TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataKi: 1.58E+3nMAssay Description:Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptorMore data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
The University Of Kansas
Curated by ChEMBL
The University Of Kansas
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of bovine PNMT by radiochemical assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.80E+3nM ΔG°: -7.43kcal/molepH: 8.0 T: 2°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
Affinity DataKi: 5.80E+3nMAssay Description:Binding affinity to human PNMTMore data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
The University Of Kansas
Curated by ChEMBL
The University Of Kansas
Curated by ChEMBL
Affinity DataKi: 6.67E+3nMAssay Description:Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
The University Of Kansas
Curated by ChEMBL
The University Of Kansas
Curated by ChEMBL
Affinity DataKi: 9.67E+3nMAssay Description:In vitro for inhibition of Phenylethanolamine N-Methyltransferase (PNMT)More data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
The University Of Kansas
Curated by ChEMBL
The University Of Kansas
Curated by ChEMBL
Affinity DataKi: 9.70E+3nMAssay Description:Inhibitory constant against bovine phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
The University Of Kansas
Curated by ChEMBL
The University Of Kansas
Curated by ChEMBL
Affinity DataKi: 9.70E+3nMAssay Description:In vitro inhibitory activity against bovine adrenal phenylethanolamine N-methyltransferase(PNMT)More data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
The University Of Kansas
Curated by ChEMBL
The University Of Kansas
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:In vitro inhibitory activity against bovine adrenal phenylethanolamine N-methyl transferaseMore data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
The University Of Kansas
Curated by ChEMBL
The University Of Kansas
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:In vitro inhibition of PNMT (Phenylethanolamine N-Methyltransferase).More data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
The University Of Kansas
Curated by ChEMBL
The University Of Kansas
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Inhibition of PNMT (Phenylethanolamine N-Methyltransferase) in vitro More data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
The University Of Kansas
Curated by ChEMBL
The University Of Kansas
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Binding affinity of the compound to phenylethanolamine N-methyltransferase(PNMT) in bovineMore data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
The University Of Kansas
Curated by ChEMBL
The University Of Kansas
Curated by ChEMBL
Affinity DataKi: 1.03E+4nMAssay Description:In vitro inhibition of bovine phenylethylamine N-methyl-transferase (PNMT) using radiochemical assay.More data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
The University Of Kansas
Curated by ChEMBL
The University Of Kansas
Curated by ChEMBL
Affinity DataKi: 1.03E+4nMAssay Description:In vitro inhibitory activity measured against bovine adrenal phenylethanolamine N-methyltransferase(PNMT)More data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
The University Of Kansas
Curated by ChEMBL
The University Of Kansas
Curated by ChEMBL
Affinity DataKi: 1.03E+4nMAssay Description:Inhibition of phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+4nMAssay Description:Compounds were tested for inhibition against human liver Monoamine oxidase B (competitive inhibition was observed)More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+4nMAssay Description:Inhibitory constant against human phenylethanolamine N-methyl-transferase over-expressed in Escherichia coliMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Polish Academy Of Sciences
Curated by ChEMBL
Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in the rat brain (hippocampus) using [3H]-8-OH-DPATMore data for this Ligand-Target Pair
Affinity DataKi: 2.10E+5nMAssay Description:Inhibition of human placental Monoamine oxidase A (competitive inhibition was observed)More data for this Ligand-Target Pair
Affinity DataKi: 4.70E+7nM ΔG°: -1.88kcal/molepH: 8.6 T: 2°CAssay Description:Enzyme activity assays were performed as previously described with NNMT (16.25 ug/mL, 550 nM) in 50 mM Tris buffer (pH 8.6) containing 1 mM DTT (all ...More data for this Ligand-Target Pair