BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 243 hits with Last Name = 'lejeune' and Initial = 'c'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM21398
PNG
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
2.20n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50001884
PNG
(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12
Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
6.70n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at serotonin 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptor D2L/neurotensin receptor NTS1


(Homo sapiens (Human))
BDBM21398
PNG
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
8.5n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D2L expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50001884
PNG
(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12
Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
18n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50040250
PNG
(8-Chloro-6-(4-methyl-piperazin-1-yl)-11H-benzo[e]p...)
Show SMILES CN1CCN(CC1)C1=Nc2cccnc2Nc2ccc(Cl)cc12
Show InChI InChI=1S/C17H18ClN5/c1-22-7-9-23(10-8-22)17-13-11-12(18)4-5-14(13)20-16-15(21-17)3-2-6-19-16/h2-6,11H,7-10H2,1H3,(H,19,20)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
24n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50120943
PNG
(6-(4-Cyclohexyl-piperazin-1-yl)-8-methyl-11H-benzo...)
Show SMILES Cc1ccc2Nc3ncccc3N=C(N3CCN(CC3)C3CCCCC3)c2c1
Show InChI InChI=1S/C23H29N5/c1-17-9-10-20-19(16-17)23(26-21-8-5-11-24-22(21)25-20)28-14-12-27(13-15-28)18-6-3-2-4-7-18/h5,8-11,16,18H,2-4,6-7,12-15H2,1H3,(H,24,25)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
33n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50120934
PNG
((8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-(8-methyl-...)
Show SMILES Cc1ccc2Nc3ncccc3N=C(NC3CC4CCC(C3)N4Cc3ccccc3)c2c1
Show InChI InChI=1S/C27H29N5/c1-18-9-12-24-23(14-18)26(31-25-8-5-13-28-27(25)30-24)29-20-15-21-10-11-22(16-20)32(21)17-19-6-3-2-4-7-19/h2-9,12-14,20-22H,10-11,15-17H2,1H3,(H,28,30)(H,29,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
34n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50120925
PNG
(8-Chloro-6-(4-cyclohexyl-piperazin-1-yl)-11H-benzo...)
Show SMILES Clc1ccc2Nc3ncccc3N=C(N3CCN(CC3)C3CCCCC3)c2c1
Show InChI InChI=1S/C22H26ClN5/c23-16-8-9-19-18(15-16)22(26-20-7-4-10-24-21(20)25-19)28-13-11-27(12-14-28)17-5-2-1-3-6-17/h4,7-10,15,17H,1-3,5-6,11-14H2,(H,24,25)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
34n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50040250
PNG
(8-Chloro-6-(4-methyl-piperazin-1-yl)-11H-benzo[e]p...)
Show SMILES CN1CCN(CC1)C1=Nc2cccnc2Nc2ccc(Cl)cc12
Show InChI InChI=1S/C17H18ClN5/c1-22-7-9-23(10-8-22)17-13-11-12(18)4-5-14(13)20-16-15(21-17)3-2-6-19-16/h2-6,11H,7-10H2,1H3,(H,19,20)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
35n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at serotonin 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50120921
PNG
(8-Methyl-6-(4-phenethyl-piperazin-1-yl)-11H-benzo[...)
Show SMILES Cc1ccc2Nc3ncccc3N=C(N3CCN(CCc4ccccc4)CC3)c2c1
Show InChI InChI=1S/C25H27N5/c1-19-9-10-22-21(18-19)25(28-23-8-5-12-26-24(23)27-22)30-16-14-29(15-17-30)13-11-20-6-3-2-4-7-20/h2-10,12,18H,11,13-17H2,1H3,(H,26,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
36n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50120938
PNG
((8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-(8-chloro-...)
Show SMILES Clc1ccc2Nc3ncccc3N=C(NC3CC4CCC(C3)N4Cc3ccccc3)c2c1
Show InChI InChI=1S/C26H26ClN5/c27-18-8-11-23-22(13-18)25(31-24-7-4-12-28-26(24)30-23)29-19-14-20-9-10-21(15-19)32(20)16-17-5-2-1-3-6-17/h1-8,11-13,19-21H,9-10,14-16H2,(H,28,30)(H,29,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
36n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50040245
PNG
(8-Methyl-6-(4-methyl-piperazin-1-yl)-11H-benzo[e]p...)
Show SMILES CN1CCN(CC1)C1=Nc2cccnc2Nc2ccc(C)cc12
Show InChI InChI=1S/C18H21N5/c1-13-5-6-15-14(12-13)18(23-10-8-22(2)9-11-23)21-16-4-3-7-19-17(16)20-15/h3-7,12H,8-11H2,1-2H3,(H,19,20)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
36n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50040245
PNG
(8-Methyl-6-(4-methyl-piperazin-1-yl)-11H-benzo[e]p...)
Show SMILES CN1CCN(CC1)C1=Nc2cccnc2Nc2ccc(C)cc12
Show InChI InChI=1S/C18H21N5/c1-13-5-6-15-14(12-13)18(23-10-8-22(2)9-11-23)21-16-4-3-7-19-17(16)20-15/h3-7,12H,8-11H2,1-2H3,(H,19,20)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
37n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at serotonin 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50120921
PNG
(8-Methyl-6-(4-phenethyl-piperazin-1-yl)-11H-benzo[...)
Show SMILES Cc1ccc2Nc3ncccc3N=C(N3CCN(CCc4ccccc4)CC3)c2c1
Show InChI InChI=1S/C25H27N5/c1-19-9-10-22-21(18-19)25(28-23-8-5-12-26-24(23)27-22)30-16-14-29(15-17-30)13-11-20-6-3-2-4-7-20/h2-10,12,18H,11,13-17H2,1H3,(H,26,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
37n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50120945
PNG
(8-Chloro-6-(4-phenethyl-piperazin-1-yl)-11H-benzo[...)
Show SMILES Clc1ccc2Nc3ncccc3N=C(N3CCN(CCc4ccccc4)CC3)c2c1
Show InChI InChI=1S/C24H24ClN5/c25-19-8-9-21-20(17-19)24(28-22-7-4-11-26-23(22)27-21)30-15-13-29(14-16-30)12-10-18-5-2-1-3-6-18/h1-9,11,17H,10,12-16H2,(H,26,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
40n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50120932
PNG
((1-Benzyl-piperidin-4-yl)-(8-methyl-11H-benzo[e]py...)
Show SMILES Cc1ccc2Nc3ncccc3N=C(NC3CCN(Cc4ccccc4)CC3)c2c1
Show InChI InChI=1S/C25H27N5/c1-18-9-10-22-21(16-18)24(29-23-8-5-13-26-25(23)28-22)27-20-11-14-30(15-12-20)17-19-6-3-2-4-7-19/h2-10,13,16,20H,11-12,14-15,17H2,1H3,(H,26,28)(H,27,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
46n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50120925
PNG
(8-Chloro-6-(4-cyclohexyl-piperazin-1-yl)-11H-benzo...)
Show SMILES Clc1ccc2Nc3ncccc3N=C(N3CCN(CC3)C3CCCCC3)c2c1
Show InChI InChI=1S/C22H26ClN5/c23-16-8-9-19-18(15-16)22(26-20-7-4-10-24-21(20)25-19)28-13-11-27(12-14-28)17-5-2-1-3-6-17/h4,7-10,15,17H,1-3,5-6,11-14H2,(H,24,25)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
48n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50120932
PNG
((1-Benzyl-piperidin-4-yl)-(8-methyl-11H-benzo[e]py...)
Show SMILES Cc1ccc2Nc3ncccc3N=C(NC3CCN(Cc4ccccc4)CC3)c2c1
Show InChI InChI=1S/C25H27N5/c1-18-9-10-22-21(16-18)24(29-23-8-5-13-26-25(23)28-22)27-20-11-14-30(15-12-20)17-19-6-3-2-4-7-19/h2-10,13,16,20H,11-12,14-15,17H2,1H3,(H,26,28)(H,27,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
48n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM21398
PNG
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
49n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at serotonin 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50120939
PNG
((1-Benzyl-piperidin-4-yl)-(8-chloro-11H-benzo[e]py...)
Show SMILES Clc1ccc2Nc3ncccc3N=C(NC3CCN(Cc4ccccc4)CC3)c2c1
Show InChI InChI=1S/C24H24ClN5/c25-18-8-9-21-20(15-18)23(29-22-7-4-12-26-24(22)28-21)27-19-10-13-30(14-11-19)16-17-5-2-1-3-6-17/h1-9,12,15,19H,10-11,13-14,16H2,(H,26,28)(H,27,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
81n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50120943
PNG
(6-(4-Cyclohexyl-piperazin-1-yl)-8-methyl-11H-benzo...)
Show SMILES Cc1ccc2Nc3ncccc3N=C(N3CCN(CC3)C3CCCCC3)c2c1
Show InChI InChI=1S/C23H29N5/c1-17-9-10-20-19(16-17)23(26-21-8-5-11-24-22(21)25-20)28-14-12-27(13-15-28)18-6-3-2-4-7-18/h5,8-11,16,18H,2-4,6-7,12-15H2,1H3,(H,24,25)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
84n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50120939
PNG
((1-Benzyl-piperidin-4-yl)-(8-chloro-11H-benzo[e]py...)
Show SMILES Clc1ccc2Nc3ncccc3N=C(NC3CCN(Cc4ccccc4)CC3)c2c1
Show InChI InChI=1S/C24H24ClN5/c25-18-8-9-21-20(15-18)23(29-22-7-4-12-26-24(22)28-21)27-19-10-13-30(14-11-19)16-17-5-2-1-3-6-17/h1-9,12,15,19H,10-11,13-14,16H2,(H,26,28)(H,27,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
89n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50120945
PNG
(8-Chloro-6-(4-phenethyl-piperazin-1-yl)-11H-benzo[...)
Show SMILES Clc1ccc2Nc3ncccc3N=C(N3CCN(CCc4ccccc4)CC3)c2c1
Show InChI InChI=1S/C24H24ClN5/c25-19-8-9-21-20(17-19)24(28-22-7-4-11-26-23(22)27-21)30-15-13-29(14-16-30)12-10-18-5-2-1-3-6-18/h1-9,11,17H,10,12-16H2,(H,26,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
103n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50120928
PNG
(6-(4-Benzyl-piperazin-1-yl)-8-chloro-11H-benzo[e]p...)
Show SMILES Clc1ccc2Nc3ncccc3N=C(N3CCN(Cc4ccccc4)CC3)c2c1
Show InChI InChI=1S/C23H22ClN5/c24-18-8-9-20-19(15-18)23(27-21-7-4-10-25-22(21)26-20)29-13-11-28(12-14-29)16-17-5-2-1-3-6-17/h1-10,15H,11-14,16H2,(H,25,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
109n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50120938
PNG
((8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-(8-chloro-...)
Show SMILES Clc1ccc2Nc3ncccc3N=C(NC3CC4CCC(C3)N4Cc3ccccc3)c2c1
Show InChI InChI=1S/C26H26ClN5/c27-18-8-11-23-22(13-18)25(31-24-7-4-12-28-26(24)30-23)29-19-14-20-9-10-21(15-19)32(20)16-17-5-2-1-3-6-17/h1-8,11-13,19-21H,9-10,14-16H2,(H,28,30)(H,29,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
115n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50120941
PNG
((8-Chloro-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6...)
Show SMILES CN1CCC(CC1)NC1=Nc2cccnc2Nc2ccc(Cl)cc12
Show InChI InChI=1S/C18H20ClN5/c1-24-9-6-13(7-10-24)21-17-14-11-12(19)4-5-15(14)22-18-16(23-17)3-2-8-20-18/h2-5,8,11,13H,6-7,9-10H2,1H3,(H,20,22)(H,21,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
123n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50120934
PNG
((8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-(8-methyl-...)
Show SMILES Cc1ccc2Nc3ncccc3N=C(NC3CC4CCC(C3)N4Cc3ccccc3)c2c1
Show InChI InChI=1S/C27H29N5/c1-18-9-12-24-23(14-18)26(31-25-8-5-13-28-27(25)30-24)29-20-15-21-10-11-22(16-20)32(21)17-19-6-3-2-4-7-19/h2-9,12-14,20-22H,10-11,15-17H2,1H3,(H,28,30)(H,29,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
131n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50120935
PNG
((8-Methyl-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6...)
Show SMILES CN1CCC(CC1)NC1=Nc2cccnc2Nc2ccc(C)cc12
Show InChI InChI=1S/C19H23N5/c1-13-5-6-16-15(12-13)18(21-14-7-10-24(2)11-8-14)23-17-4-3-9-20-19(17)22-16/h3-6,9,12,14H,7-8,10-11H2,1-2H3,(H,20,22)(H,21,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
132n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptor D2L/neurotensin receptor NTS1


(Homo sapiens (Human))
BDBM50120938
PNG
((8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-(8-chloro-...)
Show SMILES Clc1ccc2Nc3ncccc3N=C(NC3CC4CCC(C3)N4Cc3ccccc3)c2c1
Show InChI InChI=1S/C26H26ClN5/c27-18-8-11-23-22(13-18)25(31-24-7-4-12-28-26(24)30-23)29-19-14-20-9-10-21(15-19)32(20)16-17-5-2-1-3-6-17/h1-8,11-13,19-21H,9-10,14-16H2,(H,28,30)(H,29,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
136n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D2L expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptor D2L/neurotensin receptor NTS1


(Homo sapiens (Human))
BDBM50120934
PNG
((8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-(8-methyl-...)
Show SMILES Cc1ccc2Nc3ncccc3N=C(NC3CC4CCC(C3)N4Cc3ccccc3)c2c1
Show InChI InChI=1S/C27H29N5/c1-18-9-12-24-23(14-18)26(31-25-8-5-13-28-27(25)30-24)29-20-15-21-10-11-22(16-20)32(21)17-19-6-3-2-4-7-19/h2-9,12-14,20-22H,10-11,15-17H2,1H3,(H,28,30)(H,29,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
149n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D2L expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50120944
PNG
(CHEMBL149493 | N,N-Dimethyl-N'-(8-methyl-11H-benzo...)
Show SMILES CN(C)CCNC1=Nc2cccnc2Nc2ccc(C)cc12
Show InChI InChI=1S/C17H21N5/c1-12-6-7-14-13(11-12)16(19-9-10-22(2)3)21-15-5-4-8-18-17(15)20-14/h4-8,11H,9-10H2,1-3H3,(H,18,20)(H,19,21)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
150n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50291998
PNG
(8-Chloro-6-(4-methyl-[1,4]diazepan-1-yl)-11H-benzo...)
Show SMILES CN1CCCN(CC1)C1=Nc2cccnc2Nc2ccc(Cl)cc12
Show InChI InChI=1S/C18H20ClN5/c1-23-8-3-9-24(11-10-23)18-14-12-13(19)5-6-15(14)21-17-16(22-18)4-2-7-20-17/h2,4-7,12H,3,8-11H2,1H3,(H,20,21)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
163n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50291998
PNG
(8-Chloro-6-(4-methyl-[1,4]diazepan-1-yl)-11H-benzo...)
Show SMILES CN1CCCN(CC1)C1=Nc2cccnc2Nc2ccc(Cl)cc12
Show InChI InChI=1S/C18H20ClN5/c1-23-8-3-9-24(11-10-23)18-14-12-13(19)5-6-15(14)21-17-16(22-18)4-2-7-20-17/h2,4-7,12H,3,8-11H2,1H3,(H,20,21)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
164n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at serotonin 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptor D2L/neurotensin receptor NTS1


(Homo sapiens (Human))
BDBM50120932
PNG
((1-Benzyl-piperidin-4-yl)-(8-methyl-11H-benzo[e]py...)
Show SMILES Cc1ccc2Nc3ncccc3N=C(NC3CCN(Cc4ccccc4)CC3)c2c1
Show InChI InChI=1S/C25H27N5/c1-18-9-10-22-21(16-18)24(29-23-8-5-13-26-25(23)28-22)27-20-11-14-30(15-12-20)17-19-6-3-2-4-7-19/h2-10,13,16,20H,11-12,14-15,17H2,1H3,(H,26,28)(H,27,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
183n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D2L expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50120929
PNG
(6-(4-Benzyl-piperazin-1-yl)-8-methyl-11H-benzo[e]p...)
Show SMILES Cc1ccc2Nc3ncccc3N=C(N3CCN(Cc4ccccc4)CC3)c2c1
Show InChI InChI=1S/C24H25N5/c1-18-9-10-21-20(16-18)24(27-22-8-5-11-25-23(22)26-21)29-14-12-28(13-15-29)17-19-6-3-2-4-7-19/h2-11,16H,12-15,17H2,1H3,(H,25,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
183n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptor D2L/neurotensin receptor NTS1


(Homo sapiens (Human))
BDBM50120939
PNG
((1-Benzyl-piperidin-4-yl)-(8-chloro-11H-benzo[e]py...)
Show SMILES Clc1ccc2Nc3ncccc3N=C(NC3CCN(Cc4ccccc4)CC3)c2c1
Show InChI InChI=1S/C24H24ClN5/c25-18-8-9-21-20(15-18)23(29-22-7-4-12-26-24(22)28-21)27-19-10-13-30(14-11-19)16-17-5-2-1-3-6-17/h1-9,12,15,19H,10-11,13-14,16H2,(H,26,28)(H,27,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
183n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D2L expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50120923
PNG
((8-Chloro-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6...)
Show SMILES Clc1ccc2Nc3ncccc3N=C(NCCN3CCCC3)c2c1
Show InChI InChI=1S/C18H20ClN5/c19-13-5-6-15-14(12-13)17(21-8-11-24-9-1-2-10-24)23-16-4-3-7-20-18(16)22-15/h3-7,12H,1-2,8-11H2,(H,20,22)(H,21,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
250n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50120936
PNG
(8-Methyl-6-(4-methyl-[1,4]diazepan-1-yl)-11H-benzo...)
Show SMILES CN1CCCN(CC1)C1=Nc2cccnc2Nc2ccc(C)cc12
Show InChI InChI=1S/C19H23N5/c1-14-6-7-16-15(13-14)19(24-10-4-9-23(2)11-12-24)22-17-5-3-8-20-18(17)21-16/h3,5-8,13H,4,9-12H2,1-2H3,(H,20,21)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
303n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50120923
PNG
((8-Chloro-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6...)
Show SMILES Clc1ccc2Nc3ncccc3N=C(NCCN3CCCC3)c2c1
Show InChI InChI=1S/C18H20ClN5/c19-13-5-6-15-14(12-13)17(21-8-11-24-9-1-2-10-24)23-16-4-3-7-20-18(16)22-15/h3-7,12H,1-2,8-11H2,(H,20,22)(H,21,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
341n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50120936
PNG
(8-Methyl-6-(4-methyl-[1,4]diazepan-1-yl)-11H-benzo...)
Show SMILES CN1CCCN(CC1)C1=Nc2cccnc2Nc2ccc(C)cc12
Show InChI InChI=1S/C19H23N5/c1-14-6-7-16-15(13-14)19(24-10-4-9-23(2)11-12-24)22-17-5-3-8-20-18(17)21-16/h3,5-8,13H,4,9-12H2,1-2H3,(H,20,21)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
356n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50120930
PNG
((8-Chloro-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6...)
Show SMILES Clc1ccc2Nc3ncccc3N=C(NCCN3CCCCC3)c2c1
Show InChI InChI=1S/C19H22ClN5/c20-14-6-7-16-15(13-14)18(22-9-12-25-10-2-1-3-11-25)24-17-5-4-8-21-19(17)23-16/h4-8,13H,1-3,9-12H2,(H,21,23)(H,22,24)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
357n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptor D2L/neurotensin receptor NTS1


(Homo sapiens (Human))
BDBM50001884
PNG
(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12
Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
372n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D2L expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50120941
PNG
((8-Chloro-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6...)
Show SMILES CN1CCC(CC1)NC1=Nc2cccnc2Nc2ccc(Cl)cc12
Show InChI InChI=1S/C18H20ClN5/c1-24-9-6-13(7-10-24)21-17-14-11-12(19)4-5-15(14)22-18-16(23-17)3-2-8-20-18/h2-5,8,11,13H,6-7,9-10H2,1H3,(H,20,22)(H,21,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
393n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50120935
PNG
((8-Methyl-11H-benzo[e]pyrido[3,2-b][1,4]diazepin-6...)
Show SMILES CN1CCC(CC1)NC1=Nc2cccnc2Nc2ccc(C)cc12
Show InChI InChI=1S/C19H23N5/c1-13-5-6-16-15(12-13)18(21-14-7-10-24(2)11-8-14)23-17-4-3-9-20-19(17)22-16/h3-6,9,12,14H,7-8,10-11H2,1-2H3,(H,20,22)(H,21,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
510n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D4 expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptor D2L/neurotensin receptor NTS1


(Homo sapiens (Human))
BDBM50120925
PNG
(8-Chloro-6-(4-cyclohexyl-piperazin-1-yl)-11H-benzo...)
Show SMILES Clc1ccc2Nc3ncccc3N=C(N3CCN(CC3)C3CCCCC3)c2c1
Show InChI InChI=1S/C22H26ClN5/c23-16-8-9-19-18(15-16)22(26-20-7-4-10-24-21(20)25-19)28-13-11-27(12-14-28)17-5-2-1-3-6-17/h4,7-10,15,17H,1-3,5-6,11-14H2,(H,24,25)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
571n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D2L expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptor D2L/neurotensin receptor NTS1


(Homo sapiens (Human))
BDBM50120921
PNG
(8-Methyl-6-(4-phenethyl-piperazin-1-yl)-11H-benzo[...)
Show SMILES Cc1ccc2Nc3ncccc3N=C(N3CCN(CCc4ccccc4)CC3)c2c1
Show InChI InChI=1S/C25H27N5/c1-19-9-10-22-21(18-19)25(28-23-8-5-12-26-24(23)27-22)30-16-14-29(15-17-30)13-11-20-6-3-2-4-7-20/h2-10,12,18H,11,13-17H2,1H3,(H,26,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
635n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D2L expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Dopamine receptor D2L/neurotensin receptor NTS1


(Homo sapiens (Human))
BDBM50120945
PNG
(8-Chloro-6-(4-phenethyl-piperazin-1-yl)-11H-benzo[...)
Show SMILES Clc1ccc2Nc3ncccc3N=C(N3CCN(CCc4ccccc4)CC3)c2c1
Show InChI InChI=1S/C24H24ClN5/c25-19-8-9-21-20(17-19)24(28-22-7-4-11-26-23(22)27-21)30-15-13-29(14-16-30)12-10-18-5-2-1-3-6-18/h1-9,11,17H,10,12-16H2,(H,26,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
892n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at human cloned Dopamine receptor D2L expressed in Sf9 cell membranes


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50120928
PNG
(6-(4-Benzyl-piperazin-1-yl)-8-chloro-11H-benzo[e]p...)
Show SMILES Clc1ccc2Nc3ncccc3N=C(N3CCN(Cc4ccccc4)CC3)c2c1
Show InChI InChI=1S/C23H22ClN5/c24-18-8-9-20-19(15-18)23(27-21-7-4-10-25-22(21)26-20)29-13-11-28(12-14-29)16-17-5-2-1-3-6-17/h1-10,15H,11-14,16H2,(H,25,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50120924
PNG
(8-Methyl-6-(4-phenyl-piperazin-1-yl)-11H-benzo[e]p...)
Show SMILES Cc1ccc2Nc3ncccc3N=C(N3CCN(CC3)c3ccccc3)c2c1
Show InChI InChI=1S/C23H23N5/c1-17-9-10-20-19(16-17)23(26-21-8-5-11-24-22(21)25-20)28-14-12-27(13-15-28)18-6-3-2-4-7-18/h2-11,16H,12-15H2,1H3,(H,24,25)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50120933
PNG
(CHEMBL345964 | N,N-Dimethyl-N'-(8-methyl-11H-benzo...)
Show SMILES CN(C)CCCNC1=Nc2cccnc2Nc2ccc(C)cc12
Show InChI InChI=1S/C18H23N5/c1-13-7-8-15-14(12-13)17(19-10-5-11-23(2)3)22-16-6-4-9-20-18(16)21-15/h4,6-9,12H,5,10-11H2,1-3H3,(H,19,22)(H,20,21)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



University of Liège

Curated by ChEMBL


Assay Description
In vitro binding affinity at 5-hydroxytryptamine 2A receptor in rat cortical membrane


J Med Chem 45: 5136-49 (2002)

More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 243 total )  |  Next  |  Last  >>
Jump to: