Compile Data Set for Download or QSAR
maximum 50k data
Found 733 of ic50 for UniProtKB: P00747
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120225(2-{[2-(4-Guanidino-butyrylamino)-3-(4-nitro-phenyl...)
Affinity DataIC50:  0.230nMAssay Description:Concentration of the compound required to inhibit Plasmin was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50514073(CHEMBL4576519)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by MeOSuc-Ala-Phe-Lys-AMC substrate addition and measured after 30 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50514076(CHEMBL4456691)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by MeOSuc-Ala-Phe-Lys-AMC substrate addition and measured after 30 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50514062(CHEMBL4436082)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by MeOSuc-Ala-Phe-Lys-AMC substrate addition and measured after 30 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50514063(CHEMBL4447001)
Affinity DataIC50:  0.420nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by MeOSuc-Ala-Phe-Lys-AMC substrate addition and measured after 30 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50514065(CHEMBL4570952)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by MeOSuc-Ala-Phe-Lys-AMC substrate addition and measured after 30 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50514079(CHEMBL4449958)
Affinity DataIC50:  0.870nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by MeOSuc-Ala-Phe-Lys-AMC substrate addition and measured after 30 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50514077(CHEMBL4475211)
Affinity DataIC50:  1nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by MeOSuc-Ala-Phe-Lys-AMC substrate addition and measured after 30 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50514078(CHEMBL4582882)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by MeOSuc-Ala-Phe-Lys-AMC substrate addition and measured after 30 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50514075(CHEMBL4541084)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by MeOSuc-Ala-Phe-Lys-AMC substrate addition and measured after 30 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50029498(1N-[2-{2-[4-amino(imino)methylamino-1-formyl-(1S)-...)
Affinity DataIC50:  9.60nMAssay Description:In vitro Enzyme Inhibitory activity measured against PlasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124990(CHEMBL355376 | N-[4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against PlasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50291006(4-[2-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarb...)
Affinity DataIC50:  15nMAssay Description:Compound was evaluated in vitro for the inhibitory concentration required to inhibit human serine protease enzyme plasmin by 50%More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50046356(1-(2-Amino-2-phenyl-acetyl)-pyrrolidine-2-carboxyl...)
Affinity DataIC50:  19nMAssay Description:Compound was tested in vitro for inhibitory activity against t-PA (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50046352(1-(1,2,3,4-Tetrahydro-isoquinoline-3-carbonyl)-pyr...)
Affinity DataIC50:  19nMAssay Description:Compound was tested in vitro for inhibitory activity against t-PA (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50029507(CHEMBL2370860 | {(R)-2-[2-((S)-1-Formyl-4-guanidin...)
Affinity DataIC50:  22nMAssay Description:In vitro Enzyme Inhibitory activity measured against PlasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50514074(CHEMBL4539788)
Affinity DataIC50:  23nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by MeOSuc-Ala-Phe-Lys-AMC substrate addition and measured after 30 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50228863((S)-1-((R)-2-Methylamino-3-phenyl-propionyl)-pyrro...)
Affinity DataIC50:  25nMAssay Description:Concentration of the compound required to inhibit Plasmin was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM31487(substituted biphenyl derivative, 36aa)
Affinity DataIC50:  35nMT: 2°CAssay Description:The assay is an amidolytic assay based upon the absorbance of derivatized thiols from the hydrolysis of Z-Lys-SBzl (Bachem) in the presence of 5,5-Di...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50374312(CHEMBL270834)
Affinity DataIC50:  36nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50194743(CHEMBL214814 | diphenyl 1-[(N-alpha-toluenesulfony...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50194743(CHEMBL214814 | diphenyl 1-[(N-alpha-toluenesulfony...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50046360(CHEMBL104472 | {1-Benzyl-2-[2-(1-formyl-4-guanidin...)
Affinity DataIC50:  45nMAssay Description:Compound was tested in vitro for inhibitory activity against t-PA (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50046358(CHEMBL110780 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  55nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM31497(substituted biphenyl derivative, 36ak)
Affinity DataIC50:  60nMT: 2°CAssay Description:The assay is an amidolytic assay based upon the absorbance of derivatized thiols from the hydrolysis of Z-Lys-SBzl (Bachem) in the presence of 5,5-Di...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM31467(substituted biphenyl derivative, 36g)
Affinity DataIC50:  70nMT: 2°CAssay Description:The assay is an amidolytic assay based upon the absorbance of derivatized thiols from the hydrolysis of Z-Lys-SBzl (Bachem) in the presence of 5,5-Di...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50046362(CHEMBL319930 | {1-Cyclohexyl-2-[2-(1-formyl-4-guan...)
Affinity DataIC50:  81nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50046362(CHEMBL319930 | {1-Cyclohexyl-2-[2-(1-formyl-4-guan...)
Affinity DataIC50:  81nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50046372(CHEMBL318998 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  98nMAssay Description:Compound was tested in vitro for inhibitory activity against t-PA (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50046372(CHEMBL318998 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  98nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50029506(CHEMBL318998 | tert-butyloxy carbonyl-D-ethylpheny...)
Affinity DataIC50:  98nMAssay Description:In vitro Enzyme Inhibitory activity measured against PlasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50478449(MICROPEPTIN 478-A | Micropeptin 478 A)
Affinity DataIC50:  102nMAssay Description:Inhibition of plasmin after 30 mins by microtiter plate methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetSolute carrier organic anion transporter family member 4C1(Homo sapiens)
Tohoku University

Curated by ChEMBL
LigandPNGBDBM46356(DIGITOXIN | MLS000069787 | SMR000058529 | US106680...)
Affinity DataIC50:  120nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin uptake in OATP4C1-expressing MDCK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50124992(CHEMBL162461 | N-[(R)-4-Guanidino-1-(thiazole-2-ca...)
Affinity DataIC50:  121nMAssay Description:Inhibitory activity against PlasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50088985(CHEMBL369042 | {2-[2-(1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  125nMAssay Description:The compound was tested in vitro for its inhibitory activity against human Plasmin enzyme, activity expressed as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM31469(substituted biphenyl derivative, 36i)
Affinity DataIC50:  127nMT: 2°CAssay Description:The assay is an amidolytic assay based upon the absorbance of derivatized thiols from the hydrolysis of Z-Lys-SBzl (Bachem) in the presence of 5,5-Di...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138156(Biphenyl-4-carboxylic acid {1-[(3-aminomethyl-phen...)
Affinity DataIC50: >130nMAssay Description:Compound was tested for inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50046368(CHEMBL320988 | [2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50029510(1N-[2-{2-[4-amino(imino)methylamino-1-formyl-(1S)-...)
Affinity DataIC50:  150nMAssay Description:In vitro Enzyme Inhibitory activity measured against PlasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50046361(CHEMBL2370418 | {2-[2-(1-Formyl-4-guanidino-butylc...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM31488(substituted biphenyl derivative, 36ab)
Affinity DataIC50:  163nMT: 2°CAssay Description:The assay is an amidolytic assay based upon the absorbance of derivatized thiols from the hydrolysis of Z-Lys-SBzl (Bachem) in the presence of 5,5-Di...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138161(CHEMBL321466 | N-{1-[(3-Aminomethyl-phenylcarbamoy...)
Affinity DataIC50: >170nMAssay Description:Compound was tested for inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50046359(CHEMBL109109 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50046373(CHEMBL108670 | {1-(3,4-Dichloro-phenyl)-2-[2-(1-fo...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50046361(CHEMBL2370418 | {2-[2-(1-Formyl-4-guanidino-butylc...)
Affinity DataIC50:  190nMAssay Description:Compound was tested in vitro for inhibitory activity against t-PA (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50029511(CHEMBL104472 | tert-butyloxy carbonyl-D-Phe-pro-Ar...)
Affinity DataIC50:  190nMAssay Description:In vitro Enzyme Inhibitory activity measured against PlasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50046360(CHEMBL104472 | {1-Benzyl-2-[2-(1-formyl-4-guanidin...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50183877(((R)-2-{(S)-2-[(4-carbamimidoyl-thiazol-2-ylmethyl...)
Affinity DataIC50:  201nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50138893(CHEMBL3752964)
Affinity DataIC50:  220nMAssay Description:Inhibition of plasmin (unknown origin) using H-D-Val-Leu-Lys-pNA as substrateMore data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM31500(substituted biphenyl derivative, 36an)
Affinity DataIC50:  229nMT: 2°CAssay Description:The assay is an amidolytic assay based upon the absorbance of derivatized thiols from the hydrolysis of Z-Lys-SBzl (Bachem) in the presence of 5,5-Di...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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