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Compile Data Set for Download or QSAR

Found 96 hits with Last Name = 'otterness' and Initial = 'ig'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase-12 (MMP12)


(Homo sapiens (Human))
BDBM50148216
PNG
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C18H19FN2O6S/c19-13-1-3-14(4-2-13)27-15-5-7-16(8-6-15)28(24,25)21-18(17(22)20-23)9-11-26-12-10-18/h1-8,21,23H,9-12H2,(H,20,22)
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n/an/a 0.240n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloprotease-12


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM50148208
PNG
(3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-8-ox...)
Show SMILES ONC(=O)C1(CC2CCC(C1)O2)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C20H21FN2O6S/c21-13-1-3-14(4-2-13)28-15-7-9-18(10-8-15)30(26,27)23-20(19(24)22-25)11-16-5-6-17(12-20)29-16/h1-4,7-10,16-17,23,25H,5-6,11-12H2,(H,22,24)
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n/an/a 0.260n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloprotease-2


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50451954
PNG
(CHEMBL2111753)
Show SMILES ONC(=O)[C@]1(CCCOC1)NS(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1
Show InChI InChI=1/C18H19ClN2O6S/c19-13-2-4-14(5-3-13)27-15-6-8-16(9-7-15)28(24,25)21-18(17(22)20-23)10-1-11-26-12-18/h2-9,21,23H,1,10-12H2,(H,20,22)/t18-/s2
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n/an/a 0.350n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148214
PNG
((R)-3-[4-(4-Chloro-phenoxy)-benzenesulfonylamino]-...)
Show SMILES ONC(=O)[C@]1(CCOC1)NS(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C17H17ClN2O6S/c18-12-1-3-13(4-2-12)26-14-5-7-15(8-6-14)27(23,24)20-17(16(21)19-22)9-10-25-11-17/h1-8,20,22H,9-11H2,(H,19,21)/t17-/m1/s1
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n/an/a 0.370n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Matrix Metalloproteinase-8 (MMP-8)


(Homo sapiens (Human))
BDBM50148208
PNG
(3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-8-ox...)
Show SMILES ONC(=O)C1(CC2CCC(C1)O2)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C20H21FN2O6S/c21-13-1-3-14(4-2-13)28-15-7-9-18(10-8-15)30(26,27)23-20(19(24)22-25)11-16-5-6-17(12-20)29-16/h1-4,7-10,16-17,23,25H,5-6,11-12H2,(H,22,24)
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n/an/a 0.400n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloprotease-8


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148208
PNG
(3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-8-ox...)
Show SMILES ONC(=O)C1(CC2CCC(C1)O2)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C20H21FN2O6S/c21-13-1-3-14(4-2-13)28-15-7-9-18(10-8-15)30(26,27)23-20(19(24)22-25)11-16-5-6-17(12-20)29-16/h1-4,7-10,16-17,23,25H,5-6,11-12H2,(H,22,24)
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n/an/a 0.5n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148228
PNG
(1-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-cycl...)
Show SMILES ONC(=O)C1(CCC1)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C17H17FN2O5S/c18-12-2-4-13(5-3-12)25-14-6-8-15(9-7-14)26(23,24)20-17(10-1-11-17)16(21)19-22/h2-9,20,22H,1,10-11H2,(H,19,21)
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n/an/a 0.530n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148198
PNG
(4-[4-(3-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2cccc(F)c2)cc1
Show InChI InChI=1S/C18H19FN2O6S/c19-13-2-1-3-15(12-13)27-14-4-6-16(7-5-14)28(24,25)21-18(17(22)20-23)8-10-26-11-9-18/h1-7,12,21,23H,8-11H2,(H,20,22)
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n/an/a 0.560n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148204
PNG
(3-[4-(4-Chloro-phenoxy)-benzenesulfonylamino]-8-ox...)
Show SMILES ONC(=O)C1(CC2CCC(C1)O2)NS(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C20H21ClN2O6S/c21-13-1-3-14(4-2-13)28-15-7-9-18(10-8-15)30(26,27)23-20(19(24)22-25)11-16-5-6-17(12-20)29-16/h1-4,7-10,16-17,23,25H,5-6,11-12H2,(H,22,24)
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n/an/a 0.650n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148232
PNG
(4-[4-(2-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2ccccc2F)cc1
Show InChI InChI=1S/C18H19FN2O6S/c19-15-3-1-2-4-16(15)27-13-5-7-14(8-6-13)28(24,25)21-18(17(22)20-23)9-11-26-12-10-18/h1-8,21,23H,9-12H2,(H,20,22)
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n/an/a 0.650n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148216
PNG
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C18H19FN2O6S/c19-13-1-3-14(4-2-13)27-15-5-7-16(8-6-15)28(24,25)21-18(17(22)20-23)9-11-26-12-10-18/h1-8,21,23H,9-12H2,(H,20,22)
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n/an/a 0.75n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148223
PNG
((R)-3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-...)
Show SMILES ONC(=O)[C@]1(CCOC1)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C17H17FN2O6S/c18-12-1-3-13(4-2-12)26-14-5-7-15(8-6-14)27(23,24)20-17(16(21)19-22)9-10-25-11-17/h1-8,20,22H,9-11H2,(H,19,21)/t17-/m1/s1
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n/an/a 0.770n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148212
PNG
(4-[4-(4-Methoxy-phenoxy)-benzenesulfonylamino]-tet...)
Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)NC2(CCOCC2)C(=O)NO)cc1
Show InChI InChI=1S/C19H22N2O7S/c1-26-14-2-4-15(5-3-14)28-16-6-8-17(9-7-16)29(24,25)21-19(18(22)20-23)10-12-27-13-11-19/h2-9,21,23H,10-13H2,1H3,(H,20,22)
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n/an/a 0.870n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148231
PNG
(2-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-N-hy...)
Show SMILES CC(C)(NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1)C(=O)NO
Show InChI InChI=1S/C16H17FN2O5S/c1-16(2,15(20)18-21)19-25(22,23)14-9-7-13(8-10-14)24-12-5-3-11(17)4-6-12/h3-10,19,21H,1-2H3,(H,18,20)
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n/an/a 0.900n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148201
PNG
(1-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-cycl...)
Show SMILES ONC(=O)C1(CCCC1)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C18H19FN2O5S/c19-13-3-5-14(6-4-13)26-15-7-9-16(10-8-15)27(24,25)21-18(17(22)20-23)11-1-2-12-18/h3-10,21,23H,1-2,11-12H2,(H,20,22)
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n/an/a 0.900n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148197
PNG
(1-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-cycl...)
Show SMILES ONC(=O)C1(CC1)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C16H15FN2O5S/c17-11-1-3-12(4-2-11)24-13-5-7-14(8-6-13)25(22,23)19-16(9-10-16)15(20)18-21/h1-8,19,21H,9-10H2,(H,18,20)
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n/an/a 0.930n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148222
PNG
((S)-3-[4-(4-Chloro-phenoxy)-benzenesulfonylamino]-...)
Show SMILES ONC(=O)[C@@]1(CCOC1)NS(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C17H17ClN2O6S/c18-12-1-3-13(4-2-12)26-14-5-7-15(8-6-14)27(23,24)20-17(16(21)19-22)9-10-25-11-17/h1-8,20,22H,9-11H2,(H,19,21)/t17-/m0/s1
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n/an/a 0.930n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148226
PNG
(1-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-cycl...)
Show SMILES ONC(=O)C1(CCCCC1)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C19H21FN2O5S/c20-14-4-6-15(7-5-14)27-16-8-10-17(11-9-16)28(25,26)22-19(18(23)21-24)12-2-1-3-13-19/h4-11,22,24H,1-3,12-13H2,(H,21,23)
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n/an/a 0.970n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50451953
PNG
(CHEMBL2111754)
Show SMILES ONC(=O)[C@]1(CCCOC1)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1/C18H19FN2O6S/c19-13-2-4-14(5-3-13)27-15-6-8-16(9-7-15)28(24,25)21-18(17(22)20-23)10-1-11-26-12-18/h2-9,21,23H,1,10-12H2,(H,20,22)/t18-/s2
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n/an/a 1.20n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148224
PNG
(4-[4-(4-Chloro-phenoxy)-benzenesulfonylamino]-tetr...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C18H19ClN2O6S/c19-13-1-3-14(4-2-13)27-15-5-7-16(8-6-15)28(24,25)21-18(17(22)20-23)9-11-26-12-10-18/h1-8,21,23H,9-12H2,(H,20,22)
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n/an/a 1.20n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148227
PNG
((S)-3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-...)
Show SMILES ONC(=O)[C@@]1(CCOC1)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C17H17FN2O6S/c18-12-1-3-13(4-2-12)26-14-5-7-15(8-6-14)27(23,24)20-17(16(21)19-22)9-10-25-11-17/h1-8,20,22H,9-11H2,(H,19,21)/t17-/m0/s1
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n/an/a 1.30n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Matrix Metalloproteinase-8 (MMP-8)


(Homo sapiens (Human))
BDBM50148216
PNG
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C18H19FN2O6S/c19-13-1-3-14(4-2-13)27-15-5-7-16(8-6-15)28(24,25)21-18(17(22)20-23)9-11-26-12-10-18/h1-8,21,23H,9-12H2,(H,20,22)
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n/an/a 1.40n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloprotease-8


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM50148208
PNG
(3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-8-ox...)
Show SMILES ONC(=O)C1(CC2CCC(C1)O2)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C20H21FN2O6S/c21-13-1-3-14(4-2-13)28-15-7-9-18(10-8-15)30(26,27)23-20(19(24)22-25)11-16-5-6-17(12-20)29-16/h1-4,7-10,16-17,23,25H,5-6,11-12H2,(H,22,24)
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n/an/a 1.40n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloprotease-9


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148211
PNG
(4-[4-(4-Chloro-pyridin-2-yloxy)-benzenesulfonylami...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2cc(Cl)ccn2)cc1
Show InChI InChI=1S/C17H18ClN3O6S/c18-12-5-8-19-15(11-12)27-13-1-3-14(4-2-13)28(24,25)21-17(16(22)20-23)6-9-26-10-7-17/h1-5,8,11,21,23H,6-7,9-10H2,(H,20,22)
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n/an/a 1.5n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148210
PNG
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Show SMILES ONC(=O)C1(CCSCC1)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C18H19FN2O5S2/c19-13-1-3-14(4-2-13)26-15-5-7-16(8-6-15)28(24,25)21-18(17(22)20-23)9-11-27-12-10-18/h1-8,21,23H,9-12H2,(H,20,22)
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n/an/a 1.5n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148217
PNG
(4-(4-Phenoxy-benzenesulfonylamino)-tetrahydro-pyra...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C18H20N2O6S/c21-17(19-22)18(10-12-25-13-11-18)20-27(23,24)16-8-6-15(7-9-16)26-14-4-2-1-3-5-14/h1-9,20,22H,10-13H2,(H,19,21)
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n/an/a 1.5n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM50148216
PNG
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C18H19FN2O6S/c19-13-1-3-14(4-2-13)27-15-5-7-16(8-6-15)28(24,25)21-18(17(22)20-23)9-11-26-12-10-18/h1-8,21,23H,9-12H2,(H,20,22)
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n/an/a 1.60n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloprotease-2


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM8466
PNG
((2R)-N-hydroxy-2-[(4-methoxybenzene)sulfonamido]-3...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N[C@H](C(C)C)C(=O)NO
Show InChI InChI=1/C12H18N2O5S/c1-8(2)11(12(15)13-16)14-20(17,18)10-6-4-9(19-3)5-7-10/h4-8,11,14,16H,1-3H3,(H,13,15)/t11-/s2
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n/an/a 1.70n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148220
PNG
(4-[4-(4-Cyano-phenoxy)-benzenesulfonylamino]-tetra...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2ccc(cc2)C#N)cc1
Show InChI InChI=1S/C19H19N3O6S/c20-13-14-1-3-15(4-2-14)28-16-5-7-17(8-6-16)29(25,26)22-19(18(23)21-24)9-11-27-12-10-19/h1-8,22,24H,9-12H2,(H,21,23)
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n/an/a 1.70n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148213
PNG
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-1,1-...)
Show SMILES ONC(=O)C1(CCS(=O)(=O)CC1)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C18H19FN2O7S2/c19-13-1-3-14(4-2-13)28-15-5-7-16(8-6-15)30(26,27)21-18(17(22)20-23)9-11-29(24,25)12-10-18/h1-8,21,23H,9-12H2,(H,20,22)
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n/an/a 2n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM8465
PNG
((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO
Show InChI InChI=1/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/s2
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n/an/a 2.5n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against human matrix metalloprotease-1 (MMP-1)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Collagenase 3


(Homo sapiens (Human))
BDBM50148208
PNG
(3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-8-ox...)
Show SMILES ONC(=O)C1(CC2CCC(C1)O2)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C20H21FN2O6S/c21-13-1-3-14(4-2-13)28-15-7-9-18(10-8-15)30(26,27)23-20(19(24)22-25)11-16-5-6-17(12-20)29-16/h1-4,7-10,16-17,23,25H,5-6,11-12H2,(H,22,24)
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n/an/a 3.30n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Stromelysin-1


(Homo sapiens (Human))
BDBM50148208
PNG
(3-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-8-ox...)
Show SMILES ONC(=O)C1(CC2CCC(C1)O2)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C20H21FN2O6S/c21-13-1-3-14(4-2-13)28-15-7-9-18(10-8-15)30(26,27)23-20(19(24)22-25)11-16-5-6-17(12-20)29-16/h1-4,7-10,16-17,23,25H,5-6,11-12H2,(H,22,24)
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n/an/a 4.20n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloprotease-3


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148196
PNG
(4-(4'-Fluoro-biphenyl-4-sulfonylamino)-tetrahydro-...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(cc1)-c1ccc(F)cc1
Show InChI InChI=1S/C18H19FN2O5S/c19-15-5-1-13(2-6-15)14-3-7-16(8-4-14)27(24,25)21-18(17(22)20-23)9-11-26-12-10-18/h1-8,21,23H,9-12H2,(H,20,22)
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n/an/a 4.40n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148221
PNG
(4-[4-(4-Fluoro-phenylsulfanyl)-benzenesulfonylamin...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Sc2ccc(F)cc2)cc1
Show InChI InChI=1S/C18H19FN2O5S2/c19-13-1-3-14(4-2-13)27-15-5-7-16(8-6-15)28(24,25)21-18(17(22)20-23)9-11-26-12-10-18/h1-8,21,23H,9-12H2,(H,20,22)
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n/an/a 4.60n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148202
PNG
(4-[4-(3-Chloro-phenoxy)-benzenesulfonylamino]-tetr...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2cccc(Cl)c2)cc1
Show InChI InChI=1S/C18H19ClN2O6S/c19-13-2-1-3-15(12-13)27-14-4-6-16(7-5-14)28(24,25)21-18(17(22)20-23)8-10-26-11-9-18/h1-7,12,21,23H,8-11H2,(H,20,22)
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n/an/a 4.60n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148206
PNG
(4-[4-(Naphthalen-2-yloxy)-benzenesulfonylamino]-te...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C22H22N2O6S/c25-21(23-26)22(11-13-29-14-12-22)24-31(27,28)20-9-7-18(8-10-20)30-19-6-5-16-3-1-2-4-17(16)15-19/h1-10,15,24,26H,11-14H2,(H,23,25)
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n/an/a 5n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148205
PNG
(4-[4-(Pyridin-4-yloxy)-benzenesulfonylamino]-tetra...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2ccncc2)cc1
Show InChI InChI=1S/C17H19N3O6S/c21-16(19-22)17(7-11-25-12-8-17)20-27(23,24)15-3-1-13(2-4-15)26-14-5-9-18-10-6-14/h1-6,9-10,20,22H,7-8,11-12H2,(H,19,21)
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n/an/a 5.70n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148203
PNG
(4-(4-Benzyloxy-benzenesulfonylamino)-tetrahydro-py...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C19H22N2O6S/c22-18(20-23)19(10-12-26-13-11-19)21-28(24,25)17-8-6-16(7-9-17)27-14-15-4-2-1-3-5-15/h1-9,21,23H,10-14H2,(H,20,22)
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n/an/a 6.5n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Matrix metalloproteinase-14 (MMP14)


(Homo sapiens (Human))
BDBM50148216
PNG
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C18H19FN2O6S/c19-13-1-3-14(4-2-13)27-15-5-7-16(8-6-15)28(24,25)21-18(17(22)20-23)9-11-26-12-10-18/h1-8,21,23H,9-12H2,(H,20,22)
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n/an/a 7.40n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloprotease-14


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148209
PNG
(4-[4-(2-Chloro-phenoxy)-benzenesulfonylamino]-tetr...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2ccccc2Cl)cc1
Show InChI InChI=1S/C18H19ClN2O6S/c19-15-3-1-2-4-16(15)27-13-5-7-14(8-6-13)28(24,25)21-18(17(22)20-23)9-11-26-12-10-18/h1-8,21,23H,9-12H2,(H,20,22)
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n/an/a 9.70n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148233
PNG
(4-[4-(4-Fluoro-benzyloxy)-benzenesulfonylamino]-te...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(OCc2ccc(F)cc2)cc1
Show InChI InChI=1S/C19H21FN2O6S/c20-15-3-1-14(2-4-15)13-28-16-5-7-17(8-6-16)29(25,26)22-19(18(23)21-24)9-11-27-12-10-19/h1-8,22,24H,9-13H2,(H,21,23)
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n/an/a 11n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM50148216
PNG
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C18H19FN2O6S/c19-13-1-3-14(4-2-13)27-15-5-7-16(8-6-15)28(24,25)21-18(17(22)20-23)9-11-26-12-10-18/h1-8,21,23H,9-12H2,(H,20,22)
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n/an/a 12n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloprotease-9


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148230
PNG
(4-[4-(Pyridin-2-yloxy)-benzenesulfonylamino]-tetra...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2ccccn2)cc1
Show InChI InChI=1S/C17H19N3O6S/c21-16(19-22)17(8-11-25-12-9-17)20-27(23,24)14-6-4-13(5-7-14)26-15-3-1-2-10-18-15/h1-7,10,20,22H,8-9,11-12H2,(H,19,21)
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n/an/a 13n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148215
PNG
(4-[4-(4-Fluoro-pyridin-2-yloxy)-benzenesulfonylami...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2cc(F)ccn2)cc1
Show InChI InChI=1S/C17H18FN3O6S/c18-12-5-8-19-15(11-12)27-13-1-3-14(4-2-13)28(24,25)21-17(16(22)20-23)6-9-26-10-7-17/h1-5,8,11,21,23H,6-7,9-10H2,(H,20,22)
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n/an/a 14n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Stromelysin-1


(Homo sapiens (Human))
BDBM50148216
PNG
(4-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-tetr...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1
Show InChI InChI=1S/C18H19FN2O6S/c19-13-1-3-14(4-2-13)27-15-5-7-16(8-6-15)28(24,25)21-18(17(22)20-23)9-11-26-12-10-18/h1-8,21,23H,9-12H2,(H,20,22)
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n/an/a 16n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of matrix metalloprotease-3


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148200
PNG
(CHEMBL114378 | N-Hydroxy-2-(4-methoxy-benzenesulfo...)
Show SMILES COc1ccc(cc1)S(=O)(=O)NC(C)(C)C(=O)NO
Show InChI InChI=1S/C11H16N2O5S/c1-11(2,10(14)12-15)13-19(16,17)9-6-4-8(18-3)5-7-9/h4-7,13,15H,1-3H3,(H,12,14)
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n/an/a 17n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM8465
PNG
((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO
Show InChI InChI=1/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/s2
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n/an/a 18n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148229
PNG
(4-[4-(2-Fluoro-benzyloxy)-benzenesulfonylamino]-te...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(OCc2ccccc2F)cc1
Show InChI InChI=1S/C19H21FN2O6S/c20-17-4-2-1-3-14(17)13-28-15-5-7-16(8-6-15)29(25,26)22-19(18(23)21-24)9-11-27-12-10-19/h1-8,22,24H,9-13H2,(H,21,23)
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n/an/a 19n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
Collagenase 3


(Homo sapiens (Human))
BDBM50148218
PNG
(4-[4-(3-Fluoro-benzyloxy)-benzenesulfonylamino]-te...)
Show SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(OCc2cccc(F)c2)cc1
Show InChI InChI=1S/C19H21FN2O6S/c20-15-3-1-2-14(12-15)13-28-16-4-6-17(7-5-16)29(25,26)22-19(18(23)21-24)8-10-27-11-9-19/h1-7,12,22,24H,8-11,13H2,(H,21,23)
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n/an/a 24n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against matrix metalloprotease-13 (MMP-13)


Bioorg Med Chem Lett 14: 3389-95 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.083
BindingDB Entry DOI: 10.7270/Q25Q4WPN
More data for this
Ligand-Target Pair
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