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Compile Data Set for Download or QSAR

Found 1444 hits with Last Name = 'zorn' and Initial = 'l'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300589
PNG
(4-(cyclopropyloxy)-3-({[1-(morpholin-4-yl)cyclopro...)
Show SMILES O=C(Nc1nnc(s1)-c1ccccc1)c1ccc(OC2CC2)c(NC(=O)C2(CC2)N2CCOCC2)c1
Show InChI InChI=1S/C26H27N5O4S/c32-22(28-25-30-29-23(36-25)17-4-2-1-3-5-17)18-6-9-21(35-19-7-8-19)20(16-18)27-24(33)26(10-11-26)31-12-14-34-15-13-31/h1-6,9,16,19H,7-8,10-15H2,(H,27,33)(H,28,30,32)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300592
PNG
(3-({[(2S)-2,4-dimethylpiperazin-1-yl]acetyl}amino)...)
Show SMILES C[C@H]1CN(C)CCN1CC(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccccc1F
Show InChI InChI=1S/C27H27F4N5O3/c1-17-15-35(2)11-12-36(17)16-25(37)34-23-13-18(7-10-24(23)39-27(29,30)31)26(38)33-19-8-9-22(32-14-19)20-5-3-4-6-21(20)28/h3-10,13-14,17H,11-12,15-16H2,1-2H3,(H,33,38)(H,34,37)/t17-/m0/s1
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300593
PNG
(3-({[(3S)-3,4-dimethylpiperazin-1-yl]acetyl}amino)...)
Show SMILES C[C@H]1CN(CC(=O)Nc2cc(ccc2OC(F)(F)F)C(=O)Nc2ccc(nc2)-c2ccccc2F)CCN1C
Show InChI InChI=1S/C27H27F4N5O3/c1-17-15-36(12-11-35(17)2)16-25(37)34-23-13-18(7-10-24(23)39-27(29,30)31)26(38)33-19-8-9-22(32-14-19)20-5-3-4-6-21(20)28/h3-10,13-14,17H,11-12,15-16H2,1-2H3,(H,33,38)(H,34,37)/t17-/m0/s1
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300594
PNG
(3-({[(3R)-3,4-dimethylpiperazin-1-yl]acetyl}amino)...)
Show SMILES C[C@@H]1CN(CC(=O)Nc2cc(ccc2OC(F)(F)F)C(=O)Nc2ccc(nc2)-c2ccccc2F)CCN1C
Show InChI InChI=1S/C27H27F4N5O3/c1-17-15-36(12-11-35(17)2)16-25(37)34-23-13-18(7-10-24(23)39-27(29,30)31)26(38)33-19-8-9-22(32-14-19)20-5-3-4-6-21(20)28/h3-10,13-14,17H,11-12,15-16H2,1-2H3,(H,33,38)(H,34,37)/t17-/m1/s1
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300597
PNG
(3-{[(2,4-dimethylpiperazin-1-yl)acetyl]amino}-N-(5...)
Show SMILES CC1CN(C)CCN1CC(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1nnc(s1)-c1ccccc1
Show InChI InChI=1S/C24H25F3N6O3S/c1-15-13-32(2)10-11-33(15)14-20(34)28-18-12-17(8-9-19(18)36-24(25,26)27)21(35)29-23-31-30-22(37-23)16-6-4-3-5-7-16/h3-9,12,15H,10-11,13-14H2,1-2H3,(H,28,34)(H,29,31,35)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300599
PNG
(3-[(1,4-oxazepan-4-ylacetyl)amino]-N-(5-phenyl-1,3...)
Show SMILES FC(F)(F)Oc1ccc(cc1NC(=O)CN1CCCOCC1)C(=O)Nc1nnc(s1)-c1ccccc1
Show InChI InChI=1S/C23H22F3N5O4S/c24-23(25,26)35-18-8-7-16(13-17(18)27-19(32)14-31-9-4-11-34-12-10-31)20(33)28-22-30-29-21(36-22)15-5-2-1-3-6-15/h1-3,5-8,13H,4,9-12,14H2,(H,27,32)(H,28,30,33)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300600
PNG
(4-(cyclopropyloxy)-3-[(morpholin-4-ylacetyl)amino]...)
Show SMILES O=C(CN1CCOCC1)Nc1cc(ccc1OC1CC1)C(=O)Nc1nnc(s1)-c1ccccc1
Show InChI InChI=1S/C24H25N5O4S/c30-21(15-29-10-12-32-13-11-29)25-19-14-17(6-9-20(19)33-18-7-8-18)22(31)26-24-28-27-23(34-24)16-4-2-1-3-5-16/h1-6,9,14,18H,7-8,10-13,15H2,(H,25,30)(H,26,28,31)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300601
PNG
(4-(cyclopropyloxy)-3-({[1-(4-methylpiperazin-1-yl)...)
Show SMILES CN1CCN(CC1)C1(CC1)C(=O)Nc1cc(ccc1OC1CC1)C(=O)Nc1nnc(s1)-c1ccccc1
Show InChI InChI=1S/C27H30N6O3S/c1-32-13-15-33(16-14-32)27(11-12-27)25(35)28-21-17-19(7-10-22(21)36-20-8-9-20)23(34)29-26-31-30-24(37-26)18-5-3-2-4-6-18/h2-7,10,17,20H,8-9,11-16H2,1H3,(H,28,35)(H,29,31,34)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300602
PNG
(3-{[(4-ethylpiperazin-1-yl)acetyl]amino}-N-(5-phen...)
Show SMILES CCN1CCN(CC(=O)Nc2cc(ccc2OC(F)(F)F)C(=O)Nc2nnc(s2)-c2ccccc2)CC1
Show InChI InChI=1S/C24H25F3N6O3S/c1-2-32-10-12-33(13-11-32)15-20(34)28-18-14-17(8-9-19(18)36-24(25,26)27)21(35)29-23-31-30-22(37-23)16-6-4-3-5-7-16/h3-9,14H,2,10-13,15H2,1H3,(H,28,34)(H,29,31,35)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300603
PNG
(4-chloro-3-{[(4-methylpiperazin-1-yl)acetyl]amino}...)
Show SMILES CN1CCN(CC(=O)Nc2cc(ccc2Cl)C(=O)Nc2nnc(s2)-c2ccccc2)CC1
Show InChI InChI=1S/C22H23ClN6O2S/c1-28-9-11-29(12-10-28)14-19(30)24-18-13-16(7-8-17(18)23)20(31)25-22-27-26-21(32-22)15-5-3-2-4-6-15/h2-8,13H,9-12,14H2,1H3,(H,24,30)(H,25,27,31)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300604
PNG
(4-cyano-3-{[(4-methylpiperazin-1-yl)acetyl]amino}-...)
Show SMILES CN1CCN(CC(=O)Nc2cc(ccc2C#N)C(=O)Nc2nnc(s2)-c2ccccc2)CC1
Show InChI InChI=1S/C23H23N7O2S/c1-29-9-11-30(12-10-29)15-20(31)25-19-13-17(7-8-18(19)14-24)21(32)26-23-28-27-22(33-23)16-5-3-2-4-6-16/h2-8,13H,9-12,15H2,1H3,(H,25,31)(H,26,28,32)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300606
PNG
(4-(methoxymethyl)-N-[5-(2-methylphenyl)-1,3,4-thia...)
Show SMILES COCc1ccc(cc1NC(=O)CN1CCOCC1)C(=O)Nc1nnc(s1)-c1ccccc1C
Show InChI InChI=1S/C24H27N5O4S/c1-16-5-3-4-6-19(16)23-27-28-24(34-23)26-22(31)17-7-8-18(15-32-2)20(13-17)25-21(30)14-29-9-11-33-12-10-29/h3-8,13H,9-12,14-15H2,1-2H3,(H,25,30)(H,26,28,31)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300609
PNG
(3-({[1- (dimethylamino)cyclopropyl] carbonyl}amino...)
Show SMILES CN(C)C1(CC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccccc1F
Show InChI InChI=1S/C25H22F4N4O3/c1-33(2)24(11-12-24)23(35)32-20-13-15(7-10-21(20)36-25(27,28)29)22(34)31-16-8-9-19(30-14-16)17-5-3-4-6-18(17)26/h3-10,13-14H,11-12H2,1-2H3,(H,31,34)(H,32,35)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300610
PNG
(N-[6-(3,5- difluorophenyl)pyridin-3-yl]-3- ({(2R*)...)
Show SMILES CC(N1C[C@@H]2C[C@H]1CO2)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1cc(F)cc(F)c1
Show InChI InChI=1S/C27H23F5N4O4/c1-14(36-12-21-10-20(36)13-39-21)25(37)35-23-8-15(2-5-24(23)40-27(30,31)32)26(38)34-19-3-4-22(33-11-19)16-6-17(28)9-18(29)7-16/h2-9,11,14,20-21H,10,12-13H2,1H3,(H,34,38)(H,35,37)/t14?,20-,21-/m0/s1
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300612
PNG
(N-[6-(3-fluorophenyl)pyridin-3- yl]-3-{[2-(morphol...)
Show SMILES CC(N1CCOCC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1cccc(F)c1
Show InChI InChI=1S/C26H24F4N4O4/c1-16(34-9-11-37-12-10-34)24(35)33-22-14-18(5-8-23(22)38-26(28,29)30)25(36)32-20-6-7-21(31-15-20)17-3-2-4-19(27)13-17/h2-8,13-16H,9-12H2,1H3,(H,32,36)(H,33,35)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300621
PNG
(3-[(morpholin-4- ylacetyl)amino]-N-(5-phenyl- 1,3,...)
Show SMILES FC(F)(F)Oc1ccc(cc1NC(=O)CN1CCOCC1)C(=O)Nc1nnc(o1)-c1ccccc1
Show InChI InChI=1S/C22H20F3N5O5/c23-22(24,25)35-17-7-6-15(12-16(17)26-18(31)13-30-8-10-33-11-9-30)19(32)27-21-29-28-20(34-21)14-4-2-1-3-5-14/h1-7,12H,8-11,13H2,(H,26,31)(H,27,29,32)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300625
PNG
(N-[6-(4-hydroxyphenyl)pyridin- 3-yl]-3-{[2-(morpho...)
Show SMILES CC(N1CCOCC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccc(O)cc1
Show InChI InChI=1S/C26H25F3N4O5/c1-16(33-10-12-37-13-11-33)24(35)32-22-14-18(4-9-23(22)38-26(27,28)29)25(36)31-19-5-8-21(30-15-19)17-2-6-20(34)7-3-17/h2-9,14-16,34H,10-13H2,1H3,(H,31,36)(H,32,35)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300626
PNG
(3-{[2-(4-cyclopropylpiperazin-1- yl)propanoyl]amin...)
Show SMILES CC(N1CCN(CC1)C1CC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccccc1F
Show InChI InChI=1S/C29H29F4N5O3/c1-18(37-12-14-38(15-13-37)21-8-9-21)27(39)36-25-16-19(6-11-26(25)41-29(31,32)33)28(40)35-20-7-10-24(34-17-20)22-4-2-3-5-23(22)30/h2-7,10-11,16-18,21H,8-9,12-15H2,1H3,(H,35,40)(H,36,39)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300642
PNG
(6-(2-fluorophenyl)-N-[3-{[2-(8- oxa-3-azabicyclo[3...)
Show SMILES CC(N1CC2CCC(C1)O2)C(=O)Nc1cc(NC(=O)c2ccc(nc2)-c2ccccc2F)ccc1OC(F)(F)F
Show InChI InChI=1S/C28H26F4N4O4/c1-16(36-14-19-8-9-20(15-36)39-19)26(37)35-24-12-18(7-11-25(24)40-28(30,31)32)34-27(38)17-6-10-23(33-13-17)21-4-2-3-5-22(21)29/h2-7,10-13,16,19-20H,8-9,14-15H2,1H3,(H,34,38)(H,35,37)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300643
PNG
(6-(2-fluorophenyl)-N-[3-{[2- (morpholin-4- yl)prop...)
Show SMILES CC(N1CCOCC1)C(=O)Nc1cc(NC(=O)c2ccc(nc2)-c2ccccc2F)ccc1OC(F)(F)F
Show InChI InChI=1S/C26H24F4N4O4/c1-16(34-10-12-37-13-11-34)24(35)33-22-14-18(7-9-23(22)38-26(28,29)30)32-25(36)17-6-8-21(31-15-17)19-4-2-3-5-20(19)27/h2-9,14-16H,10-13H2,1H3,(H,32,36)(H,33,35)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300615
PNG
(6-(3,5-difluorophenyl)-N-[3- ({(2R*)-2-[(1S,4S)-2-...)
Show SMILES CC(N1C[C@@H]2C[C@H]1CO2)C(=O)Nc1cc(NC(=O)c2ccc(nc2)-c2cc(F)cc(F)c2)ccc1OC(F)(F)F
Show InChI InChI=1S/C27H23F5N4O4/c1-14(36-12-21-10-20(36)13-39-21)25(37)35-23-9-19(3-5-24(23)40-27(30,31)32)34-26(38)15-2-4-22(33-11-15)16-6-17(28)8-18(29)7-16/h2-9,11,14,20-21H,10,12-13H2,1H3,(H,34,38)(H,35,37)/t14?,20-,21-/m0/s1
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300649
PNG
(6-(3,5-difluorophenyl)-N-[3-{[2- (morpholin-4- yl)...)
Show SMILES CC(N1CCOCC1)C(=O)Nc1cc(NC(=O)c2ccc(nc2)-c2cc(F)cc(F)c2)ccc1OC(F)(F)F
Show InChI InChI=1S/C26H23F5N4O4/c1-15(35-6-8-38-9-7-35)24(36)34-22-13-20(3-5-23(22)39-26(29,30)31)33-25(37)16-2-4-21(32-14-16)17-10-18(27)12-19(28)11-17/h2-5,10-15H,6-9H2,1H3,(H,33,37)(H,34,36)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300636
PNG
(6-(2-fluorophenyl)-N-[3-{[2- (morpholin-4- yl)prop...)
Show SMILES CC(N1CCOCC1)C(=O)Nc1cc(NC(=O)c2ccc(nc2)-c2ccccc2F)ccc1OC(F)(F)F
Show InChI InChI=1S/C26H24F4N4O4/c1-16(34-10-12-37-13-11-34)24(35)33-22-14-18(7-9-23(22)38-26(28,29)30)32-25(36)17-6-8-21(31-15-17)19-4-2-3-5-20(19)27/h2-9,14-16H,10-13H2,1H3,(H,32,36)(H,33,35)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300659
PNG
(6-(4-fluorophenyl)-N-{4- methoxy-3-[(morpholin-4- ...)
Show SMILES COc1ccc(NC(=O)c2ccc(nc2)-c2ccc(F)cc2)cc1NC(=O)CN1CCOCC1
Show InChI InChI=1S/C25H25FN4O4/c1-33-23-9-7-20(14-22(23)29-24(31)16-30-10-12-34-13-11-30)28-25(32)18-4-8-21(27-15-18)17-2-5-19(26)6-3-17/h2-9,14-15H,10-13,16H2,1H3,(H,28,32)(H,29,31)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300660
PNG
(3-{[2-(4-methylpiperazin-1- yl)propanoyl]amino}-4-...)
Show SMILES CC(N1CCN(C)CC1)C(=O)Nc1cc(ccc1CS(C)(=O)=O)C(=O)Nc1nnc(s1)-c1ccccc1
Show InChI InChI=1S/C25H30N6O4S2/c1-17(31-13-11-30(2)12-14-31)22(32)26-21-15-19(9-10-20(21)16-37(3,34)35)23(33)27-25-29-28-24(36-25)18-7-5-4-6-8-18/h4-10,15,17H,11-14,16H2,1-3H3,(H,26,32)(H,27,29,33)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300661
PNG
(3-{[2-(4-methylpiperazin-1- yl)propanoyl]amino}-4-...)
Show SMILES CC(N1CCN(C)CC1)C(=O)Nc1cc(ccc1CS(C)(=O)=O)C(=O)Nc1nnc(s1)-c1ccccc1
Show InChI InChI=1S/C25H30N6O4S2/c1-17(31-13-11-30(2)12-14-31)22(32)26-21-15-19(9-10-20(21)16-37(3,34)35)23(33)27-25-29-28-24(36-25)18-7-5-4-6-8-18/h4-10,15,17H,11-14,16H2,1-3H3,(H,26,32)(H,27,29,33)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300661
PNG
(3-{[2-(4-methylpiperazin-1- yl)propanoyl]amino}-4-...)
Show SMILES CC(N1CCN(C)CC1)C(=O)Nc1cc(ccc1CS(C)(=O)=O)C(=O)Nc1nnc(s1)-c1ccccc1
Show InChI InChI=1S/C25H30N6O4S2/c1-17(31-13-11-30(2)12-14-31)22(32)26-21-15-19(9-10-20(21)16-37(3,34)35)23(33)27-25-29-28-24(36-25)18-7-5-4-6-8-18/h4-10,15,17H,11-14,16H2,1-3H3,(H,26,32)(H,27,29,33)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300663
PNG
(N-[6-(2-fluorophenyl)pyridin-3- yl]-3-({[4-(2,2,2-...)
Show SMILES Fc1ccccc1-c1ccc(NC(=O)c2ccc(OC(F)(F)F)c(NC(=O)CN3CCN(CC(F)(F)F)CC3)c2)cn1
Show InChI InChI=1S/C27H24F7N5O3/c28-20-4-2-1-3-19(20)21-7-6-18(14-35-21)36-25(41)17-5-8-23(42-27(32,33)34)22(13-17)37-24(40)15-38-9-11-39(12-10-38)16-26(29,30)31/h1-8,13-14H,9-12,15-16H2,(H,36,41)(H,37,40)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300665
PNG
(4-[(methylsulfonyl)methyl]-3- [(morpholin-4-ylacet...)
Show SMILES CS(=O)(=O)Cc1ccc(cc1NC(=O)CN1CCOCC1)C(=O)Nc1nnc(s1)-c1ccccc1
Show InChI InChI=1S/C23H25N5O5S2/c1-35(31,32)15-18-8-7-17(13-19(18)24-20(29)14-28-9-11-33-12-10-28)21(30)25-23-27-26-22(34-23)16-5-3-2-4-6-16/h2-8,13H,9-12,14-15H2,1H3,(H,24,29)(H,25,27,30)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300666
PNG
(N-[6-(2-fluorophenyl)pyridin-3- yl]-3-({[1-(4-meth...)
Show SMILES CN1CCN(CC1)C1(CC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccccc1F
Show InChI InChI=1S/C28H27F4N5O3/c1-36-12-14-37(15-13-36)27(10-11-27)26(39)35-23-16-18(6-9-24(23)40-28(30,31)32)25(38)34-19-7-8-22(33-17-19)20-4-2-3-5-21(20)29/h2-9,16-17H,10-15H2,1H3,(H,34,38)(H,35,39)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300668
PNG
(4-(cyclopropyloxy)-N-[6-(2- fluorophenyl)pyridin-3...)
Show SMILES Fc1ccccc1-c1ccc(NC(=O)c2ccc(OC3CC3)c(NC(=O)Cc3ccccn3)c2)cn1
Show InChI InChI=1S/C28H23FN4O3/c29-23-7-2-1-6-22(23)24-12-9-20(17-31-24)32-28(35)18-8-13-26(36-21-10-11-21)25(15-18)33-27(34)16-19-5-3-4-14-30-19/h1-9,12-15,17,21H,10-11,16H2,(H,32,35)(H,33,34)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300669
PNG
(4-(difluoromethoxy)-3- [(morpholin-4-ylacetyl)amin...)
Show SMILES FC(F)Oc1ccc(cc1NC(=O)CN1CCOCC1)C(=O)Nc1nnc(s1)-c1ccccc1
Show InChI InChI=1S/C22H21F2N5O4S/c23-21(24)33-17-7-6-15(12-16(17)25-18(30)13-29-8-10-32-11-9-29)19(31)26-22-28-27-20(34-22)14-4-2-1-3-5-14/h1-7,12,21H,8-11,13H2,(H,25,30)(H,26,28,31)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300670
PNG
(3-[(8-oxa-3- azabicyclo[3.2.1]oct-3- ylacetyl)amin...)
Show SMILES FC(F)(F)Oc1ccc(cc1NC(=O)CN1CC2CCC(C1)O2)C(=O)Nc1nnc(s1)-c1ccccc1
Show InChI InChI=1S/C24H22F3N5O4S/c25-24(26,27)36-19-9-6-15(21(34)29-23-31-30-22(37-23)14-4-2-1-3-5-14)10-18(19)28-20(33)13-32-11-16-7-8-17(12-32)35-16/h1-6,9-10,16-17H,7-8,11-13H2,(H,28,33)(H,29,31,34)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300497
PNG
(3-({[1-(4-cyclopropylpiperazin-1-yl)cyclopropyl]ca...)
Show SMILES Fc1ccccc1-c1ccc(NC(=O)c2ccc(OC(F)(F)F)c(NC(=O)C3(CC3)N3CCN(CC3)C3CC3)c2)cn1
Show InChI InChI=1S/C30H29F4N5O3/c31-23-4-2-1-3-22(23)24-9-6-20(18-35-24)36-27(40)19-5-10-26(42-30(32,33)34)25(17-19)37-28(41)29(11-12-29)39-15-13-38(14-16-39)21-7-8-21/h1-6,9-10,17-18,21H,7-8,11-16H2,(H,36,40)(H,37,41)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300498
PNG
(N-[6-(2-fluorophenyl)pyridin-3-yl]-3-({[1-(morphol...)
Show SMILES Fc1ccccc1-c1ccc(NC(=O)c2ccc(OC(F)(F)F)c(NC(=O)C3(CC3)N3CCOCC3)c2)cn1
Show InChI InChI=1S/C27H24F4N4O4/c28-20-4-2-1-3-19(20)21-7-6-18(16-32-21)33-24(36)17-5-8-23(39-27(29,30)31)22(15-17)34-25(37)26(9-10-26)35-11-13-38-14-12-35/h1-8,15-16H,9-14H2,(H,33,36)(H,34,37)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300499
PNG
(N-[6-(3-fluorophenyl)pyridin-3-yl]-3-{[2-(morpholi...)
Show SMILES CC(N1CCOCC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1cccc(F)c1
Show InChI InChI=1S/C26H24F4N4O4/c1-16(34-9-11-37-12-10-34)24(35)33-22-14-18(5-8-23(22)38-26(28,29)30)25(36)32-20-6-7-21(31-15-20)17-3-2-4-19(27)13-17/h2-8,13-16H,9-12H2,1H3,(H,32,36)(H,33,35)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300503
PNG
(N-[6-(3,5-difluorophenyl)pyridin-3-yl]-3-[(8-oxa-3...)
Show SMILES Fc1cc(F)cc(c1)-c1ccc(NC(=O)c2ccc(OC(F)(F)F)c(NC(=O)CN3CC4CCC(C3)O4)c2)cn1
Show InChI InChI=1S/C27H23F5N4O4/c28-17-7-16(8-18(29)10-17)22-5-2-19(11-33-22)34-26(38)15-1-6-24(40-27(30,31)32)23(9-15)35-25(37)14-36-12-20-3-4-21(13-36)39-20/h1-2,5-11,20-21H,3-4,12-14H2,(H,34,38)(H,35,37)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300505
PNG
(N4-[6-(2-fluorophenyl)pyridin-3-yl]-2-({[1-(morpho...)
Show SMILES NC(=O)c1ccc(cc1NC(=O)C1(CC1)N1CCOCC1)C(=O)Nc1ccc(nc1)-c1ccccc1F
Show InChI InChI=1S/C27H26FN5O4/c28-21-4-2-1-3-19(21)22-8-6-18(16-30-22)31-25(35)17-5-7-20(24(29)34)23(15-17)32-26(36)27(9-10-27)33-11-13-37-14-12-33/h1-8,15-16H,9-14H2,(H2,29,34)(H,31,35)(H,32,36)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300506
PNG
(N-[6-(2-fluorophenyl)pyridin-3-yl]-4-methyl-3-({[1...)
Show SMILES Cc1ccc(cc1NC(=O)C1(CC1)N1CCOCC1)C(=O)Nc1ccc(nc1)-c1ccccc1F
Show InChI InChI=1S/C27H27FN4O3/c1-18-6-7-19(16-24(18)31-26(34)27(10-11-27)32-12-14-35-15-13-32)25(33)30-20-8-9-23(29-17-20)21-4-2-3-5-22(21)28/h2-9,16-17H,10-15H2,1H3,(H,30,33)(H,31,34)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300508
PNG
(4-fluoro-3-({[1-(morpholin-4-yl)cyclopropyl]carbon...)
Show SMILES Fc1ccc(cc1NC(=O)C1(CC1)N1CCOCC1)C(=O)Nc1nnc(s1)-c1ccccc1
Show InChI InChI=1S/C23H22FN5O3S/c24-17-7-6-16(19(30)26-22-28-27-20(33-22)15-4-2-1-3-5-15)14-18(17)25-21(31)23(8-9-23)29-10-12-32-13-11-29/h1-7,14H,8-13H2,(H,25,31)(H,26,28,30)
PDB

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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300509
PNG
(4-chloro-N-[6-(2-fluorophenyl)pyridin-3-yl]-3-({[1...)
Show SMILES Fc1ccccc1-c1ccc(NC(=O)c2ccc(Cl)c(NC(=O)C3(CC3)N3CCOCC3)c2)cn1
Show InChI InChI=1S/C26H24ClFN4O3/c27-20-7-5-17(15-23(20)31-25(34)26(9-10-26)32-11-13-35-14-12-32)24(33)30-18-6-8-22(29-16-18)19-3-1-2-4-21(19)28/h1-8,15-16H,9-14H2,(H,30,33)(H,31,34)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300510
PNG
(N-[6-(2-fluorophenyl)pyridin-3-yl]-4-methoxy-3-({[...)
Show SMILES COc1ccc(cc1NC(=O)C1(CC1)N1CCOCC1)C(=O)Nc1ccc(nc1)-c1ccccc1F
Show InChI InChI=1S/C27H27FN4O4/c1-35-24-9-6-18(16-23(24)31-26(34)27(10-11-27)32-12-14-36-15-13-32)25(33)30-19-7-8-22(29-17-19)20-4-2-3-5-21(20)28/h2-9,16-17H,10-15H2,1H3,(H,30,33)(H,31,34)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300511
PNG
(4-methoxy-3-({[1-(morpholin-4-yl)cyclopropyl]carbo...)
Show SMILES COc1ccc(cc1NC(=O)C1(CC1)N1CCOCC1)C(=O)Nc1ccc(nc1)-c1ccccc1
Show InChI InChI=1S/C27H28N4O4/c1-34-24-10-7-20(17-23(24)30-26(33)27(11-12-27)31-13-15-35-16-14-31)25(32)29-21-8-9-22(28-18-21)19-5-3-2-4-6-19/h2-10,17-18H,11-16H2,1H3,(H,29,32)(H,30,33)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300512
PNG
(N-[6-(2-fluorophenyl)pyridin-3-yl]-4-methoxy-3-({[...)
Show SMILES COc1ccc(cc1NC(=O)C1(CCC1)N1CCOCC1)C(=O)Nc1ccc(nc1)-c1ccccc1F
Show InChI InChI=1S/C28H29FN4O4/c1-36-25-10-7-19(17-24(25)32-27(35)28(11-4-12-28)33-13-15-37-16-14-33)26(34)31-20-8-9-23(30-18-20)21-5-2-3-6-22(21)29/h2-3,5-10,17-18H,4,11-16H2,1H3,(H,31,34)(H,32,35)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300513
PNG
(4-(methoxymethyl)-3-[(morpholin-4-ylacetyl)amino]-...)
Show SMILES COCc1ccc(cc1NC(=O)CN1CCOCC1)C(=O)Nc1nnc(s1)-c1ccccc1
Show InChI InChI=1S/C23H25N5O4S/c1-31-15-18-8-7-17(13-19(18)24-20(29)14-28-9-11-32-12-10-28)21(30)25-23-27-26-22(33-23)16-5-3-2-4-6-16/h2-8,13H,9-12,14-15H2,1H3,(H,24,29)(H,25,27,30)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300514
PNG
(3-{[(4-cyclopropylpiperazin-1-yl)acetyl]amino}-4-(...)
Show SMILES COCc1ccc(cc1NC(=O)CN1CCN(CC1)C1CC1)C(=O)Nc1nnc(s1)-c1ccccc1
Show InChI InChI=1S/C26H30N6O3S/c1-35-17-20-8-7-19(24(34)28-26-30-29-25(36-26)18-5-3-2-4-6-18)15-22(20)27-23(33)16-31-11-13-32(14-12-31)21-9-10-21/h2-8,15,21H,9-14,16-17H2,1H3,(H,27,33)(H,28,30,34)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300515
PNG
(3-{[N-(2-methoxyethyl)-N-methylglycyl]amino}-N-(5-...)
Show SMILES COCCN(C)CC(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1nnc(s1)-c1ccccc1
Show InChI InChI=1S/C22H22F3N5O4S/c1-30(10-11-33-2)13-18(31)26-16-12-15(8-9-17(16)34-22(23,24)25)19(32)27-21-29-28-20(35-21)14-6-4-3-5-7-14/h3-9,12H,10-11,13H2,1-2H3,(H,26,31)(H,27,29,32)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300516
PNG
(4-(difluoromethoxy)-3-[(8-oxa-3-azabicyclo[3.2.1]o...)
Show SMILES FC(F)Oc1ccc(cc1NC(=O)CN1CC2CCC(C1)O2)C(=O)Nc1nnc(s1)-c1ccccc1
Show InChI InChI=1S/C24H23F2N5O4S/c25-23(26)35-19-9-6-15(21(33)28-24-30-29-22(36-24)14-4-2-1-3-5-14)10-18(19)27-20(32)13-31-11-16-7-8-17(12-31)34-16/h1-6,9-10,16-17,23H,7-8,11-13H2,(H,27,32)(H,28,30,33)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300518
PNG
(3-{[2-(4-methylpiperazin-1-yl)propanoyl]amino}-4-[...)
Show SMILES CC(N1CCN(C)CC1)C(=O)Nc1cc(ccc1CS(C)(=O)=O)C(=O)Nc1nnc(s1)-c1ccccc1
Show InChI InChI=1S/C25H30N6O4S2/c1-17(31-13-11-30(2)12-14-31)22(32)26-21-15-19(9-10-20(21)16-37(3,34)35)23(33)27-25-29-28-24(36-25)18-7-5-4-6-8-18/h4-10,15,17H,11-14,16H2,1-3H3,(H,26,32)(H,27,29,33)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
Protein Wnt-3a


(Homo sapiens (Human))
BDBM300520
PNG
(N-[5-(4-fluorophenyl)-1,3,4-thiadiazol-2-yl]-3-({[...)
Show SMILES Fc1ccc(cc1)-c1nnc(NC(=O)c2ccc(OC(F)(F)F)c(NC(=O)C3(CC3)N3CCOCC3)c2)s1
Show InChI InChI=1S/C24H21F4N5O4S/c25-16-4-1-14(2-5-16)20-31-32-22(38-20)30-19(34)15-3-6-18(37-24(26,27)28)17(13-15)29-21(35)23(7-8-23)33-9-11-36-12-10-33/h1-6,13H,7-12H2,(H,29,35)(H,30,32,34)
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BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...


US Patent US10130633 (2018)

More data for this
Ligand-Target Pair
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