Compile Data Set for Download or QSAR
maximum 50k data
Found 276 of ic50 for UniProtKB: P00760
TargetSerine protease 1(Bos taurus (bovine))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120225(2-{[2-(4-Guanidino-butyrylamino)-3-(4-nitro-phenyl...)
Affinity DataIC50:  0.00800nMAssay Description:Concentration of the compound required to inhibit Trypsin was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50228863((S)-1-((R)-2-Methylamino-3-phenyl-propionyl)-pyrro...)
Affinity DataIC50:  0.0450nMAssay Description:Concentration of the compound required to inhibit Trypsin was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50290996(3-tert-Butoxycarbonylamino-4-[2-(4-guanidino-1-phe...)
Affinity DataIC50:  0.760nMAssay Description:Compound was evaluated for its 50% inhibitory concentration against cow protease enzyme trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Bos taurus (bovine))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50291175(((R)-1-Benzyl-2-{(S)-2-[(R)-4-guanidino-1-(thiazol...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Bos taurus (bovine))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50291167(1-((S)-Oxo-3-(R)-2-amino-1-phenyl-propyl)-pyrrolid...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Bos taurus (bovine))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14140((2S)-1-[(2S)-2-amino-3-phenylpropanoyl]-N-[1-(1,3-...)
Affinity DataIC50:  5.80nMAssay Description:Trypsin-catalyzed hydrolysis rates were measured spectrophotometrically using bovine trypsin, a chromogenic substrate in aqueous buffer, and a microp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50029499(CHEMBL141834 | tert-butyloxy carbonyl-D-Phe-thiazo...)
Affinity DataIC50:  8.80nMAssay Description:In vitro Enzyme Inhibitory activity measured against TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50291173(1-((S)-2-Amino-3-(R)-phenyl-propionyl)-azetidine-2...)
Affinity DataIC50:  9nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Bos taurus (bovine))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50029498(1N-[2-{2-[4-amino(imino)methylamino-1-formyl-(1S)-...)
Affinity DataIC50:  9.60nMAssay Description:In vitro Enzyme Inhibitory activity measured against TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50029515(CHEMBL141584 | tert-butyloxy carbonyl-D-Phe-azetid...)
Affinity DataIC50:  9.70nMAssay Description:In vitro Enzyme Inhibitory activity measured against TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50029506(CHEMBL318998 | tert-butyloxy carbonyl-D-ethylpheny...)
Affinity DataIC50:  9.80nMAssay Description:In vitro Enzyme Inhibitory activity measured against TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588267(1-N'-(4-fluorophenyl)-1-N- [4-[6-(3-hydroxyazetidi...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588268(1-N-[4-[6-(azetidin-1-yl)-7- methoxyquinolin-4- yl...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588269(1-N'-(4-fluorophenyl)-1-N- [4-[6-(3-hydroxyazetidi...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588270(1-N-[4-[6-(3,3-difluoroazetidin- 1-yl)-7-methoxyqu...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588271(1-N'-(4-fluorophenyl)-1-N-[4-(7- methoxy-6-pyridin...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588272(1-N'-(4-fluorophenyl)-1-N-[4-(7- methoxy-6-pyridin...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588273(1-N'-(4-fluorophenyl)-1-N-[4-(7- methoxy-6-sulfamo...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588274(1-N'-(4-fluorophenyl)-1-N-[4-(7- methoxy-6- methyl...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588275(1-N'-(4-fluorophenyl)-1-N-[4-[7- methoxy-6-(1,3,4-...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM605720(US11673897, Compound 10 | methyl 4-[5-[[1-[(4- flu...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM605721(US11673897, Compound 11 | methyl 4-[3-chloro-5-[[1...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM605724(1-N'-[6-(6-carbamoyl-7- methoxyquinolin-4-yl)oxypy...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM605726(1-N'-[6-(6-carbamoyl-7- methoxyquinolin-4-yl)oxy-5...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM605727(1-N-(4-fluorophenyl)-1-N'-[6-[7- methoxy-6-(1H-pyr...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM605730(US11673897, Compound 82 | l-N'-[6-[(6,7-dimethoxy-...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588211(US11542259, Compound 5 | methyl 4-[4-[[1-[(4- fluo...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588213(1-N-[4-(6-carbamoyl-7- methoxyquinolin-4- yl)oxyph...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588214(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6- (methy...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588215(1-N-[4-[6-[2- (dimethylamino)ethylcarbamoyl]- 7-me...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588216(1-N'-(4-fluorophenyl)-N-[4-[7- methoxy-6-(2-piperi...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588217(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6-(2-morp...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588218(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6-(oxetan...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588219(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6- [(1-me...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588220(1-N-[4-[6-(azetidine-1- carbonyl)-7-methoxyquinoli...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588221(1-N'-(4-fluorophenyl)-1-N- [4-[6-(3-hydroxyazetidi...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588222(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6- [[(2R)...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588223(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6- [[(2S)...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588224(1-N-[4-(6-cyano-7- methoxyquinolin-4- yl)oxyphenyl...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588225(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6-(1,3-ox...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588232(1-N-[4-[6-carbamoyl-7-(3- morpholin-4- ylpropoxy)q...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588233(1-N-[4-[6-carbamoyl-7-(2- methoxyethoxy)quinolin-4...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588234(US11542259, Compound 128 | methyl 4-[2-chloro-4-[[...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588236(1-N'-[4-(6-carbamoyl-7- methoxyquinolin-4-yl)oxy-3...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588237(1-N'-[3-chloro-4-[7-methoxy-6 (methylcarbamoyl)qui...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588238(US11542259, Compound 129 | methyl 4-[2-fluoro-4-[[...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588240(1-N'-[4-(6-carbamoyl-7- methoxyquinolin-4-yl)oxy-3...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588241(1-N'-[3-fluoro-4-[7-methoxy-6 (methylcarbamoyl)qui...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588242(US11542259, Compound 140 | methyl 4-[4-[[1-[(4- fl...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588244(1-N-[4-(7-carbamoyl-6- methylquinolin-4-yl)oxyphen...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
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