BindingDB PrimarySearch

Found 25 hits of ic50 data for polymerid = 10355
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50421214 (CHEMBL2087633) Show SMILES Nc1cccc(c1)C1=N[C@@H](CS1)C(O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM21642 ((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...) Show SMILES C[C@H](CS)C(=O)N1CCC[C@H]1C(O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	Purchase CHEBI CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50421216 (CHEMBL2087635) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50335803 (3-hydroxy-2-methyl-4H-pyran-4-thione \| CHEMBL16506...) Show SMILES Cc1occc(=S)c1O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.59E+5	n/a	n/a	n/a	n/a	7.0	n/a
Baylor University					Assay Description Bla2, in 50 mM MOPS and 30% (v/v) glycerol, was assayed for substrate activity by adding enzyme at a final concentration of 0.13 μg/mL to soluti...				J Enzyme Inhib Med Chem 28: 137-42 (2013) Article DOI: 10.3109/14756366.2011.640632 BindingDB Entry DOI: 10.7270/Q26T0KHH
Baylor University					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50335803 (3-hydroxy-2-methyl-4H-pyran-4-thione \| CHEMBL16506...) Show SMILES Cc1occc(=S)c1O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.68E+5	n/a	n/a	n/a	n/a	7.0	n/a
Baylor University					Assay Description Bla2, in 50 mM MOPS and 30% (v/v) glycerol, was assayed for substrate activity by adding enzyme at a final concentration of 0.13 μg/mL to soluti...				J Enzyme Inhib Med Chem 28: 137-42 (2013) Article DOI: 10.3109/14756366.2011.640632 BindingDB Entry DOI: 10.7270/Q26T0KHH
Baylor University					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50421215 (CHEMBL2087634) Show SMILES CC(=O)Nc1cccc(c1)C1=N[C@@H](CS1)C(O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50421221 (CHEMBL1722922) Show SMILES OC(=O)c1csc(Cc2ccccc2)n1 Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50421226 (CHEMBL79962) Show SMILES OC(=O)[C@@H]1CSC(=N1)c1ccccc1O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	Purchase CHEBI CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50421227 (CHEMBL2087638) Show SMILES OC(=O)[C@@H]1CSC(CNC(=O)OCc2ccccc2)=N1 Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50421225 (CHEMBL2087632) Show SMILES OC(=O)[C@@H]1CSC(=N1)c1ccc(Br)cc1 Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50421217 (CHEMBL2086406) Show SMILES OC(=O)[C@@H]1CSC(CNC(=O)Cc2ccccc2)=N1 Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50421218 (CHEMBL2087636) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50421219 (CHEMBL2087637) Show SMILES CC(C)(C)OC(=O)NCC1=N[C@@H](CS1)C(O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50421223 (CHEMBL2087630) Show SMILES OC(=O)[C@@H]1CSC(Cc2ccccc2)N1 Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM63710 (2-phenyl-1,3-thiazole-4-carboxylic acid \| 2-phenyl...) Show SMILES OC(=O)c1csc(n1)-c1ccccc1 Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50421228 (CHEMBL2087323) Show SMILES OC(=O)[C@@H]1CSC(Cc2ccccc2)=N1 Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50421220 (CHEMBL2087628) Show SMILES OC(=O)[C@@H]1CSC(=N1)c1ccccc1 Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50421222 (CHEMBL2087629) Show SMILES OC(=O)[C@H]1CSC(=N1)c1ccccc1 Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50421224 (CHEMBL154191) Show SMILES OC(=O)[C@@H]1CSC(N1)c1ccccc1 Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50421229 (CHEMBL2087631) Show SMILES OC(=O)[C@@H]1CSC(=N1)c1ccc(Cl)cc1 Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate preincubated for 20 mins by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50335803 (3-hydroxy-2-methyl-4H-pyran-4-thione \| CHEMBL16506...) Show SMILES Cc1occc(=S)c1O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	2.04E+5	n/a	n/a	n/a	n/a	7.0	n/a
Baylor University					Assay Description Bla2, in 50 mM MOPS and 30% (v/v) glycerol, was assayed for substrate activity by adding enzyme at a final concentration of 0.13 μg/mL to soluti...				J Enzyme Inhib Med Chem 28: 137-42 (2013) Article DOI: 10.3109/14756366.2011.640632 BindingDB Entry DOI: 10.7270/Q26T0KHH
Baylor University					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50335803 (3-hydroxy-2-methyl-4H-pyran-4-thione \| CHEMBL16506...) Show SMILES Cc1occc(=S)c1O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	2.35E+5	n/a	n/a	n/a	n/a	7.0	n/a
Baylor University					Assay Description Bla2, in 50 mM MOPS and 30% (v/v) glycerol, was assayed for substrate activity by adding enzyme at a final concentration of 0.13 μg/mL to soluti...				J Enzyme Inhib Med Chem 28: 137-42 (2013) Article DOI: 10.3109/14756366.2011.640632 BindingDB Entry DOI: 10.7270/Q26T0KHH
Baylor University					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50335803 (3-hydroxy-2-methyl-4H-pyran-4-thione \| CHEMBL16506...) Show SMILES Cc1occc(=S)c1O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	2.90E+5	n/a	n/a	n/a	n/a	7.0	n/a
Baylor University					Assay Description Bla2, in 50 mM MOPS and 30% (v/v) glycerol, was assayed for substrate activity by adding enzyme at a final concentration of 0.13 μg/mL to soluti...				J Enzyme Inhib Med Chem 28: 137-42 (2013) Article DOI: 10.3109/14756366.2011.640632 BindingDB Entry DOI: 10.7270/Q26T0KHH
Baylor University					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50335803 (3-hydroxy-2-methyl-4H-pyran-4-thione \| CHEMBL16506...) Show SMILES Cc1occc(=S)c1O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	3.67E+5	n/a	n/a	n/a	n/a	7.0	n/a
Baylor University					Assay Description Bla2, in 50 mM MOPS and 30% (v/v) glycerol, was assayed for substrate activity by adding enzyme at a final concentration of 0.13 μg/mL to soluti...				J Enzyme Inhib Med Chem 28: 137-42 (2013) Article DOI: 10.3109/14756366.2011.640632 BindingDB Entry DOI: 10.7270/Q26T0KHH
Baylor University					More data for this Ligand-Target Pair
β-lactamase (Bla2) (Bacillus anthracis)	BDBM50330325 (2,2',2'',2'''-(ethane-1,2-diylbis(azanetriyl))tetr...) Show SMILES OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.06E+6	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of Bacillus anthracis MBL Bla2 using nitrocefin as substrate after 12 hrs by UV-spectrophotometric analysis				Bioorg Med Chem Lett 22: 6229-32 (2012) Article DOI: 10.1016/j.bmcl.2012.08.012 BindingDB Entry DOI: 10.7270/Q2CF9RCZ
Baylor College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair