Compile Data Set for Download or QSAR
maximum 50k data
Found 8 of ic50 for monomerid = 82507
TargetMu-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM82507((+/-)-Methadone | CAS_5967-73-7 | METHADONE | Meth...)
Affinity DataIC50:  4.10nMAssay Description:Binding affinity against mu-opiate receptor (human) using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDelta-type/Kappa-type/Mu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM82507((+/-)-Methadone | CAS_5967-73-7 | METHADONE | Meth...)
Affinity DataIC50:  51nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM82507((+/-)-Methadone | CAS_5967-73-7 | METHADONE | Meth...)
Affinity DataIC50:  51nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM82507((+/-)-Methadone | CAS_5967-73-7 | METHADONE | Meth...)
Affinity DataIC50:  512nMAssay Description:Binding affinity against opioid receptor kappa 1 using [3H]- U-69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM82507((+/-)-Methadone | CAS_5967-73-7 | METHADONE | Meth...)
Affinity DataIC50:  1.09E+3nMAssay Description:Binding affinity against delta-opiate receptor (human) using [3H]-DPDPE radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Tufts University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM82507((+/-)-Methadone | CAS_5967-73-7 | METHADONE | Meth...)
Affinity DataIC50:  7.50E+3nMAssay Description:TP_TRANSPORTER: inhibition of Rhodamine 123 transepithelial transport (basal to apical) (Rhodamine 123: 5 uM) in Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Reverse Proteomics Research Institute

Curated by ChEMBL
LigandPNGBDBM82507((+/-)-Methadone | CAS_5967-73-7 | METHADONE | Meth...)
Affinity DataIC50:  9.77E+3nMAssay Description:Inhibitory concentration against potassium channel HERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM82507((+/-)-Methadone | CAS_5967-73-7 | METHADONE | Meth...)
Affinity DataIC50:  3.74E+4nMAssay Description:Inhibition of Cav1.2 current measured using QPatch automatic path clamp system in CHO cells expressing Cav1.2, beta-2 and alpha-2/delta-1 subunitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed