15)23-21(24-18)30-20-13(2)7-6-8-16(20)22/h6-12,14H,5H2,1-4H3,(H,23,24,25)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345593
PNG
(Butane-1-sulfonic acid [2-(2-chloro- 6-fluoro-phen...)
Show SMILES CCCCS(=O)(=O)Nc1cc(nc(Oc2c(F)cccc2Cl)n1)-c1cc(C)c(=O)n(C)c1
Show InChI InChI=1S/C21H22ClFN4O4S/c1-4-5-9-32(29,30)26-18-11-17(14-10-13(2)20(28)27(3)12-14)24-21(25-18)31-19-15(22)7-6-8-16(19)23/h6-8,10-12H,4-5,9H2,1-3H3,(H,24,25,26)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
CREB-binding protein


(Homo sapiens (Human))
BDBM345594
PNG
(Butane-1-sulfonic acid [2-(2-chloro- 6-fluoro-phen...)
Show SMILES CCCCS(=O)(=O)Nc1cc(nc(Oc2c(F)cccc2Cl)n1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C20H20ClFN4O4S/c1-3-4-10-31(28,29)25-17-11-16(13-8-9-18(27)26(2)12-13)23-20(24-17)30-19-14(21)6-5-7-15(19)22/h5-9,11-12H,3-4,10H2,1-2H3,(H,23,24,25)
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n/an/a<500n/an/an/an/an/an/a



CELGENE QUANTICEL RESEARCH, INC.

US Patent


Assay Description
Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...


US Patent US10202360 (2019)


Article DOI: 10.1021/jm060653b
More data for this
Ligand-Target Pair
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