Affinity DataIC50: 7nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration against human nonpancreatic secretory phospholipase A2More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human group IIA phospholipase A2 incubated for 1 hrs by scintillation counter analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human sPLA2-2A expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration against human nonpancreatic secretory phospholipase A2More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant sPLA2-2A (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant sPLA2-10 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate preincubated for 10 mins foll...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Compound was tested for inhibition of porcine secretory pancreatic PLA2More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of pig group IB phospholipase A2 incubated for 1 hrs by scintillation counter analysisMore data for this Ligand-Target Pair
TargetGroup IIE secretory phospholipase A2(Homo sapiens (Human))
University Of Washington
Curated by ChEMBL
University Of Washington
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant sPLA2 G2EMore data for this Ligand-Target Pair
TargetGroup IIE secretory phospholipase A2(Homo sapiens (Human))
University Of Washington
Curated by ChEMBL
University Of Washington
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human group2E phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
Target85/88 kDa calcium-independent phospholipase A2(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free [14C]-AA formation after 30 mins by sc...More data for this Ligand-Target Pair
Target85/88 kDa calcium-independent phospholipase A2(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free [14C]-AA formation after 30 mins by sc...More data for this Ligand-Target Pair
TargetGroup IID secretory phospholipase A2(Homo sapiens (Human))
University Of Washington
Curated by ChEMBL
University Of Washington
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human group2D phospholipase A2 by [3H]oleic acid-labeled Escherichia coli membrane assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of mouse recombinant sPLA2 G2AMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of mouse recombinant sPLA2 G2AMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of mouse group2A phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant sPLA2 G10More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of mouse recombinant sPLA2 G2EMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of mouse recombinant sPLA2 G10More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of human group2X phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of mouse group2X phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of mouse group2E phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
Target85/88 kDa calcium-independent phospholipase A2(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 104nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS...More data for this Ligand-Target Pair
Target85/88 kDa calcium-independent phospholipase A2(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 104nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS...More data for this Ligand-Target Pair
Affinity DataIC50: 107nMAssay Description:Inhibition of human sPLA2X using 1,2-bis(heptanoylthio) glycerophosphocholine substrate incubated for 30 minsMore data for this Ligand-Target Pair
TargetGroup XIIB secretory phospholipase A2-like protein(Homo sapiens)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 114nMAssay Description:Inhibition of human recombinant sPLA2 assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
TargetGroup XIIB secretory phospholipase A2-like protein(Homo sapiens)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 114nMAssay Description:Inhibition of human recombinant sPLA2 assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 124nMAssay Description:Inhibition of recombinant human sPLA2-5 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: 125nMAssay Description:Inhibition of human group2A phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
TargetGroup IIF secretory phospholipase A2(Homo sapiens (Human))
University Of Washington
Curated by ChEMBL
University Of Washington
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human group2F phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
Target85/88 kDa calcium-independent phospholipase A2(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 131nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ...More data for this Ligand-Target Pair
TargetGroup XIIB secretory phospholipase A2-like protein(Homo sapiens)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 131nMAssay Description:Inhibition of human recombinant sPLA2 assessed as reduction in free FA formation after 30 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
Target85/88 kDa calcium-independent phospholipase A2(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 131nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ...More data for this Ligand-Target Pair
TargetGroup XIIB secretory phospholipase A2-like protein(Homo sapiens)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 131nMAssay Description:Inhibition of human recombinant sPLA2 assessed as reduction in free FA formation after 30 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of mouse group1B phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of mouse recombinant sPLA2 G1BMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using HDL as substrate pretreated for 20 mins followed by substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 228nMAssay Description:Inhibition of human group IB phospholipase A2 incubated for 1 hrs by scintillation counter analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 228nMAssay Description:Compound was tested for inhibition of human secretory pancreatic Phospholipase A2More data for this Ligand-Target Pair
Target85/88 kDa calcium-independent phospholipase A2(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPG as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc...More data for this Ligand-Target Pair
Target85/88 kDa calcium-independent phospholipase A2(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPG as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc...More data for this Ligand-Target Pair
Target85/88 kDa calcium-independent phospholipase A2(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPS as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc...More data for this Ligand-Target Pair
Target85/88 kDa calcium-independent phospholipase A2(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPS as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of mouse group2D phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant sPLA2 G5More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of human group2V phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
Target85/88 kDa calcium-independent phospholipase A2(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc...More data for this Ligand-Target Pair