TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Broad Institute
Curated by PubChem BioAssay
Broad Institute
Curated by PubChem BioAssay
Affinity DataEC50: 4.95E+4nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
Affinity DataEC50: >2.50E+5nMAssay Description:Inhibition of rat fetal brain CDK5 assessed as phosphorylated histone H1 levels by immuno-precipitationMore data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+3nMAssay Description:Inhibition of SYK in human mast cells assessed as reduction in mast cell degranulationMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Punjabi University
Curated by ChEMBL
Punjabi University
Curated by ChEMBL
Affinity DataEC50: 9.00E+3nMAssay Description:Stimulation of CFTR (unknown origin)More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Mus musculus)
Institute Of Chinese Materia Medica
Curated by ChEMBL
Institute Of Chinese Materia Medica
Curated by ChEMBL
Affinity DataEC50: 2.49E+4nMAssay Description:Agonist activity at mouse PPARgamma expressed in HEK293 cells co-expressing with Gal4 reporter vector after 24 hrs by dual-luciferase reporter assayMore data for this Ligand-Target Pair