Compile Data Set for Download or QSAR
maximum 50k data
Found 26 of ec50 for monomerid = 214799
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  51nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as beta-arrestin2 recruitment by enzyme fragment complementation meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Q115A](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  72nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Y119A](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  590nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Y119F](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  140nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [I135A](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  1.70E+3nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [D138A](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  36nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [D138N](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  9.10nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Y139A](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  400nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Y139F](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  140nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [M142A](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  28nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [K200A](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  80nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [K212A](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  1.30E+3nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [M226A](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  43nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [K227A](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  220nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [H291A](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  890nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [H291F](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  230nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [I294A](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  350nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [E297A](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  65nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Y312A](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  360nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Y312F](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  71nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Y313A](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  320nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Y313F](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  58nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [I316A](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  400nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Y320F](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  300nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Y66A](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  150nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed