Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G-protein coupled receptor 6 (Homo sapiens (Human)) | BDBM412953![]() (US10406157, Compound Formula 1) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | UniChem | US Patent | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The inhibition constant (Ki) from a GPR6 competition binding assay and the IC50 values from a hERG functional assay for the compound of Formula 1 (Ex... | US Patent US10406157 (2019) BindingDB Entry DOI: 10.7270/Q2J105HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 6 (Homo sapiens (Human)) | BDBM191037![]() (US10077266, Example 149 | US10406157, Compound A |...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem Similars | US Patent | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description The inhibition constant (Ki) from a GPR6 competition binding assay and the IC50 values from a hERG functional assay for the compound of Formula 1 (Ex... | US Patent US10406157 (2019) BindingDB Entry DOI: 10.7270/Q2J105HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263478![]() ((s)-2-(6,8-dimethyl-4-oxobenzo[d][1,2,3]triazin-3(...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 10 | -42.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263499![]() ((s)?n-(1-(2-fluoro-4-(trifluoromethyl)phenyl)ethyl...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 11 | -42.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263461![]() ((s)-2-(6,8-dichloro-4-oxobenzo[d][1,2,3]triazin-3(...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 26 | -40.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263493![]() ((s)-2-(5-methoxy-4-oxobenzo[d][1,2,3]triazin-3 (4h...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 26 | -40.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263490![]() ((s)-2-(5-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 33 | -39.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263504![]() ((s)?n-(1-(2-fluoro-4-(trifluoromethoxy)phenyl)ethy...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 33 | -39.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263484![]() ((s)?n-(1-(2,4-dimethylphenyl)ethyl)-2-(6-fluoro-4-...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 39 | -39.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263487![]() ((s)-2-(6-fluoro-4-oxobenzo[d][1,2,3]triazin-3(4h)-...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 42 | -39.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263369![]() ((s)-2-(5-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 48 | -38.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263453![]() ((s)-2-(6-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 58 | -38.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263420![]() ((s)?n-(1-(2,4-dimethylphenyl)ethyl)-2-(4-oxobenzo[...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 63 | -38.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263459![]() ((s)-2-(8-methyl-4-oxobenzo[d][1,2,3]triazin-3(4h)-...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 72 | -37.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263486![]() ((s)?n-(1-(2-fluoro-4-methylphenyl)ethyl)-2-(6-fluo...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 77 | -37.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263482![]() ((s)-2-(8-fluoro-6-methyl-4-oxobenzo[d][1,2,3]triaz...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 85 | -37.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263474![]() ((s)-2-(5-methyl-4-oxobenzo[d][1,2,3]triazin-3 (4h)...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 92 | -37.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263503![]() ((s)?n-(1-(2-fluoro-4-(trifluoromethoxy)phenyl)ethy...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 93 | -37.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263496![]() ((s)-2-(6-fluoro-4-oxobenzo[d][1,2,3]triazin-3(4h)-...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 106 | -37.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263457![]() ((s)-2-(8-chloro-4-oxobenzo[d][1,2,3]triazin-3(4h)-...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 110 | -36.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263492![]() ((s)-2-(6-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 115 | -36.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263509![]() (US10561662, Example 81 | US9556130, test 81 | n-(2...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 117 | -36.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263368![]() ((s)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 119 | -36.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263501![]() ((s)?n-(1-(4-(difluoromethoxy)phenyl)ethyl)-2-(5-me...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 120 | -36.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263502![]() ((s)?n-(1-(2-fluoro-4-(trifluoromethoxy)phenyl)ethy...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 120 | -36.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263489![]() ((s)-2-(6-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 128 | -36.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263440![]() ((s)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 148 | -36.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263497![]() ((s)?n-(1-(2-fluoro-4-(trifluoromethyl)phenyl)ethyl...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 152 | -36.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263485![]() ((s)?n-(1-(2-fluoro-4-methylphenyl)ethyl)-2-(4-oxob...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 171 | -35.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263456![]() ((s)-2-(7-chloro-4-oxobenzo[d][1,2,3]triazin-3(4h)-...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 173 | -35.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263463![]() ((s)-2-(6-methyl-4-oxobenzo[d][1,2,3]triazin-3(4h)-...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 179 | -35.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263479![]() ((s)-2-(6,8-dimethyl-4-oxobenzo[d][1,2,3]triazin-3(...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 179 | -35.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263445![]() ((s)-2-(6-fluoro-4-oxobenzo[d][1,2,3]triazin-3(4h)-...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 182 | -35.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263511![]() ((s)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 183 | -35.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263454![]() ((s)-2-(6-chloro-4-oxobenzo[d][1,2,3]triazin-3 (4h)...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 189 | -35.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263462![]() ((s)-2-(6,8-dichloro-4-oxobenzo[d][1,2,3]triazin-3(...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 190 | -35.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263512![]() ((s)-2-(4-oxobenzo[d][1,2,3]triazin-3 (4h)-yl)-n-(1...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 214 | -35.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263488![]() ((s)-2-(7-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 218 | -35.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263391![]() ((s)?n-(1-(4-chlorophenyl)ethyl)-2-(4-oxobenzo[d][1...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 228 | -35.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263494![]() ((s)-2-(8-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 240 | -35.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263500![]() ((s)?n-(1-(4-(difluoromethoxy)phenyl)ethyl)-2-(6-fl...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 282 | -34.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263469![]() ((s)-2-(7-methyl-4-oxobenzo[d][1,2,3]triazin-3(4h)-...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 347 | -34.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263495![]() ((s)-2-(8-methoxy-4-oxobenzo[d][1,2,3]triazin-3 (4h...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 352 | -34.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263491![]() ((s)-2-(7-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 375 | -34.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263480![]() ((s)-2-(4-oxo-6-(trifluoromethyl)benzo[d][1,2,3]tri...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 435 | -33.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263471![]() ((s)-2-(7-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 437 | -33.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263467![]() ((s)-2-(5-fluoro-4-oxobenzo[d][1,2,3]triazin-3(4h)-...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 459 | -33.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263370![]() ((s)-2-(4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 467 | -33.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263460![]() ((s)?n-(1-(4-methoxyphenyl)ethyl)-2-(8-methyl-4-oxo...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 526 | -33.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled receptor 139 (Homo sapiens (Human)) | BDBM263477![]() ((s)?n-(1-(4-methoxyphenyl)ethyl)-2-(5-methyl-4-oxo...) | UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 533 | -33.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Takeda Pharmaceutical Co., Ltd US Patent | Assay Description This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec... | US Patent US9556130 (2017) BindingDB Entry DOI: 10.7270/Q29025SJ | |||||||||||
More data for this Ligand-Target Pair |
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