Affinity DataEC50: 680nMAssay Description:Compound was tested for its ability to stimulate adenylyl cyclase activity in CHO-beta-3 adrenergic receptor cell membrane.More data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Agonist activity at Homo sapiens (human) beta3 adrenoreceptorMore data for this Ligand-Target Pair
Affinity DataEC50: 290nMAssay Description:Agonistic activity against human Beta-2 adrenergic receptor by measuring cAMP accumulation in CHO cells expressing beta3-ARMore data for this Ligand-Target Pair
Affinity DataEC50: 5.90nMAssay Description:Agonist activity at human adrenergic beta3 receptor expressed in CHO cells assessed as [3H]cAMP levels by radiolabeled ligand based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 450nMAssay Description:Compound was evaluated for agonistic activity in human Beta-3 adrenergic receptor assay; partial weak agonistMore data for this Ligand-Target Pair
Affinity DataEC50: 1.70E+3nMAssay Description:Agonistic activity against human Beta-1 adrenergic receptor by measuring cAMP accumulation in CHO cells expressing beta3-ARMore data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Agonism of recombinant human beta-3 adrenergic receptor assayed by measuring cAMP accumulation in CHO cells expressing beta3-ARMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0950nMAssay Description:Agonistic activity against human Beta-3 adrenergic receptor as cAMP accumulation in CHO cells expressing beta3-ARMore data for this Ligand-Target Pair
Affinity DataEC50: 2.20nMAssay Description:Concentration required to effect a 50% relaxation of ferret detrusor basal toneMore data for this Ligand-Target Pair
Affinity DataEC50: 450nMAssay Description:Agonism against Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at human adrenergic beta-3 receptor expressed in CHO cells assessed as cAMP levels by DELFIA methodMore data for this Ligand-Target Pair
Affinity DataEC50: 2.19nMAssay Description:Agonistic activity towards beta-3 adrenoceptor. Mean concentration required to produce 50% relaxation of detrusor before the addition in the ferret d...More data for this Ligand-Target Pair
Affinity DataEC50: 680nMAssay Description:Ability to bind to human Beta-3 adrenergic receptor using membranes of stably transfected CHO cellsMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
American Cyanamid
Curated by ChEMBL
American Cyanamid
Curated by ChEMBL
Affinity DataEC50: 5.60E+3nMAssay Description:Compound was evaluated for its binding affinity towards Beta-1 adrenergic receptor in rat heart membrane by displacing [125I]- iodocyanopindololMore data for this Ligand-Target Pair
Affinity DataEC50: 1.70E+3nMAssay Description:Agonist activity at Homo sapiens (human) beta1 adrenoreceptorMore data for this Ligand-Target Pair
Affinity DataEC50: 290nMAssay Description:Agonist activity at Homo sapiens (human) beta2 adrenoreceptorMore data for this Ligand-Target Pair
Affinity DataEC50: 8.40nMAssay Description:Compound was evaluated in vitro for beta-adrenergic activity against beta-3 adrenergic receptor in rat epididymal fat pads by stimulation of glycerol...More data for this Ligand-Target Pair