BindingDB PrimarySearch

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Platelet-derived growth factor receptor alpha(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 1.90nMAssay Description:Inhibition of PDGFRalpha (unknown origin) preincubated for 10 mins followed by FAM-labeled peptide substrate addition measured after 1 hr by mobility...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Platelet-derived growth factor receptor alpha(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 2.30nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRalpha (550 to 1089 end residues) cytoplasmic domain expressed in baculovirus expression system preincu...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar

Potassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 2.60nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Vascular endothelial growth factor receptor 3(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 3nMAssay Description:Inhibition of recombinant human GST-tagged VEGFR3 cytoplasmic domain expressed in baculovirus expression system preincubated for 10 mins followed by ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 3.10nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Vascular endothelial growth factor receptor 3(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 3.20nMAssay Description:Inhibition of N-terminal GST tagged human VEGFR3 (798 to 1298 end residues) cytoplasmic domain expressed in baculovirus expression system preincubate...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 3.30nMAssay Description:Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system preincubated fo...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Platelet-derived growth factor receptor beta(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 3.5nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Platelet-derived growth factor receptor beta(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 3.70nMAssay Description:Inhibition of human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system preincubated...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Platelet-derived growth factor receptor beta(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 3.80nMAssay Description:Inhibition of N-terminal GST-fused human PDGFRbeta cytoplasmic domain (557 to 1106 (end) residues) expressed in baculovirus expression system using F...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 4.70nMAssay Description:Inhibition of N-terminal GST fused human VEGFR2 cytoplasmic domain (790 to 1356 (end) residues) expressed in baculovirus expression system using FAM-...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 8.5nMAssay Description:Inhibition of N-terminal biotinylated DYKDDDDK tagged human VEGFR2 (790 to 1356 end residues) cytoplasmic domain expressed in baculovirus expression ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 13nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Vascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 13nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Vascular endothelial growth factor receptor 3(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 13nMAssay Description:Inhibition of human VEGFR3More data for this Ligand-Target Pair

PDB MMDB Reactome pathway
UniProtKB/SwissProt
B.MOAD GoogleScholar

Vascular endothelial growth factor receptor 2(Mus musculus)
Boehringer Ingelheim Pharma

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 13nMAssay Description:Inhibition of mouse VEGFR2More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Proto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 16nMAssay Description:Inhibition of SRC (unknown origin) using FAM-labeled peptide and ATP as substrate preincubated for 10 mins followed by substrate addition measured af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 21nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 21nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Vascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 23nMAssay Description:Inhibition of GST-tagged human recombinant VEGFR1 cytoplasmic domain (781 to 1338 residues) expressed in baculovirus expression system using FAM-labe...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Vascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 23nMAssay Description:Inhibition of recombinant human GST-tagged VEGFR1 cytoplasmic domain (781 to 1338 residues) expressed in baculovirus expression system preincubated f...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Vascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 34nMAssay Description:Inhibition of human VEGFR1More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Vascular endothelial growth factor receptor 3(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 34nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Fibroblast growth factor receptor 2(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas Margarita Salas (Csic)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 37nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Fibroblast growth factor receptor 2(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas Margarita Salas (Csic)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 37nMAssay Description:Inhibition of human FGFR2More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Fibroblast growth factor receptor 2(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas Margarita Salas (Csic)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 37nMAssay Description:Inhibition of GST-tagged FGFR2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Fibroblast growth factor receptor 1(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas Margarita Salas (Csic)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 39nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Fibroblast growth factor receptor 1(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas Margarita Salas (Csic)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 41nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Maternal embryonic leucine zipper kinase(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 43nMAssay Description:MELK and its substrate, Bcl-G were both recombinantly expressed and purified for use in screening assays (See Methods). 752 compounds from an in-hous...More data for this Ligand-Target Pair

Details US Patent PDB

PDB KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Maternal embryonic leucine zipper kinase(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 43nMAssay Description:Inhibition of His6-tagged MELK catalytic domain (1 to 340 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using Bcl-GL as s...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Tyrosine-protein kinase Lyn(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 55nMAssay Description:Inhibition of LYN (unknown origin) using FAM-labeled peptide and ATP as substrate preincubated for 10 mins followed by substrate addition measured af...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Platelet-derived growth factor receptor alpha(Homo sapiens (Human))
Key Laboratory Of Structure-Based Drug Design And Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 59nMAssay Description:Inhibition of human PDGFRalphaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Platelet-derived growth factor receptor beta(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 65nMAssay Description:Inhibition of human PDGFRbetaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Fibroblast growth factor receptor 1(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas Margarita Salas (Csic)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 69nMAssay Description:Inhibition of human FGFR1More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Fibroblast growth factor receptor 1(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas Margarita Salas (Csic)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 69nMAssay Description:Inhibition of GST-tagged FGFR1 (unknown origin)More data for this Ligand-Target Pair

KEGG
UniProtKB/SwissProt
GoogleScholar

Platelet-derived growth factor receptor beta(Mus musculus (mouse))
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 85nMAssay Description:Inhibition of PDGFR in mouse NIH/3T3 cells assessed as reduction in recombinant human PDGF-BB-induced cell proliferation after 42 hrs by cell titer 9...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Fibroblast growth factor receptor 1(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas Margarita Salas (Csic)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 98nMAssay Description:Inhibition of N-terminal GST tagged human FGFR1 (398 to 822 end residues) cytoplasmic domain expressed in baculovirus expression system preincubated ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Fibroblast growth factor receptor 1(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas Margarita Salas (Csic)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 99nMAssay Description:Inhibition of N-terminal GST fused human recombinant FGFR1 cytoplasmic domain (398 to 822 (end) residues) expressed in baculovirus expression system ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Fibroblast growth factor receptor 1(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas Margarita Salas (Csic)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 99nMAssay Description:Inhibition of recombinant human GST-tagged FGFR1 cytoplasmic domain (398 to 822 residues) expressed in baculovirus expression system preincubated for...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Fibroblast growth factor receptor 3(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas Margarita Salas (Csic)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 108nMAssay Description:Inhibition of FGFR3 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Fibroblast growth factor receptor 3(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas Margarita Salas (Csic)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 108nMAssay Description:Inhibition of GST-tagged FGFR3 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Fibroblast growth factor receptor 3(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas Margarita Salas (Csic)

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 108nMAssay Description:Inhibition of human FGFR3More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Fibroblast growth factor receptor 4(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 610nMAssay Description:Inhibition of human FGFR4More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Fibroblast growth factor receptor 4(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: 610nMAssay Description:Inhibition of GST-tagged FGFR4 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Cyclin-dependent kinase 2(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: >1.00E+3nMAssay Description:Inhibition of CDK2 (unknown origin) using FAM-labeled peptide and ATP as substrate preincubated for 10 mins followed by substrate addition measured a...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Serine/threonine-protein kinase Chk1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)

IC50: >1.00E+3nMAssay Description:Inhibition of CHK (unknown origin) using FAM-labeled peptide and ATP as substrate preincubated for 10 mins followed by substrate addition measured af...More data for this Ligand-Target Pair