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Found 4 of kd for monomerid = 10887
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)
Affinity DataKd:  290nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)
Affinity DataKd:  290nMpH: 7.5Assay Description:Binding affinity to human carbonic anhydrase 2 in presence of 10 mM HEPES and 100 uM Na2SO4 at pH 7.5 by ThermoFluor methodMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)
Affinity DataKd:  13.8nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Istituto Di Biostrutture E Bioimmagini-Cnr

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)
Affinity DataKd:  25.4nMAssay Description:Inhibition of human carbonic anhydrase 5AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed