BindingDB PrimarySearch

Found 910 hits with Last Name = 'pinto' and Initial = 'a'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50069989 ((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	9.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (Homo sapiens (Human))	BDBM50123588 (CHEMBL297258) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Competitive inhibition of human FolD dehydrogenase activity				J Med Chem 58: 7938-48 (2015) Article DOI: 10.1021/acs.jmedchem.5b00687 BindingDB Entry DOI: 10.7270/Q2SN0BSR
University of Dundee Curated by ChEMBL					More data for this Ligand-Target Pair
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50021350 (CHEMBL3287940) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50021352 (CHEMBL3287943) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50021348 (CHEMBL3287937) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50021353 (CHEMBL3287944) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50021355 (CHEMBL3287946) Show SMILES CC(C)CCNC(=O)CCn1cc(Br)c2ncccc2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50021351 (CHEMBL3287942) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50434761 (CHEMBL2385819) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome component C5 (Homo sapiens (Human))	BDBM50021350 (CHEMBL3287940) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-chymotrypsin (Bos taurus (bovine))	BDBM50021352 (CHEMBL3287943) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of bovine pancreatic alpha-chymotrypsin using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome component C5 (Homo sapiens (Human))	BDBM50021352 (CHEMBL3287943) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50434763 (CHEMBL2385817) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50021349 (CHEMBL3287939) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome component C5 (Homo sapiens (Human))	BDBM50021348 (CHEMBL3287937) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome component C5 (Homo sapiens (Human))	BDBM50021349 (CHEMBL3287939) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	990	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome component C5 (Homo sapiens (Human))	BDBM50021351 (CHEMBL3287942) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome component C5 (Homo sapiens (Human))	BDBM50434763 (CHEMBL2385817) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome component C5 (Homo sapiens (Human))	BDBM50021353 (CHEMBL3287944) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50021356 (CHEMBL3287947) Show SMILES CC(C)CCNC(=O)Cn1ccc2ccc(Br)cc2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.34E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-chymotrypsin (Bos taurus (bovine))	BDBM50069989 ((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of bovine pancreatic alpha-chymotrypsin using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Rhodesain (Trypanosoma brucei rhodesiense)	BDBM50128352 (CHEMBL3629184) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.62E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-7-amino-4-methylcoumarin assessed as substrate hydrolysis measured by fluore...				Bioorg Med Chem 23: 7053-60 (2015) Article DOI: 10.1016/j.bmc.2015.09.029 BindingDB Entry DOI: 10.7270/Q2ZW1NQX
University of Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Rhodesain (Trypanosoma brucei rhodesiense)	BDBM50128350 (CHEMBL3629186) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.73E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-7-amino-4-methylcoumarin assessed as substrate hydrolysis measured by fluore...				Bioorg Med Chem 23: 7053-60 (2015) Article DOI: 10.1016/j.bmc.2015.09.029 BindingDB Entry DOI: 10.7270/Q2ZW1NQX
University of Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Rhodesain (Trypanosoma brucei rhodesiense)	BDBM50128351 (CHEMBL3629185) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-7-amino-4-methylcoumarin assessed as substrate hydrolysis measured by fluore...				Bioorg Med Chem 23: 7053-60 (2015) Article DOI: 10.1016/j.bmc.2015.09.029 BindingDB Entry DOI: 10.7270/Q2ZW1NQX
University of Messina Curated by ChEMBL					More data for this Ligand-Target Pair
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50021354 (CHEMBL3287945) Show SMILES CC(C)CCNC(=O)CCn1ccc2ncccc2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.57E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of 20S proteasome in human erythrocytes using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Rhodesain (Trypanosoma brucei rhodesiense)	BDBM50128345 (CHEMBL3629346) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.81E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-7-amino-4-methylcoumarin assessed as substrate hydrolysis measured by fluore...				Bioorg Med Chem 23: 7053-60 (2015) Article DOI: 10.1016/j.bmc.2015.09.029 BindingDB Entry DOI: 10.7270/Q2ZW1NQX
University of Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Rhodesain (Trypanosoma brucei rhodesiense)	BDBM50128349 (CHEMBL3629339) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-7-amino-4-methylcoumarin assessed as substrate hydrolysis measured by fluore...				Bioorg Med Chem 23: 7053-60 (2015) Article DOI: 10.1016/j.bmc.2015.09.029 BindingDB Entry DOI: 10.7270/Q2ZW1NQX
University of Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Rhodesain (Trypanosoma brucei rhodesiense)	BDBM50128354 (CHEMBL3629181) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-7-amino-4-methylcoumarin assessed as substrate hydrolysis measured by fluore...				Bioorg Med Chem 23: 7053-60 (2015) Article DOI: 10.1016/j.bmc.2015.09.029 BindingDB Entry DOI: 10.7270/Q2ZW1NQX
University of Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Rhodesain (Trypanosoma brucei rhodesiense)	BDBM50128347 (CHEMBL3629341) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.52E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-7-amino-4-methylcoumarin assessed as substrate hydrolysis measured by fluore...				Bioorg Med Chem 23: 7053-60 (2015) Article DOI: 10.1016/j.bmc.2015.09.029 BindingDB Entry DOI: 10.7270/Q2ZW1NQX
University of Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Rhodesain (Trypanosoma brucei rhodesiense)	BDBM50128348 (CHEMBL3629340) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-7-amino-4-methylcoumarin assessed as substrate hydrolysis measured by fluore...				Bioorg Med Chem 23: 7053-60 (2015) Article DOI: 10.1016/j.bmc.2015.09.029 BindingDB Entry DOI: 10.7270/Q2ZW1NQX
University of Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-chymotrypsin (Bos taurus (bovine))	BDBM50021349 (CHEMBL3287939) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.11E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of bovine pancreatic alpha-chymotrypsin using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM108063 (2‐({4‐[(3‐ aminopropyl)(benzyl)a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article PubMed	1.20E+4	-29.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.					Assay Description The reaction mixture (final volume 200 µL) contained 5 µg/mL MAO-A or MAO-B in a 50 mM sodium phosphate buffer pH 7.4, 1 mM p-tyramine (sub...				Chem Biol Drug Des 83: 401-10 (2014) Article DOI: 10.1111/cbdd.12255 BindingDB Entry DOI: 10.7270/Q2K072W1
					More data for this Ligand-Target Pair
Rhodesain (Trypanosoma brucei rhodesiense)	BDBM50128346 (CHEMBL3629344) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-7-amino-4-methylcoumarin assessed as substrate hydrolysis measured by fluore...				Bioorg Med Chem 23: 7053-60 (2015) Article DOI: 10.1016/j.bmc.2015.09.029 BindingDB Entry DOI: 10.7270/Q2ZW1NQX
University of Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Rhodesain (Trypanosoma brucei rhodesiense)	BDBM50128355 (CHEMBL3629180) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.51E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-7-amino-4-methylcoumarin assessed as substrate hydrolysis measured by fluore...				Bioorg Med Chem 23: 7053-60 (2015) Article DOI: 10.1016/j.bmc.2015.09.029 BindingDB Entry DOI: 10.7270/Q2ZW1NQX
University of Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Rhodesain (Trypanosoma brucei rhodesiense)	BDBM50128356 (CHEMBL3629179) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.66E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-7-amino-4-methylcoumarin assessed as substrate hydrolysis measured by fluore...				Bioorg Med Chem 23: 7053-60 (2015) Article DOI: 10.1016/j.bmc.2015.09.029 BindingDB Entry DOI: 10.7270/Q2ZW1NQX
University of Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Rhodesain (Trypanosoma brucei rhodesiense)	BDBM50128357 (CHEMBL3629178) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.68E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-7-amino-4-methylcoumarin assessed as substrate hydrolysis measured by fluore...				Bioorg Med Chem 23: 7053-60 (2015) Article DOI: 10.1016/j.bmc.2015.09.029 BindingDB Entry DOI: 10.7270/Q2ZW1NQX
University of Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Proteasome component C5 (Homo sapiens (Human))	BDBM50434761 (CHEMBL2385819) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.76E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Rhodesain (Trypanosoma brucei rhodesiense)	BDBM50128353 (CHEMBL3629183) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.77E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-7-amino-4-methylcoumarin assessed as substrate hydrolysis measured by fluore...				Bioorg Med Chem 23: 7053-60 (2015) Article DOI: 10.1016/j.bmc.2015.09.029 BindingDB Entry DOI: 10.7270/Q2ZW1NQX
University of Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM108061 (Nor-lapachol) Show SMILES CC(C)C=C1C(=O)C(=O)c2ccccc2C1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article PubMed	1.80E+4	-28.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.					Assay Description The reaction mixture (final volume 200 µL) contained 5 µg/mL MAO-A or MAO-B in a 50 mM sodium phosphate buffer pH 7.4, 1 mM p-tyramine (sub...				Chem Biol Drug Des 83: 401-10 (2014) Article DOI: 10.1111/cbdd.12255 BindingDB Entry DOI: 10.7270/Q2K072W1
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM108062 (2‐({4‐[(3‐aminopropyl)(benzyl)am...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article PubMed	2.20E+4	-27.7	n/a	n/a	n/a	n/a	n/a	7.4	37
Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.					Assay Description The reaction mixture (final volume 200 µL) contained 5 µg/mL MAO-A or MAO-B in a 50 mM sodium phosphate buffer pH 7.4, 1 mM p-tyramine (sub...				Chem Biol Drug Des 83: 401-10 (2014) Article DOI: 10.1111/cbdd.12255 BindingDB Entry DOI: 10.7270/Q2K072W1
					More data for this Ligand-Target Pair
Alpha-chymotrypsin (Bos taurus (bovine))	BDBM50021353 (CHEMBL3287944) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.37E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of bovine pancreatic alpha-chymotrypsin using Suc-Leu-Leu-Val-Tyr-AMC as substrate by fluorescence assay				Eur J Med Chem 83: 1-14 (2014) Article DOI: 10.1016/j.ejmech.2014.06.017 BindingDB Entry DOI: 10.7270/Q2DZ09WC
Universit£ degli Studi di Messina Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor (RAT)	BDBM50174516 (5-Amino-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]isoxa...) Show SMILES NC1(CC2ON=C(C2C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Binding affinity for mGluR1 receptor expressed in CHO cells				J Med Chem 48: 6315-25 (2005) Article DOI: 10.1021/jm0504499 BindingDB Entry DOI: 10.7270/Q2PC31X8
Università degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM108063 (2‐({4‐[(3‐ aminopropyl)(benzyl)a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article PubMed	2.80E+4	-27.0	n/a	n/a	n/a	n/a	n/a	7.4	37
Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.					Assay Description The reaction mixture (final volume 200 µL) contained 5 µg/mL MAO-A or MAO-B in a 50 mM sodium phosphate buffer pH 7.4, 1 mM p-tyramine (sub...				Chem Biol Drug Des 83: 401-10 (2014) Article DOI: 10.1111/cbdd.12255 BindingDB Entry DOI: 10.7270/Q2K072W1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor (RAT)	BDBM50174519 ((3aR,5R,6aR)-5-Amino-4,5,6,6a-tetrahydro-3aH-cyclo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Binding affinity for mGluR1 receptor expressed in CHO cells				J Med Chem 48: 6315-25 (2005) Article DOI: 10.1021/jm0504499 BindingDB Entry DOI: 10.7270/Q2PC31X8
Università degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM108061 (Nor-lapachol) Show SMILES CC(C)C=C1C(=O)C(=O)c2ccccc2C1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article PubMed	3.50E+4	-26.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.					Assay Description The reaction mixture (final volume 200 µL) contained 5 µg/mL MAO-A or MAO-B in a 50 mM sodium phosphate buffer pH 7.4, 1 mM p-tyramine (sub...				Chem Biol Drug Des 83: 401-10 (2014) Article DOI: 10.1111/cbdd.12255 BindingDB Entry DOI: 10.7270/Q2K072W1
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM108062 (2‐({4‐[(3‐aminopropyl)(benzyl)am...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article PubMed	4.00E+4	-26.1	n/a	n/a	n/a	n/a	n/a	7.4	37
Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.					Assay Description The reaction mixture (final volume 200 µL) contained 5 µg/mL MAO-A or MAO-B in a 50 mM sodium phosphate buffer pH 7.4, 1 mM p-tyramine (sub...				Chem Biol Drug Des 83: 401-10 (2014) Article DOI: 10.1111/cbdd.12255 BindingDB Entry DOI: 10.7270/Q2K072W1
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM108064 (2‐({4‐[(3‐aminopropyl)(benzyl)am...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article PubMed	5.80E+4	-25.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.					Assay Description The reaction mixture (final volume 200 µL) contained 5 µg/mL MAO-A or MAO-B in a 50 mM sodium phosphate buffer pH 7.4, 1 mM p-tyramine (sub...				Chem Biol Drug Des 83: 401-10 (2014) Article DOI: 10.1111/cbdd.12255 BindingDB Entry DOI: 10.7270/Q2K072W1
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM108060 (4-hydroxy-3-(3-methylbut-2-enyl)naphthalene-1,2-di...) Show SMILES CC(C)=CCC1C(=O)C(=O)c2ccccc2C1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	5.90E+4	-25.1	n/a	n/a	n/a	n/a	n/a	7.4	37
Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.					Assay Description The reaction mixture (final volume 200 µL) contained 5 µg/mL MAO-A or MAO-B in a 50 mM sodium phosphate buffer pH 7.4, 1 mM p-tyramine (sub...				Chem Biol Drug Des 83: 401-10 (2014) Article DOI: 10.1111/cbdd.12255 BindingDB Entry DOI: 10.7270/Q2K072W1
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM108064 (2‐({4‐[(3‐aminopropyl)(benzyl)am...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article PubMed	6.30E+4	-24.9	n/a	n/a	n/a	n/a	n/a	7.4	37
Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-909, Brazil.					Assay Description The reaction mixture (final volume 200 µL) contained 5 µg/mL MAO-A or MAO-B in a 50 mM sodium phosphate buffer pH 7.4, 1 mM p-tyramine (sub...				Chem Biol Drug Des 83: 401-10 (2014) Article DOI: 10.1111/cbdd.12255 BindingDB Entry DOI: 10.7270/Q2K072W1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor (RAT)	BDBM50174516 (5-Amino-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]isoxa...) Show SMILES NC1(CC2ON=C(C2C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Milano Curated by ChEMBL					Assay Description Binding affinity for mGluR1 receptor expressed in CHO cells				J Med Chem 48: 6315-25 (2005) Article DOI: 10.1021/jm0504499 BindingDB Entry DOI: 10.7270/Q2PC31X8
Università degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair

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