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Found 8 of ki data for polymerid = 10067
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Toyama Chemical

Curated by ChEMBL
LigandPNGBDBM50044561(CHEMBL3222137)
Affinity DataKi:  1.54E+3nMAssay Description:Substrate inhibition of human UGT1A1-mediated T-5224 acyl O-glucuronide formation after 10 to 60 mins in presence of UDP-glucuronic acid by HPLC meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Toyama Chemical

Curated by ChEMBL
LigandPNGBDBM50044561(CHEMBL3222137)
Affinity DataKi:  4.67E+3nMAssay Description:Substrate inhibition of human UGT1A1-mediated T-5224 hydroxyl O-glucuronide formation after 10 to 60 mins in presence of UDP-glucuronic acid by HPLC ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Toyama Chemical

Curated by ChEMBL
LigandPNGBDBM50088502(CHEBI:5970 | CHEMBL3527329)
Affinity DataKi:  8.50E+3nMAssay Description:Substrate inhibition of human recombinant UGT1A1 assessed as IRI-O-5-monoglucuronide formation incubated for 5 mins prior to UDPGA addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Toyama Chemical

Curated by ChEMBL
LigandPNGBDBM50088502(CHEBI:5970 | CHEMBL3527329)
Affinity DataKi:  1.41E+4nMAssay Description:Substrate inhibition of human recombinant UGT1A1 assessed as IRI-O-4'-monoglucuronide formation incubated for 5 mins prior to UDPGA addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Toyama Chemical

Curated by ChEMBL
LigandPNGBDBM23411(5,6,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)
Affinity DataKi:  4.13E+4nMAssay Description:Drug metabolism assessed as human recombinant UGT1A1-mediated formation of scutellarein-7-O-glucuronide after 25 mins by HPLC/UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Toyama Chemical

Curated by ChEMBL
LigandPNGBDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)
Affinity DataKi:  5.20E+4nMAssay Description:Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Toyama Chemical

Curated by ChEMBL
LigandPNGBDBM50242284(CHEMBL487805 | scutellarin)
Affinity DataKi:  9.66E+4nMAssay Description:Drug metabolism assessed as human recombinant UGT1A1-mediated formation of scutellarein-6,7-diglucuronide after 25 mins by HPLC/UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Toyama Chemical

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Affinity DataKi:  2.21E+5nMAssay Description:Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed