Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50089890![]() (4-Amino-2-oxa-bicyclo[3.1.0]hexane-4,6-dicarboxyli...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50089897![]() (4-Amino-2-thia-bicyclo[3.1.0]hexane-4,6-dicarboxyl...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50089890![]() (4-Amino-2-oxa-bicyclo[3.1.0]hexane-4,6-dicarboxyli...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 3 (mGluR-3). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50089897![]() (4-Amino-2-thia-bicyclo[3.1.0]hexane-4,6-dicarboxyl...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 3 (mGluR-3). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50056272![]() ((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50062522![]() ((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 3 (mGluR-3). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
GRIA2 (Homo sapiens (Human)) | BDBM50002370![]() ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 2 (GluR2) expressed in Sf 9 insect cells | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA3 (RAT) | BDBM50002368![]() ((R,S)-2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)p...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by PDSP Ki Database | Chirality 13: 523-32 (2001) Article DOI: 10.1002/chir.1172 BindingDB Entry DOI: 10.7270/Q2Z31X6K | ||||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic AMPA (Homo sapiens (Human)) | BDBM50002370![]() ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 3 (GluR3) expressed in Sf 9 insect cells | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50062522![]() ((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Antagonist potency against cloned Metabotropic glutamate receptor 2 | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA1 (Homo sapiens (Human)) | BDBM50002370![]() ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 1 (GluR1) expressed in Sf 9 insect cells | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA3 (RAT) | BDBM50316376![]() ((S)-2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)pro...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by PDSP Ki Database | Chirality 13: 523-32 (2001) Article DOI: 10.1002/chir.1172 BindingDB Entry DOI: 10.7270/Q2Z31X6K | ||||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50084137![]() (2-Methyl-6-(phenylethynyl)pyridine | 2-Methyl-6-ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | Purchase CHEBI CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned metabotropic glutamate receptor 5 | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50056272![]() ((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 3 (mGluR-3). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
GRIA3 (RAT) | BDBM2219![]() ((S)-Demethyl-ACPA | Demethyl-ACPA) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by PDSP Ki Database | Chirality 13: 523-32 (2001) Article DOI: 10.1002/chir.1172 BindingDB Entry DOI: 10.7270/Q2Z31X6K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic AMPA (Homo sapiens (Human)) | BDBM50002370![]() ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 4 (GluR4) expressed in Sf 9 insect cells | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (docked) | ||||||||||||
GRIA3 (RAT) | BDBM50002370![]() ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by PDSP Ki Database | Chirality 13: 523-32 (2001) Article DOI: 10.1002/chir.1172 BindingDB Entry DOI: 10.7270/Q2Z31X6K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA3 (RAT) | BDBM50002370![]() ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Royal Danish School of Pharmacy Curated by PDSP Ki Database | Eur J Pharmacol 189: 381-91 (1990) Article DOI: 10.1016/0922-4106(90)90035-v BindingDB Entry DOI: 10.7270/Q2MW2FNT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM17660![]() ((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned metabotropic glutamate receptor 5 | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
GRM8 (Homo sapiens (Human)) | BDBM50007548![]() ((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 61 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 8 (mGluR-8). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50089894![]() (2-(Amino-carboxy-methyl)-3-[2-(9H-xanthen-9-yl)-et...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Antagonist potency against cloned Metabotropic glutamate receptor 2 | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50089895![]() (2-Amino-3-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarbo...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 3 (mGluR-3). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA3 (RAT) | BDBM2219![]() ((S)-Demethyl-ACPA | Demethyl-ACPA) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by PDSP Ki Database | Chirality 13: 523-32 (2001) Article DOI: 10.1002/chir.1172 BindingDB Entry DOI: 10.7270/Q2Z31X6K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50089895![]() (2-Amino-3-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarbo...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Antagonist potency against cloned Metabotropic glutamate receptor 2 | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50080064![]() (1-[(Z)-2-Cycloheptyloxy-2-(2,6-dichloro-phenyl)-vi...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Antagonist potency against cloned Metabotropic glutamate receptor 2 | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA1 (Homo sapiens (Human)) | BDBM50128264![]() ((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 1 (GluR1) expressed in Sf 9 insect cells | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50089912![]() ((2S)-2-amino-4-methylidenepentanedioic acid | 4-me...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEBI CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned human metabotropic glutamate receptor 1 | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRM8 (Homo sapiens (Human)) | BDBM50062522![]() ((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 8 (mGluR-8). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA1 (Homo sapiens (Human)) | BDBM50017244![]() ((R,S)-2-amino-3-(4-bromo-3-hydroxy-5-isoxazolyl)pr...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 1 (GluR1) expressed in Sf 9 insect cells | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50089894![]() (2-(Amino-carboxy-methyl)-3-[2-(9H-xanthen-9-yl)-et...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 3 (mGluR-3). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50004852![]() (AMAA | Amino-(3-hydroxy-5-methyl-isoxazol-4-yl)-ac...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Royal Danish School of Pharmacy Curated by PDSP Ki Database | Eur J Pharmacol 189: 381-91 (1990) Article DOI: 10.1016/0922-4106(90)90035-v BindingDB Entry DOI: 10.7270/Q2MW2FNT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRM8 (Homo sapiens (Human)) | BDBM50004881![]() ((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 8 (mGluR-8). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50089912![]() ((2S)-2-amino-4-methylidenepentanedioic acid | 4-me...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEBI CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA2 (Homo sapiens (Human)) | BDBM50017244![]() ((R,S)-2-amino-3-(4-bromo-3-hydroxy-5-isoxazolyl)pr...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 2 (GluR2) expressed in Sf 9 insect cells | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA3 (RAT) | BDBM85822![]() (Demethyl-AMPA | OFQ/N | OFQ/N (1-11) | OFQ/N (1-11...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | PC cid PC sid UniChem Similars | Article PubMed | 270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by PDSP Ki Database | Chirality 13: 523-32 (2001) Article DOI: 10.1002/chir.1172 BindingDB Entry DOI: 10.7270/Q2Z31X6K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50084141![]() ((E)-2-methyl-6-styrylpyridine | 2-Methyl-6-((E)-st...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned metabotropic glutamate receptor 5 | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50089906![]() (2-Amino-bicyclo[2.1.1]hexane-2,5-dicarboxylic acid...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50089909![]() (3-[1-Amino-1-carboxy-2-(9H-thioxanthen-9-yl)-ethyl...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned human metabotropic glutamate receptor 1 | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIA2 (Homo sapiens (Human)) | BDBM50128264![]() ((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 2 (GluR2) expressed in Sf 9 insect cells | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM86717![]() (CAS_5218788 | CHEMBL88553 | NSC_5218788 | SIB-1757) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned metabotropic glutamate receptor 5 | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 6 (Homo sapiens (Human)) | BDBM50089890![]() (4-Amino-2-oxa-bicyclo[3.1.0]hexane-4,6-dicarboxyli...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 6 (mGluR-6). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50052398![]() ((2R,4R)-4-aminopyrrolidine-2,4-dicarboxylic acid |...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 3 (mGluR-3). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50034504![]() ((1S,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 3 (mGluR-3). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50052398![]() ((2R,4R)-4-aminopyrrolidine-2,4-dicarboxylic acid |...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEBI CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50002343![]() (2-Methylamino-succinic acid | CHEMBL275325 | NMDA) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Royal Danish School of Pharmacy Curated by PDSP Ki Database | Eur J Pharmacol 189: 381-91 (1990) Article DOI: 10.1016/0922-4106(90)90035-v BindingDB Entry DOI: 10.7270/Q2MW2FNT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50089909![]() (3-[1-Amino-1-carboxy-2-(9H-thioxanthen-9-yl)-ethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned metabotropic glutamate receptor 5 | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50034504![]() ((1S,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 2 agonist | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50089906![]() (2-Amino-bicyclo[2.1.1]hexane-2,5-dicarboxylic acid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 720 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned metabotropic glutamate receptor 5 | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GRIK1 (Homo sapiens (Human)) | BDBM50002370![]() ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 740 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor ionotropic kainate 1 (GluR5) expressed in Sf 9 insect cells | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 6 (Homo sapiens (Human)) | BDBM50007548![]() ((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description Agonist potency against cloned Metabotropic glutamate receptor 6 (mGluR-6). | J Med Chem 43: 2609-45 (2000) Article DOI: 10.1021/jm000007r BindingDB Entry DOI: 10.7270/Q2DZ090Q | |||||||||||
More data for this Ligand-Target Pair |
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