BindingDB PrimarySearch

Found 5085 hits with Last Name = 'sun' and Initial = 'h'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Coagulation factor XI (Homo sapiens (Human))	BDBM50230326 (CHEMBL4060950) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric method				J Med Chem 60: 1060-1075 (2017) Article DOI: 10.1021/acs.jmedchem.6b01460
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM12659 (1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-5-[...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0900	-56.8	n/a	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Pharmaceutical Research Institute					Assay Description Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...				J Med Chem 48: 1729-44 (2005) Article DOI: 10.1021/jm0497949 BindingDB Entry DOI: 10.7270/Q2BK19K9
Bristol-Myers Squibb Pharmaceutical Research Institute					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM12661 (1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-5-[...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	0.100	-56.5	n/a	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Pharmaceutical Research Institute					Assay Description Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...				J Med Chem 48: 1729-44 (2005) Article DOI: 10.1021/jm0497949 BindingDB Entry DOI: 10.7270/Q2BK19K9
Bristol-Myers Squibb Pharmaceutical Research Institute					More data for this Ligand-Target Pair
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50344100 (2-((2R)-1-((4-methylphenyl)sulfonyl)-3-oxo-2-piper...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human B1 receptor				J Med Chem 54: 7232-46 (2011) Article DOI: 10.1021/jm200808v BindingDB Entry DOI: 10.7270/Q28C9WP1
Amgen Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM12657 (1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2-(methylsul...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.150	-55.5	n/a	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Pharmaceutical Research Institute					Assay Description Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...				J Med Chem 48: 1729-44 (2005) Article DOI: 10.1021/jm0497949 BindingDB Entry DOI: 10.7270/Q2BK19K9
Bristol-Myers Squibb Pharmaceutical Research Institute					More data for this Ligand-Target Pair				3D Structure (crystal)
Coagulation factor X (Homo sapiens (Human))	BDBM12660 (1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-5-[...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	0.160	-55.3	n/a	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Pharmaceutical Research Institute					Assay Description Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...				J Med Chem 48: 1729-44 (2005) Article DOI: 10.1021/jm0497949 BindingDB Entry DOI: 10.7270/Q2BK19K9
Bristol-Myers Squibb Pharmaceutical Research Institute					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM50230322 (CHEMBL4071545) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	0.160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric method				J Med Chem 60: 1060-1075 (2017) Article DOI: 10.1021/acs.jmedchem.6b01460
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Coagulation factor X (Homo sapiens (Human))	BDBM12675 (1-(3-amino-1,2-benzoxazol-5-yl)-N-(2-fluoro-4-{2-[...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	0.170	-55.2	n/a	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Pharmaceutical Research Institute					Assay Description Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...				J Med Chem 48: 1729-44 (2005) Article DOI: 10.1021/jm0497949 BindingDB Entry DOI: 10.7270/Q2BK19K9
Bristol-Myers Squibb Pharmaceutical Research Institute					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM12676 (1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-N-[...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.190	-54.9	n/a	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Pharmaceutical Research Institute					Assay Description Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...				J Med Chem 48: 1729-44 (2005) Article DOI: 10.1021/jm0497949 BindingDB Entry DOI: 10.7270/Q2BK19K9
Bristol-Myers Squibb Pharmaceutical Research Institute					More data for this Ligand-Target Pair				3D Structure (crystal)
Corticotropin releasing factor receptor (Rattus norvegicus (rat)-RAT)	BDBM50219966 (CHEMBL23959) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description In vitro binding affinity to the CRF receptor in rat cortical homogenates				Bioorg Med Chem Lett 13: 125-8 (2003) Article DOI: 10.1016/s0960-894x(02)00833-8
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50203205 ((R)-3-(naphthalene-3-sulfonamido)-3-phenyl-N-((R)-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]DAK from human bradykinin B1 receptor expressed in clone CHO-D-/aequorin cells				Bioorg Med Chem Lett 18: 4764-9 (2008) Article DOI: 10.1016/j.bmcl.2008.07.108 BindingDB Entry DOI: 10.7270/Q29C6X87
Amgen Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3 (IAP1 BIR3) (Homo sapiens (Human))	BDBM50255183 ((1S,3S,6S,10aS)-1-benzyl-6-((S)-2-(methylamino)pro...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of fluorescent SM5F peptide from His-tagged human cIAP2 BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polari...				J Med Chem 52: 593-6 (2009) Article DOI: 10.1021/jm801101z BindingDB Entry DOI: 10.7270/Q2Z03816
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM21397 (8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar	Purchase CHEBI CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of [3H]Spiprone from human dopamine D2 receptor expressed in HEK293 cells				Bioorg Med Chem 20: 4862-71 (2012) Article DOI: 10.1016/j.bmc.2012.05.057 BindingDB Entry DOI: 10.7270/Q28P61K9
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50355063 (CHEMBL1834619) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human B1 receptor				J Med Chem 54: 7232-46 (2011) Article DOI: 10.1021/jm200808v BindingDB Entry DOI: 10.7270/Q28C9WP1
Amgen Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM50136575 (CHEMBL3752610) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 11a assessed as substrate hydrolysis to p-nitroaniline incubated for 10 to 120 mins by spectrophotometry analy...				Bioorg Med Chem Lett 26: 472-8 (2016) Article DOI: 10.1016/j.bmcl.2015.11.089 BindingDB Entry DOI: 10.7270/Q27H1MFM
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human))	BDBM50255183 ((1S,3S,6S,10aS)-1-benzyl-6-((S)-2-(methylamino)pro...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of fluorescent SM5F peptide from His-tagged human cIAP1 BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polari...				J Med Chem 52: 593-6 (2009) Article DOI: 10.1021/jm801101z BindingDB Entry DOI: 10.7270/Q2Z03816
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM12677 (1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-N-[...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	0.370	-53.3	n/a	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Pharmaceutical Research Institute					Assay Description Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...				J Med Chem 48: 1729-44 (2005) Article DOI: 10.1021/jm0497949 BindingDB Entry DOI: 10.7270/Q2BK19K9
Bristol-Myers Squibb Pharmaceutical Research Institute					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor (Rattus norvegicus (rat)-RAT)	BDBM50219965 (CHEMBL430913) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description In vitro binding affinity to the CRF receptor in rat cortical homogenates				Bioorg Med Chem Lett 13: 125-8 (2003) Article DOI: 10.1016/s0960-894x(02)00833-8
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human))	BDBM50393632 (CHEMBL2158601) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to BIR3 domain of cIAP1 by fluorescence polarization assay				J Med Chem 55: 106-14 (2012) Article DOI: 10.1021/jm201072x BindingDB Entry DOI: 10.7270/Q2BG2Q3B
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50209744 ((R)-3-(4-fluorophenyl)-N-((R)-7-(piperidin-1-ylmet...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cells				J Med Chem 50: 2200-12 (2007) Article DOI: 10.1021/jm070055c BindingDB Entry DOI: 10.7270/Q2MS3SG2
Amgen Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A) (Homo sapiens (Human))	BDBM22867 (1,1-diethyl-3-[(8beta)-6-methyl-9,10-didehydroergo...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	0.410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Canterbury Curated by PDSP K_i Database									Biochem Pharmacol 45: 1003-9 (1993) Article DOI: 10.1016/0006-2952(93)90243-p BindingDB Entry DOI: 10.7270/Q2JH3JPG
University of Canterbury Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM50230325 (CHEMBL4062923) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric method				J Med Chem 60: 1060-1075 (2017) Article DOI: 10.1021/acs.jmedchem.6b01460
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM21397 (8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar	Purchase CHEBI CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	0.5	-54.0	2.56	n/a	n/a	n/a	n/a	n/a	30
SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES US Patent					Assay Description Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...				US Patent US9359372 (2016) BindingDB Entry DOI: 10.7270/Q2736PSP
					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human))	BDBM50343522 ((S,3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-(1,1'-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to BIR3 domain of cIAP1 by fluorescence polarization assay				J Med Chem 55: 106-14 (2012) Article DOI: 10.1021/jm201072x BindingDB Entry DOI: 10.7270/Q2BG2Q3B
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor (Rattus norvegicus (rat)-RAT)	BDBM50220479 (CHEMBL23342) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description In vitro binding affinity to the CRF receptor in rat cortical homogenates				Bioorg Med Chem Lett 13: 125-8 (2003) Article DOI: 10.1016/s0960-894x(02)00833-8
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM12662 (1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-5-[...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	0.510	-52.5	n/a	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Pharmaceutical Research Institute					Assay Description Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...				J Med Chem 48: 1729-44 (2005) Article DOI: 10.1021/jm0497949 BindingDB Entry DOI: 10.7270/Q2BK19K9
Bristol-Myers Squibb Pharmaceutical Research Institute					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM12666 (1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-5-[...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	0.520	-52.5	n/a	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Pharmaceutical Research Institute					Assay Description Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...				J Med Chem 48: 1729-44 (2005) Article DOI: 10.1021/jm0497949 BindingDB Entry DOI: 10.7270/Q2BK19K9
Bristol-Myers Squibb Pharmaceutical Research Institute					More data for this Ligand-Target Pair
Adenosine receptor A2 (Homo sapiens (Human))	BDBM50018688 (CHEMBL3291301) Show SMILES CCCCCCC#Cc1nc(N)c2nc(Br)n(CC#C)c2n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yamasa Corporation Curated by ChEMBL					Assay Description Displacement of [3H]-CGS-21680 from human adenosine A2A receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem 22: 3072-82 (2014) Article DOI: 10.1016/j.bmc.2014.04.041 BindingDB Entry DOI: 10.7270/Q2348MXH
Yamasa Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor (Rattus norvegicus (rat)-RAT)	BDBM50220478 (CHEMBL22622) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description In vitro binding affinity to the CRF receptor in rat cortical homogenates				Bioorg Med Chem Lett 13: 125-8 (2003) Article DOI: 10.1016/s0960-894x(02)00833-8
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50355062 (CHEMBL1834752) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human B1 receptor				J Med Chem 54: 7232-46 (2011) Article DOI: 10.1021/jm200808v BindingDB Entry DOI: 10.7270/Q28C9WP1
Amgen Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50355057 (CHEMBL1834751) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human B1 receptor				J Med Chem 54: 7232-46 (2011) Article DOI: 10.1021/jm200808v BindingDB Entry DOI: 10.7270/Q28C9WP1
Amgen Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor (Rattus norvegicus (rat)-RAT)	BDBM50219957 (CHEMBL3085294) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description In vitro binding affinity to the CRF receptor in rat cortical homogenates				Bioorg Med Chem Lett 13: 125-8 (2003) Article DOI: 10.1016/s0960-894x(02)00833-8
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM12667 (1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-5-[...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	0.600	-52.1	n/a	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Pharmaceutical Research Institute					Assay Description Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...				J Med Chem 48: 1729-44 (2005) Article DOI: 10.1021/jm0497949 BindingDB Entry DOI: 10.7270/Q2BK19K9
Bristol-Myers Squibb Pharmaceutical Research Institute					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A) (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	0.620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells				Bioorg Med Chem 20: 4862-71 (2012) Article DOI: 10.1016/j.bmc.2012.05.057 BindingDB Entry DOI: 10.7270/Q28P61K9
Shenyang Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human))	BDBM26223 ((3S,6S,10aS)-6-[(2S)-2-(methylamino)propanamido]-5...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of fluorescent SM5F peptide from His-tagged human cIAP1 BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polari...				J Med Chem 52: 593-6 (2009) Article DOI: 10.1021/jm801101z BindingDB Entry DOI: 10.7270/Q2Z03816
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human))	BDBM50393631 (CHEMBL2158600) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to BIR3 domain of cIAP1 by fluorescence polarization assay				J Med Chem 55: 106-14 (2012) Article DOI: 10.1021/jm201072x BindingDB Entry DOI: 10.7270/Q2BG2Q3B
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50203200 ((R)-3-(naphthalene-7-sulfonamido)-3-phenyl-N-((R)-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cells				J Med Chem 50: 2200-12 (2007) Article DOI: 10.1021/jm070055c BindingDB Entry DOI: 10.7270/Q2MS3SG2
Amgen Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor (Rattus norvegicus (rat)-RAT)	BDBM50219962 (CHEMBL431105) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description In vitro binding affinity against Corticotropin releasing factor receptor in rat cortical homogenates				Bioorg Med Chem Lett 13: 125-8 (2003) Article DOI: 10.1016/s0960-894x(02)00833-8
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
X-linked inhibitor of apoptosis protein (XIAP) (Homo sapiens (Human))	BDBM50432760 (CHEMBL2348620) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to XIAP linker BIR2-BIR3 domain (unknown origin) after 3 hrs by competitive fluorescence polarization assay in presence of Smac-1F				J Med Chem 56: 3969-79 (2013) Article DOI: 10.1021/jm400216d BindingDB Entry DOI: 10.7270/Q2M61MNM
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50143028 (8'N-[1-[1-carbamoyl-3-phenyl-(1S)-propylcarbamoyl]...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro binding affinity towards human motilin receptor				J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor (Rattus norvegicus (rat)-RAT)	BDBM50219954 (CHEMBL283993) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description In vitro binding affinity against Corticotropin releasing factor receptor in rat cortical homogenates				Bioorg Med Chem Lett 13: 125-8 (2003) Article DOI: 10.1016/s0960-894x(02)00833-8
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor (Rattus norvegicus (rat)-RAT)	BDBM50219969 (CHEMBL23439) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description In vitro binding affinity to the CRF receptor in rat cortical homogenates				Bioorg Med Chem Lett 13: 125-8 (2003) Article DOI: 10.1016/s0960-894x(02)00833-8
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM12663 (1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-5-[...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	0.700	-51.7	n/a	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Pharmaceutical Research Institute					Assay Description Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...				J Med Chem 48: 1729-44 (2005) Article DOI: 10.1021/jm0497949 BindingDB Entry DOI: 10.7270/Q2BK19K9
Bristol-Myers Squibb Pharmaceutical Research Institute					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM12671 (1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-5-[...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	0.730	-51.6	n/a	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Pharmaceutical Research Institute					Assay Description Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...				J Med Chem 48: 1729-44 (2005) Article DOI: 10.1021/jm0497949 BindingDB Entry DOI: 10.7270/Q2BK19K9
Bristol-Myers Squibb Pharmaceutical Research Institute					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor (Rattus norvegicus (rat)-RAT)	BDBM50219962 (CHEMBL431105) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description In vitro binding affinity to the CRF receptor in rat cortical homogenates				Bioorg Med Chem Lett 13: 125-8 (2003) Article DOI: 10.1016/s0960-894x(02)00833-8
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor (Rattus norvegicus (rat)-RAT)	BDBM50220480 (CHEMBL22433) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description In vitro binding affinity to the CRF receptor in rat cortical homogenates				Bioorg Med Chem Lett 13: 125-8 (2003) Article DOI: 10.1016/s0960-894x(02)00833-8
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human))	BDBM26218 ((3S,6S,10aS)-N-(diphenylmethyl)-6-[(2S)-2-(methyla...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of fluorescent SM5F peptide from His-tagged human cIAP1 BIR3 domain expressed in Escherichia coli BL21(DE3) cells by fluorescence polari...				J Med Chem 52: 593-6 (2009) Article DOI: 10.1021/jm801101z BindingDB Entry DOI: 10.7270/Q2Z03816
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM50230340 (CHEMBL4087980) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric method				J Med Chem 60: 1060-1075 (2017) Article DOI: 10.1021/acs.jmedchem.6b01460
Bristol-Myers Squibb Company Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A) (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5-HT1A receptor (unknown origin) expressed in HEK293 cells by liquid scintillation counter				Bioorg Med Chem 21: 856-68 (2013) Article DOI: 10.1016/j.bmc.2012.12.016 BindingDB Entry DOI: 10.7270/Q2JD4Z4M
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50355064 (CHEMBL1834616) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human B1 receptor				J Med Chem 54: 7232-46 (2011) Article DOI: 10.1021/jm200808v BindingDB Entry DOI: 10.7270/Q28C9WP1
Amgen Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

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