Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Eukaryotic initiation factor 4A-III (Homo sapiens (Human)) | BDBM50235737![]() (CHEMBL4070102) | PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description ATP competitive inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 expressed in Escherichia coli BL21(DE3) ... | Bioorg Med Chem 25: 2200-2209 (2017) Article DOI: 10.1016/j.bmc.2017.02.035 BindingDB Entry DOI: 10.7270/Q2902613 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50081472![]() ((2S,3S)-4-(6-Amino-purin-9-yl)-2,3-dihydroxy-butyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Inhibition of human SAHH | Bioorg Med Chem 16: 6575-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.020 BindingDB Entry DOI: 10.7270/Q2SN08SX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50244094![]() (9-[(10R,20S,30S,40R)-30,40-Epoxy-20-hydroxy-cyclop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Inhibition of human SAHH | Bioorg Med Chem 16: 6575-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.020 BindingDB Entry DOI: 10.7270/Q2SN08SX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50244095![]() (9-[(10R,20S,30R,50R)-30,40-Epoxy-20-hydroxy-cyclop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.03E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gifu University Curated by ChEMBL | Assay Description Inhibition of human SAHH | Bioorg Med Chem 16: 6575-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.020 BindingDB Entry DOI: 10.7270/Q2SN08SX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50243934![]() (2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2,3,6-triflu...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BCoR-BCL6 (Homo sapiens) | BDBM50260529![]() (CHEMBL4077626) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of C-terminal biotin-labelled BCoR (Arg498 to 514Pro residues) binding to recombinant FLAG-tagged BCL6 BTB (5 to 129 residues) (unknown or... | Bioorg Med Chem 25: 4876-4886 (2017) Article DOI: 10.1016/j.bmc.2017.07.037 BindingDB Entry DOI: 10.7270/Q2G44SR7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50244291![]() (4-[(2-Fluorobenzyl)amino]-2-[(4-morpholin-4-ylphen...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50243884![]() (4-[(2,5-Difluorobenzyl)amino]-2-[(4-morpholin-4-yl...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50244292![]() (4-[(3-Fluorobenzyl)amino]-2-[(4-morpholin-4-ylphen...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50243933![]() (2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2,3,5-triflu...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50243882![]() (4-[(2,3-Difluorobenzyl)amino]-2-[(4-morpholin-4-yl...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50243885![]() (4-[(2,6-Difluorobenzyl)amino]-2-[(4-morpholin-4-yl...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50243932![]() (4-[(3,5-Difluorobenzyl)amino]-2-[(4-morpholin-4-yl...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XI (Homo sapiens (Human)) | BDBM339899![]() ((3S)-1-[(trans-4-{(1S)-1-[(tert-Butoxycarbonyl)ami...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Co., Ltd US Patent | Assay Description 0.35 μg/mL human FXIa was allowed to react with a substrate and a test compound in a 30 mmol/L HEPES buffer solution (pH 7.4) that contained 145... | US Patent US9758480 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50244256![]() (4-Benzylamino-2-{[4-(4-methylpiperazin-1-yl)phenyl...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50244258![]() (4-(benzylamino)-2-(4-morpholinophenylamino)pyrimid...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XI (Homo sapiens (Human)) | BDBM339903![]() (US9758480, 114) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Co., Ltd US Patent | Assay Description 0.35 μg/mL human FXIa was allowed to react with a substrate and a test compound in a 30 mmol/L HEPES buffer solution (pH 7.4) that contained 145... | US Patent US9758480 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50244257![]() (4-Benzylamino-2-[(4-piperazin-1-ylphenyl)amino]-py...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50244331![]() (4-[(2-Chlorobenzyl)amino]-2-[(4-morpholin-4-ylphen...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XI (Homo sapiens (Human)) | BDBM339926![]() (Pentyl 5-{[(3S)-1-[(trans-4-{(1S)-1-[(tert-butoxyc...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Co., Ltd US Patent | Assay Description 0.35 μg/mL human FXIa was allowed to react with a substrate and a test compound in a 30 mmol/L HEPES buffer solution (pH 7.4) that contained 145... | US Patent US9758480 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50244329![]() (4-[(2-Methoxybenzyl)amino]-2-[(4-morpholin-4-ylphe...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XI (Homo sapiens (Human)) | BDBM339882![]() (5-{(2S,3S)-1-[trans-4-(tert-Butoxycarbonylaminomet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Co., Ltd US Patent | Assay Description 0.35 μg/mL human FXIa was allowed to react with a substrate and a test compound in a 30 mmol/L HEPES buffer solution (pH 7.4) that contained 145... | US Patent US9758480 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XI (Homo sapiens (Human)) | BDBM339927![]() (Cyclopropylmethyl 5-{[(3S)-1-[(trans-4-{(1S)-1-[(t...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Co., Ltd US Patent | Assay Description 0.35 μg/mL human FXIa was allowed to react with a substrate and a test compound in a 30 mmol/L HEPES buffer solution (pH 7.4) that contained 145... | US Patent US9758480 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50244294![]() (4-[(2-Methylbenzyl)amino]-2-[(4-morpholin-4-ylphen...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
U5 small nuclear ribonucleoprotein 200 kDa helicase (Homo sapiens (Human)) | BDBM50260424![]() (CHEMBL4091579) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin... | Bioorg Med Chem 25: 4753-4767 (2017) Article DOI: 10.1016/j.bmc.2017.07.017 BindingDB Entry DOI: 10.7270/Q27M0BDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XI (Homo sapiens (Human)) | BDBM339889![]() (US9758480, 35) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Co., Ltd US Patent | Assay Description 0.35 μg/mL human FXIa was allowed to react with a substrate and a test compound in a 30 mmol/L HEPES buffer solution (pH 7.4) that contained 145... | US Patent US9758480 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50244223![]() (4-Benzylamino-2-{[4-(4-hydroxypiperidin-1-yl)pheny...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50244259![]() (4-Benzylamino-2-{[4-(1-methylpiperidin-4-yl)phenyl...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50243794![]() (4-[(3-Hydroxybenzyl)amino]-2-[(4-morpholin-4-ylphe...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50197554![]() (2-(3-chloro-4-hydroxyphenethylamino)-4-(benzylamin...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
U5 small nuclear ribonucleoprotein 200 kDa helicase (Homo sapiens (Human)) | BDBM50260390![]() (CHEMBL4070683) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin... | Bioorg Med Chem 25: 4753-4767 (2017) Article DOI: 10.1016/j.bmc.2017.07.017 BindingDB Entry DOI: 10.7270/Q27M0BDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50244330![]() (4-[(2-Hydroxybenzyl)amino]-2-[(4-morpholin-4-ylphe...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50244369![]() (4-{[2-(Methylsulfanyl)benzyl]amino}-2-[(4-morpholi...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
U5 small nuclear ribonucleoprotein 200 kDa helicase (Homo sapiens (Human)) | BDBM50260424![]() (CHEMBL4091579) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of full length recombinant human N-terminal His-tagged BRR2 helicase activity expressed in baculovirus infected Sf9 cells using 5'-[FITC]-... | Bioorg Med Chem 25: 4753-4767 (2017) Article DOI: 10.1016/j.bmc.2017.07.017 BindingDB Entry DOI: 10.7270/Q27M0BDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50244332![]() (2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2-trifluorom...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50243725![]() (4-[(3-Methoxybenzyl)amino]-2-[(4-morpholin-4-ylphe...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XI (Homo sapiens (Human)) | BDBM339888![]() (US9758480, 34) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Co., Ltd US Patent | Assay Description 0.35 μg/mL human FXIa was allowed to react with a substrate and a test compound in a 30 mmol/L HEPES buffer solution (pH 7.4) that contained 145... | US Patent US9758480 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XI (Homo sapiens (Human)) | BDBM339925![]() (Tetrahydro-2H-pyran-4-ylmethyl 5-{[(3S)-1-[(trans-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Co., Ltd US Patent | Assay Description 0.35 μg/mL human FXIa was allowed to react with a substrate and a test compound in a 30 mmol/L HEPES buffer solution (pH 7.4) that contained 145... | US Patent US9758480 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XI (Homo sapiens (Human)) | BDBM339920![]() (US9758480, 184 | tert-Butyl [(1S)-1-(trans-4-{[(2S...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Co., Ltd US Patent | Assay Description 0.35 μg/mL human FXIa was allowed to react with a substrate and a test compound in a 30 mmol/L HEPES buffer solution (pH 7.4) that contained 145... | US Patent US9758480 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XI (Homo sapiens (Human)) | BDBM339890![]() (US9758480, 38) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Co., Ltd US Patent | Assay Description 0.35 μg/mL human FXIa was allowed to react with a substrate and a test compound in a 30 mmol/L HEPES buffer solution (pH 7.4) that contained 145... | US Patent US9758480 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XI (Homo sapiens (Human)) | BDBM339919![]() (Cyclopentylmethyl 5-{[(3S)-1-[(trans-4-{(1S)-1-[(t...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Co., Ltd US Patent | Assay Description 0.35 μg/mL human FXIa was allowed to react with a substrate and a test compound in a 30 mmol/L HEPES buffer solution (pH 7.4) that contained 145... | US Patent US9758480 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XI (Homo sapiens (Human)) | BDBM339884![]() (5-{(2S,3S)-1-[trans-4-(tert-Butoxycarbonylaminomet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Co., Ltd US Patent | Assay Description 0.35 μg/mL human FXIa was allowed to react with a substrate and a test compound in a 30 mmol/L HEPES buffer solution (pH 7.4) that contained 145... | US Patent US9758480 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XI (Homo sapiens (Human)) | BDBM339896![]() (5-[(2S,3S)-1-{trans-4-[(1S)-1-(tert-Butoxycarbonyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Co., Ltd US Patent | Assay Description 0.35 μg/mL human FXIa was allowed to react with a substrate and a test compound in a 30 mmol/L HEPES buffer solution (pH 7.4) that contained 145... | US Patent US9758480 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50243723![]() (4-[(3-Chlorobenzyl)amino]-2-[(4-morpholin-4-ylphen...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Signal transducer and activator of transcription 6 (Homo sapiens (Human)) | BDBM50244366![]() (2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2-nitrobenzy...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc Curated by ChEMBL | Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells | Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
U5 small nuclear ribonucleoprotein 200 kDa helicase (Homo sapiens (Human)) | BDBM50260390![]() (CHEMBL4070683) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin... | Bioorg Med Chem 25: 4753-4767 (2017) Article DOI: 10.1016/j.bmc.2017.07.017 BindingDB Entry DOI: 10.7270/Q27M0BDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XI (Homo sapiens (Human)) | BDBM339906![]() ((2S)-Tetrahydrofuran-2-ylmethyl 5-({(3S)-1-[(trans...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Co., Ltd US Patent | Assay Description 0.35 μg/mL human FXIa was allowed to react with a substrate and a test compound in a 30 mmol/L HEPES buffer solution (pH 7.4) that contained 145... | US Patent US9758480 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
U5 small nuclear ribonucleoprotein 200 kDa helicase (Homo sapiens (Human)) | BDBM50260423![]() (CHEMBL4104317) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin... | Bioorg Med Chem 25: 4753-4767 (2017) Article DOI: 10.1016/j.bmc.2017.07.017 BindingDB Entry DOI: 10.7270/Q27M0BDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XI (Homo sapiens (Human)) | BDBM339893![]() (5-[(2S,3S)-1-{trans-4-[1-(tert-Butoxycarbonyl)amin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Co., Ltd US Patent | Assay Description 0.35 μg/mL human FXIa was allowed to react with a substrate and a test compound in a 30 mmol/L HEPES buffer solution (pH 7.4) that contained 145... | US Patent US9758480 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic initiation factor 4A-III (Homo sapiens (Human)) | BDBM50283464![]() (CHEMBL4162764) | PDB MMDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar | PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c... | ACS Med Chem Lett 8: 1077-1082 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7KT3 | |||||||||||
More data for this Ligand-Target Pair |
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