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Compile Data Set for Download or QSAR

Found 420 hits with Last Name = 'jeanty' and Initial = 'm'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melatonin receptor


(Homo sapiens (Human))
BDBM50340329
PNG
(4-azamelatonin | CHEMBL1760944)
Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2n1
Show InChI InChI=1S/C12H15N3O2/c1-8(16)13-6-5-9-7-14-10-3-4-11(17-2)15-12(9)10/h3-4,7,14H,5-6H2,1-2H3,(H,13,16)
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0.200n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM9019
PNG
(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1
Show InChI InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)
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0.25n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340324
PNG
(CHEMBL1760946 | N-(2-(6-Methoxy-1H-pyrrolo[2,3-b]p...)
Show SMILES CCC(=O)NCCn1ccc2ccc(OC)nc12
Show InChI InChI=1S/C13H17N3O2/c1-3-11(17)14-7-9-16-8-6-10-4-5-12(18-2)15-13(10)16/h4-6,8H,3,7,9H2,1-2H3,(H,14,17)
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0.280n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340329
PNG
(4-azamelatonin | CHEMBL1760944)
Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2n1
Show InChI InChI=1S/C12H15N3O2/c1-8(16)13-6-5-9-7-14-10-3-4-11(17-2)15-12(9)10/h3-4,7,14H,5-6H2,1-2H3,(H,13,16)
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0.300n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340338
PNG
(CHEMBL1760947 | N-(2-(6-Methoxy-1H-pyrrolo[2,3-b]p...)
Show SMILES CCCC(=O)NCCn1ccc2ccc(OC)nc12
Show InChI InChI=1S/C14H19N3O2/c1-3-4-12(18)15-8-10-17-9-7-11-5-6-13(19-2)16-14(11)17/h5-7,9H,3-4,8,10H2,1-2H3,(H,15,18)
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0.300n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM9019
PNG
(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1
Show InChI InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)
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0.340n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340325
PNG
(CHEMBL1760945 | N-(2-(6-Methoxy-1H-pyrrolo[2,3-b]p...)
Show SMILES COc1ccc2ccn(CCNC(C)=O)c2n1
Show InChI InChI=1S/C12H15N3O2/c1-9(16)13-6-8-15-7-5-10-3-4-11(17-2)14-12(10)15/h3-5,7H,6,8H2,1-2H3,(H,13,16)
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0.600n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340327
PNG
(CHEMBL1760957 | N-(2-(5,6,7,8-Tetrahydro-2-methoxy...)
Show SMILES COc1ccc2c3CCCCc3n(CCNC(C)=O)c2n1
Show InChI InChI=1S/C16H21N3O2/c1-11(20)17-9-10-19-14-6-4-3-5-12(14)13-7-8-15(21-2)18-16(13)19/h7-8H,3-6,9-10H2,1-2H3,(H,17,20)
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0.680n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340338
PNG
(CHEMBL1760947 | N-(2-(6-Methoxy-1H-pyrrolo[2,3-b]p...)
Show SMILES CCCC(=O)NCCn1ccc2ccc(OC)nc12
Show InChI InChI=1S/C14H19N3O2/c1-3-4-12(18)15-8-10-17-9-7-11-5-6-13(19-2)16-14(11)17/h5-7,9H,3-4,8,10H2,1-2H3,(H,15,18)
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1.30n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340325
PNG
(CHEMBL1760945 | N-(2-(6-Methoxy-1H-pyrrolo[2,3-b]p...)
Show SMILES COc1ccc2ccn(CCNC(C)=O)c2n1
Show InChI InChI=1S/C12H15N3O2/c1-9(16)13-6-8-15-7-5-10-3-4-11(17-2)14-12(10)15/h3-5,7H,6,8H2,1-2H3,(H,13,16)
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1.40n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340324
PNG
(CHEMBL1760946 | N-(2-(6-Methoxy-1H-pyrrolo[2,3-b]p...)
Show SMILES CCC(=O)NCCn1ccc2ccc(OC)nc12
Show InChI InChI=1S/C13H17N3O2/c1-3-11(17)14-7-9-16-8-6-10-4-5-12(18-2)15-13(10)16/h4-6,8H,3,7,9H2,1-2H3,(H,14,17)
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3.30n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340326
PNG
(CHEMBL1760956 | N-(2-(3-iodo-6-methoxy-1H-pyrrolo[...)
Show SMILES COc1ccc2c(I)cn(CCNC(C)=O)c2n1
Show InChI InChI=1S/C12H14IN3O2/c1-8(17)14-5-6-16-7-10(13)9-3-4-11(18-2)15-12(9)16/h3-4,7H,5-6H2,1-2H3,(H,14,17)
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5n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340327
PNG
(CHEMBL1760957 | N-(2-(5,6,7,8-Tetrahydro-2-methoxy...)
Show SMILES COc1ccc2c3CCCCc3n(CCNC(C)=O)c2n1
Show InChI InChI=1S/C16H21N3O2/c1-11(20)17-9-10-19-14-6-4-3-5-12(14)13-7-8-15(21-2)18-16(13)19/h7-8H,3-6,9-10H2,1-2H3,(H,17,20)
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9n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340326
PNG
(CHEMBL1760956 | N-(2-(3-iodo-6-methoxy-1H-pyrrolo[...)
Show SMILES COc1ccc2c(I)cn(CCNC(C)=O)c2n1
Show InChI InChI=1S/C12H14IN3O2/c1-8(17)14-5-6-16-7-10(13)9-3-4-11(18-2)15-12(9)16/h3-4,7H,5-6H2,1-2H3,(H,14,17)
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16n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340328
PNG
(CHEMBL1760955 | N-(2-(6-methoxy-3-(2,2,2-trifluoro...)
Show SMILES COc1ccc2c(cn(CCNC(C)=O)c2n1)C(=O)C(F)(F)F
Show InChI InChI=1S/C14H14F3N3O3/c1-8(21)18-5-6-20-7-10(12(22)14(15,16)17)9-3-4-11(23-2)19-13(9)20/h3-4,7H,5-6H2,1-2H3,(H,18,21)
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30n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340330
PNG
(7-azamelatonin | CHEMBL137969 | N-[2-(5-Methoxy-1H...)
Show SMILES COc1cnc2[nH]cc(CCNC(C)=O)c2c1
Show InChI InChI=1S/C12H15N3O2/c1-8(16)13-4-3-9-6-14-12-11(9)5-10(17-2)7-15-12/h5-7H,3-4H2,1-2H3,(H,13,16)(H,14,15)
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40n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340328
PNG
(CHEMBL1760955 | N-(2-(6-methoxy-3-(2,2,2-trifluoro...)
Show SMILES COc1ccc2c(cn(CCNC(C)=O)c2n1)C(=O)C(F)(F)F
Show InChI InChI=1S/C14H14F3N3O3/c1-8(21)18-5-6-20-7-10(12(22)14(15,16)17)9-3-4-11(23-2)19-13(9)20/h3-4,7H,5-6H2,1-2H3,(H,18,21)
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91n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340330
PNG
(7-azamelatonin | CHEMBL137969 | N-[2-(5-Methoxy-1H...)
Show SMILES COc1cnc2[nH]cc(CCNC(C)=O)c2c1
Show InChI InChI=1S/C12H15N3O2/c1-8(16)13-4-3-9-6-14-12-11(9)5-10(17-2)7-15-12/h5-7H,3-4H2,1-2H3,(H,13,16)(H,14,15)
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117n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340331
PNG
(CHEMBL1760950 | N-(2-(6-methoxy-3-(piperidin-1-ylm...)
Show SMILES COc1ccc2c(CN3CCCCC3)cn(CCNC(C)=O)c2n1
Show InChI InChI=1S/C18H26N4O2/c1-14(23)19-8-11-22-13-15(12-21-9-4-3-5-10-21)16-6-7-17(24-2)20-18(16)22/h6-7,13H,3-5,8-12H2,1-2H3,(H,19,23)
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510n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340332
PNG
(CHEMBL1760951 | N-(2-(6-methoxy-3-(morpholinomethy...)
Show SMILES COc1ccc2c(CN3CCOCC3)cn(CCNC(C)=O)c2n1
Show InChI InChI=1S/C17H24N4O3/c1-13(22)18-5-6-21-12-14(11-20-7-9-24-10-8-20)15-3-4-16(23-2)19-17(15)21/h3-4,12H,5-11H2,1-2H3,(H,18,22)
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550n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340331
PNG
(CHEMBL1760950 | N-(2-(6-methoxy-3-(piperidin-1-ylm...)
Show SMILES COc1ccc2c(CN3CCCCC3)cn(CCNC(C)=O)c2n1
Show InChI InChI=1S/C18H26N4O2/c1-14(23)19-8-11-22-13-15(12-21-9-4-3-5-10-21)16-6-7-17(24-2)20-18(16)22/h6-7,13H,3-5,8-12H2,1-2H3,(H,19,23)
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742n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340333
PNG
(CHEMBL1760952 | N-(2-(3-((4-(3-chlorophenyl)pipera...)
Show SMILES COc1ccc2c(CN3CCN(CC3)c3cccc(Cl)c3)cn(CCNC(C)=O)c2n1
Show InChI InChI=1S/C23H28ClN5O2/c1-17(30)25-8-9-29-16-18(21-6-7-22(31-2)26-23(21)29)15-27-10-12-28(13-11-27)20-5-3-4-19(24)14-20/h3-7,14,16H,8-13,15H2,1-2H3,(H,25,30)
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929n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340334
PNG
(CHEMBL1760954 | N-(2-(6-methoxy-3-((methylamino)me...)
Show SMILES CNCc1cn(CCNC(C)=O)c2nc(OC)ccc12
Show InChI InChI=1S/C14H20N4O2/c1-10(19)16-6-7-18-9-11(8-15-2)12-4-5-13(20-3)17-14(12)18/h4-5,9,15H,6-8H2,1-3H3,(H,16,19)
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1.09E+3n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340333
PNG
(CHEMBL1760952 | N-(2-(3-((4-(3-chlorophenyl)pipera...)
Show SMILES COc1ccc2c(CN3CCN(CC3)c3cccc(Cl)c3)cn(CCNC(C)=O)c2n1
Show InChI InChI=1S/C23H28ClN5O2/c1-17(30)25-8-9-29-16-18(21-6-7-22(31-2)26-23(21)29)15-27-10-12-28(13-11-27)20-5-3-4-19(24)14-20/h3-7,14,16H,8-13,15H2,1-2H3,(H,25,30)
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1.21E+3n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340335
PNG
(CHEMBL1760949 | N-(2-(3-((benzyl(methyl)amino)meth...)
Show SMILES COc1ccc2c(CN(C)Cc3ccccc3)cn(CCNC(C)=O)c2n1
Show InChI InChI=1S/C21H26N4O2/c1-16(26)22-11-12-25-15-18(19-9-10-20(27-3)23-21(19)25)14-24(2)13-17-7-5-4-6-8-17/h4-10,15H,11-14H2,1-3H3,(H,22,26)
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4.01E+3n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340336
PNG
(CHEMBL1760953 | N-(2-(3-((4-(4-fluorobenzoyl)piper...)
Show SMILES COc1ccc2c(CN3CCC(CC3)C(=O)c3ccc(F)cc3)cn(CCNC(C)=O)c2n1
Show InChI InChI=1S/C25H29FN4O3/c1-17(31)27-11-14-30-16-20(22-7-8-23(33-2)28-25(22)30)15-29-12-9-19(10-13-29)24(32)18-3-5-21(26)6-4-18/h3-8,16,19H,9-15H2,1-2H3,(H,27,31)
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7.44E+3n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340334
PNG
(CHEMBL1760954 | N-(2-(6-methoxy-3-((methylamino)me...)
Show SMILES CNCc1cn(CCNC(C)=O)c2nc(OC)ccc12
Show InChI InChI=1S/C14H20N4O2/c1-10(19)16-6-7-18-9-11(8-15-2)12-4-5-13(20-3)17-14(12)18/h4-5,9,15H,6-8H2,1-3H3,(H,16,19)
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8.30E+3n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340336
PNG
(CHEMBL1760953 | N-(2-(3-((4-(4-fluorobenzoyl)piper...)
Show SMILES COc1ccc2c(CN3CCC(CC3)C(=O)c3ccc(F)cc3)cn(CCNC(C)=O)c2n1
Show InChI InChI=1S/C25H29FN4O3/c1-17(31)27-11-14-30-16-20(22-7-8-23(33-2)28-25(22)30)15-29-12-9-19(10-13-29)24(32)18-3-5-21(26)6-4-18/h3-8,16,19H,9-15H2,1-2H3,(H,27,31)
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9.49E+3n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340332
PNG
(CHEMBL1760951 | N-(2-(6-methoxy-3-(morpholinomethy...)
Show SMILES COc1ccc2c(CN3CCOCC3)cn(CCNC(C)=O)c2n1
Show InChI InChI=1S/C17H24N4O3/c1-13(22)18-5-6-21-12-14(11-20-7-9-24-10-8-20)15-3-4-16(23-2)19-17(15)21/h3-4,12H,5-11H2,1-2H3,(H,18,22)
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>1.00E+4n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340337
PNG
(CHEMBL1760948 | N-(2-(3-((dimethylamino)methyl)-6-...)
Show SMILES COc1ccc2c(CN(C)C)cn(CCNC(C)=O)c2n1
Show InChI InChI=1S/C15H22N4O2/c1-11(20)16-7-8-19-10-12(9-18(2)3)13-5-6-14(21-4)17-15(13)19/h5-6,10H,7-9H2,1-4H3,(H,16,20)
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>1.00E+4n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340337
PNG
(CHEMBL1760948 | N-(2-(3-((dimethylamino)methyl)-6-...)
Show SMILES COc1ccc2c(CN(C)C)cn(CCNC(C)=O)c2n1
Show InChI InChI=1S/C15H22N4O2/c1-11(20)16-7-8-19-10-12(9-18(2)3)13-5-6-14(21-4)17-15(13)19/h5-6,10H,7-9H2,1-4H3,(H,16,20)
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>1.00E+4n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50340335
PNG
(CHEMBL1760949 | N-(2-(3-((benzyl(methyl)amino)meth...)
Show SMILES COc1ccc2c(CN(C)Cc3ccccc3)cn(CCNC(C)=O)c2n1
Show InChI InChI=1S/C21H26N4O2/c1-16(26)22-11-12-25-15-18(19-9-10-20(27-3)23-21(19)25)14-24(2)13-17-7-5-4-6-8-17/h4-10,15H,11-14H2,1-3H3,(H,22,26)
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1.05E+4n/an/an/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 2316-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.097
BindingDB Entry DOI: 10.7270/Q27H1JWM
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM339807
PNG
(US9757364, Compound 11)
Show SMILES COc1cc(OC)cc(c1)N(CCCO)c1ccc2ncc(-c3cnn(C)c3)c(Cl)c2n1
Show InChI InChI=1S/C23H24ClN5O3/c1-28-14-15(12-26-28)19-13-25-20-5-6-21(27-23(20)22(19)24)29(7-4-8-30)16-9-17(31-2)11-18(10-16)32-3/h5-6,9-14,30H,4,7-8H2,1-3H3
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n/an/a 0.126n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM339838
PNG
(US9757364, Compound 39)
Show SMILES COc1cc(OC)cc(c1)N(Cc1c[nH]cn1)c1ccc2ncc(cc2n1)-c1cnn(C)c1
Show InChI InChI=1S/C24H23N7O2/c1-30-13-17(11-28-30)16-6-23-22(26-10-16)4-5-24(29-23)31(14-18-12-25-15-27-18)19-7-20(32-2)9-21(8-19)33-3/h4-13,15H,14H2,1-3H3,(H,25,27)
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n/an/a 0.355n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM339871
PNG
(US9757364, Compound 55)
Show SMILES COc1cc(OC)c(F)c(c1)N(Cc1cc[nH]n1)c1ccc2ncc(cc2n1)-c1cnn(C)c1
Show InChI InChI=1S/C24H22FN7O2/c1-31-13-16(12-28-31)15-8-20-19(26-11-15)4-5-23(29-20)32(14-17-6-7-27-30-17)21-9-18(33-2)10-22(34-3)24(21)25/h4-13H,14H2,1-3H3,(H,27,30)
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n/an/a 0.417n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM339823
PNG
(US9757364, Compound 16)
Show SMILES COc1cc(OC)cc(c1)N(Cc1ncc[nH]1)c1ccc2ncc(-c3cnn(C)c3)c(Cl)c2n1
Show InChI InChI=1S/C24H22ClN7O2/c1-31-13-15(11-29-31)19-12-28-20-4-5-22(30-24(20)23(19)25)32(14-21-26-6-7-27-21)16-8-17(33-2)10-18(9-16)34-3/h4-13H,14H2,1-3H3,(H,26,27)
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n/an/a 0.447n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM339807
PNG
(US9757364, Compound 11)
Show SMILES COc1cc(OC)cc(c1)N(CCCO)c1ccc2ncc(-c3cnn(C)c3)c(Cl)c2n1
Show InChI InChI=1S/C23H24ClN5O3/c1-28-14-15(12-26-28)19-13-25-20-5-6-21(27-23(20)22(19)24)29(7-4-8-30)16-9-17(31-2)11-18(10-16)32-3/h5-6,9-14,30H,4,7-8H2,1-3H3
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n/an/a 0.501n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM339803
PNG
(US9757364, Compound 10)
Show SMILES COc1cc(OC)cc(c1)N(Cc1ncc[nH]1)c1ccc2ncc(cc2n1)-c1cnn(C)c1
Show InChI InChI=1S/C24H23N7O2/c1-30-14-17(13-28-30)16-8-22-21(27-12-16)4-5-24(29-22)31(15-23-25-6-7-26-23)18-9-19(32-2)11-20(10-18)33-3/h4-14H,15H2,1-3H3,(H,25,26)
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n/an/a 0.501n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM339869
PNG
(US9757364, Compound 57)
Show SMILES COc1cc(OC)c(F)c(c1)N(CCCC#N)c1ccc2ncc(cc2n1)-c1cnn(C)c1
Show InChI InChI=1S/C24H23FN6O2/c1-30-15-17(14-28-30)16-10-20-19(27-13-16)6-7-23(29-20)31(9-5-4-8-26)21-11-18(32-2)12-22(33-3)24(21)25/h6-7,10-15H,4-5,9H2,1-3H3
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n/an/a 0.550n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM339822
PNG
(US9757364, Compound 15)
Show SMILES COc1cc(OC)cc(c1)N(CCO)c1ccc2ncc(-c3cnn(C)c3)c(Cl)c2n1
Show InChI InChI=1S/C22H22ClN5O3/c1-27-13-14(11-25-27)18-12-24-19-4-5-20(26-22(19)21(18)23)28(6-7-29)15-8-16(30-2)10-17(9-15)31-3/h4-5,8-13,29H,6-7H2,1-3H3
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n/an/a 0.550n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM339823
PNG
(US9757364, Compound 16)
Show SMILES COc1cc(OC)cc(c1)N(Cc1ncc[nH]1)c1ccc2ncc(-c3cnn(C)c3)c(Cl)c2n1
Show InChI InChI=1S/C24H22ClN7O2/c1-31-13-15(11-29-31)19-12-28-20-4-5-22(30-24(20)23(19)25)32(14-21-26-6-7-27-21)16-8-17(33-2)10-18(9-16)34-3/h4-13H,14H2,1-3H3,(H,26,27)
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n/an/a 0.575n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM339838
PNG
(US9757364, Compound 39)
Show SMILES COc1cc(OC)cc(c1)N(Cc1c[nH]cn1)c1ccc2ncc(cc2n1)-c1cnn(C)c1
Show InChI InChI=1S/C24H23N7O2/c1-30-13-17(11-28-30)16-6-23-22(26-10-16)4-5-24(29-23)31(14-18-12-25-15-27-18)19-7-20(32-2)9-21(8-19)33-3/h4-13,15H,14H2,1-3H3,(H,25,27)
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n/an/a 0.603n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM339803
PNG
(US9757364, Compound 10)
Show SMILES COc1cc(OC)cc(c1)N(Cc1ncc[nH]1)c1ccc2ncc(cc2n1)-c1cnn(C)c1
Show InChI InChI=1S/C24H23N7O2/c1-30-14-17(13-28-30)16-8-22-21(27-12-16)4-5-24(29-22)31(15-23-25-6-7-26-23)18-9-19(32-2)11-20(10-18)33-3/h4-14H,15H2,1-3H3,(H,25,26)
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n/an/a 0.631n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM339804
PNG
(US9757364, Compound 2)
Show SMILES COc1cc(OC)cc(c1)N(CCCO)c1ccc2ncc(cc2n1)-c1cnn(C)c1
Show InChI InChI=1S/C23H25N5O3/c1-27-15-17(14-25-27)16-9-22-21(24-13-16)5-6-23(26-22)28(7-4-8-29)18-10-19(30-2)12-20(11-18)31-3/h5-6,9-15,29H,4,7-8H2,1-3H3
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n/an/a 0.631n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM339825
PNG
(US9757364, Compound 31)
Show SMILES COc1cc(OC)cc(c1)N(C1CCNCC1)c1ccc2ncc(cc2n1)-c1cnn(C)c1
Show InChI InChI=1S/C25H28N6O2/c1-30-16-18(15-28-30)17-10-24-23(27-14-17)4-5-25(29-24)31(19-6-8-26-9-7-19)20-11-21(32-2)13-22(12-20)33-3/h4-5,10-16,19,26H,6-9H2,1-3H3
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n/an/a 0.676n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM339848
PNG
(US9757364, Compound 47)
Show SMILES COc1cc(OC)cc(c1)N(Cc1nnc[nH]1)c1ccc2ncc(cc2n1)-c1cnn(C)c1
Show InChI InChI=1S/C23H22N8O2/c1-30-12-16(11-27-30)15-6-21-20(24-10-15)4-5-23(28-21)31(13-22-25-14-26-29-22)17-7-18(32-2)9-19(8-17)33-3/h4-12,14H,13H2,1-3H3,(H,25,26,29)
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n/an/a 0.692n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM339822
PNG
(US9757364, Compound 15)
Show SMILES COc1cc(OC)cc(c1)N(CCO)c1ccc2ncc(-c3cnn(C)c3)c(Cl)c2n1
Show InChI InChI=1S/C22H22ClN5O3/c1-27-13-14(11-25-27)18-12-24-19-4-5-20(26-22(19)21(18)23)28(6-7-29)15-8-16(30-2)10-17(9-15)31-3/h4-5,8-13,29H,6-7H2,1-3H3
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n/an/a 0.724n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM339838
PNG
(US9757364, Compound 39)
Show SMILES COc1cc(OC)cc(c1)N(Cc1c[nH]cn1)c1ccc2ncc(cc2n1)-c1cnn(C)c1
Show InChI InChI=1S/C24H23N7O2/c1-30-13-17(11-28-30)16-6-23-22(26-10-16)4-5-24(29-23)31(14-18-12-25-15-27-18)19-7-20(32-2)9-21(8-19)33-3/h4-13,15H,14H2,1-3H3,(H,25,27)
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n/an/a 0.724n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR3 (h) (40 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM339822
PNG
(US9757364, Compound 15)
Show SMILES COc1cc(OC)cc(c1)N(CCO)c1ccc2ncc(-c3cnn(C)c3)c(Cl)c2n1
Show InChI InChI=1S/C22H22ClN5O3/c1-27-13-14(11-25-27)18-12-24-19-4-5-20(26-22(19)21(18)23)28(6-7-29)15-8-16(30-2)10-17(9-15)31-3/h4-5,8-13,29H,6-7H2,1-3H3
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n/an/a 0.759n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR2 (h) (150 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Tri...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM339807
PNG
(US9757364, Compound 11)
Show SMILES COc1cc(OC)cc(c1)N(CCCO)c1ccc2ncc(-c3cnn(C)c3)c(Cl)c2n1
Show InChI InChI=1S/C23H24ClN5O3/c1-28-14-15(12-26-28)19-13-25-20-5-6-21(27-23(20)22(19)24)29(7-4-8-30)16-9-17(31-2)11-18(10-16)32-3/h5-6,9-14,30H,4,7-8H2,1-3H3
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n/an/a 0.794n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent


Assay Description
In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...


US Patent US9757364 (2017)

More data for this
Ligand-Target Pair
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