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Compile Data Set for Download or QSAR

Found 717 hits with Last Name = 'mattson' and Initial = 'rj'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM22416
PNG
((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)
Show SMILES Fc1ccc(cc1)[C@@H]1CCNC[C@H]1COc1ccc2OCOc2c1
Show InChI InChI=1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14-,17-/m0/s1
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0.0400n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding inhibition towards human serotonin transporter


J Med Chem 48: 6023-34 (2005)


Article DOI: 10.1021/jm0503291
BindingDB Entry DOI: 10.7270/Q2PN96DN
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Melatonin receptor


(Homo sapiens (Human))
BDBM50136402
PNG
(CHEMBL136531 | N-[(S)-1-(2,3-Dihydro-benzofuran-4-...)
Show SMILES CCCC(=O)N[C@H]1CCN(C1)c1cccc2OCCc12
Show InChI InChI=1S/C16H22N2O2/c1-2-4-16(19)17-12-7-9-18(11-12)14-5-3-6-15-13(14)8-10-20-15/h3,5-6,12H,2,4,7-11H2,1H3,(H,17,19)/t12-/m0/s1
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0.140n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT1 melatonin receptor expressed in NIH3T3 cells.


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50136400
PNG
(CHEMBL343825 | N-[(S)-1-(2,3-Dihydro-benzofuran-4-...)
Show SMILES CCC(=O)N[C@H]1CCN(C1)c1cccc2OCCc12
Show InChI InChI=1S/C15H20N2O2/c1-2-15(18)16-11-6-8-17(10-11)13-4-3-5-14-12(13)7-9-19-14/h3-5,11H,2,6-10H2,1H3,(H,16,18)/t11-/m0/s1
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0.180n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT1 melatonin receptor expressed in NIH3T3 cells.


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM50173715
PNG
((+)3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1...)
Show SMILES CN(C)C[C@H]1C[C@@H]1c1c[nH]c2ccc(cc12)C#N
Show InChI InChI=1S/C15H17N3/c1-18(2)9-11-6-12(11)14-8-17-15-4-3-10(7-16)5-13(14)15/h3-5,8,11-12,17H,6,9H2,1-2H3/t11-,12+/m1/s1
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0.180n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro binding inhibition towards human serotonin transporter


J Med Chem 48: 6023-34 (2005)


Article DOI: 10.1021/jm0503291
BindingDB Entry DOI: 10.7270/Q2PN96DN
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50150431
PNG
((S)-N2-(2-(4-fluorophenoxy)ethyl)-N4-(1-phenylethy...)
Show SMILES C[C@H](Nc1ccnc(NCCOc2ccc(F)cc2)c1)c1ccccc1
Show InChI InChI=1S/C21H22FN3O/c1-16(17-5-3-2-4-6-17)25-19-11-12-23-21(15-19)24-13-14-26-20-9-7-18(22)8-10-20/h2-12,15-16H,13-14H2,1H3,(H2,23,24,25)/t16-/m0/s1
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0.200n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against 5-Hydroxy tryptamine 7 receptor


Bioorg Med Chem Lett 14: 4249-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.007
BindingDB Entry DOI: 10.7270/Q2BV7G34
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM9019
PNG
(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1
Show InChI InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)
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0.300n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT2 melatonin receptor expressed in NIH3T3 cells


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50150430
PNG
(CHEMBL183277 | N*2*-[2-(4-Fluoro-phenoxy)-ethyl]-N...)
Show SMILES C[C@H](Nc1ccnc(NCCOc2ccc(F)cc2)n1)c1ccccc1
Show InChI InChI=1S/C20H21FN4O/c1-15(16-5-3-2-4-6-16)24-19-11-12-22-20(25-19)23-13-14-26-18-9-7-17(21)8-10-18/h2-12,15H,13-14H2,1H3,(H2,22,23,24,25)/t15-/m0/s1
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0.300n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against 5-Hydroxy tryptamine 7 receptor


Bioorg Med Chem Lett 14: 4249-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.007
BindingDB Entry DOI: 10.7270/Q2BV7G34
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50150439
PNG
(CHEMBL182923 | N*2*-Phenethyl-N*4*-((S)-1-phenyl-e...)
Show SMILES C[C@H](Nc1ccnc(NCCc2ccccc2)c1)c1ccccc1
Show InChI InChI=1S/C21H23N3/c1-17(19-10-6-3-7-11-19)24-20-13-15-23-21(16-20)22-14-12-18-8-4-2-5-9-18/h2-11,13,15-17H,12,14H2,1H3,(H2,22,23,24)/t17-/m0/s1
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0.300n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against 5-Hydroxy tryptamine 7 receptor


Bioorg Med Chem Lett 14: 4249-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.007
BindingDB Entry DOI: 10.7270/Q2BV7G34
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50136402
PNG
(CHEMBL136531 | N-[(S)-1-(2,3-Dihydro-benzofuran-4-...)
Show SMILES CCCC(=O)N[C@H]1CCN(C1)c1cccc2OCCc12
Show InChI InChI=1S/C16H22N2O2/c1-2-4-16(19)17-12-7-9-18(11-12)14-5-3-6-15-13(14)8-10-20-15/h3,5-6,12H,2,4,7-11H2,1H3,(H,17,19)/t12-/m0/s1
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0.310n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT2 melatonin receptor expressed in NIH3T3 cells


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50150446
PNG
(CHEMBL181356 | N*2*-(2-Phenoxy-ethyl)-N*4*-((S)-1-...)
Show SMILES C[C@H](Nc1ccnc(NCCOc2ccccc2)c1)c1ccccc1
Show InChI InChI=1S/C21H23N3O/c1-17(18-8-4-2-5-9-18)24-19-12-13-22-21(16-19)23-14-15-25-20-10-6-3-7-11-20/h2-13,16-17H,14-15H2,1H3,(H2,22,23,24)/t17-/m0/s1
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0.400n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against 5-Hydroxy tryptamine 7 receptor


Bioorg Med Chem Lett 14: 4249-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.007
BindingDB Entry DOI: 10.7270/Q2BV7G34
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM9019
PNG
(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Show SMILES COc1ccc2[nH]cc(CCNC(C)=O)c2c1
Show InChI InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)
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0.400n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT1 melatonin receptor expressed in NIH3T3 cells.


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50150428
PNG
(CHEMBL183423 | N*4*-[2-(4-Fluoro-phenoxy)-ethyl]-N...)
Show SMILES C[C@H](Nc1cc(NCCOc2ccc(F)cc2)ccn1)c1ccccc1
Show InChI InChI=1S/C21H22FN3O/c1-16(17-5-3-2-4-6-17)25-21-15-19(11-12-24-21)23-13-14-26-20-9-7-18(22)8-10-20/h2-12,15-16H,13-14H2,1H3,(H2,23,24,25)/t16-/m0/s1
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0.400n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against 5-Hydroxy tryptamine 7 receptor


Bioorg Med Chem Lett 14: 4249-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.007
BindingDB Entry DOI: 10.7270/Q2BV7G34
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50150441
PNG
(CHEMBL181605 | N*2*-[2-(4-Fluoro-phenyl)-ethyl]-N*...)
Show SMILES C[C@H](Nc1ccnc(NCCc2ccc(F)cc2)c1)c1ccccc1
Show InChI InChI=1S/C21H22FN3/c1-16(18-5-3-2-4-6-18)25-20-12-14-24-21(15-20)23-13-11-17-7-9-19(22)10-8-17/h2-10,12,14-16H,11,13H2,1H3,(H2,23,24,25)/t16-/m0/s1
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0.400n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against 5-Hydroxy tryptamine 7 receptor


Bioorg Med Chem Lett 14: 4249-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.007
BindingDB Entry DOI: 10.7270/Q2BV7G34
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50150425
PNG
(CHEMBL184607 | N*4*-(2-Phenoxy-ethyl)-N*2*-((S)-1-...)
Show SMILES C[C@H](Nc1cc(NCCOc2ccccc2)ccn1)c1ccccc1
Show InChI InChI=1S/C21H23N3O/c1-17(18-8-4-2-5-9-18)24-21-16-19(12-13-23-21)22-14-15-25-20-10-6-3-7-11-20/h2-13,16-17H,14-15H2,1H3,(H2,22,23,24)/t17-/m0/s1
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0.400n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against 5-Hydroxy tryptamine 7 receptor


Bioorg Med Chem Lett 14: 4249-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.007
BindingDB Entry DOI: 10.7270/Q2BV7G34
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50136400
PNG
(CHEMBL343825 | N-[(S)-1-(2,3-Dihydro-benzofuran-4-...)
Show SMILES CCC(=O)N[C@H]1CCN(C1)c1cccc2OCCc12
Show InChI InChI=1S/C15H20N2O2/c1-2-15(18)16-11-6-8-17(10-11)13-4-3-5-14-12(13)7-9-19-14/h3-5,11H,2,6-10H2,1H3,(H,16,18)/t11-/m0/s1
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0.400n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT2 melatonin receptor expressed in NIH3T3 cells


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50136409
PNG
(1-[(R)-1-(2,3-Dihydro-benzofuran-4-yl)-pyrrolidin-...)
Show SMILES CCNC(=O)N[C@@H]1CCN(C1)c1cccc2OCCc12
Show InChI InChI=1S/C15H21N3O2/c1-2-16-15(19)17-11-6-8-18(10-11)13-4-3-5-14-12(13)7-9-20-14/h3-5,11H,2,6-10H2,1H3,(H2,16,17,19)/t11-/m1/s1
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0.420n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT2 melatonin receptor expressed in NIH3T3 cells


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM50173715
PNG
((+)3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1...)
Show SMILES CN(C)C[C@H]1C[C@@H]1c1c[nH]c2ccc(cc12)C#N
Show InChI InChI=1S/C15H17N3/c1-18(2)9-11-6-12(11)14-8-17-15-4-3-10(7-16)5-13(14)15/h3-5,8,11-12,17H,6,9H2,1-2H3/t11-,12+/m1/s1
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0.560n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding inhibition towards human serotonin transporter


J Med Chem 48: 6023-34 (2005)


Article DOI: 10.1021/jm0503291
BindingDB Entry DOI: 10.7270/Q2PN96DN
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM50173710
PNG
(3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1H-i...)
Show SMILES CN(C)C[C@H]1C[C@@H]1c1c[nH]c2c(cccc12)C#N
Show InChI InChI=1S/C15H17N3/c1-18(2)9-11-6-13(11)14-8-17-15-10(7-16)4-3-5-12(14)15/h3-5,8,11,13,17H,6,9H2,1-2H3/t11-,13+/m1/s1
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0.580n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding inhibition towards human serotonin transporter


J Med Chem 48: 6023-34 (2005)


Article DOI: 10.1021/jm0503291
BindingDB Entry DOI: 10.7270/Q2PN96DN
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50150422
PNG
(CHEMBL185384 | N*2*-Phenethyl-N*4*-((S)-1-phenyl-e...)
Show SMILES C[C@H](Nc1ccnc(NCCc2ccccc2)n1)c1ccccc1
Show InChI InChI=1S/C20H22N4/c1-16(18-10-6-3-7-11-18)23-19-13-15-22-20(24-19)21-14-12-17-8-4-2-5-9-17/h2-11,13,15-16H,12,14H2,1H3,(H2,21,22,23,24)/t16-/m0/s1
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0.600n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against 5-Hydroxy tryptamine 7 receptor


Bioorg Med Chem Lett 14: 4249-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.007
BindingDB Entry DOI: 10.7270/Q2BV7G34
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50136409
PNG
(1-[(R)-1-(2,3-Dihydro-benzofuran-4-yl)-pyrrolidin-...)
Show SMILES CCNC(=O)N[C@@H]1CCN(C1)c1cccc2OCCc12
Show InChI InChI=1S/C15H21N3O2/c1-2-16-15(19)17-11-6-8-18(10-11)13-4-3-5-14-12(13)7-9-20-14/h3-5,11H,2,6-10H2,1H3,(H2,16,17,19)/t11-/m1/s1
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0.650n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT1 melatonin receptor expressed in NIH3T3 cells.


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM50173717
PNG
(((1S,2S)-2-(5-fluoro-1H-indol-3-yl)cyclopropyl)-N,...)
Show SMILES CN(C)C[C@H]1C[C@@H]1c1c[nH]c2ccc(F)cc12
Show InChI InChI=1S/C14H17FN2/c1-17(2)8-9-5-11(9)13-7-16-14-4-3-10(15)6-12(13)14/h3-4,6-7,9,11,16H,5,8H2,1-2H3/t9-,11+/m1/s1
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0.680n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding inhibition towards human serotonin transporter


J Med Chem 48: 6023-34 (2005)


Article DOI: 10.1021/jm0503291
BindingDB Entry DOI: 10.7270/Q2PN96DN
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM30130
PNG
(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)
Show SMILES CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1
Show InChI InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3
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0.720n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding inhibition towards human serotonin transporter


J Med Chem 48: 6023-34 (2005)


Article DOI: 10.1021/jm0503291
BindingDB Entry DOI: 10.7270/Q2PN96DN
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50136405
PNG
(1-[(S)-1-(2,3-Dihydro-benzofuran-4-yl)-pyrrolidin-...)
Show SMILES CNC(=O)N[C@H]1CCN(C1)c1cccc2OCCc12
Show InChI InChI=1S/C14H19N3O2/c1-15-14(18)16-10-5-7-17(9-10)12-3-2-4-13-11(12)6-8-19-13/h2-4,10H,5-9H2,1H3,(H2,15,16,18)/t10-/m0/s1
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0.900n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT1 melatonin receptor expressed in NIH3T3 cells.


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50136405
PNG
(1-[(S)-1-(2,3-Dihydro-benzofuran-4-yl)-pyrrolidin-...)
Show SMILES CNC(=O)N[C@H]1CCN(C1)c1cccc2OCCc12
Show InChI InChI=1S/C14H19N3O2/c1-15-14(18)16-10-5-7-17(9-10)12-3-2-4-13-11(12)6-8-19-13/h2-4,10H,5-9H2,1H3,(H2,15,16,18)/t10-/m0/s1
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0.940n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT2 melatonin receptor expressed in NIH3T3 cells


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50136398
PNG
(CHEMBL336268 | N-[(S)-1-(2,3-Dihydro-benzofuran-4-...)
Show SMILES CC(=O)N[C@H]1CCN(C1)c1cccc2OCCc12
Show InChI InChI=1S/C14H18N2O2/c1-10(17)15-11-5-7-16(9-11)13-3-2-4-14-12(13)6-8-18-14/h2-4,11H,5-9H2,1H3,(H,15,17)/t11-/m0/s1
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1n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT2 melatonin receptor expressed in NIH3T3 cells


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50150438
PNG
(CHEMBL182071 | N*4*-[2-(4-Fluoro-phenoxy)-ethyl]-N...)
Show SMILES CC(Nc1nccc(NCCOc2ccc(F)cc2)n1)c1ccccc1
Show InChI InChI=1S/C20H21FN4O/c1-15(16-5-3-2-4-6-16)24-20-23-12-11-19(25-20)22-13-14-26-18-9-7-17(21)8-10-18/h2-12,15H,13-14H2,1H3,(H2,22,23,24,25)
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1n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against 5-Hydroxy tryptamine 7 receptor


Bioorg Med Chem Lett 14: 4249-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.007
BindingDB Entry DOI: 10.7270/Q2BV7G34
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50136403
PNG
(CHEMBL139439 | Cyclopropanecarboxylic acid [(S)-1-...)
Show SMILES O=C(N[C@H]1CCN(C1)c1cccc2OCCc12)C1CC1
Show InChI InChI=1S/C16H20N2O2/c19-16(11-4-5-11)17-12-6-8-18(10-12)14-2-1-3-15-13(14)7-9-20-15/h1-3,11-12H,4-10H2,(H,17,19)/t12-/m0/s1
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1.20n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT1 melatonin receptor expressed in NIH3T3 cells.


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50136398
PNG
(CHEMBL336268 | N-[(S)-1-(2,3-Dihydro-benzofuran-4-...)
Show SMILES CC(=O)N[C@H]1CCN(C1)c1cccc2OCCc12
Show InChI InChI=1S/C14H18N2O2/c1-10(17)15-11-5-7-16(9-11)13-3-2-4-14-12(13)6-8-18-14/h2-4,11H,5-9H2,1H3,(H,15,17)/t11-/m0/s1
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1.5n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT1 melatonin receptor expressed in NIH3T3 cells.


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM86192
PNG
(CAS_197801-88-0 | CHEMBL2165203 | SN003)
Show SMILES CCC(COC)n1nnc2c(Nc3ccc(OC)cc3C)nc(C)cc12
Show InChI InChI=1S/C19H25N5O2/c1-6-14(11-25-4)24-17-10-13(3)20-19(18(17)22-23-24)21-16-8-7-15(26-5)9-12(16)2/h7-10,14H,6,11H2,1-5H3,(H,20,21)
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1.70n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Binding affinity to CRFR1 by autoradiography


Bioorg Med Chem Lett 22: 6651-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.08.112
BindingDB Entry DOI: 10.7270/Q20C4WWB
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50152162
PNG
(CHEMBL188844 | CHEMBL2165204 | [3-(6-Dimethylamino...)
Show SMILES CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1ccc(nc1)N(C)C
Show InChI InChI=1S/C21H30N6/c1-7-11-26(12-8-2)19-13-15(3)23-21-20(16(4)24-27(19)21)17-9-10-18(22-14-17)25(5)6/h9-10,13-14H,7-8,11-12H2,1-6H3
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1.70n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Binding affinity to CRFR1 by autoradiography


Bioorg Med Chem Lett 22: 6651-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.08.112
BindingDB Entry DOI: 10.7270/Q20C4WWB
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50395823
PNG
(CHEMBL2165205)
Show SMILES COCCN(CCOC)Cc1cc(C)nc2c(c(C)nn12)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C21H26Cl2N4O2/c1-14-11-17(13-26(7-9-28-3)8-10-29-4)27-21(24-14)20(15(2)25-27)18-6-5-16(22)12-19(18)23/h5-6,11-12H,7-10,13H2,1-4H3
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1.70n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Binding affinity to CRFR1 by autoradiography


Bioorg Med Chem Lett 22: 6651-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.08.112
BindingDB Entry DOI: 10.7270/Q20C4WWB
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM50173712
PNG
(3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1-et...)
Show SMILES CCn1cc([C@H]2C[C@@H]2CN(C)C)c2cc(ccc12)C#N
Show InChI InChI=1S/C17H21N3/c1-4-20-11-16(14-8-13(14)10-19(2)3)15-7-12(9-18)5-6-17(15)20/h5-7,11,13-14H,4,8,10H2,1-3H3/t13-,14+/m1/s1
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1.80n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding inhibition towards human serotonin transporter


J Med Chem 48: 6023-34 (2005)


Article DOI: 10.1021/jm0503291
BindingDB Entry DOI: 10.7270/Q2PN96DN
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50395822
PNG
(CHEMBL1762817)
Show SMILES COCCN(CCOC)c1nc(C)nc2c(c(C)nn12)-c1ccc(Br)cc1Cl
Show InChI InChI=1S/C19H23BrClN5O2/c1-12-17(15-6-5-14(20)11-16(15)21)18-22-13(2)23-19(26(18)24-12)25(7-9-27-3)8-10-28-4/h5-6,11H,7-10H2,1-4H3
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2n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Binding affinity to CRFR1 by autoradiography


Bioorg Med Chem Lett 22: 6651-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.08.112
BindingDB Entry DOI: 10.7270/Q20C4WWB
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM50162700
PNG
(3-(3-(dimethylamino)propyl)-1H-indole-5-carbonitri...)
Show SMILES CN(C)CCCc1c[nH]c2ccc(cc12)C#N
Show InChI InChI=1S/C14H17N3/c1-17(2)7-3-4-12-10-16-14-6-5-11(9-15)8-13(12)14/h5-6,8,10,16H,3-4,7H2,1-2H3
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2n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding inhibition towards human serotonin transporter


J Med Chem 48: 6023-34 (2005)


Article DOI: 10.1021/jm0503291
BindingDB Entry DOI: 10.7270/Q2PN96DN
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50150408
PNG
(CHEMBL182937 | N-[2-(4-Fluoro-phenoxy)-ethyl]-N''-...)
Show SMILES C[C@H](Nc1nc(N)nc(NCCOc2ccc(F)cc2)n1)c1ccc(F)cc1
Show InChI InChI=1S/C19H20F2N6O/c1-12(13-2-4-14(20)5-3-13)24-19-26-17(22)25-18(27-19)23-10-11-28-16-8-6-15(21)7-9-16/h2-9,12H,10-11H2,1H3,(H4,22,23,24,25,26,27)/t12-/m0/s1
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2n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against 5-Hydroxy tryptamine 7 receptor


Bioorg Med Chem Lett 14: 4245-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.008
BindingDB Entry DOI: 10.7270/Q2GM86RJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50150413
PNG
(CHEMBL413049 | N-[2-(4-Fluoro-phenyl)-ethyl]-N''-[...)
Show SMILES C[C@H](Nc1nc(N)nc(NCCc2ccc(F)cc2)n1)c1ccc(F)cc1
Show InChI InChI=1S/C19H20F2N6/c1-12(14-4-8-16(21)9-5-14)24-19-26-17(22)25-18(27-19)23-11-10-13-2-6-15(20)7-3-13/h2-9,12H,10-11H2,1H3,(H4,22,23,24,25,26,27)/t12-/m0/s1
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2n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against 5-Hydroxy tryptamine 7 receptor


Bioorg Med Chem Lett 14: 4245-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.008
BindingDB Entry DOI: 10.7270/Q2GM86RJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50150407
PNG
(CHEMBL180086 | N-[1-(4-Fluoro-phenyl)-ethyl]-N''-(...)
Show SMILES CC(Nc1nc(N)nc(NCCc2cccs2)n1)c1ccc(F)cc1
Show InChI InChI=1S/C17H19FN6S/c1-11(12-4-6-13(18)7-5-12)21-17-23-15(19)22-16(24-17)20-9-8-14-3-2-10-25-14/h2-7,10-11H,8-9H2,1H3,(H4,19,20,21,22,23,24)
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2n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against 5-Hydroxy tryptamine 7 receptor


Bioorg Med Chem Lett 14: 4245-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.008
BindingDB Entry DOI: 10.7270/Q2GM86RJ
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50395822
PNG
(CHEMBL1762817)
Show SMILES COCCN(CCOC)c1nc(C)nc2c(c(C)nn12)-c1ccc(Br)cc1Cl
Show InChI InChI=1S/C19H23BrClN5O2/c1-12-17(15-6-5-14(20)11-16(15)21)18-22-13(2)23-19(26(18)24-12)25(7-9-27-3)8-10-28-4/h5-6,11H,7-10H2,1-4H3
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2n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Binding affinity to CRF1 receptor (unknown origin)


Bioorg Med Chem Lett 23: 2052-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.009
BindingDB Entry DOI: 10.7270/Q2DR2WW3
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50150433
PNG
(CHEMBL185511 | N*2*-(2-Phenoxy-ethyl)-N*4*-((S)-1-...)
Show SMILES C[C@H](Nc1ccnc(NCCOc2ccccc2)n1)c1ccccc1
Show InChI InChI=1S/C20H22N4O/c1-16(17-8-4-2-5-9-17)23-19-12-13-21-20(24-19)22-14-15-25-18-10-6-3-7-11-18/h2-13,16H,14-15H2,1H3,(H2,21,22,23,24)/t16-/m0/s1
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2n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against 5-Hydroxy tryptamine 7 receptor


Bioorg Med Chem Lett 14: 4249-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.007
BindingDB Entry DOI: 10.7270/Q2BV7G34
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM50173717
PNG
(((1S,2S)-2-(5-fluoro-1H-indol-3-yl)cyclopropyl)-N,...)
Show SMILES CN(C)C[C@H]1C[C@@H]1c1c[nH]c2ccc(F)cc12
Show InChI InChI=1S/C14H17FN2/c1-17(2)8-9-5-11(9)13-7-16-14-4-3-10(15)6-12(13)14/h3-4,6-7,9,11,16H,5,8H2,1-2H3/t9-,11+/m1/s1
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2.10n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding inhibition towards human serotonin transporter


J Med Chem 48: 6023-34 (2005)


Article DOI: 10.1021/jm0503291
BindingDB Entry DOI: 10.7270/Q2PN96DN
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50136401
PNG
(1-[(S)-1-(2,3-Dihydro-benzofuran-4-yl)-pyrrolidin-...)
Show SMILES CCNC(=O)N[C@H]1CCN(C1)c1cccc2OCCc12
Show InChI InChI=1S/C15H21N3O2/c1-2-16-15(19)17-11-6-8-18(10-11)13-4-3-5-14-12(13)7-9-20-14/h3-5,11H,2,6-10H2,1H3,(H2,16,17,19)/t11-/m0/s1
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2.10n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT2 melatonin receptor expressed in NIH3T3 cells


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50136397
PNG
(1-[(R)-1-(2,3-Dihydro-benzofuran-4-yl)-pyrrolidin-...)
Show SMILES CNC(=O)N[C@@H]1CCN(C1)c1cccc2OCCc12
Show InChI InChI=1S/C14H19N3O2/c1-15-14(18)16-10-5-7-17(9-10)12-3-2-4-13-11(12)6-8-19-13/h2-4,10H,5-9H2,1H3,(H2,15,16,18)/t10-/m1/s1
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2.20n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT1 melatonin receptor expressed in NIH3T3 cells.


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50136412
PNG
(1-[(R)-1-(2,3-Dihydro-benzofuran-4-yl)-pyrrolidin-...)
Show SMILES CCCNC(=O)N[C@@H]1CCN(C1)c1cccc2OCCc12
Show InChI InChI=1S/C16H23N3O2/c1-2-8-17-16(20)18-12-6-9-19(11-12)14-4-3-5-15-13(14)7-10-21-15/h3-5,12H,2,6-11H2,1H3,(H2,17,18,20)/t12-/m1/s1
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2.60n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT2 melatonin receptor expressed in NIH3T3 cells


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50136407
PNG
(CHEMBL139497 | N-[(S)-1-(3-Methoxy-phenyl)-pyrroli...)
Show SMILES CCCC(=O)N[C@H]1CCN(C1)c1cccc(OC)c1
Show InChI InChI=1S/C15H22N2O2/c1-3-5-15(18)16-12-8-9-17(11-12)13-6-4-7-14(10-13)19-2/h4,6-7,10,12H,3,5,8-9,11H2,1-2H3,(H,16,18)/t12-/m0/s1
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2.60n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT2 melatonin receptor expressed in NIH3T3 cells


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50136403
PNG
(CHEMBL139439 | Cyclopropanecarboxylic acid [(S)-1-...)
Show SMILES O=C(N[C@H]1CCN(C1)c1cccc2OCCc12)C1CC1
Show InChI InChI=1S/C16H20N2O2/c19-16(11-4-5-11)17-12-6-8-18(10-12)14-2-1-3-15-13(14)7-9-20-15/h1-3,11-12H,4-10H2,(H,17,19)/t12-/m0/s1
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2.80n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT2 melatonin receptor expressed in NIH3T3 cells


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50150410
PNG
(CHEMBL182174 | N-(2-Phenoxy-ethyl)-N''-((S)-1-phen...)
Show SMILES C[C@H](Nc1nc(N)nc(NCCOc2ccccc2)n1)c1ccccc1
Show InChI InChI=1S/C19H22N6O/c1-14(15-8-4-2-5-9-15)22-19-24-17(20)23-18(25-19)21-12-13-26-16-10-6-3-7-11-16/h2-11,14H,12-13H2,1H3,(H4,20,21,22,23,24,25)/t14-/m0/s1
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3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against 5-Hydroxy tryptamine 7 receptor


Bioorg Med Chem Lett 14: 4245-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.008
BindingDB Entry DOI: 10.7270/Q2GM86RJ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50150436
PNG
(CHEMBL181950 | N*4*-Phenethyl-N*2*-((S)-1-phenyl-e...)
Show SMILES C[C@H](Nc1cc(NCCc2ccccc2)ccn1)c1ccccc1
Show InChI InChI=1S/C21H23N3/c1-17(19-10-6-3-7-11-19)24-21-16-20(13-15-23-21)22-14-12-18-8-4-2-5-9-18/h2-11,13,15-17H,12,14H2,1H3,(H2,22,23,24)/t17-/m0/s1
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3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against 5-Hydroxy tryptamine 7 receptor


Bioorg Med Chem Lett 14: 4249-52 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.007
BindingDB Entry DOI: 10.7270/Q2BV7G34
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50150412
PNG
(CHEMBL183862 | N-(2-Phenoxy-ethyl)-N''-((S)-1-phen...)
Show SMILES C[C@H](Nc1ncnc(NCCOc2ccccc2)n1)c1ccccc1
Show InChI InChI=1S/C19H21N5O/c1-15(16-8-4-2-5-9-16)23-19-22-14-21-18(24-19)20-12-13-25-17-10-6-3-7-11-17/h2-11,14-15H,12-13H2,1H3,(H2,20,21,22,23,24)/t15-/m0/s1
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3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against 5-Hydroxy tryptamine 7 receptor


Bioorg Med Chem Lett 14: 4245-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.008
BindingDB Entry DOI: 10.7270/Q2GM86RJ
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50136407
PNG
(CHEMBL139497 | N-[(S)-1-(3-Methoxy-phenyl)-pyrroli...)
Show SMILES CCCC(=O)N[C@H]1CCN(C1)c1cccc(OC)c1
Show InChI InChI=1S/C15H22N2O2/c1-3-5-15(18)16-12-8-9-17(11-12)13-6-4-7-14(10-13)19-2/h4,6-7,10,12H,3,5,8-9,11H2,1-2H3,(H,16,18)/t12-/m0/s1
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3.70n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT1 melatonin receptor expressed in NIH3T3 cells.


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50136394
PNG
(CHEMBL138228 | Cyclopropanecarboxylic acid [(R)-1-...)
Show SMILES O=C(N[C@@H]1CCN(C1)c1cccc2OCCc12)C1CC1
Show InChI InChI=1S/C16H20N2O2/c19-16(11-4-5-11)17-12-6-8-18(10-12)14-2-1-3-15-13(14)7-9-20-15/h1-3,11-12H,4-10H2,(H,17,19)/t12-/m1/s1
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3.90n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against human MT1 melatonin receptor expressed in NIH3T3 cells.


Bioorg Med Chem Lett 13: 4381-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.030
BindingDB Entry DOI: 10.7270/Q2X066FK
More data for this
Ligand-Target Pair
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