BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 50 hits with Last Name = 'stengel' and Initial = 'pw'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
LTB4R


(HUMAN)
BDBM50029464
PNG
(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-4'-fluoro-2-hydr...)
Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccc(cc3c2=O)C(O)=O)c1CCC(O)=O)-c1ccc(F)cc1
Show InChI InChI=1S/C34H29FO9/c1-2-19-16-25(20-4-7-22(35)8-5-20)27(36)18-30(19)43-15-3-14-42-28-12-9-24-32(39)26-17-21(34(40)41)6-11-29(26)44-33(24)23(28)10-13-31(37)38/h4-9,11-12,16-18,36H,2-3,10,13-15H2,1H3,(H,37,38)(H,40,41)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
0.0400n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptor


Citation and Details
More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50029477
PNG
(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-2-hydroxy-biphen...)
Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccc(cc3c2=O)C(O)=O)c1CCC(O)=O)-c1ccccc1
Show InChI InChI=1S/C34H30O9/c1-2-20-17-25(21-7-4-3-5-8-21)27(35)19-30(20)42-16-6-15-41-28-13-10-24-32(38)26-18-22(34(39)40)9-12-29(26)43-33(24)23(28)11-14-31(36)37/h3-5,7-10,12-13,17-19,35H,2,6,11,14-16H2,1H3,(H,36,37)(H,39,40)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
0.110n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptor


Citation and Details
More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50013889
PNG
((5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,...)
Show SMILES CCCCC\C=C/C[C@@H](O)\C=C\C=C\C=C/[C@@H](O)CCCC(O)=O
Show InChI InChI=1S/C20H32O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h6-11,14-15,18-19,21-22H,2-5,12-13,16-17H2,1H3,(H,23,24)/b8-7+,9-6-,14-10+,15-11-/t18-,19-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
PDB
UniChem

Patents


Similars

PubMed
0.120n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptor


Citation and Details
More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50029464
PNG
(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-4'-fluoro-2-hydr...)
Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccc(cc3c2=O)C(O)=O)c1CCC(O)=O)-c1ccc(F)cc1
Show InChI InChI=1S/C34H29FO9/c1-2-19-16-25(20-4-7-22(35)8-5-20)27(36)18-30(19)43-15-3-14-42-28-12-9-24-32(39)26-17-21(34(40)41)6-11-29(26)44-33(24)23(28)10-13-31(37)38/h4-9,11-12,16-18,36H,2-3,10,13-15H2,1H3,(H,37,38)(H,40,41)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
0.470n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptor


Citation and Details
More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50029477
PNG
(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-2-hydroxy-biphen...)
Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccc(cc3c2=O)C(O)=O)c1CCC(O)=O)-c1ccccc1
Show InChI InChI=1S/C34H30O9/c1-2-20-17-25(21-7-4-3-5-8-21)27(35)19-30(20)42-16-6-15-41-28-13-10-24-32(38)26-18-22(34(39)40)9-12-29(26)43-33(24)23(28)11-14-31(36)37/h3-5,7-10,12-13,17-19,35H,2,6,11,14-16H2,1H3,(H,36,37)(H,39,40)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
0.570n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptor


Citation and Details
More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50029482
PNG
(6-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propoxy]...)
Show SMILES CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(oc3ccc(cc3c2=O)C(O)=O)c1CCC(O)=O
Show InChI InChI=1S/C30H28O10/c1-3-17-13-21(16(2)31)23(32)15-26(17)39-12-4-11-38-24-9-6-20-28(35)22-14-18(30(36)37)5-8-25(22)40-29(20)19(24)7-10-27(33)34/h5-6,8-9,13-15,32H,3-4,7,10-12H2,1-2H3,(H,33,34)(H,36,37)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
1.20n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptor


Citation and Details
More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50029482
PNG
(6-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propoxy]...)
Show SMILES CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(oc3ccc(cc3c2=O)C(O)=O)c1CCC(O)=O
Show InChI InChI=1S/C30H28O10/c1-3-17-13-21(16(2)31)23(32)15-26(17)39-12-4-11-38-24-9-6-20-28(35)22-14-18(30(36)37)5-8-25(22)40-29(20)19(24)7-10-27(33)34/h5-6,8-9,13-15,32H,3-4,7,10-12H2,1-2H3,(H,33,34)(H,36,37)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
1.20n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptor


Citation and Details
More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50013889
PNG
((5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,...)
Show SMILES CCCCC\C=C/C[C@@H](O)\C=C\C=C\C=C/[C@@H](O)CCCC(O)=O
Show InChI InChI=1S/C20H32O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h6-11,14-15,18-19,21-22H,2-5,12-13,16-17H2,1H3,(H,23,24)/b8-7+,9-6-,14-10+,15-11-/t18-,19-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
PDB
UniChem

Patents


Similars

PubMed
1.90n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptor


Citation and Details
More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50280292
PNG
(7-[3-(2-Ethyl-5-hydroxy-4-methoxy-phenoxy)-propoxy...)
Show SMILES CCCc1c(OCCCOc2cc(O)c(OC)cc2CC)ccc2CCC(Oc12)C(O)=O
Show InChI InChI=1S/C25H32O7/c1-4-7-18-20(10-8-17-9-11-21(25(27)28)32-24(17)18)30-12-6-13-31-22-15-19(26)23(29-3)14-16(22)5-2/h8,10,14-15,21,26H,4-7,9,11-13H2,1-3H3,(H,27,28)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
1.90n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay


Bioorg Med Chem Lett 2: 1675-1680 (1992)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50280291
PNG
(7-[3-(4-Ethoxy-2-ethyl-5-hydroxy-phenoxy)-propoxy]...)
Show SMILES CCCc1c(OCCCOc2cc(O)c(OCC)cc2CC)ccc2CCC(Oc12)C(O)=O
Show InChI InChI=1S/C26H34O7/c1-4-8-19-21(11-9-18-10-12-22(26(28)29)33-25(18)19)31-13-7-14-32-23-16-20(27)24(30-6-3)15-17(23)5-2/h9,11,15-16,22,27H,4-8,10,12-14H2,1-3H3,(H,28,29)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
3.5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay


Bioorg Med Chem Lett 2: 1675-1680 (1992)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50029460
PNG
(3-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...)
Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccccc3c2=O)c1CCC(O)=O)-c1ccc(F)cc1
Show InChI InChI=1S/C33H29FO7/c1-2-20-18-26(21-8-10-22(34)11-9-21)27(35)19-30(20)40-17-5-16-39-28-14-12-25-32(38)23-6-3-4-7-29(23)41-33(25)24(28)13-15-31(36)37/h3-4,6-12,14,18-19,35H,2,5,13,15-17H2,1H3,(H,36,37)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
4n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptor


Citation and Details
More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50281875
PNG
(CHEMBL15648 | {3-[3-(4-Acetyl-2-ethyl-5-hydroxy-ph...)
Show SMILES CCCc1c(OCCCOc2cc(O)c(cc2CC)C(C)=O)cccc1OCC(O)=O
Show InChI InChI=1S/C24H30O7/c1-4-8-18-21(9-6-10-22(18)31-15-24(27)28)29-11-7-12-30-23-14-20(26)19(16(3)25)13-17(23)5-2/h6,9-10,13-14,26H,4-5,7-8,11-12,15H2,1-3H3,(H,27,28)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against LTB4 receptor in guinea pig membrane


Bioorg Med Chem Lett 3: 1147-1152 (1993)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50281873
PNG
(CHEMBL15559 | Sodium; 7-[3-(4-acetyl-2-ethyl-5-hyd...)
Show SMILES CCCc1c(OCCCOc2cc(O)c(cc2CC)C(C)=O)ccc2CCC(Oc12)C([O-])=O
Show InChI InChI=1S/C26H32O7/c1-4-7-19-22(10-8-18-9-11-23(26(29)30)33-25(18)19)31-12-6-13-32-24-15-21(28)20(16(3)27)14-17(24)5-2/h8,10,14-15,23,28H,4-7,9,11-13H2,1-3H3,(H,29,30)/p-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
10n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against LTB4 receptor in guinea pig membrane


Bioorg Med Chem Lett 3: 1147-1152 (1993)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50029448
PNG
(3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propo...)
Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccccc3c2=O)c1CCC(O)=O)-c1ccccc1
Show InChI InChI=1S/C33H30O7/c1-2-21-19-26(22-9-4-3-5-10-22)27(34)20-30(21)39-18-8-17-38-28-15-13-25-32(37)23-11-6-7-12-29(23)40-33(25)24(28)14-16-31(35)36/h3-7,9-13,15,19-20,34H,2,8,14,16-18H2,1H3,(H,35,36)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
12n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptor


Citation and Details
More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50036750
PNG
(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Show SMILES CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[n-]n2)cc1O
Show InChI InChI=1S/C19H29N4O3/c1-5-14-12-17(25-6-2)15(24)13-16(14)26-11-9-7-8-10-19(3,4)18-20-22-23-21-18/h12-13H,5-11H2,1-4H3,(H-,20,21,22,23,24)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
14n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay


Bioorg Med Chem Lett 2: 1675-1680 (1992)

More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50036750
PNG
(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Show SMILES CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[n-]n2)cc1O
Show InChI InChI=1S/C19H29N4O3/c1-5-14-12-17(25-6-2)15(24)13-16(14)26-11-9-7-8-10-19(3,4)18-20-22-23-21-18/h12-13H,5-11H2,1-4H3,(H-,20,21,22,23,24)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
14n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for receptor binding against [3H]-LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay


Bioorg Med Chem Lett 2: 1669-1674 (1992)

More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50281874
PNG
(6-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...)
Show SMILES CCCc1cc(OCCCOc2ccc(C(C)=O)c(OC)c2CCC)cc2CCC(Oc12)C(O)=O
Show InChI InChI=1S/C28H36O7/c1-5-8-19-16-21(17-20-10-12-25(28(30)31)35-26(19)20)33-14-7-15-34-24-13-11-22(18(3)29)27(32-4)23(24)9-6-2/h11,13,16-17,25H,5-10,12,14-15H2,1-4H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
15n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against LTB4 receptor in guinea pig membrane


Bioorg Med Chem Lett 3: 1147-1152 (1993)

More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50281876
PNG
(2-{3-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propo...)
Show SMILES CCCc1c(OCCCOc2cc(O)c(cc2CC)C(C)=O)cccc1OC(CC)C(O)=O
Show InChI InChI=1S/C26H34O7/c1-5-10-19-23(11-8-12-24(19)33-22(7-3)26(29)30)31-13-9-14-32-25-16-21(28)20(17(4)27)15-18(25)6-2/h8,11-12,15-16,22,28H,5-7,9-10,13-14H2,1-4H3,(H,29,30)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
16n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition against LTB4 receptor in human neutrophil


Bioorg Med Chem Lett 3: 1147-1152 (1993)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50281877
PNG
(2-{3-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propo...)
Show SMILES CCCc1c(OCCCOc2cc(O)c(cc2CC)C(C)=O)cccc1OC(C)C(O)=O
Show InChI InChI=1S/C25H32O7/c1-5-9-19-22(10-7-11-23(19)32-17(4)25(28)29)30-12-8-13-31-24-15-21(27)20(16(3)26)14-18(24)6-2/h7,10-11,14-15,17,27H,5-6,8-9,12-13H2,1-4H3,(H,28,29)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
19n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against LTB4 receptor in guinea pig membrane


Bioorg Med Chem Lett 3: 1147-1152 (1993)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50029448
PNG
(3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propo...)
Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccccc3c2=O)c1CCC(O)=O)-c1ccccc1
Show InChI InChI=1S/C33H30O7/c1-2-21-19-26(22-9-4-3-5-10-22)27(34)20-30(21)39-18-8-17-38-28-15-13-25-32(37)23-11-6-7-12-29(23)40-33(25)24(28)14-16-31(35)36/h3-7,9-13,15,19-20,34H,2,8,14,16-18H2,1H3,(H,35,36)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
22n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptor


Citation and Details
More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50280286
PNG
(4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraazol-5-yl)h...)
Show SMILES CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[n-]n2)cc1O
Show InChI InChI=1S/C22H35N4O3/c1-5-7-10-13-29-20-15-17(6-2)19(16-18(20)27)28-14-11-8-9-12-22(3,4)21-23-25-26-24-21/h15-16H,5-14H2,1-4H3,(H-,23,24,25,26,27)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
23n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for receptor binding against [3H]-LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assa...


Bioorg Med Chem Lett 2: 1669-1674 (1992)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50280290
PNG
(4-ethyl-2-methoxy-5-[6-methyl-6-(2H-1,2,3,4-tetraa...)
Show SMILES CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1
Show InChI InChI=1S/C18H27N4O3/c1-5-13-11-16(24-4)14(23)12-15(13)25-10-8-6-7-9-18(2,3)17-19-21-22-20-17/h11-12H,5-10H2,1-4H3,(H-,19,20,21,22,23)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
25n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for receptor binding against [3H]-LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assa...


Bioorg Med Chem Lett 2: 1669-1674 (1992)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50280290
PNG
(4-ethyl-2-methoxy-5-[6-methyl-6-(2H-1,2,3,4-tetraa...)
Show SMILES CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1
Show InChI InChI=1S/C18H27N4O3/c1-5-13-11-16(24-4)14(23)12-15(13)25-10-8-6-7-9-18(2,3)17-19-21-22-20-17/h11-12H,5-10H2,1-4H3,(H-,19,20,21,22,23)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
25n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in guinea pig lung membrane binding assay


Bioorg Med Chem Lett 2: 1675-1680 (1992)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50029460
PNG
(3-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...)
Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccccc3c2=O)c1CCC(O)=O)-c1ccc(F)cc1
Show InChI InChI=1S/C33H29FO7/c1-2-20-18-26(21-8-10-22(34)11-9-21)27(35)19-30(20)40-17-5-16-39-28-14-12-25-32(38)23-6-3-4-7-29(23)41-33(25)24(28)13-15-31(36)37/h3-4,6-12,14,18-19,35H,2,5,13,15-17H2,1H3,(H,36,37)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
36n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptor


Citation and Details
More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50280287
PNG
(4-ethyl-2-isopropoxy-5-[6-methyl-6-(2H-1,2,3,4-tet...)
Show SMILES CCc1cc(OC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1
Show InChI InChI=1S/C20H31N4O3/c1-6-15-12-18(27-14(2)3)16(25)13-17(15)26-11-9-7-8-10-20(4,5)19-21-23-24-22-19/h12-14H,6-11H2,1-5H3,(H-,21,22,23,24,25)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
53n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for receptor binding against [3H]-LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay


Bioorg Med Chem Lett 2: 1669-1674 (1992)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50036749
PNG
(1-{5-ethyl-2-hydroxy-4-[6-methyl-6-(2H-1,2,3,4-tet...)
Show SMILES CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1
Show InChI InChI=1S/C19H28N4O3/c1-5-14-11-15(13(2)24)16(25)12-17(14)26-10-8-6-7-9-19(3,4)18-20-22-23-21-18/h11-12H,5-10H2,1-4H3,(H2,20,21,22,23,24,25)/p-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
78n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for receptor binding against [3H]-LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assa...


Bioorg Med Chem Lett 2: 1669-1674 (1992)

More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM81519
PNG
(CAS_117690-79-6 | CGS 23356 | CHEMBL15766 | LY 255...)
Show SMILES CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nnn[nH]1
Show InChI InChI=1S/C19H28N4O3/c1-5-14-11-15(13(2)24)16(25)12-17(14)26-10-8-6-7-9-19(3,4)18-20-22-23-21-18/h11-12,25H,5-10H2,1-4H3,(H,20,21,22,23)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
78n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against LTB4 receptor in guinea pig membrane


Bioorg Med Chem Lett 3: 1147-1152 (1993)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50280288
PNG
(4-ethyl-2-isopentyloxy-5-[6-methyl-6-(2H-1,2,3,4-t...)
Show SMILES CCc1cc(OCCC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1
Show InChI InChI=1S/C22H35N4O3/c1-6-17-14-20(29-13-10-16(2)3)18(27)15-19(17)28-12-9-7-8-11-22(4,5)21-23-25-26-24-21/h14-16H,6-13H2,1-5H3,(H-,23,24,25,26,27)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
83n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for receptor binding against [3H]-LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assa...


Bioorg Med Chem Lett 2: 1669-1674 (1992)

More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50280285
PNG
(2-cyclopentyloxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4...)
Show SMILES CCc1cc(OC2CCCC2)c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1
Show InChI InChI=1S/C22H33N4O3/c1-4-16-14-20(29-17-10-6-7-11-17)18(27)15-19(16)28-13-9-5-8-12-22(2,3)21-23-25-26-24-21/h14-15,17H,4-13H2,1-3H3,(H-,23,24,25,26,27)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
109n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for receptor binding against [3H]-LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay


Bioorg Med Chem Lett 2: 1669-1674 (1992)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50280289
PNG
(4-ethyl-2-(4-fluorobenzyloxy)-5-[6-methyl-6-(2H-1,...)
Show SMILES CCc1cc(OCc2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1
Show InChI InChI=1S/C24H30FN4O3/c1-4-18-14-22(32-16-17-8-10-19(25)11-9-17)20(30)15-21(18)31-13-7-5-6-12-24(2,3)23-26-28-29-27-23/h8-11,14-15H,4-7,12-13,16H2,1-3H3,(H-,26,27,28,29,30)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
110n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for receptor binding against [3H]-LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assa...


Bioorg Med Chem Lett 2: 1669-1674 (1992)

More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50280292
PNG
(7-[3-(2-Ethyl-5-hydroxy-4-methoxy-phenoxy)-propoxy...)
Show SMILES CCCc1c(OCCCOc2cc(O)c(OC)cc2CC)ccc2CCC(Oc12)C(O)=O
Show InChI InChI=1S/C25H32O7/c1-4-7-18-20(10-8-17-9-11-21(25(27)28)32-24(17)18)30-12-6-13-31-22-15-19(26)23(29-3)14-16(22)5-2/h8,10,14-15,21,26H,4-7,9,11-13H2,1-3H3,(H,27,28)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 2.90n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay


Bioorg Med Chem Lett 2: 1675-1680 (1992)

More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50280291
PNG
(7-[3-(4-Ethoxy-2-ethyl-5-hydroxy-phenoxy)-propoxy]...)
Show SMILES CCCc1c(OCCCOc2cc(O)c(OCC)cc2CC)ccc2CCC(Oc12)C(O)=O
Show InChI InChI=1S/C26H34O7/c1-4-8-19-21(11-9-18-10-12-22(26(28)29)33-25(18)19)31-13-7-14-32-23-16-20(27)24(30-6-3)15-17(23)5-2/h9,11,15-16,22,27H,4-8,10,12-14H2,1-3H3,(H,28,29)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 4.20n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay


Bioorg Med Chem Lett 2: 1675-1680 (1992)

More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50036750
PNG
(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Show SMILES CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[n-]n2)cc1O
Show InChI InChI=1S/C19H29N4O3/c1-5-14-12-17(25-6-2)15(24)13-16(14)26-11-9-7-8-10-19(3,4)18-20-22-23-21-18/h12-13H,5-11H2,1-4H3,(H-,20,21,22,23,24)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 4.80n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay


Bioorg Med Chem Lett 2: 1675-1680 (1992)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50036750
PNG
(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Show SMILES CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[n-]n2)cc1O
Show InChI InChI=1S/C19H29N4O3/c1-5-14-12-17(25-6-2)15(24)13-16(14)26-11-9-7-8-10-19(3,4)18-20-22-23-21-18/h12-13H,5-11H2,1-4H3,(H-,20,21,22,23,24)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 4.80n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for receptor binding against [3H]-LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay


Bioorg Med Chem Lett 2: 1669-1674 (1992)

More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50280290
PNG
(4-ethyl-2-methoxy-5-[6-methyl-6-(2H-1,2,3,4-tetraa...)
Show SMILES CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1
Show InChI InChI=1S/C18H27N4O3/c1-5-13-11-16(24-4)14(23)12-15(13)25-10-8-6-7-9-18(2,3)17-19-21-22-20-17/h11-12H,5-10H2,1-4H3,(H-,19,20,21,22,23)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for receptor binding against [3H]-LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assa...


Bioorg Med Chem Lett 2: 1669-1674 (1992)

More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50280290
PNG
(4-ethyl-2-methoxy-5-[6-methyl-6-(2H-1,2,3,4-tetraa...)
Show SMILES CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1
Show InChI InChI=1S/C18H27N4O3/c1-5-13-11-16(24-4)14(23)12-15(13)25-10-8-6-7-9-18(2,3)17-19-21-22-20-17/h11-12H,5-10H2,1-4H3,(H-,19,20,21,22,23)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity using [3H]-LTB4 radioligand binding to leukotriene B4 receptor in human neutrophil binding assay


Bioorg Med Chem Lett 2: 1675-1680 (1992)

More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50280286
PNG
(4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraazol-5-yl)h...)
Show SMILES CCCCCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[n-]n2)cc1O
Show InChI InChI=1S/C22H35N4O3/c1-5-7-10-13-29-20-15-17(6-2)19(16-18(20)27)28-14-11-8-9-12-22(3,4)21-23-25-26-24-21/h15-16H,5-14H2,1-4H3,(H-,23,24,25,26,27)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 6.60n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for receptor binding against [3H]-LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assa...


Bioorg Med Chem Lett 2: 1669-1674 (1992)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50280287
PNG
(4-ethyl-2-isopropoxy-5-[6-methyl-6-(2H-1,2,3,4-tet...)
Show SMILES CCc1cc(OC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1
Show InChI InChI=1S/C20H31N4O3/c1-6-15-12-18(27-14(2)3)16(25)13-17(15)26-11-9-7-8-10-20(4,5)19-21-23-24-22-19/h12-14H,6-11H2,1-5H3,(H-,21,22,23,24,25)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 12n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for receptor binding against [3H]-LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay


Bioorg Med Chem Lett 2: 1669-1674 (1992)

More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50281877
PNG
(2-{3-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propo...)
Show SMILES CCCc1c(OCCCOc2cc(O)c(cc2CC)C(C)=O)cccc1OC(C)C(O)=O
Show InChI InChI=1S/C25H32O7/c1-5-9-19-22(10-7-11-23(19)32-17(4)25(28)29)30-12-8-13-31-24-15-21(27)20(16(3)26)14-18(24)6-2/h7,10-11,14-15,17,27H,5-6,8-9,12-13H2,1-4H3,(H,28,29)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 23n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition against LTB4 receptor in human neutrophil


Bioorg Med Chem Lett 3: 1147-1152 (1993)

More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50280289
PNG
(4-ethyl-2-(4-fluorobenzyloxy)-5-[6-methyl-6-(2H-1,...)
Show SMILES CCc1cc(OCc2ccc(F)cc2)c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1
Show InChI InChI=1S/C24H30FN4O3/c1-4-18-14-22(32-16-17-8-10-19(25)11-9-17)20(30)15-21(18)31-13-7-5-6-12-24(2,3)23-26-28-29-27-23/h8-11,14-15H,4-7,12-13,16H2,1-3H3,(H-,26,27,28,29,30)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 31n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for receptor binding against [3H]-LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay


Bioorg Med Chem Lett 2: 1669-1674 (1992)

More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50280288
PNG
(4-ethyl-2-isopentyloxy-5-[6-methyl-6-(2H-1,2,3,4-t...)
Show SMILES CCc1cc(OCCC(C)C)c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1
Show InChI InChI=1S/C22H35N4O3/c1-6-17-14-20(29-13-10-16(2)3)18(27)15-19(17)28-12-9-7-8-11-22(4,5)21-23-25-26-24-21/h14-16H,6-13H2,1-5H3,(H-,23,24,25,26,27)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 36n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for receptor binding against [3H]-LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay


Bioorg Med Chem Lett 2: 1669-1674 (1992)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50281876
PNG
(2-{3-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propo...)
Show SMILES CCCc1c(OCCCOc2cc(O)c(cc2CC)C(C)=O)cccc1OC(CC)C(O)=O
Show InChI InChI=1S/C26H34O7/c1-5-10-19-23(11-8-12-24(19)33-22(7-3)26(29)30)31-13-9-14-32-25-16-21(28)20(17(4)27)15-18(25)6-2/h8,11-12,15-16,22,28H,5-7,9-10,13-14H2,1-4H3,(H,29,30)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 36n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition against LTB4 receptor in human neutrophil


Bioorg Med Chem Lett 3: 1147-1152 (1993)

More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50281873
PNG
(CHEMBL15559 | Sodium; 7-[3-(4-acetyl-2-ethyl-5-hyd...)
Show SMILES CCCc1c(OCCCOc2cc(O)c(cc2CC)C(C)=O)ccc2CCC(Oc12)C([O-])=O
Show InChI InChI=1S/C26H32O7/c1-4-7-19-22(10-8-18-9-11-23(26(29)30)33-25(18)19)31-12-6-13-32-24-15-21(28)20(16(3)27)14-17(24)5-2/h8,10,14-15,23,28H,4-7,9,11-13H2,1-3H3,(H,29,30)/p-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 40n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against LTB4 receptor in guinea pig membrane


Bioorg Med Chem Lett 3: 1147-1152 (1993)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50281874
PNG
(6-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...)
Show SMILES CCCc1cc(OCCCOc2ccc(C(C)=O)c(OC)c2CCC)cc2CCC(Oc12)C(O)=O
Show InChI InChI=1S/C28H36O7/c1-5-8-19-16-21(17-20-10-12-25(28(30)31)35-26(19)20)33-14-7-15-34-24-13-11-22(18(3)29)27(32-4)23(24)9-6-2/h11,13,16-17,25H,5-10,12,14-15H2,1-4H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 41n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition against LTB4 receptor in human neutrophil


Bioorg Med Chem Lett 3: 1147-1152 (1993)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50280285
PNG
(2-cyclopentyloxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4...)
Show SMILES CCc1cc(OC2CCCC2)c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1
Show InChI InChI=1S/C22H33N4O3/c1-4-16-14-20(29-17-10-6-7-11-17)18(27)15-19(16)28-13-9-5-8-12-22(2,3)21-23-25-26-24-21/h14-15,17H,4-13H2,1-3H3,(H-,23,24,25,26,27)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 42n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for receptor binding against [3H]-LTB4 radioligand to Leukotriene B4 receptor in human neutrophil binding assay


Bioorg Med Chem Lett 2: 1669-1674 (1992)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM50281875
PNG
(CHEMBL15648 | {3-[3-(4-Acetyl-2-ethyl-5-hydroxy-ph...)
Show SMILES CCCc1c(OCCCOc2cc(O)c(cc2CC)C(C)=O)cccc1OCC(O)=O
Show InChI InChI=1S/C24H30O7/c1-4-8-18-21(9-6-10-22(18)31-15-24(27)28)29-11-7-12-30-23-14-20(26)19(16(3)25)13-17(23)5-2/h6,9-10,13-14,26H,4-5,7-8,11-12,15H2,1-3H3,(H,27,28)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 67n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition against LTB4 receptor in human neutrophil


Bioorg Med Chem Lett 3: 1147-1152 (1993)

More data for this
Ligand-Target Pair
LTB4R


(HUMAN)
BDBM81519
PNG
(CAS_117690-79-6 | CGS 23356 | CHEMBL15766 | LY 255...)
Show SMILES CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nnn[nH]1
Show InChI InChI=1S/C19H28N4O3/c1-5-14-11-15(13(2)24)16(25)12-17(14)26-10-8-6-7-9-19(3,4)18-20-22-23-21-18/h11-12,25H,5-10H2,1-4H3,(H,20,21,22,23)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 85n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition against LTB4 receptor in human neutrophil


Bioorg Med Chem Lett 3: 1147-1152 (1993)

More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50036749
PNG
(1-{5-ethyl-2-hydroxy-4-[6-methyl-6-(2H-1,2,3,4-tet...)
Show SMILES CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[n-]n1
Show InChI InChI=1S/C19H28N4O3/c1-5-14-11-15(13(2)24)16(25)12-17(14)26-10-8-6-7-9-19(3,4)18-20-22-23-21-18/h11-12H,5-10H2,1-4H3,(H2,20,21,22,23,24,25)/p-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 85n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for receptor binding against [3H]-LTB4 radioligand binding to Leukotriene B4 receptor in guinea pig lung membrane binding assa...


Bioorg Med Chem Lett 2: 1669-1674 (1992)

More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50280291
PNG
(7-[3-(4-Ethoxy-2-ethyl-5-hydroxy-phenoxy)-propoxy]...)
Show SMILES CCCc1c(OCCCOc2cc(O)c(OCC)cc2CC)ccc2CCC(Oc12)C(O)=O
Show InChI InChI=1S/C26H34O7/c1-4-8-19-21(11-9-18-10-12-22(26(28)29)33-25(18)19)31-13-7-14-32-23-16-20(27)24(30-6-3)15-17(23)5-2/h9,11,15-16,22,27H,4-8,10,12-14H2,1-3H3,(H,28,29)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 195n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of LTB4-induced CD11b/CD18 integrin up-regulation in human neutrophils


Bioorg Med Chem Lett 2: 1675-1680 (1992)

More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(HUMAN)
BDBM50036750
PNG
(2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-tetraaz...)
Show SMILES CCOc1cc(CC)c(OCCCCCC(C)(C)c2nn[n-]n2)cc1O
Show InChI InChI=1S/C19H29N4O3/c1-5-14-12-17(25-6-2)15(24)13-16(14)26-11-9-7-8-10-19(3,4)18-20-22-23-21-18/h12-13H,5-11H2,1-4H3,(H-,20,21,22,23,24)/q-1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 206n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of LTB4-induced CD11b/CD18 integrin up-regulation in human neutrophils


Bioorg Med Chem Lett 2: 1675-1680 (1992)

More data for this
Ligand-Target Pair