Affinity DataKi: 14nMpH: 6.0Assay Description:Competitive Inhibition constant of the compound was determined on rice alpha Glucosidase at pH 8.0More data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Tested in vitro for the inhibition constant against rat small intestinal sucraseMore data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...More data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Tested in vitro for the inhibition constant against human lysosomal alpha-glucosidaseMore data for this Ligand-Target Pair
Affinity DataKi: 160nMpH: 5.0Assay Description:Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 5.0More data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:The inhibition of TreS by a range of known alpha-glucosidase inhibitor was assayed.More data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
Affinity DataKi: 9.50E+3nMAssay Description:Inhibitory activity against sweet almond Beta-glucosidaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Inhibition of Agrobacterium sp. beta glucosidaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Inhibition of Agrobacterium sp. beta-glucosidaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+4nM IC50: 3.95E+4nMAssay Description:All enzymatic activities were determined by using the appropriate substrate (p-nitrophenyl-alpha-D-glucopyranoside, p-nitrophenyl-beta-D-gulcopyranos...More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+4nMAssay Description:Compound tested for inhibition of alpha-galactosidase from Aspergillus nigerMore data for this Ligand-Target Pair
Affinity DataKi: 2.10E+4nMpH: 7.0Assay Description:Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 7.0More data for this Ligand-Target Pair
Affinity DataKi: 2.30E+4nMpH: 6.0Assay Description:Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 6.0More data for this Ligand-Target Pair
Affinity DataKi: 2.50E+4nMAssay Description:Inhibitory activity against alpha-glucosidase of yeastMore data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Technische Universit£T Berlin
Curated by ChEMBL
Technische Universit£T Berlin
Curated by ChEMBL
Affinity DataKi: 4.70E+4nMAssay Description:Inhibitory activity against beta-glucosidase of sweet almondMore data for this Ligand-Target Pair
Affinity DataKi: <5.00E+4nMAssay Description:Competitive Inhibitory activity against Golgi Alpha-mannosidase IIMore data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Technische Universit£T Berlin
Curated by ChEMBL
Technische Universit£T Berlin
Curated by ChEMBL
Affinity DataKi: 7.90E+4nM ΔG°: -5.82kcal/mole IC50: 2.40E+5nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Technische Universit£T Berlin
Curated by ChEMBL
Technische Universit£T Berlin
Curated by ChEMBL
Affinity DataKi: 7.90E+4nMAssay Description:Inhibition of human lysosomal beta-glucocerebrosidaseMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+5nMAssay Description:Inhibition of jack bean alpha-mannosidase using p-nitrophenyl-mannopyranoside as substrate measured every 2 minsMore data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Technische Universit£T Berlin
Curated by ChEMBL
Technische Universit£T Berlin
Curated by ChEMBL
Affinity DataKi: 3.00E+5nMpH: 5.0Assay Description:Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 7.0More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Technische Universit£T Berlin
Curated by ChEMBL
Technische Universit£T Berlin
Curated by ChEMBL
Affinity DataKi: 3.00E+5nMpH: 5.0Assay Description:Competitive Inhibition constant of the compound was determined on almonds beta Glucosidase at pH 5.0More data for this Ligand-Target Pair
Affinity DataKi: 4.10E+5nMAssay Description:Tested for competitive inhibition of golgi alpha mannosidase IIMore data for this Ligand-Target Pair
Affinity DataKi: 4.60E+5nMpH: 5.0Assay Description:Competitive Inhibition constant of the compound was determined on rice alpha Glucosidase at pH 5.0More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+7nM ΔG°: -2.63kcal/molepH: 5.6 T: 2°CAssay Description:Putative mannosidase assay using wild-type protein Btman2A. Enzyme inhibition assay.More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+8nMAssay Description:Inhibition constant against Alpha-FucosidaseMore data for this Ligand-Target Pair