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Found 63 of ic50 for UniProtKB: P11086
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM13014(7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...)
Affinity DataIC50:  3nMAssay Description:Inhibition of PNMTMore data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM13014(7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...)
Affinity DataIC50:  10nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM13014(7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...)
Affinity DataIC50:  10nMAssay Description:Dissociation constant(Ki) of compound was determined to measure PNMT-inhibitory potencyMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571947(CHEMBL4850929)
Affinity DataIC50:  24nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50240934(3-(hydroxymethyl)-N-(3,3,3-trifluoropropyl)-1,2,3,...)
Affinity DataIC50:  28nMAssay Description:Inhibition of PNMTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571953(CHEMBL4860541)
Affinity DataIC50:  34nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571933(CHEMBL4878216)
Affinity DataIC50:  34nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571932(CHEMBL4865150)
Affinity DataIC50:  39nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571952(CHEMBL4858396)
Affinity DataIC50:  51nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571944(CHEMBL4856749)
Affinity DataIC50:  55nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571025(CHEMBL4846932)
Affinity DataIC50:  61nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571943(CHEMBL4848465)
Affinity DataIC50:  78nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571945(CHEMBL4866147)
Affinity DataIC50:  79nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50028902(7,8-dichloro-2-[2-(7,8-dichloro-1,2,3,4-tetrahydro...)
Affinity DataIC50:  80nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571935(CHEMBL4878071)
Affinity DataIC50:  80nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571946(CHEMBL4859513)
Affinity DataIC50:  92nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50028908(7,8-dichloro-2-[4-(7,8-dichloro-1,2,3,4-tetrahydro...)
Affinity DataIC50:  100nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029108(6,7,8-Trichloro-1,2,3,4-tetrahydro-isoquinoline | ...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571950(CHEMBL4870464)
Affinity DataIC50:  110nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571931(CHEMBL4875387)
Affinity DataIC50:  110nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571951(CHEMBL4864780)
Affinity DataIC50:  130nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571949(CHEMBL4874534)
Affinity DataIC50:  130nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571940(CHEMBL4859147)
Affinity DataIC50:  150nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571955(CHEMBL4860402)
Affinity DataIC50:  180nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029107(8-Chloro-1,2,3,4-tetrahydro-isoquinoline | CHEMBL1...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029102(7-Chloro-1,2,3,4-tetrahydro-isoquinoline | CHEMBL1...)
Affinity DataIC50:  200nMAssay Description:Dissociation constant(Ki) of compound was determined to measure Phenylethanolamine N-methyltransferase inhibitory potencyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029101(5,6,7,8-Tetrachloro-1,2,3,4-tetrahydro-isoquinolin...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571954(CHEMBL4857544)
Affinity DataIC50:  210nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571934(CHEMBL4861291)
Affinity DataIC50:  240nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571930(CHEMBL4860139)
Affinity DataIC50:  280nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571925(CHEMBL4852474)
Affinity DataIC50:  280nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571939(CHEMBL4858522)
Affinity DataIC50:  290nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50028903(7,8-dichloro-2-[3-(7,8-dichloro-1,2,3,4-tetrahydro...)
Affinity DataIC50:  300nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029099(5,7,8-Trichloro-1,2,3,4-tetrahydro-isoquinoline | ...)
Affinity DataIC50:  300nMAssay Description:Dissociation constant(Ki) of compound was determined to measure Phenylethanolamine N-methyltransferase inhibitory potencyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571942(CHEMBL4851171)
Affinity DataIC50:  370nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571941(CHEMBL4846790)
Affinity DataIC50:  370nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571936(CHEMBL4872556)
Affinity DataIC50:  440nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571927(CHEMBL4870149)
Affinity DataIC50:  570nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50029106(2,3-Dichloro-benzylamine | CHEMBL13165)
Affinity DataIC50:  600nMAssay Description:Invitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571937(CHEMBL4846861)
Affinity DataIC50:  630nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571929(CHEMBL4860065)
Affinity DataIC50:  730nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571928(CHEMBL4869791)
Affinity DataIC50:  810nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571938(CHEMBL4875172)
Affinity DataIC50:  910nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50028910(7,8-dichloro-2-[6-(7,8-dichloro-1,2,3,4-tetrahydro...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50028901(7,8-Dichloro-2-ethyl-1,2,3,4-tetrahydro-isoquinoli...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50028914(7,8-dichloro-2-[7-(7,8-dichloro-1,2,3,4-tetrahydro...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50028911(7,8-dichloro-2-[8-(7,8-dichloro-1,2,3,4-tetrahydro...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50028909(2-(7,8-Dichloro-3,4-dihydro-1H-isoquinolin-2-yl)-e...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of rabbit adrenal phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571926(CHEMBL4872079)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Mus musculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571948(CHEMBL4870992)
Affinity DataIC50:  4.11E+3nMAssay Description:Inhibition of Mer in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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