Compile Data Set for Download or QSAR
maximum 50k data
Found 22 of ic50 data for polymerid = 10230
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of EphA1 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50204290(CHEMBL3979920 | US11077111, Compound IIIa | US2023...)
Affinity DataIC50:  31nMAssay Description:Inhibition of human recombinant GST-tagged EPHA1 cytoplasmic domain (568 to 976 residues) expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  50nMAssay Description:Inhibition of EPHA1 (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50330905(7-(2,6-difluoro-4-((1S,4S)-5-methyl-2,5-diazabicyc...)
Affinity DataIC50:  95nMAssay Description:Inhibition of EPHA1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  95.3nMAssay Description:Inhibition of human EPHA1 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  139nMAssay Description:Inhibition of human EPHA1 using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50322535(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...)
Affinity DataIC50:  143nMAssay Description:Binding affinity to human EPHA1 using poly[Glu:Tyr] (4:1) as substrate by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50592745(CHEMBL5188373)
Affinity DataIC50:  292nMAssay Description:Inhibition of EphA1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50584948(CHEMBL5092606)
Affinity DataIC50:  303nMAssay Description:Inhibition of human recombinant EPHA1 incubated for 1 hrs by HTRF KinEASE TK assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50584949(CHEMBL5089164)
Affinity DataIC50:  393nMAssay Description:Inhibition of human recombinant EPHA1 incubated for 1 hrs by HTRF KinEASE TK assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  630nMAssay Description:Inhibition of EPHA1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50358591(CHEMBL1923983)
Affinity DataIC50:  686nMAssay Description:Inhibition of EPHA1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM236557(US9365572, 5)
Affinity DataIC50:  1.47E+3nMpH: 7.5 T: 2°CAssay Description:Agents: 1-fold kinase buffer without MnCl2: 50 mM HEPES, pH 7.5, 0.0015% Brij-35, 10 mM MgCl2, 2 mM DTT. 1-fold kinase buffer with MnCl2: 50 mM HEPES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50428059(CHEMBL2322989)
Affinity DataIC50:  2.30E+3nMAssay Description:Displacement of ephrin-A1-Fc from EphA1 receptor Fc ectodomain (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human EPHA1 using poly[Glu:Tyr] (4:1) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50509949(CHEMBL4475216 | US11667631, Example 29)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EphA1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human EphA1 (568 to end residues) using KKKSPGEYVNIEF as substrate after 40 mins in presence of [gamma-33ATP] by radiometri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50556597(CHEMBL4756586)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of C-terminal NanoLuc-fused full length EPHA1 (unknown origin) expressed in HEK293T cells after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50551201(CHEMBL4761556)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of biotinylated ephrin-A1-Fc from human EphA1 Fc preincubated for 1 hr followed by ephrin-A1-FC addition and measured after 4 hrs by ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50359359(CHEMBL1929238)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of EPHA1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50182493(CHEMBL3818247 | US9512121, 22)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of EPHA1 (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of Protein kinase C beta 2 expressed in Sf-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed