Found 176 hits of ic50 for drug = Acetazolamide Sodium Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
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| 0.343 | n/a | 0.485 | n/a | n/a | n/a | n/a | n/a | n/a |
Cumhuriyet University
| Assay Description Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr... |
Bioorg Chem 70: 118-125 (2017)
Article DOI: 10.1016/j.bioorg.2016.12.001 BindingDB Entry DOI: 10.7270/Q2CF9NZB |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
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| 0.747 | n/a | 0.996 | n/a | n/a | n/a | n/a | n/a | n/a |
Cumhuriyet University
| Assay Description Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr... |
Bioorg Chem 70: 118-125 (2017)
Article DOI: 10.1016/j.bioorg.2016.12.001 BindingDB Entry DOI: 10.7270/Q2CF9NZB |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
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| n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of GST-tagged recombinant carbonic anhydrase-9 catalytic domain (unknown origin) |
Bioorg Med Chem Lett 23: 3496-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.04.048 BindingDB Entry DOI: 10.7270/Q2GH9KFD |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
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| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Inc.
Curated by ChEMBL
| Assay Description Activity against human carbonic anhydrase II |
J Med Chem 37: 1646-51 (1994)
Article DOI: 10.1021/jm00037a015 BindingDB Entry DOI: 10.7270/Q2N015M1 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
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| n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | 7.4 | 25 |
University of Marburg
| Assay Description Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt... |
J Med Chem 45: 3588-602 (2002)
Article DOI: 10.1021/jm011112j BindingDB Entry DOI: 10.7270/Q2RJ4GQP |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
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| n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assay |
Eur J Med Chem 62: 597-604 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.030 BindingDB Entry DOI: 10.7270/Q2X92CNX |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
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| PDB Article PubMed
| n/a | n/a | 8.88 | n/a | n/a | n/a | n/a | n/a | n/a |
Alcon Research, Ltd.
| Assay Description The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy... |
Bioorg Med Chem 8: 957-75 (2000)
Article DOI: 10.1016/j.bmc.2009.03.013 BindingDB Entry DOI: 10.7270/Q23B5XC0 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
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| n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
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| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description In vitro inhibition of purified human erythrocyte carbonic anhydrase II |
J Med Chem 36: 2134-41 (1993)
Article DOI: 10.1021/jm00067a012 BindingDB Entry DOI: 10.7270/Q2GX49N1 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
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| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp& Dohme Research Laboratory
Curated by ChEMBL
| Assay Description In vitro inhibition of human Carbonic Anhydrase II |
J Med Chem 32: 2486-92 (1989)
Article DOI: 10.1021/jm00131a011 BindingDB Entry DOI: 10.7270/Q27P90KQ |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
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| PDB Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp& Dohme Research Laboratories
Curated by ChEMBL
| Assay Description 50% inhibition of human carbonic anhydrase II assayed by CO2 hydration catalyzed by human erythrocytes |
J Med Chem 32: 2548-54 (1989)
Article DOI: 10.1021/jm00132a009 BindingDB Entry DOI: 10.7270/Q23X87TJ |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
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| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Bruker-AXS s.r.l.
Curated by ChEMBL
| Assay Description Inhibitory activity of compound against human carbonic anhydrase II |
Bioorg Med Chem Lett 14: 337-41 (2003)
Article DOI: 10.1016/j.bmcl.2003.11.014 BindingDB Entry DOI: 10.7270/Q2W66MBZ |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
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| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Compound was tested for inhibition of human carbonic anhydrase (hCA II) |
Bioorg Med Chem Lett 13: 863-5 (2003)
Article DOI: 10.1016/s0960-894x(03)00009-x BindingDB Entry DOI: 10.7270/Q2319WFW |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
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| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Perugia
Curated by ChEMBL
| Assay Description Inhibition of CA-2 (unknown origin) after 15 mins by CO2 hydration assay |
Bioorg Med Chem Lett 24: 3422-5 (2014)
Article DOI: 10.1016/j.bmcl.2014.05.086 BindingDB Entry DOI: 10.7270/Q20003Q8 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 6
(Bos taurus) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | UniProtKB/SwissProt
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| | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description In vitro concentration that causes 50% inhibition of carbonic anhydrase carbonate hydro-lyase (EC.4.2.1.1) isolated from bovine erythrocyte |
Citation and Details
|
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
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| PDB Article PubMed
| n/a | n/a | 16.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 in presence of 0.01 mM beta-mercaptoethanol |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
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| n/a | n/a | 16.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 in presence of 0.01 mM tris(carboxyethyl)phosphine |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 4
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
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| Article PubMed
| n/a | n/a | 17.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Alcon Research, Ltd.
| Assay Description The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy... |
Bioorg Med Chem 8: 957-75 (2000)
Article DOI: 10.1016/j.bmc.2009.03.013 BindingDB Entry DOI: 10.7270/Q23B5XC0 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
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| n/a | n/a | 18.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 in presence of 0.01 mM threitol |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
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| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of full length carbonic anhydrase-2 in human erythrocytes |
Bioorg Med Chem Lett 23: 3496-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.04.048 BindingDB Entry DOI: 10.7270/Q2GH9KFD |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
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| PDB Article PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
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| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 2 pretreated for 15 mins by stopped flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 2617-20 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.077 BindingDB Entry DOI: 10.7270/Q2GB25KV |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
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| PDB Article PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | 7.4 | 25 |
GITAM University
| Assay Description An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes as repo... |
J Enzyme Inhib Med Chem 27: 97-100 (2012)
Article DOI: 10.3109/14756366.2011.578393 BindingDB Entry DOI: 10.7270/Q2HH6HZG |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet 
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| PDB Article PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | 7.8 | 20 |
St. Maryamppound39s Hospital
| Assay Description The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ... |
Biochem Biophys Res Commun 305: 909-14 (2003)
Article DOI: 10.1021/jo802139s BindingDB Entry DOI: 10.7270/Q2TD9VKK |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet 
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Patents
Similars
| PDB Article PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 assessed as 4-nitrophenyl acetate hydrolysis |
Bioorg Med Chem Lett 18: 2267-71 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.012 BindingDB Entry DOI: 10.7270/Q2G44Q10 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
Similars
| PDB Article PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM
Curated by ChEMBL
| Assay Description Inhibition of human erythrocyte carbonic anhydrase-2 assessed as hydrolysis of 4-nitrophenylacetate |
J Med Chem 55: 10909-17 (2012)
Article DOI: 10.1021/jm301506h BindingDB Entry DOI: 10.7270/Q2Z60Q6R |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
Similars
| PDB Article PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 catalytic domain |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
Similars
| PDB Article PubMed
| n/a | n/a | 34.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 in presence of 0.05 mM tris(carboxyethyl)phosphine |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| PDB Article PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 in presence of 0.05 mM threitol |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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| PDB Article PubMed
| n/a | n/a | 36.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 in presence of 0.01 mM tris(carboxyethyl)phosphine |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
Similars
| PDB Article PubMed
| n/a | n/a | 36.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 in presence of 0.01 mM threitol |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| PDB Article PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Erzurum Technical University
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 using 4-nitrophenylacetate as substrate by spectrophotometric analysis |
Bioorg Med Chem 24: 2318-29 (2016)
Article DOI: 10.1016/j.bmc.2016.04.002 BindingDB Entry DOI: 10.7270/Q2930W3J |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
Similars
| PDB Article PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay |
Eur J Med Chem 62: 597-604 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.030 BindingDB Entry DOI: 10.7270/Q2X92CNX |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
Similars
| PDB Article PubMed
| n/a | n/a | 42.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 in presence of 0.01 mM beta-mercaptoethanol |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 44.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 catalytic domain in presence of 0.01 mM beta-mercaptoethanol |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet 
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 47.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 in presence of 0.10 mM tris(carboxyethyl)phosphine |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic Anhydrase XIV
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet 
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi 'Aldo Moro' di Bari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration method |
Bioorg Med Chem Lett 24: 1941-3 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.001 BindingDB Entry DOI: 10.7270/Q2PV6MWT |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet 
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi 'Aldo Moro' di Bari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration method |
Bioorg Med Chem Lett 24: 1941-3 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.001 BindingDB Entry DOI: 10.7270/Q2PV6MWT |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet 
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 48.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 in presence of 0.25 mM tris(carboxyethyl)phosphine |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet 
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 48.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 in presence of 1.00 mM tris(carboxyethyl)phosphine |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 48.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 in presence of 0.05 mM tris(carboxyethyl)phosphine |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet 
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 48.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 in presence of 0.05 mM beta-mercaptoethanol |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet 
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 52.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 in presence of 0.05 mM threitol |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet 
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 53.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 in presence of 0.10 mM beta-mercaptoethanol |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet 
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 53.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 in presence of 0.10 mM tris(carboxyethyl)phosphine |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet 
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 in presence of 0.05 mM beta-mercaptoethanol |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet 
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 56.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 in presence of 10 mM tris(carboxyethyl)phosphine |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet 
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 56.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 in presence of 0.10 mM threitol |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 12
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet 
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Perugia
Curated by ChEMBL
| Assay Description Inhibition of CA-12 (unknown origin) after 15 mins by CO2 hydration assay |
Bioorg Med Chem Lett 24: 3422-5 (2014)
Article DOI: 10.1016/j.bmcl.2014.05.086 BindingDB Entry DOI: 10.7270/Q20003Q8 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (human)) | BDBM10880
 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet 
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 60.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 in presence of 0.25 mM beta-mercaptoethanol |
Bioorg Med Chem Lett 18: 1898-903 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.008 BindingDB Entry DOI: 10.7270/Q2RN37M3 |
More data for this Ligand-Target Pair |  3D Structure (crystal) |