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Compile Data Set for Download or QSAR

Found 160 hits with Last Name = 'choi' and Initial = 'jw'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384024
PNG
(CHEMBL2032280 | CHEMBL2079349)
Show SMILES Cc1c(O)ccc2nc(oc12)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C21H22N6O2/c1-12-18(28)3-2-17-19(12)29-21(26-17)16-8-13(9-24-20(16)22)14-10-25-27(11-14)15-4-6-23-7-5-15/h2-3,8-11,15,23,28H,4-7H2,1H3,(H2,22,24)
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n/an/a 0.200n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50380974
PNG
(CHEMBL2016903)
Show SMILES Fc1ccc2[nH]c(=O)c(cc2c1)-c1nc2CCN(Cc2[nH]1)C(=O)c1ccncc1
Show InChI InChI=1S/C21H16FN5O2/c22-14-1-2-16-13(9-14)10-15(20(28)26-16)19-24-17-5-8-27(11-18(17)25-19)21(29)12-3-6-23-7-4-12/h1-4,6-7,9-10H,5,8,11H2,(H,24,25)(H,26,28)
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n/an/a 0.300n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50380971
PNG
(CHEMBL2016927)
Show SMILES Clc1ccc2[nH]c(=O)c(cc2c1)-c1nc2CCN(Cc2[nH]1)C(=O)Cc1ccncc1
Show InChI InChI=1S/C22H18ClN5O2/c23-15-1-2-17-14(10-15)11-16(22(30)27-17)21-25-18-5-8-28(12-19(18)26-21)20(29)9-13-3-6-24-7-4-13/h1-4,6-7,10-11H,5,8-9,12H2,(H,25,26)(H,27,30)
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n/an/a 0.5n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM50384038
PNG
(CHEMBL2032155)
Show SMILES Nc1ncc(cc1-c1nc2cccc(-c3ccccn3)c2o1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C25H23N7O/c26-24-20(12-16(13-29-24)17-14-30-32(15-17)18-7-10-27-11-8-18)25-31-22-6-3-4-19(23(22)33-25)21-5-1-2-9-28-21/h1-6,9,12-15,18,27H,7-8,10-11H2,(H2,26,29)
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n/an/a 0.600n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50380968
PNG
(CHEMBL2016924)
Show SMILES Fc1ccc2[nH]c(=O)c(cc2c1)-c1nc2CCN(Cc2[nH]1)C(=O)Cc1ccccn1
Show InChI InChI=1S/C22H18FN5O2/c23-14-4-5-17-13(9-14)10-16(22(30)27-17)21-25-18-6-8-28(12-19(18)26-21)20(29)11-15-3-1-2-7-24-15/h1-5,7,9-10H,6,8,11-12H2,(H,25,26)(H,27,30)
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n/an/a 0.700n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50380946
PNG
(CHEMBL2016900)
Show SMILES Fc1ccc2[nH]c(=O)c(cc2c1)-c1nc2CCN(Cc2[nH]1)C(=O)c1cccnc1
Show InChI InChI=1S/C21H16FN5O2/c22-14-3-4-16-13(8-14)9-15(20(28)26-16)19-24-17-5-7-27(11-18(17)25-19)21(29)12-2-1-6-23-10-12/h1-4,6,8-10H,5,7,11H2,(H,24,25)(H,26,28)
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n/an/a 1n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50380967
PNG
(CHEMBL2016923)
Show SMILES O=C(Cc1ccccn1)N1CCc2nc([nH]c2C1)-c1cc2ccccc2[nH]c1=O
Show InChI InChI=1S/C22H19N5O2/c28-20(12-15-6-3-4-9-23-15)27-10-8-18-19(13-27)25-21(24-18)16-11-14-5-1-2-7-17(14)26-22(16)29/h1-7,9,11H,8,10,12-13H2,(H,24,25)(H,26,29)
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n/an/a 1.30n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50380949
PNG
(CHEMBL2016904)
Show SMILES O=C(N1CCc2nc([nH]c2C1)-c1cc2ccccc2[nH]c1=O)c1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C28H29N5O2/c34-27-22(16-21-6-2-3-7-23(21)31-27)26-29-24-12-15-33(18-25(24)30-26)28(35)20-10-8-19(9-11-20)17-32-13-4-1-5-14-32/h2-3,6-11,16H,1,4-5,12-15,17-18H2,(H,29,30)(H,31,34)
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n/an/a 1.30n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384038
PNG
(CHEMBL2032155)
Show SMILES Nc1ncc(cc1-c1nc2cccc(-c3ccccn3)c2o1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C25H23N7O/c26-24-20(12-16(13-29-24)17-14-30-32(15-17)18-7-10-27-11-8-18)25-31-22-6-3-4-19(23(22)33-25)21-5-1-2-9-28-21/h1-6,9,12-15,18,27H,7-8,10-11H2,(H2,26,29)
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n/an/a 1.60n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM50384004
PNG
(CHEMBL2032276)
Show SMILES Cc1cc2oc(nc2cc1O)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C21H22N6O2/c1-12-6-19-17(8-18(12)28)26-21(29-19)16-7-13(9-24-20(16)22)14-10-25-27(11-14)15-2-4-23-5-3-15/h6-11,15,23,28H,2-5H2,1H3,(H2,22,24)
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n/an/a 2n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50380972
PNG
(CHEMBL2016928)
Show SMILES Cc1cccc(NC(=O)N2CCc3nc([nH]c3C2)-c2cc3ccccc3[nH]c2=O)c1
Show InChI InChI=1S/C23H21N5O2/c1-14-5-4-7-16(11-14)24-23(30)28-10-9-19-20(13-28)26-21(25-19)17-12-15-6-2-3-8-18(15)27-22(17)29/h2-8,11-12H,9-10,13H2,1H3,(H,24,30)(H,25,26)(H,27,29)
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n/an/a 2.10n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384027
PNG
(CHEMBL2032277)
Show SMILES Cc1cc2oc(nc2c(C)c1O)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C22H24N6O2/c1-12-7-18-19(13(2)20(12)29)27-22(30-18)17-8-14(9-25-21(17)23)15-10-26-28(11-15)16-3-5-24-6-4-16/h7-11,16,24,29H,3-6H2,1-2H3,(H2,23,25)
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n/an/a 3n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM50384019
PNG
(CHEMBL2032285 | CHEMBL2079397)
Show SMILES Nc1ccc2nc(oc2c1)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C20H21N7O/c21-14-1-2-17-18(8-14)28-20(26-17)16-7-12(9-24-19(16)22)13-10-25-27(11-13)15-3-5-23-6-4-15/h1-2,7-11,15,23H,3-6,21H2,(H2,22,24)
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n/an/a 3.60n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM50384006
PNG
(CHEMBL2032274)
Show SMILES Nc1ncc(cc1-c1nc2ccc(O)cc2o1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C20H20N6O2/c21-19-16(20-25-17-2-1-15(27)8-18(17)28-20)7-12(9-23-19)13-10-24-26(11-13)14-3-5-22-6-4-14/h1-2,7-11,14,22,27H,3-6H2,(H2,21,23)
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n/an/a 4n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM50384026
PNG
(CHEMBL2032278)
Show SMILES CCc1cc2oc(nc2cc1O)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C22H24N6O2/c1-2-13-8-20-18(9-19(13)29)27-22(30-20)17-7-14(10-25-21(17)23)15-11-26-28(12-15)16-3-5-24-6-4-16/h7-12,16,24,29H,2-6H2,1H3,(H2,23,25)
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n/an/a 4n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384023
PNG
(CHEMBL2032281)
Show SMILES Nc1ncc(cc1-c1nc2ccc(O)c(-c3cccnc3)c2o1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C25H23N7O2/c26-24-19(10-16(12-29-24)17-13-30-32(14-17)18-5-8-27-9-6-18)25-31-20-3-4-21(33)22(23(20)34-25)15-2-1-7-28-11-15/h1-4,7,10-14,18,27,33H,5-6,8-9H2,(H2,26,29)
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n/an/a 4n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50380954
PNG
(CHEMBL2016909)
Show SMILES Fc1ccc2[nH]c(=O)c(cc2c1)-c1nc2CCN(Cc2[nH]1)C(=O)CN1CCOCC1
Show InChI InChI=1S/C21H22FN5O3/c22-14-1-2-16-13(9-14)10-15(21(29)25-16)20-23-17-3-4-27(11-18(17)24-20)19(28)12-26-5-7-30-8-6-26/h1-2,9-10H,3-8,11-12H2,(H,23,24)(H,25,29)
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n/an/a 4.30n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50380950
PNG
(CHEMBL2016905)
Show SMILES Fc1ccc2[nH]c(=O)c(cc2c1)-c1nc2CCN(Cc2[nH]1)C(=O)c1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C28H28FN5O2/c29-21-8-9-23-20(14-21)15-22(27(35)32-23)26-30-24-10-13-34(17-25(24)31-26)28(36)19-6-4-18(5-7-19)16-33-11-2-1-3-12-33/h4-9,14-15H,1-3,10-13,16-17H2,(H,30,31)(H,32,35)
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n/an/a 4.90n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50380969
PNG
(CHEMBL2016925)
Show SMILES O=C(Cc1ccncc1)N1CCc2nc([nH]c2C1)-c1cc2ccccc2[nH]c1=O
Show InChI InChI=1S/C22H19N5O2/c28-20(11-14-5-8-23-9-6-14)27-10-7-18-19(13-27)25-21(24-18)16-12-15-3-1-2-4-17(15)26-22(16)29/h1-6,8-9,12H,7,10-11,13H2,(H,24,25)(H,26,29)
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n/an/a 6.70n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM5328
PNG
(2-quinolinone deriv. 3 | 3-(1H-indol-2-yl)-1,2-dih...)
Show SMILES O=c1[nH]c2ccccc2cc1-c1cc2ccccc2[nH]1
Show InChI InChI=1S/C17H12N2O/c20-17-13(9-11-5-1-4-8-15(11)19-17)16-10-12-6-2-3-7-14(12)18-16/h1-10,18H,(H,19,20)
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n/an/a 8n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of VEGFR-2 kinase


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM15581
PNG
(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C
Show InChI InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3
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n/an/a 8n/an/an/an/an/an/a



Korea Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human MAOA using p-tyramine as substrate after 30 mins by Amplex red based spectrophotometric analysis


Bioorg Med Chem 23: 6486-96 (2015)


Article DOI: 10.1016/j.bmc.2015.08.012
BindingDB Entry DOI: 10.7270/Q2MK6FPP
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50380964
PNG
(CHEMBL2016919)
Show SMILES Fc1ccc2[nH]c(=O)c(cc2c1)-c1nc2CCN(Cc2[nH]1)C(=O)CN1CCCCC1
Show InChI InChI=1S/C22H24FN5O2/c23-15-4-5-17-14(10-15)11-16(22(30)26-17)21-24-18-6-9-28(12-19(18)25-21)20(29)13-27-7-2-1-3-8-27/h4-5,10-11H,1-3,6-9,12-13H2,(H,24,25)(H,26,30)
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n/an/a 8n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384022
PNG
(CHEMBL2032282)
Show SMILES Nc1ncc(cc1-c1nc2ccc(O)c(-c3cnccn3)c2o1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C24H22N8O2/c25-23-17(9-14(10-29-23)15-11-30-32(13-15)16-3-5-26-6-4-16)24-31-18-1-2-20(33)21(22(18)34-24)19-12-27-7-8-28-19/h1-2,7-13,16,26,33H,3-6H2,(H2,25,29)
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n/an/a 8n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50380970
PNG
(CHEMBL2016926)
Show SMILES Fc1ccc2[nH]c(=O)c(cc2c1)-c1nc2CCN(Cc2[nH]1)C(=O)Cc1ccncc1
Show InChI InChI=1S/C22H18FN5O2/c23-15-1-2-17-14(10-15)11-16(22(30)27-17)21-25-18-5-8-28(12-19(18)26-21)20(29)9-13-3-6-24-7-4-13/h1-4,6-7,10-11H,5,8-9,12H2,(H,25,26)(H,27,30)
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n/an/a 8.60n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM15579
PNG
(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C
Show InChI InChI=1/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/s2
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n/an/a 9n/an/an/an/an/an/a



Korea Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human MAOB using benzylamine as substrate after 30 mins by Amplex red based spectrophotometric analysis


Bioorg Med Chem 23: 6486-96 (2015)


Article DOI: 10.1016/j.bmc.2015.08.012
BindingDB Entry DOI: 10.7270/Q2MK6FPP
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384026
PNG
(CHEMBL2032278)
Show SMILES CCc1cc2oc(nc2cc1O)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C22H24N6O2/c1-2-13-8-20-18(9-19(13)29)27-22(30-20)17-7-14(10-25-21(17)23)15-11-26-28(12-15)16-3-5-24-6-4-16/h7-12,16,24,29H,2-6H2,1H3,(H2,23,25)
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n/an/a 9n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50380959
PNG
(CHEMBL2016914)
Show SMILES CN1CCN(CC(=O)N2CCc3nc([nH]c3C2)-c2cc3cc(F)ccc3[nH]c2=O)CC1
Show InChI InChI=1S/C22H25FN6O2/c1-27-6-8-28(9-7-27)13-20(30)29-5-4-18-19(12-29)25-21(24-18)16-11-14-10-15(23)2-3-17(14)26-22(16)31/h2-3,10-11H,4-9,12-13H2,1H3,(H,24,25)(H,26,31)
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n/an/a 13n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM50384021
PNG
(CHEMBL2032283 | CHEMBL2079205)
Show SMILES Nc1ncc(cc1-c1nc2ccc(O)c(-c3ccccc3)c2o1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C26H24N6O2/c27-25-20(12-17(13-29-25)18-14-30-32(15-18)19-8-10-28-11-9-19)26-31-21-6-7-22(33)23(24(21)34-26)16-4-2-1-3-5-16/h1-7,12-15,19,28,33H,8-11H2,(H2,27,29)
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n/an/a 14n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384045
PNG
(CHEMBL2032298)
Show SMILES Cn1cc(cn1)-c1cnc(N)c(c1)-c1nc2cccc(-c3ccccn3)c2o1
Show InChI InChI=1S/C21H16N6O/c1-27-12-14(11-25-27)13-9-16(20(22)24-10-13)21-26-18-7-4-5-15(19(18)28-21)17-6-2-3-8-23-17/h2-12H,1H3,(H2,22,24)
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n/an/a 14n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Macrophage-stimulating protein receptor


(Homo sapiens (Human))
BDBM50384006
PNG
(CHEMBL2032274)
Show SMILES Nc1ncc(cc1-c1nc2ccc(O)cc2o1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C20H20N6O2/c21-19-16(20-25-17-2-1-15(27)8-18(17)28-20)7-12(9-23-19)13-10-24-26(11-13)14-3-5-22-6-4-14/h1-2,7-11,14,22,27H,3-6H2,(H2,21,23)
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n/an/a 14n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of Ron


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384019
PNG
(CHEMBL2032285 | CHEMBL2079397)
Show SMILES Nc1ccc2nc(oc2c1)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C20H21N7O/c21-14-1-2-17-18(8-14)28-20(26-17)16-7-12(9-24-19(16)22)13-10-25-27(11-13)15-3-5-23-6-4-15/h1-2,7-11,15,23H,3-6,21H2,(H2,22,24)
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n/an/a 14n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM152636
PNG
((2E)-1-(4-methoxyphenyl)-3-[2-(trifluoromethyl)phe...)
Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccccc1C(F)(F)F
Show InChI InChI=1S/C17H13F3O2/c1-22-14-9-6-13(7-10-14)16(21)11-8-12-4-2-3-5-15(12)17(18,19)20/h2-11H,1H3/b11-8+
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n/an/a 16n/an/an/an/an/an/a



Korea Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human MAOB using benzylamine as substrate after 30 mins by Amplex red based spectrophotometric analysis


Bioorg Med Chem 23: 6486-96 (2015)


Article DOI: 10.1016/j.bmc.2015.08.012
BindingDB Entry DOI: 10.7270/Q2MK6FPP
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50380962
PNG
(CHEMBL2016917)
Show SMILES O=C(CN1CCCCC1)N1CCc2nc([nH]c2C1)-c1cc2ccccc2[nH]c1=O
Show InChI InChI=1S/C22H25N5O2/c28-20(14-26-9-4-1-5-10-26)27-11-8-18-19(13-27)24-21(23-18)16-12-15-6-2-3-7-17(15)25-22(16)29/h2-3,6-7,12H,1,4-5,8-11,13-14H2,(H,23,24)(H,25,29)
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n/an/a 16n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50380960
PNG
(CHEMBL2016915)
Show SMILES CN1CCN(CC(=O)N2CCc3nc([nH]c3C2)-c2cc3cc(Cl)ccc3[nH]c2=O)CC1
Show InChI InChI=1S/C22H25ClN6O2/c1-27-6-8-28(9-7-27)13-20(30)29-5-4-18-19(12-29)25-21(24-18)16-11-14-10-15(23)2-3-17(14)26-22(16)31/h2-3,10-11H,4-9,12-13H2,1H3,(H,24,25)(H,26,31)
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n/an/a 19n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384006
PNG
(CHEMBL2032274)
Show SMILES Nc1ncc(cc1-c1nc2ccc(O)cc2o1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C20H20N6O2/c21-19-16(20-25-17-2-1-15(27)8-18(17)28-20)7-12(9-23-19)13-10-24-26(11-13)14-3-5-22-6-4-14/h1-2,7-11,14,22,27H,3-6H2,(H2,21,23)
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n/an/a 19n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384029
PNG
(CHEMBL2032273)
Show SMILES Nc1ncc(cc1-c1nc2cc(O)ccc2o1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C20H20N6O2/c21-19-16(20-25-17-8-15(27)1-2-18(17)28-20)7-12(9-23-19)13-10-24-26(11-13)14-3-5-22-6-4-14/h1-2,7-11,14,22,27H,3-6H2,(H2,21,23)
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n/an/a 22n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50380965
PNG
(CHEMBL2016920)
Show SMILES Clc1ccc2[nH]c(=O)c(cc2c1)-c1nc2CCN(Cc2[nH]1)C(=O)CN1CCCCC1
Show InChI InChI=1S/C22H24ClN5O2/c23-15-4-5-17-14(10-15)11-16(22(30)26-17)21-24-18-6-9-28(12-19(18)25-21)20(29)13-27-7-2-1-3-8-27/h4-5,10-11H,1-3,6-9,12-13H2,(H,24,25)(H,26,30)
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n/an/a 22n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384030
PNG
(CHEMBL2032272 | CHEMBL2079392)
Show SMILES Nc1ncc(cc1-c1nc2ccc(Oc3ncccn3)cc2o1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C24H22N8O2/c25-22-19(10-15(12-29-22)16-13-30-32(14-16)17-4-8-26-9-5-17)23-31-20-3-2-18(11-21(20)34-23)33-24-27-6-1-7-28-24/h1-3,6-7,10-14,17,26H,4-5,8-9H2,(H2,25,29)
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n/an/a 23n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384004
PNG
(CHEMBL2032276)
Show SMILES Cc1cc2oc(nc2cc1O)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C21H22N6O2/c1-12-6-19-17(8-18(12)28)26-21(29-19)16-7-13(9-24-20(16)22)14-10-25-27(11-14)15-2-4-23-5-3-15/h6-11,15,23,28H,2-5H2,1H3,(H2,22,24)
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n/an/a 27n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384008
PNG
(CHEMBL2032296)
Show SMILES CC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c(c1)-c1nc2c(C)c(O)c(C)cc2o1
Show InChI InChI=1S/C24H26N6O3/c1-13-8-20-21(14(2)22(13)32)28-24(33-20)19-9-16(10-26-23(19)25)17-11-27-30(12-17)18-4-6-29(7-5-18)15(3)31/h8-12,18,32H,4-7H2,1-3H3,(H2,25,26)
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n/an/a 28n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384040
PNG
(CHEMBL2032153)
Show SMILES Nc1ncc(cc1-c1nc2ccc(cc2o1)-c1cccnc1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C25H23N7O/c26-24-21(10-18(13-29-24)19-14-30-32(15-19)20-5-8-27-9-6-20)25-31-22-4-3-16(11-23(22)33-25)17-2-1-7-28-12-17/h1-4,7,10-15,20,27H,5-6,8-9H2,(H2,26,29)
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PubMed
n/an/a 28n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384031
PNG
(CHEMBL2032162)
Show SMILES Nc1ncc(cc1-c1nc2ccc(Oc3ccncn3)cc2o1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C24H22N8O2/c25-23-19(9-15(11-28-23)16-12-30-32(13-16)17-3-6-26-7-4-17)24-31-20-2-1-18(10-21(20)34-24)33-22-5-8-27-14-29-22/h1-2,5,8-14,17,26H,3-4,6-7H2,(H2,25,28)
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n/an/a 34n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM50384024
PNG
(CHEMBL2032280 | CHEMBL2079349)
Show SMILES Cc1c(O)ccc2nc(oc12)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C21H22N6O2/c1-12-18(28)3-2-17-19(12)29-21(26-17)16-8-13(9-24-20(16)22)14-10-25-27(11-14)15-4-6-23-7-5-15/h2-3,8-11,15,23,28H,4-7H2,1H3,(H2,22,24)
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n/an/a 34n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50380955
PNG
(CHEMBL2016910)
Show SMILES Clc1ccc2[nH]c(=O)c(cc2c1)-c1nc2CCN(Cc2[nH]1)C(=O)CN1CCOCC1
Show InChI InChI=1S/C21H22ClN5O3/c22-14-1-2-16-13(9-14)10-15(21(29)25-16)20-23-17-3-4-27(11-18(17)24-20)19(28)12-26-5-7-30-8-6-26/h1-2,9-10H,3-8,11-12H2,(H,23,24)(H,25,29)
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n/an/a 35n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM50384022
PNG
(CHEMBL2032282)
Show SMILES Nc1ncc(cc1-c1nc2ccc(O)c(-c3cnccn3)c2o1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C24H22N8O2/c25-23-17(9-14(10-29-23)15-11-30-32(13-15)16-3-5-26-6-4-16)24-31-18-1-2-20(33)21(22(18)34-24)19-12-27-7-8-28-19/h1-2,7-13,16,26,33H,3-6H2,(H2,25,29)
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n/an/a 35n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384043
PNG
(CHEMBL2032150)
Show SMILES Nc1ncc(cc1-c1nc2cc(Cl)cc(F)c2o1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C20H18ClFN6O/c21-13-6-16(22)18-17(7-13)27-20(29-18)15-5-11(8-25-19(15)23)12-9-26-28(10-12)14-1-3-24-4-2-14/h5-10,14,24H,1-4H2,(H2,23,25)
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n/an/a 41n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384014
PNG
(CHEMBL2032290)
Show SMILES Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc1ccc2nc(oc2c1)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C28H28N8O4S/c1-17-2-5-22(6-3-17)41(38,39)35-28(37)33-20-4-7-24-25(13-20)40-27(34-24)23-12-18(14-31-26(23)29)19-15-32-36(16-19)21-8-10-30-11-9-21/h2-7,12-16,21,30H,8-11H2,1H3,(H2,29,31)(H2,33,35,37)
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n/an/a 45n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50380973
PNG
(CHEMBL2016929)
Show SMILES COc1ccc(NC(=O)N2CCc3nc([nH]c3C2)-c2cc3ccccc3[nH]c2=O)cc1
Show InChI InChI=1S/C23H21N5O3/c1-31-16-8-6-15(7-9-16)24-23(30)28-11-10-19-20(13-28)26-21(25-19)17-12-14-4-2-3-5-18(14)27-22(17)29/h2-9,12H,10-11,13H2,1H3,(H,24,30)(H,25,26)(H,27,29)
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n/an/a 46n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 22: 2837-42 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.073
BindingDB Entry DOI: 10.7270/Q2RN38W3
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384021
PNG
(CHEMBL2032283 | CHEMBL2079205)
Show SMILES Nc1ncc(cc1-c1nc2ccc(O)c(-c3ccccc3)c2o1)-c1cnn(c1)C1CCNCC1
Show InChI InChI=1S/C26H24N6O2/c27-25-20(12-17(13-29-25)18-14-30-32(15-18)19-8-10-28-11-9-19)26-31-21-6-7-22(33)23(24(21)34-26)16-4-2-1-3-5-16/h1-7,12-15,19,28,33H,8-11H2,(H2,27,29)
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n/an/a 48n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384009
PNG
(CHEMBL2032295)
Show SMILES CC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c(c1)-c1nc2cc(O)c(C)cc2o1
Show InChI InChI=1S/C23H24N6O3/c1-13-7-21-19(9-20(13)31)27-23(32-21)18-8-15(10-25-22(18)24)16-11-26-29(12-16)17-3-5-28(6-4-17)14(2)30/h7-12,17,31H,3-6H2,1-2H3,(H2,24,25)
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n/an/a 51n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis


Bioorg Med Chem Lett 22: 4044-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.083
BindingDB Entry DOI: 10.7270/Q2FF3TC4
More data for this
Ligand-Target Pair
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