BindingDB PrimarySearch

Found 1028 hits with Last Name = 'pickering' and Initial = 'ds'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
GRIA3 (RAT)	BDBM50166288 ((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	0.00220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR3 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 4 (Rattus norvegicus)	BDBM50166288 ((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL MMDB PC cid PC sid UniChem Similars	MMDB Article PubMed	0.00270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR4 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 2 (Rattus norvegicus)	BDBM50166288 ((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL MMDB PC cid PC sid UniChem Similars	MMDB Article PubMed	0.00390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR2 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (GluA1) (Rattus norvegicus (Rat))	BDBM50166288 ((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	0.00520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR1 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 2 (Rattus norvegicus)	BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) Show SMILES Cc1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR2 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
GRIA3 (RAT)	BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) Show SMILES Cc1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR3 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (GluA1) (Rattus norvegicus (Rat))	BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) Show SMILES Cc1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR1 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 4 (Rattus norvegicus)	BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) Show SMILES Cc1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR4 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 4 (Rattus norvegicus)	BDBM50166286 ((RS)-2-amino-3-[3-hydroxy-5-(2-ethyl-2H-5-tetrazol...) Show SMILES CCn1nnc(n1)-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR4 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
GRIA3 (RAT)	BDBM50166286 ((RS)-2-amino-3-[3-hydroxy-5-(2-ethyl-2H-5-tetrazol...) Show SMILES CCn1nnc(n1)-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR3 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 2 (Rattus norvegicus)	BDBM50166286 ((RS)-2-amino-3-[3-hydroxy-5-(2-ethyl-2H-5-tetrazol...) Show SMILES CCn1nnc(n1)-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR2 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate kainate (RAT)	BDBM50166288 ((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	0.0810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]SYM 2081 from rat recombinant GluR5 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (GluA1) (Rattus norvegicus (Rat))	BDBM50166286 ((RS)-2-amino-3-[3-hydroxy-5-(2-ethyl-2H-5-tetrazol...) Show SMILES CCn1nnc(n1)-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR1 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 4 (Rattus norvegicus)	BDBM50211399 ((RS)-2-amino-3-[3-hydroxy-5-(2-benzyl-2H-5-tetrazo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR4 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
GRIA3 (RAT)	BDBM50211399 ((RS)-2-amino-3-[3-hydroxy-5-(2-benzyl-2H-5-tetrazo...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR3 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate kainate (RAT)	BDBM50031704 ((2S,4R)-2-Amino-4-methyl-pentanedioic acid \| (2S,4...) Show SMILES C[C@H](C[C@H](N)C(O)=O)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	0.663	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR5				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 4 (Rattus norvegicus)	BDBM50166285 ((RS)-2-amino-3-[3-hydroxy-5-(2-propyl-2H-5-tetrazo...) Show SMILES CCCn1nnc(n1)-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR4 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 2 (Rattus norvegicus)	BDBM50211399 ((RS)-2-amino-3-[3-hydroxy-5-(2-benzyl-2H-5-tetrazo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR2 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate kainate (RAT)	BDBM50252103 ((2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-MET...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	1.11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR5				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate kainate (RAT)	BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) Show SMILES Cc1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]SYM 2081 from rat recombinant GluR5 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
GRIA3 (RAT)	BDBM50166285 ((RS)-2-amino-3-[3-hydroxy-5-(2-propyl-2H-5-tetrazo...) Show SMILES CCCn1nnc(n1)-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR3 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 2 (Rattus norvegicus)	BDBM50166285 ((RS)-2-amino-3-[3-hydroxy-5-(2-propyl-2H-5-tetrazo...) Show SMILES CCCn1nnc(n1)-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR2 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate kainate (RAT)	BDBM50126763 ((S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl...) Show SMILES CC(C)(C)c1o[nH]c(=O)c1C[C@H](N)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEBI CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	2.13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]SYM from rat recombinant GluR5(Q) RNA-edited isoform expressed in baculovirus infected Sf9 cells				J Med Chem 52: 4911-22 (2009) Checked by Author Article DOI: 10.1021/jm900565c BindingDB Entry DOI: 10.7270/Q2R49RP9
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic AMPA (Homo sapiens (Human))	BDBM50166288 ((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL MMDB PC cid PC sid UniChem Similars	MMDB Article PubMed	2.24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity for ionotropic Glutamate receptor AMPA 3 expressed in Sf9 cells				J Med Chem 48: 3438-42 (2005) Article DOI: 10.1021/jm050014l BindingDB Entry DOI: 10.7270/Q2H70FBJ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 4 (Rattus norvegicus)	BDBM50166287 ((RS)-2-amino-3-[3-hydroxy-5-(2-isopropyl-2H-5-tetr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR4 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate kainate (RAT)	BDBM50060627 ((S)-2-Amino-3-(5-iodo-2,4-dioxo-3,4-dihydro-2H-pyr...) Show SMILES N[C@@H](Cn1cc(I)c(=O)[nH]c1=O)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR5(Q)1b expressed in Sf9 cells				J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R
					More data for this Ligand-Target Pair
Glutamate kainate (RAT)	BDBM50126764 ((S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta...) Show SMILES N[C@@H](CC1=CCCCc2o[nH]c(=O)c12)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL DrugBank MMDB PC cid PC sid UniChem Similars	Article PubMed	2.57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]SYM from rat recombinant GluR5(Q) RNA-edited isoform expressed in baculovirus infected Sf9 cells				J Med Chem 52: 4911-22 (2009) Checked by Author Article DOI: 10.1021/jm900565c BindingDB Entry DOI: 10.7270/Q2R49RP9
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic AMPA (Homo sapiens (Human))	BDBM50166288 ((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity for ionotropic Glutamate receptor AMPA 4 expressed in Sf9 cells				J Med Chem 48: 3438-42 (2005) Article DOI: 10.1021/jm050014l BindingDB Entry DOI: 10.7270/Q2H70FBJ
					More data for this Ligand-Target Pair				3D Structure (docked)
Glutamate receptor 1 (GluA1) (Rattus norvegicus (Rat))	BDBM50060635 ((S)-2-Amino-3-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-p...) Show SMILES N[C@@H](Cn1cc(F)c(=O)[nH]c1=O)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL					Assay Description Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR1 expressed in Sf9 cells				J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R
					More data for this Ligand-Target Pair
Glutamate kainate (RAT)	BDBM50166286 ((RS)-2-amino-3-[3-hydroxy-5-(2-ethyl-2H-5-tetrazol...) Show SMILES CCn1nnc(n1)-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]SYM 2081 from rat recombinant GluR5 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 2 (Rattus norvegicus)	BDBM50166287 ((RS)-2-amino-3-[3-hydroxy-5-(2-isopropyl-2H-5-tetr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR2 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate kainate (RAT)	BDBM50426285 (CHEMBL2312403) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluKK1(Q)1b receptor expressed in sf9 cells by liquid scintillati...				J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
GRIA3 (RAT)	BDBM50166287 ((RS)-2-amino-3-[3-hydroxy-5-(2-isopropyl-2H-5-tetr...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR3 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate kainate (RAT)	BDBM50252051 ((2S,4R)-2-amino-4-(3-(methylamino)-3-oxopropyl)pen...) Show SMILES CNC(=O)CC[C@H](C[C@H](N)C(O)=O)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	3.81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR5				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate (Rattus norvegicus)	BDBM50252103 ((2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-MET...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	3.84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
GRIA2 (Homo sapiens (Human))	BDBM50166288 ((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	3.89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity for ionotropic Glutamate receptor AMPA 2 expressed in Sf9 cells				J Med Chem 48: 3438-42 (2005) Article DOI: 10.1021/jm050014l BindingDB Entry DOI: 10.7270/Q2H70FBJ
					More data for this Ligand-Target Pair
Glutamate kainate (RAT)	BDBM50349983 (CHEMBL1812596) Show SMILES N[C@@H](Cn1c2cscc2c(=O)[nH]c1=O)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat GluK1 expressed in Sf9 cells				J Med Chem 54: 4793-805 (2011) Article DOI: 10.1021/jm2004078 BindingDB Entry DOI: 10.7270/Q2RR1ZM2
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, AMPA 2 (Rattus norvegicus)	BDBM50060635 ((S)-2-Amino-3-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-p...) Show SMILES N[C@@H](Cn1cc(F)c(=O)[nH]c1=O)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development (NatSynDrugs) Curated by ChEMBL					Assay Description Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR2(R) expressed in Sf9 cells				J Med Chem 51: 6614-8 (2008) Article DOI: 10.1021/jm800865a BindingDB Entry DOI: 10.7270/Q261117R
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic kainate 4 (Rattus norvegicus)	BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Binding affinity to rat cloned KA1 receptor				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate kainate (RAT)	BDBM50295042 ((S)-2-Amino-3-((RS)-3-hydroxy-8-methyl-7,8-dihydro...) Show SMILES CC1CCC=C(C[C@H](N)C(O)=O)c2c1o[nH]c2=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.08	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]SYM from rat recombinant GluR5(Q) RNA-edited isoform expressed in baculovirus infected Sf9 cells				J Med Chem 52: 4911-22 (2009) Checked by Author Article DOI: 10.1021/jm900565c BindingDB Entry DOI: 10.7270/Q2R49RP9
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (GluA1) (Rattus norvegicus (Rat))	BDBM50166285 ((RS)-2-amino-3-[3-hydroxy-5-(2-propyl-2H-5-tetrazo...) Show SMILES CCCn1nnc(n1)-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR1 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate kainate (RAT)	BDBM50252920 ((S)-1-[2'-Amino-2'-carboxyethyl]-5,7-dihydrothieno...) Show SMILES N[C@@H](Cn1c2CSCc2c(=O)[nH]c1=O)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid PDB UniChem	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat GluK1 expressed in Sf9 cells				J Med Chem 54: 4793-805 (2011) Article DOI: 10.1021/jm2004078 BindingDB Entry DOI: 10.7270/Q2RR1ZM2
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
GRIA1 (Homo sapiens (Human))	BDBM50166288 ((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	5.22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity for ionotropic Glutamate receptor AMPA 1 expressed in Sf9 cells				J Med Chem 48: 3438-42 (2005) Article DOI: 10.1021/jm050014l BindingDB Entry DOI: 10.7270/Q2H70FBJ
					More data for this Ligand-Target Pair
Glutamate kainate (RAT)	BDBM50252922 ((S)-1-(2'-Amino-2'-carboxyethyl)thieno[3,2-d]pyrim...) Show SMILES N[C@@H](Cn1c2ccsc2c(=O)[nH]c1=O)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat GluK1 expressed in Sf9 cells				J Med Chem 54: 4793-805 (2011) Article DOI: 10.1021/jm2004078 BindingDB Entry DOI: 10.7270/Q2RR1ZM2
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate kainate (RAT)	BDBM50166285 ((RS)-2-amino-3-[3-hydroxy-5-(2-propyl-2H-5-tetrazo...) Show SMILES CCCn1nnc(n1)-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]SYM 2081 from rat recombinant GluR5 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate (Rattus norvegicus)	BDBM50031704 ((2S,4R)-2-Amino-4-methyl-pentanedioic acid \| (2S,4...) Show SMILES C[C@H](C[C@H](N)C(O)=O)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	5.69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate kainate (RAT)	BDBM50349981 (CHEMBL1812598) Show SMILES N[C@@H](Cn1c2sccc2c(=O)[nH]c1=O)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	5.89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat GluK1 expressed in Sf9 cells				J Med Chem 54: 4793-805 (2011) Article DOI: 10.1021/jm2004078 BindingDB Entry DOI: 10.7270/Q2RR1ZM2
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Ionotropic glutamate receptor kainate 2/5 (Rattus norvegicus)	BDBM50252103 ((2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-MET...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	6.04	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR6				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Glutamate kainate (RAT)	BDBM50252050 ((2S,4R)-2-amino-4-(3-amino-3-oxopropyl)pentanedioi...) Show SMILES N[C@@H](C[C@@H](CCC(N)=O)C(O)=O)C(O)=O Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite Blaise Pascal Curated by ChEMBL					Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR5				J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6
Universite Blaise Pascal Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 1 (GluA1) (Rattus norvegicus (Rat))	BDBM50211399 ((RS)-2-amino-3-[3-hydroxy-5-(2-benzyl-2H-5-tetrazo...) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from rat recombinant GluR1 expressed in Sf9 cells				J Med Chem 50: 2408-14 (2007) Article DOI: 10.1021/jm061439q BindingDB Entry DOI: 10.7270/Q2DZ0809
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair

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