Found 398 hits with Last Name = 'zhong' and Initial = 'h' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354066
(CHEMBL1836324)Show InChI InChI=1S/C18H25N3O2S3/c1-2-26(22,23)20-12-7-3-6-11-19-18-21-17-14-8-4-5-9-15(14)24-13-10-16(17)25-18/h4-5,8-9,20H,2-3,6-7,10-13H2,1H3,(H,19,21) | Reactome pathway
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PC sid
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| Article
PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354068
(CHEMBL1836322)Show SMILES CCS(=O)(=O)NCCCCCNc1nc-2c(CCCc3ccc(F)cc-23)s1 Show InChI InChI=1S/C19H26FN3O2S2/c1-2-27(24,25)22-12-5-3-4-11-21-19-23-18-16-13-15(20)10-9-14(16)7-6-8-17(18)26-19/h9-10,13,22H,2-8,11-12H2,1H3,(H,21,23) | Reactome pathway
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PubMed
| 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354079
(CHEMBL1836329)Show SMILES COc1cccc2-c3nc(N[C@H]4CC[C@H](CNS(C)(=O)=O)CC4)sc3CCOc12 Show InChI InChI=1S/C20H27N3O4S2/c1-26-16-5-3-4-15-18-17(10-11-27-19(15)16)28-20(23-18)22-14-8-6-13(7-9-14)12-21-29(2,24)25/h3-5,13-14,21H,6-12H2,1-2H3,(H,22,23)/t13-,14- | Reactome pathway
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| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354077
(CHEMBL1836331)Show SMILES CS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc-2c(CCCc3ccc(F)cc-23)s1 Show InChI InChI=1S/C20H26FN3O2S2/c1-28(25,26)22-12-13-5-9-16(10-6-13)23-20-24-19-17-11-15(21)8-7-14(17)3-2-4-18(19)27-20/h7-8,11,13,16,22H,2-6,9-10,12H2,1H3,(H,23,24)/t13-,16- | Reactome pathway
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| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
NPY5R
(Rat 6B) | BDBM50354072
(CHEMBL1836317)Show SMILES CS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc-2c(CCSc3ccccc-23)s1 Show InChI InChI=1S/C19H25N3O2S3/c1-27(23,24)20-12-13-6-8-14(9-7-13)21-19-22-18-15-4-2-3-5-16(15)25-11-10-17(18)26-19/h2-5,13-14,20H,6-12H2,1H3,(H,21,22)/t13-,14- | Reactome pathway
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| Article
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| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at rat NPY5 receptor |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354083
(CHEMBL1836102 | N-{[(1r,4r)-4-{[(4-aminoquinazolin...)Show SMILES Nc1nc(NC[C@H]2CC[C@H](CNS(=O)(=O)c3ccc4ccccc4c3)CC2)nc2ccccc12 Show InChI InChI=1S/C26H29N5O2S/c27-25-23-7-3-4-8-24(23)30-26(31-25)28-16-18-9-11-19(12-10-18)17-29-34(32,33)22-14-13-20-5-1-2-6-21(20)15-22/h1-8,13-15,18-19,29H,9-12,16-17H2,(H3,27,28,30,31)/t18-,19- | Reactome pathway
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| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to NPY5 receptor |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354070
(CHEMBL1836319)Show SMILES CS(=O)(=O)NCCCCCNc1nc-2c(CCCc3ccc(F)cc-23)s1 Show InChI InChI=1S/C18H24FN3O2S2/c1-26(23,24)21-11-4-2-3-10-20-18-22-17-15-12-14(19)9-8-13(15)6-5-7-16(17)25-18/h8-9,12,21H,2-7,10-11H2,1H3,(H,20,22) | Reactome pathway
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| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354072
(CHEMBL1836317)Show SMILES CS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc-2c(CCSc3ccccc-23)s1 Show InChI InChI=1S/C19H25N3O2S3/c1-27(23,24)20-12-13-6-8-14(9-7-13)21-19-22-18-15-4-2-3-5-16(15)25-11-10-17(18)26-19/h2-5,13-14,20H,6-12H2,1H3,(H,21,22)/t13-,14- | Reactome pathway
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| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50400902
(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)Show InChI InChI=1S/C18H22N2S/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3 | PDB
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| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Binding affinity to human SERT |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354078
(CHEMBL1836330)Show SMILES CS(=O)(=O)NCCCCCNc1nc-2c(CCSc3ccc(F)cc-23)s1 Show InChI InChI=1S/C17H22FN3O2S3/c1-26(22,23)20-9-4-2-3-8-19-17-21-16-13-11-12(18)5-6-14(13)24-10-7-15(16)25-17/h5-6,11,20H,2-4,7-10H2,1H3,(H,19,21) | Reactome pathway
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| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354073
(CHEMBL1836316)Show SMILES O=S(=O)(NC[C@H]1CC[C@@H](CC1)Nc1nc-2c(CCSc3ccccc-23)s1)c1cccs1 Show InChI InChI=1S/C22H25N3O2S4/c26-31(27,20-6-3-12-29-20)23-14-15-7-9-16(10-8-15)24-22-25-21-17-4-1-2-5-18(17)28-13-11-19(21)30-22/h1-6,12,15-16,23H,7-11,13-14H2,(H,24,25)/t15-,16- | Reactome pathway
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| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354081
(CHEMBL1836327)Show SMILES CC(C)S(=O)(=O)NCCOCCNc1nc-2c(CCCc3ccc(F)cc-23)s1 Show InChI InChI=1S/C19H26FN3O3S2/c1-13(2)28(24,25)22-9-11-26-10-8-21-19-23-18-16-12-15(20)7-6-14(16)4-3-5-17(18)27-19/h6-7,12-13,22H,3-5,8-11H2,1-2H3,(H,21,23) | Reactome pathway
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| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354071
(CHEMBL1836318)Show SMILES CCS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc-2c(CCSc3ccccc-23)s1 Show InChI InChI=1S/C20H27N3O2S3/c1-2-28(24,25)21-13-14-7-9-15(10-8-14)22-20-23-19-16-5-3-4-6-17(16)26-12-11-18(19)27-20/h3-6,14-15,21H,2,7-13H2,1H3,(H,22,23)/t14-,15- | Reactome pathway
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| 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM85330
(CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...)Show InChI InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3 | PDB
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Article
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| 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354064
(CHEMBL1836326)Show SMILES Fc1ccc2CCCc3sc(NCCCCNS(=O)(=O)CC(F)(F)F)nc3-c2c1 Show InChI InChI=1S/C18H21F4N3O2S2/c19-13-7-6-12-4-3-5-15-16(14(12)10-13)25-17(28-15)23-8-1-2-9-24-29(26,27)11-18(20,21)22/h6-7,10,24H,1-5,8-9,11H2,(H,23,25) | Reactome pathway
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| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50400902
(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)Show InChI InChI=1S/C18H22N2S/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3 | PDB
Reactome pathway
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| 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT3A receptor |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354076
(CHEMBL1836103)Show SMILES COc1ccc(C)cc1S(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc-2c(CCSc3ccccc-23)s1 Show InChI InChI=1S/C26H31N3O3S3/c1-17-7-12-21(32-2)24(15-17)35(30,31)27-16-18-8-10-19(11-9-18)28-26-29-25-20-5-3-4-6-22(20)33-14-13-23(25)34-26/h3-7,12,15,18-19,27H,8-11,13-14,16H2,1-2H3,(H,28,29)/t18-,19- | Reactome pathway
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| 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50354083
(CHEMBL1836102 | N-{[(1r,4r)-4-{[(4-aminoquinazolin...)Show SMILES Nc1nc(NC[C@H]2CC[C@H](CNS(=O)(=O)c3ccc4ccccc4c3)CC2)nc2ccccc12 Show InChI InChI=1S/C26H29N5O2S/c27-25-23-7-3-4-8-24(23)30-26(31-25)28-16-18-9-11-19(12-10-18)17-29-34(32,33)22-14-13-20-5-1-2-6-21(20)15-22/h1-8,13-15,18-19,29H,9-12,16-17H2,(H3,27,28,30,31)/t18-,19- | PDB
Reactome pathway
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| 6.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of serotonin transporter |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354080
(CHEMBL1836328)Show SMILES COc1ccc2-c3nc(NC[C@H]4CC[C@@H](CC4)NS(C)(=O)=O)sc3CCOc2c1 Show InChI InChI=1S/C20H27N3O4S2/c1-26-15-7-8-16-17(11-15)27-10-9-18-19(16)22-20(28-18)21-12-13-3-5-14(6-4-13)23-29(2,24)25/h7-8,11,13-14,23H,3-6,9-10,12H2,1-2H3,(H,21,22)/t13-,14- | Reactome pathway
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PubMed
| 6.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50400899
(CHEMBL2204363)Show InChI InChI=1S/C17H19ClN2S/c1-13-6-7-16(14(18)12-13)21-17-5-3-2-4-15(17)20-10-8-19-9-11-20/h2-7,12,19H,8-11H2,1H3 | PDB
Reactome pathway
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| 7.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354082
(CHEMBL1836321)Show SMILES Fc1ccc2CCCc3sc(NCCCCCNS(=O)(=O)CC(F)(F)F)nc3-c2c1 Show InChI InChI=1S/C19H23F4N3O2S2/c20-14-8-7-13-5-4-6-16-17(15(13)11-14)26-18(29-16)24-9-2-1-3-10-25-30(27,28)12-19(21,22)23/h7-8,11,25H,1-6,9-10,12H2,(H,24,26) | Reactome pathway
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| 7.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354067
(CHEMBL1836323)Show InChI InChI=1S/C17H23N3O2S3/c1-25(21,22)19-11-6-2-5-10-18-17-20-16-13-7-3-4-8-14(13)23-12-9-15(16)24-17/h3-4,7-8,19H,2,5-6,9-12H2,1H3,(H,18,20) | Reactome pathway
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| 8.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50174316
(CHEMBL3809355)Show InChI InChI=1S/C21H34O2/c1-4-5-6-10-13-21(2,3)17-14-18(22)20(19(23)15-17)16-11-8-7-9-12-16/h14-16,22-23H,4-13H2,1-3H3 | PDB
NCI pathway
Reactome pathway
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| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
KannaLife Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP 55940 from human CB1 receptor after 1 hr by liquid scintillation spectrometry |
ACS Med Chem Lett 7: 424-8 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00009
BindingDB Entry DOI: 10.7270/Q2BZ680Z |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50400901
(CHEMBL2204361)Show InChI InChI=1S/C17H19ClN2OS/c1-21-13-6-7-16(14(18)12-13)22-17-5-3-2-4-15(17)20-10-8-19-9-11-20/h2-7,12,19H,8-11H2,1H3 | PDB
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| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354075
(CHEMBL1836314)Show SMILES O=S(=O)(NC[C@H]1CC[C@@H](CC1)Nc1nc-2c(CCSc3ccccc-23)s1)c1cccc2ccccc12 Show InChI InChI=1S/C28H29N3O2S3/c32-36(33,26-11-5-7-20-6-1-2-8-22(20)26)29-18-19-12-14-21(15-13-19)30-28-31-27-23-9-3-4-10-24(23)34-17-16-25(27)35-28/h1-11,19,21,29H,12-18H2,(H,30,31)/t19-,21- | Reactome pathway
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| 13.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50400895
(CHEMBL2205051)Show InChI InChI=1S/C17H20N2S/c1-14-6-2-4-8-16(14)20-17-9-5-3-7-15(17)19-12-10-18-11-13-19/h2-9,18H,10-13H2,1H3 | Reactome pathway
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| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]5-carboxamidotryptamine to human 5HT1A expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50400902
(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)Show InChI InChI=1S/C18H22N2S/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3 | Reactome pathway
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| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1A receptor |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354063
(CHEMBL1836332)Show SMILES CS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc-2c(CCOc3ccccc-23)s1 Show InChI InChI=1S/C19H25N3O3S2/c1-27(23,24)20-12-13-6-8-14(9-7-13)21-19-22-18-15-4-2-3-5-16(15)25-11-10-17(18)26-19/h2-5,13-14,20H,6-12H2,1H3,(H,21,22)/t13-,14- | Reactome pathway
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| 16.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50400900
(CHEMBL2204362)Show InChI InChI=1S/C18H22N2OS/c1-14-7-8-18(16(13-14)21-2)22-17-6-4-3-5-15(17)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3 | PDB
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| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50400902
(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)Show InChI InChI=1S/C18H22N2S/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3 | Reactome pathway
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| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT7 receptor |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50001859
((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 | Reactome pathway
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| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]5-carboxamidotryptamine to human 5HT1A expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354074
(CHEMBL1836315)Show SMILES Cn1cnc(c1)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc-2c(CCSc3ccccc-23)s1 Show InChI InChI=1S/C22H27N5O2S3/c1-27-13-20(23-14-27)32(28,29)24-12-15-6-8-16(9-7-15)25-22-26-21-17-4-2-3-5-18(17)30-11-10-19(21)31-22/h2-5,13-16,24H,6-12H2,1H3,(H,25,26)/t15-,16- | Reactome pathway
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| 21.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50400902
(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)Show InChI InChI=1S/C18H22N2S/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3 | PDB
Reactome pathway
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| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50400903
(CHEMBL2204359)Show InChI InChI=1S/C16H16Cl2N2S/c17-12-5-6-15(13(18)11-12)21-16-4-2-1-3-14(16)20-9-7-19-8-10-20/h1-6,11,19H,7-10H2 | PDB
Reactome pathway
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| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50354065
(CHEMBL1836325)Show SMILES CS(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1nc-2c(CCCc3ccc(F)cc-23)s1 Show InChI InChI=1S/C19H24FN3O2S2/c1-27(24,25)23-15-9-7-14(8-10-15)21-19-22-18-16-11-13(20)6-5-12(16)3-2-4-17(18)26-19/h5-6,11,14-15,23H,2-4,7-10H2,1H3,(H,21,22)/t14-,15- | Reactome pathway
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| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human NPY5 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50400906
(CHEMBL2205034)Show InChI InChI=1S/C19H24N2S/c1-15-8-9-18(16(2)14-15)22-19-7-4-3-6-17(19)21-12-5-10-20-11-13-21/h3-4,6-9,14,20H,5,10-13H2,1-2H3 | PDB
Reactome pathway
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| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50400889
(CHEMBL2204357)Show InChI InChI=1S/C18H22N2S/c1-14-6-5-9-17(15(14)2)21-18-8-4-3-7-16(18)20-12-10-19-11-13-20/h3-9,19H,10-13H2,1-2H3 | PDB
Reactome pathway
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| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50400884
(CHEMBL2205041)Show InChI InChI=1S/C16H18N2S/c1-2-6-14(7-3-1)19-16-9-5-4-8-15(16)18-12-10-17-11-13-18/h1-9,17H,10-13H2 | Reactome pathway
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| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]5-carboxamidotryptamine to human 5HT1A expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50400889
(CHEMBL2204357)Show InChI InChI=1S/C18H22N2S/c1-14-6-5-9-17(15(14)2)21-18-8-4-3-7-16(18)20-12-10-19-11-13-20/h3-9,19H,10-13H2,1-2H3 | Reactome pathway
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| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]5-carboxamidotryptamine to human 5HT1A expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50400895
(CHEMBL2205051)Show InChI InChI=1S/C17H20N2S/c1-14-6-2-4-8-16(14)20-17-9-5-3-7-15(17)19-12-10-18-11-13-19/h2-9,18H,10-13H2,1H3 | PDB
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| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5 ( NPY Y5)
(Homo sapiens (Human)) | BDBM50089046
(CHEMBL17022 | Naphthalene-2-sulfonic acid (4-{[(na...)Show SMILES O=S(=O)(NC[C@H]1CC[C@H](CNCc2ccc3ccccc3c2)CC1)c1ccc2ccccc2c1 Show InChI InChI=1S/C29H32N2O2S/c32-34(33,29-16-15-26-6-2-4-8-28(26)18-29)31-21-23-11-9-22(10-12-23)19-30-20-24-13-14-25-5-1-3-7-27(25)17-24/h1-8,13-18,22-23,30-31H,9-12,19-21H2/t22-,23- | Reactome pathway
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| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to NPY5 receptor |
Bioorg Med Chem Lett 21: 5436-41 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.124
BindingDB Entry DOI: 10.7270/Q2RN387K |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50400904
(CHEMBL2204358)Show InChI InChI=1S/C18H22N2O2S/c1-21-14-7-8-18(16(13-14)22-2)23-17-6-4-3-5-15(17)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50400902
(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)Show InChI InChI=1S/C18H22N2S/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Binding affinity at human 5HT1B receptor |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50400892
(CHEMBL2205054)Show InChI InChI=1S/C18H22N2S/c1-14-7-8-16(13-15(14)2)21-18-6-4-3-5-17(18)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50092588
(4-(1,1-Dimethyl-heptyl)-2'-isopropyl-5'-methyl-bip...)Show SMILES CCCCCCC(C)(C)c1ccc(c(O)c1)-c1cc(C)ccc1C(C)C Show InChI InChI=1S/C25H36O/c1-7-8-9-10-15-25(5,6)20-12-14-22(24(26)17-20)23-16-19(4)11-13-21(23)18(2)3/h11-14,16-18,26H,7-10,15H2,1-6H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
KannaLife Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP 55940 from human CB1 receptor after 1 hr by liquid scintillation spectrometry |
ACS Med Chem Lett 7: 424-8 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00009
BindingDB Entry DOI: 10.7270/Q2BZ680Z |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50400883
(CHEMBL2205042)Show InChI InChI=1S/C17H20N2OS/c1-20-14-6-8-15(9-7-14)21-17-5-3-2-4-16(17)19-12-10-18-11-13-19/h2-9,18H,10-13H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50400882
(CHEMBL2205043)Show InChI InChI=1S/C16H17ClN2S/c17-13-5-7-14(8-6-13)20-16-4-2-1-3-15(16)19-11-9-18-10-12-19/h1-8,18H,9-12H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50400902
(1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine...)Show InChI InChI=1S/C18H22N2S/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3 | Reactome pathway
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]5-carboxamidotryptamine to human 5HT1A expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50400881
(CHEMBL2205044)Show InChI InChI=1S/C16H17FN2S/c17-13-5-7-14(8-6-13)20-16-4-2-1-3-15(16)19-11-9-18-10-12-19/h1-8,18H,9-12H2 | Reactome pathway
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]5-carboxamidotryptamine to human 5HT1A expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50400880
(CHEMBL2205045)Show InChI InChI=1S/C17H20N2S/c1-14-6-8-15(9-7-14)20-17-5-3-2-4-16(17)19-12-10-18-11-13-19/h2-9,18H,10-13H2,1H3 | Reactome pathway
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S
Curated by ChEMBL
| Assay Description
Displacement of [3H]5-carboxamidotryptamine to human 5HT1A expressed in HEK293 cells by filter binding assay |
J Med Chem 54: 3206-21 (2011)
Article DOI: 10.1021/jm101459g
BindingDB Entry DOI: 10.7270/Q2W37XFC |
More data for this
Ligand-Target Pair | |
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