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Compile Data Set for Download or QSAR

Found 174 hits with Last Name = 'guccione' and Initial = 's'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50006952
PNG
(2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Show SMILES COc1ccccc1N1CCN(CCn2c(=O)[nH]c3c4ccccc4[nH]c3c2=O)CC1
Show InChI InChI=1S/C23H25N5O3/c1-31-19-9-5-4-8-18(19)27-13-10-26(11-14-27)12-15-28-22(29)21-20(25-23(28)30)16-6-2-3-7-17(16)24-21/h2-9,24H,10-15H2,1H3,(H,25,30)
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0.210n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity for Alpha-1 adrenergic receptor measured by displacing [3H]-prazosin from rat cortical membranes


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50006953
PNG
(2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Show SMILES COc1ccccc1N1CCN(CCn2c(=O)n(C)c3c4ccccc4n(C)c3c2=O)CC1
Show InChI InChI=1S/C25H29N5O3/c1-26-19-9-5-4-8-18(19)22-23(26)24(31)30(25(32)27(22)2)17-14-28-12-15-29(16-13-28)20-10-6-7-11-21(20)33-3/h4-11H,12-17H2,1-3H3
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0.320n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity for Alpha-1 adrenergic receptor measured by displacing [3H]-prazosin from rat cortical membranes


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50006954
PNG
(2-{2-[4-(2-Chloro-phenyl)-piperazin-1-yl]-ethyl}-4...)
Show SMILES Clc1ccccc1N1CCN(CCn2c(=O)[nH]c3c4ccccc4[nH]c3c2=O)CC1
Show InChI InChI=1S/C22H22ClN5O2/c23-16-6-2-4-8-18(16)27-12-9-26(10-13-27)11-14-28-21(29)20-19(25-22(28)30)15-5-1-3-7-17(15)24-20/h1-8,24H,9-14H2,(H,25,30)
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0.530n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity for Alpha-1 adrenergic receptor measured by displacing [3H]-prazosin from rat cortical membranes


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50006953
PNG
(2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Show SMILES COc1ccccc1N1CCN(CCn2c(=O)n(C)c3c4ccccc4n(C)c3c2=O)CC1
Show InChI InChI=1S/C25H29N5O3/c1-26-19-9-5-4-8-18(19)22-23(26)24(31)30(25(32)27(22)2)17-14-28-12-15-29(16-13-28)20-10-6-7-11-21(20)33-3/h4-11H,12-17H2,1-3H3
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1.5n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity for 5-hydroxytryptamine 1A receptor measured by displacing [3H]-8-OH-DPAT from rat cortical membranes


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50006950
PNG
(2-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-4,9-dihydro-...)
Show SMILES O=c1[nH]c2c3ccccc3[nH]c2c(=O)n1CCN1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C22H23N5O2/c28-21-20-19(17-8-4-5-9-18(17)23-20)24-22(29)27(21)15-12-25-10-13-26(14-11-25)16-6-2-1-3-7-16/h1-9,23H,10-15H2,(H,24,29)
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1.80n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity for Alpha-1 adrenergic receptor measured by displacing [3H]-prazosin from rat cortical membranes


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50118337
PNG
(1-(benzo[b]thiophen-3-yl)-3-(4-(3,4-dihydro-2H-ben...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2OCCCOc12)c1csc2ccccc12
Show InChI InChI=1S/C24H28N2O3S/c27-21(19-17-30-23-8-2-1-5-18(19)23)9-10-25-11-13-26(14-12-25)20-6-3-7-22-24(20)29-16-4-15-28-22/h1-3,5-8,17,21,27H,4,9-16H2
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1.90n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50118332
PNG
(1-(benzo[b]thiophen-3-yl)-3-(4-(quinolin-6-yl)pipe...)
Show SMILES OC(CCN1CCN(CC1)c1ccc2ncccc2c1)c1csc2ccccc12
Show InChI InChI=1S/C24H25N3OS/c28-23(21-17-29-24-6-2-1-5-20(21)24)9-11-26-12-14-27(15-13-26)19-7-8-22-18(16-19)4-3-10-25-22/h1-8,10,16-17,23,28H,9,11-15H2
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2.20n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50118336
PNG
(1-(5-Fluoro-benzo[b]thiophen-3-yl)-3-(4-quinolin-8...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2cccnc12)c1csc2ccc(F)cc12
Show InChI InChI=1S/C24H24FN3OS/c25-18-6-7-23-19(15-18)20(16-30-23)22(29)8-10-27-11-13-28(14-12-27)21-5-1-3-17-4-2-9-26-24(17)21/h1-7,9,15-16,22,29H,8,10-14H2
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2.70n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50118327
PNG
(3-(4-(3,4-dihydro-2H-benzo[b][1,4]dioxepin-6-yl)pi...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2OCCCOc12)c1csc2ccc(F)cc12
Show InChI InChI=1S/C24H27FN2O3S/c25-17-5-6-23-18(15-17)19(16-31-23)21(28)7-8-26-9-11-27(12-10-26)20-3-1-4-22-24(20)30-14-2-13-29-22/h1,3-6,15-16,21,28H,2,7-14H2
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3n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50118338
PNG
(1-(benzo[b]thiophen-3-yl)-3-(4-(benzo[b]thiophen-5...)
Show SMILES OC(CCN1CCN(CC1)c1ccc2sccc2c1)c1csc2ccccc12
Show InChI InChI=1S/C23H24N2OS2/c26-21(20-16-28-23-4-2-1-3-19(20)23)7-9-24-10-12-25(13-11-24)18-5-6-22-17(15-18)8-14-27-22/h1-6,8,14-16,21,26H,7,9-13H2
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3.20n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50118328
PNG
(1-Benzo[b]thiophen-3-yl-3-[4-(1H-indol-4-yl)-piper...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2[nH]ccc12)c1csc2ccccc12
Show InChI InChI=1S/C23H25N3OS/c27-22(19-16-28-23-7-2-1-4-17(19)23)9-11-25-12-14-26(15-13-25)21-6-3-5-20-18(21)8-10-24-20/h1-8,10,16,22,24,27H,9,11-15H2
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4.10n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50118339
PNG
(1-(benzo[b]thiophen-3-yl)-3-(4-(quinolin-3-yl)pipe...)
Show SMILES OC(CCN1CCN(CC1)c1cnc2ccccc2c1)c1csc2ccccc12
Show InChI InChI=1S/C24H25N3OS/c28-23(21-17-29-24-8-4-2-6-20(21)24)9-10-26-11-13-27(14-12-26)19-15-18-5-1-3-7-22(18)25-16-19/h1-8,15-17,23,28H,9-14H2
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4.20n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50118328
PNG
(1-Benzo[b]thiophen-3-yl-3-[4-(1H-indol-4-yl)-piper...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2[nH]ccc12)c1csc2ccccc12
Show InChI InChI=1S/C23H25N3OS/c27-22(19-16-28-23-7-2-1-4-17(19)23)9-11-25-12-14-26(15-13-25)21-6-3-5-20-18(21)8-10-24-20/h1-8,10,16,22,24,27H,9,11-15H2
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5.5n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50118326
PNG
(1-Benzo[b]thiophen-3-yl-3-[4-(2,3-dihydro-benzo[1,...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2OCCOc12)c1csc2ccccc12
Show InChI InChI=1S/C23H26N2O3S/c26-20(18-16-29-22-7-2-1-4-17(18)22)8-9-24-10-12-25(13-11-24)19-5-3-6-21-23(19)28-15-14-27-21/h1-7,16,20,26H,8-15H2
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5.70n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50118330
PNG
(1-(5-Fluoro-benzo[b]thiophen-3-yl)-3-[4-(1H-indol-...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2[nH]ccc12)c1csc2ccc(F)cc12
Show InChI InChI=1S/C23H24FN3OS/c24-16-4-5-23-18(14-16)19(15-29-23)22(28)7-9-26-10-12-27(13-11-26)21-3-1-2-20-17(21)6-8-25-20/h1-6,8,14-15,22,25,28H,7,9-13H2
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5.90n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50118335
PNG
(3-(4-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperazi...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2OCCOc12)c1csc2ccc(F)cc12
Show InChI InChI=1S/C23H25FN2O3S/c24-16-4-5-22-17(14-16)18(15-30-22)20(27)6-7-25-8-10-26(11-9-25)19-2-1-3-21-23(19)29-13-12-28-21/h1-5,14-15,20,27H,6-13H2
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6n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50118324
PNG
(1-(benzo[b]thiophen-3-yl)-3-(4-(quinolin-8-yl)pipe...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2cccnc12)c1csc2ccccc12
Show InChI InChI=1S/C24H25N3OS/c28-22(20-17-29-23-9-2-1-7-19(20)23)10-12-26-13-15-27(16-14-26)21-8-3-5-18-6-4-11-25-24(18)21/h1-9,11,17,22,28H,10,12-16H2
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6.30n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50118329
PNG
(1-Benzo[b]thiophen-3-yl-3-(4-quinolin-2-yl-piperaz...)
Show SMILES OC(CCN1CCN(CC1)c1ccc2ccccc2n1)c1csc2ccccc12
Show InChI InChI=1S/C24H25N3OS/c28-22(20-17-29-23-8-4-2-6-19(20)23)11-12-26-13-15-27(16-14-26)24-10-9-18-5-1-3-7-21(18)25-24/h1-10,17,22,28H,11-16H2
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6.40n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50118330
PNG
(1-(5-Fluoro-benzo[b]thiophen-3-yl)-3-[4-(1H-indol-...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2[nH]ccc12)c1csc2ccc(F)cc12
Show InChI InChI=1S/C23H24FN3OS/c24-16-4-5-23-18(14-16)19(15-29-23)22(28)7-9-26-10-12-27(13-11-26)21-3-1-2-20-17(21)6-8-25-20/h1-6,8,14-15,22,25,28H,7,9-13H2
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7.30n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50118336
PNG
(1-(5-Fluoro-benzo[b]thiophen-3-yl)-3-(4-quinolin-8...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2cccnc12)c1csc2ccc(F)cc12
Show InChI InChI=1S/C24H24FN3OS/c25-18-6-7-23-19(15-18)20(16-30-23)22(29)8-10-27-11-13-28(14-12-27)21-5-1-3-17-4-2-9-26-24(17)21/h1-7,9,15-16,22,29H,8,10-14H2
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7.5n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50118331
PNG
(3-(4-Benzo[1,3]dioxol-4-yl-piperazin-1-yl)-1-(5-fl...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2OCOc12)c1csc2ccc(F)cc12
Show InChI InChI=1S/C22H23FN2O3S/c23-15-4-5-21-16(12-15)17(13-29-21)19(26)6-7-24-8-10-25(11-9-24)18-2-1-3-20-22(18)28-14-27-20/h1-5,12-13,19,26H,6-11,14H2
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9.40n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50118325
PNG
(1-Benzo[b]thiophen-3-yl-3-[4-(1,2-dihydro-quinolin...)
Show SMILES OC(CCN1CCN(CC1)C1Nc2ccccc2C=C1)c1csc2ccccc12
Show InChI InChI=1S/C24H27N3OS/c28-22(20-17-29-23-8-4-2-6-19(20)23)11-12-26-13-15-27(16-14-26)24-10-9-18-5-1-3-7-21(18)25-24/h1-10,17,22,24-25,28H,11-16H2
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9.90n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50118325
PNG
(1-Benzo[b]thiophen-3-yl-3-[4-(1,2-dihydro-quinolin...)
Show SMILES OC(CCN1CCN(CC1)C1Nc2ccccc2C=C1)c1csc2ccccc12
Show InChI InChI=1S/C24H27N3OS/c28-22(20-17-29-23-8-4-2-6-19(20)23)11-12-26-13-15-27(16-14-26)24-10-9-18-5-1-3-7-21(18)25-24/h1-10,17,22,24-25,28H,11-16H2
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10.2n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50006958
PNG
(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...)
Show SMILES COc1ccccc1N1CCN(CCCn2c(=O)[nH]c3c4ccccc4[nH]c3c2=O)CC1
Show InChI InChI=1S/C24H27N5O3/c1-32-20-10-5-4-9-19(20)28-15-13-27(14-16-28)11-6-12-29-23(30)22-21(26-24(29)31)17-7-2-3-8-18(17)25-22/h2-5,7-10,25H,6,11-16H2,1H3,(H,26,31)
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13n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity for Alpha-1 adrenergic receptor measured by displacing [3H]-prazosin from rat cortical membranes


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50118335
PNG
(3-(4-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperazi...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2OCCOc12)c1csc2ccc(F)cc12
Show InChI InChI=1S/C23H25FN2O3S/c24-16-4-5-22-17(14-16)18(15-30-22)20(27)6-7-25-8-10-26(11-9-25)19-2-1-3-21-23(19)29-13-12-28-21/h1-5,14-15,20,27H,6-13H2
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16n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50118333
PNG
(1-Benzo[b]thiophen-3-yl-3-(4-quinolin-4-yl-piperaz...)
Show SMILES OC(CCN1CCN(CC1)c1ccnc2ccccc12)c1csc2ccccc12
Show InChI InChI=1S/C24H25N3OS/c28-23(20-17-29-24-8-4-2-5-18(20)24)10-12-26-13-15-27(16-14-26)22-9-11-25-21-7-3-1-6-19(21)22/h1-9,11,17,23,28H,10,12-16H2
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19.4n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50118327
PNG
(3-(4-(3,4-dihydro-2H-benzo[b][1,4]dioxepin-6-yl)pi...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2OCCCOc12)c1csc2ccc(F)cc12
Show InChI InChI=1S/C24H27FN2O3S/c25-17-5-6-23-18(15-17)19(16-31-23)21(28)7-8-26-9-11-27(12-10-26)20-3-1-4-22-24(20)30-14-2-13-29-22/h1,3-6,15-16,21,28H,2,7-14H2
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21.2n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50118324
PNG
(1-(benzo[b]thiophen-3-yl)-3-(4-(quinolin-8-yl)pipe...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2cccnc12)c1csc2ccccc12
Show InChI InChI=1S/C24H25N3OS/c28-22(20-17-29-23-9-2-1-7-19(20)23)10-12-26-13-15-27(16-14-26)21-8-3-5-18-6-4-11-25-24(18)21/h1-9,11,17,22,28H,10,12-16H2
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24n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50118340
PNG
(1-(benzo[b]thiophen-3-yl)-3-(4-(quinolin-5-yl)pipe...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2ncccc12)c1csc2ccccc12
Show InChI InChI=1S/C24H25N3OS/c28-23(20-17-29-24-9-2-1-5-18(20)24)10-12-26-13-15-27(16-14-26)22-8-3-7-21-19(22)6-4-11-25-21/h1-9,11,17,23,28H,10,12-16H2
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32.5n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50118340
PNG
(1-(benzo[b]thiophen-3-yl)-3-(4-(quinolin-5-yl)pipe...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2ncccc12)c1csc2ccccc12
Show InChI InChI=1S/C24H25N3OS/c28-23(20-17-29-24-9-2-1-5-18(20)24)10-12-26-13-15-27(16-14-26)22-8-3-7-21-19(22)6-4-11-25-21/h1-9,11,17,23,28H,10,12-16H2
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36.8n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50118326
PNG
(1-Benzo[b]thiophen-3-yl-3-[4-(2,3-dihydro-benzo[1,...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2OCCOc12)c1csc2ccccc12
Show InChI InChI=1S/C23H26N2O3S/c26-20(18-16-29-22-7-2-1-4-17(18)22)8-9-24-10-12-25(13-11-24)19-5-3-6-21-23(19)28-15-14-27-21/h1-7,16,20,26H,8-15H2
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50n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50006952
PNG
(2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Show SMILES COc1ccccc1N1CCN(CCn2c(=O)[nH]c3c4ccccc4[nH]c3c2=O)CC1
Show InChI InChI=1S/C23H25N5O3/c1-31-19-9-5-4-8-18(19)27-13-10-26(11-14-27)12-15-28-22(29)21-20(25-23(28)30)16-6-2-3-7-17(16)24-21/h2-9,24H,10-15H2,1H3,(H,25,30)
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50n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity for 5-hydroxytryptamine 1A receptor measured by displacing [3H]-8-OH-DPAT from rat cortical membranes


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50118331
PNG
(3-(4-Benzo[1,3]dioxol-4-yl-piperazin-1-yl)-1-(5-fl...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2OCOc12)c1csc2ccc(F)cc12
Show InChI InChI=1S/C22H23FN2O3S/c23-15-4-5-21-16(12-15)17(13-29-21)19(26)6-7-24-8-10-25(11-9-24)18-2-1-3-20-22(18)28-14-27-20/h1-5,12-13,19,26H,6-11,14H2
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58n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50118341
PNG
(1-(5-Fluoro-benzo[b]thiophen-3-yl)-3-(4-naphthalen...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2ccccc12)c1csc2ccc(F)cc12
Show InChI InChI=1S/C25H25FN2OS/c26-19-8-9-25-21(16-19)22(17-30-25)24(29)10-11-27-12-14-28(15-13-27)23-7-3-5-18-4-1-2-6-20(18)23/h1-9,16-17,24,29H,10-15H2
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62n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50118342
PNG
(1-(benzo[b]thiophen-3-yl)-3-(4-(naphthalen-1-yl)pi...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2ccccc12)c1csc2ccccc12
Show InChI InChI=1S/C25H26N2OS/c28-24(22-18-29-25-11-4-3-9-21(22)25)12-13-26-14-16-27(17-15-26)23-10-5-7-19-6-1-2-8-20(19)23/h1-11,18,24,28H,12-17H2
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66.7n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50118337
PNG
(1-(benzo[b]thiophen-3-yl)-3-(4-(3,4-dihydro-2H-ben...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2OCCCOc12)c1csc2ccccc12
Show InChI InChI=1S/C24H28N2O3S/c27-21(19-17-30-23-8-2-1-5-18(19)23)9-10-25-11-13-26(14-12-25)20-6-3-7-22-24(20)29-16-4-15-28-22/h1-3,5-8,17,21,27H,4,9-16H2
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77n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50118342
PNG
(1-(benzo[b]thiophen-3-yl)-3-(4-(naphthalen-1-yl)pi...)
Show SMILES OC(CCN1CCN(CC1)c1cccc2ccccc12)c1csc2ccccc12
Show InChI InChI=1S/C25H26N2OS/c28-24(22-18-29-25-11-4-3-9-21(22)25)12-13-26-14-16-27(17-15-26)23-10-5-7-19-6-1-2-8-20(19)23/h1-11,18,24,28H,12-17H2
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81.7n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50001901
PNG
(1-(2-Chloro-phenyl)-piperazine | CHEMBL9841)
Show SMILES Clc1ccccc1N1CCNCC1
Show InChI InChI=1S/C10H13ClN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2
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226n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity for 5-HT1A measured by displacing [3H]-8-OH-DPAT from rat cortical membranes; Not determined


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50001862
PNG
((N-(o-methoxyphenyl)piperazine)1-(2-Methoxy-phenyl...)
Show SMILES COc1ccccc1N1CCNCC1
Show InChI InChI=1S/C11H16N2O/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3
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281n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity for 5-hydroxytryptamine 1A receptor measured by displacing [3H]-8-OH-DPAT from rat cortical membranes


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50118333
PNG
(1-Benzo[b]thiophen-3-yl-3-(4-quinolin-4-yl-piperaz...)
Show SMILES OC(CCN1CCN(CC1)c1ccnc2ccccc12)c1csc2ccccc12
Show InChI InChI=1S/C24H25N3OS/c28-23(20-17-29-24-8-4-2-5-18(20)24)10-12-26-13-15-27(16-14-26)22-9-11-25-21-7-3-1-6-19(21)22/h1-9,11,17,23,28H,10,12-16H2
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301n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50006958
PNG
(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...)
Show SMILES COc1ccccc1N1CCN(CCCn2c(=O)[nH]c3c4ccccc4[nH]c3c2=O)CC1
Show InChI InChI=1S/C24H27N5O3/c1-32-20-10-5-4-9-19(20)28-15-13-27(14-16-28)11-6-12-29-23(30)22-21(26-24(29)31)17-7-2-3-8-18(17)25-22/h2-5,7-10,25H,6,11-16H2,1H3,(H,26,31)
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308n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity for 5-hydroxytryptamine 1A receptor measured by displacing [3H]-8-OH-DPAT from rat cortical membranes


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50118329
PNG
(1-Benzo[b]thiophen-3-yl-3-(4-quinolin-2-yl-piperaz...)
Show SMILES OC(CCN1CCN(CC1)c1ccc2ccccc2n1)c1csc2ccccc12
Show InChI InChI=1S/C24H25N3OS/c28-22(20-17-29-23-8-4-2-6-19(20)23)11-12-26-13-15-27(16-14-26)24-10-9-18-5-1-3-7-21(18)25-24/h1-10,17,22,28H,11-16H2
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377n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50118332
PNG
(1-(benzo[b]thiophen-3-yl)-3-(4-(quinolin-6-yl)pipe...)
Show SMILES OC(CCN1CCN(CC1)c1ccc2ncccc2c1)c1csc2ccccc12
Show InChI InChI=1S/C24H25N3OS/c28-23(21-17-29-24-6-2-1-5-20(21)24)9-11-26-12-14-27(15-13-26)19-7-8-22-18(16-19)4-3-10-25-22/h1-8,10,16-17,23,28H,9,11-15H2
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546n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50001901
PNG
(1-(2-Chloro-phenyl)-piperazine | CHEMBL9841)
Show SMILES Clc1ccccc1N1CCNCC1
Show InChI InChI=1S/C10H13ClN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2
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710n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity measured for alpha-1 adrenergic receptor by displacement of [3H]-prazosin from rat cortical membranes


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50118338
PNG
(1-(benzo[b]thiophen-3-yl)-3-(4-(benzo[b]thiophen-5...)
Show SMILES OC(CCN1CCN(CC1)c1ccc2sccc2c1)c1csc2ccccc12
Show InChI InChI=1S/C23H24N2OS2/c26-21(20-16-28-23-4-2-1-3-19(20)23)7-9-24-10-12-25(13-11-24)18-5-6-22-17(15-18)8-14-27-22/h1-6,8,14-16,21,26H,7,9-13H2
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913n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50118339
PNG
(1-(benzo[b]thiophen-3-yl)-3-(4-(quinolin-3-yl)pipe...)
Show SMILES OC(CCN1CCN(CC1)c1cnc2ccccc2c1)c1csc2ccccc12
Show InChI InChI=1S/C24H25N3OS/c28-23(21-17-29-24-8-4-2-6-20(21)24)9-10-26-11-13-27(14-12-26)19-15-18-5-1-3-7-22(18)25-16-19/h1-8,15-17,23,28H,9-14H2
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995n/an/an/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenates


J Med Chem 45: 4128-39 (2002)


Article DOI: 10.1021/jm0111200
BindingDB Entry DOI: 10.7270/Q2X63M87
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor and beta-3 adrenergic receptor


(Homo sapiens (Human))
BDBM50006958
PNG
(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...)
Show SMILES COc1ccccc1N1CCN(CCCn2c(=O)[nH]c3c4ccccc4[nH]c3c2=O)CC1
Show InChI InChI=1S/C24H27N5O3/c1-32-20-10-5-4-9-19(20)28-15-13-27(14-16-28)11-6-12-29-23(30)22-21(26-24(29)31)17-7-2-3-8-18(17)25-22/h2-5,7-10,25H,6,11-16H2,1H3,(H,26,31)
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1.18E+3n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity towards Beta-2 adrenergic receptor in human periipheral mononuclear leukocyte membranes using [125I]-pindolol


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50001862
PNG
((N-(o-methoxyphenyl)piperazine)1-(2-Methoxy-phenyl...)
Show SMILES COc1ccccc1N1CCNCC1
Show InChI InChI=1S/C11H16N2O/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3
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3.51E+3n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity measured for alpha-1 adrenergic receptor by displacement of [3H]-prazosin from rat cortical membranes


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50006955
PNG
(2-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Show SMILES COc1ccc(cc1)N1CCN(CCn2c(=O)[nH]c3c4ccccc4[nH]c3c2=O)CC1
Show InChI InChI=1S/C23H25N5O3/c1-31-17-8-6-16(7-9-17)27-13-10-26(11-14-27)12-15-28-22(29)21-20(25-23(28)30)18-4-2-3-5-19(18)24-21/h2-9,24H,10-15H2,1H3,(H,25,30)
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>5.00E+3n/an/an/an/an/an/an/an/a



Universitá di Catania

Curated by ChEMBL


Assay Description
Binding affinity for Alpha-1 adrenergic receptor measured by displacing [3H]-prazosin from rat cortical membranes


J Med Chem 34: 1850-4 (1991)


Article DOI: 10.1021/jm00110a014
BindingDB Entry DOI: 10.7270/Q25B01FV
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50283470
PNG
(2-(4-Chloro-phenylamino)-5H-[1,3]thiazino[5,4-b]in...)
Show SMILES Oc1sc(Nc2ccc(Cl)cc2)nc2c1nc1ccccc21
Show InChI InChI=1S/C16H10ClN3OS/c17-9-5-7-10(8-6-9)18-16-20-13-11-3-1-2-4-12(11)19-14(13)15(21)22-16/h1-8,21H,(H,18,20)
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2.90E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of human leukocyte Elastase at 23 microM concentration from human polymorphonuclear leukocytes


Bioorg Med Chem Lett 4: 2399-2404 (1994)


Article DOI: 10.1016/S0960-894X(01)80398-X
BindingDB Entry DOI: 10.7270/Q2BZ65Z8
More data for this
Ligand-Target Pair
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