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Found 14 of ki for UniProtKB: Q920D2
TargetDihydrofolate reductase(Rattus norvegicus (rat))
University

Curated by ChEMBL
LigandPNGBDBM50059955(4-({[4-(2,4-Diamino-6-ethyl-pyrimidin-5-yl)-2-nitr...)
Affinity DataKi:  0.000350nMAssay Description:Inhibitory activity of compound against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
University

Curated by ChEMBL
LigandPNGBDBM50059948(4-({[4-(2,4-Diamino-6-ethyl-pyrimidin-5-yl)-2-nitr...)
Affinity DataKi:  0.000400nMAssay Description:Inhibitory activity of compound against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
University

Curated by ChEMBL
LigandPNGBDBM50058420((methylbenzoprim, MBP) 5-[4-(Benzyl-methyl-amino)-...)
Affinity DataKi:  0.00900nMAssay Description:Inhibitory activity of compound against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
University

Curated by ChEMBL
LigandPNGBDBM50059957(4-({[4-(2,4-Diamino-6-ethyl-pyrimidin-5-yl)-2-nitr...)
Affinity DataKi:  0.0140nMAssay Description:Inhibitory activity of compound against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
University

Curated by ChEMBL
LigandPNGBDBM50059956(5-(3,4-DICHLOROPHENYL)-6-METHYLPYRIMIDINE-2,4-DIAM...)
Affinity DataKi:  0.120nMAssay Description:Inhibitory activity of compound against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
University

Curated by ChEMBL
LigandPNGBDBM50006906(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)-am...)
Affinity DataKi:  0.580nMAssay Description:Compound was evaluated for the inhibition of partially purified rat liver Dihydrofolate reductase (DHFR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
University

Curated by ChEMBL
LigandPNGBDBM50017876(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataKi:  3.90nMAssay Description:Compound was evaluated for the inhibition of partially purified rat liver Dihydrofolate reductase (DHFR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
University

Curated by ChEMBL
LigandPNGBDBM50006907(2-{4-[(4-Oxo-3,4-dihydro-quinazolin-6-ylmethyl)-am...)
Affinity DataKi:  11nMAssay Description:Compound was evaluated for the inhibition of partially purified rat liver Dihydrofolate reductase (DHFR) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
University

Curated by ChEMBL
LigandPNGBDBM50017875(2-{4-[Ethyl-(4-oxo-3,4-dihydro-quinazolin-6-ylmeth...)
Affinity DataKi:  58nMAssay Description:Compound was evaluated for the inhibition of partially purified rat liver Dihydrofolate reductase (DHFR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
University

Curated by ChEMBL
LigandPNGBDBM18771((2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-...)
Affinity DataKi:  75nMAssay Description:Inhibitory activity against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
University

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)
Affinity DataKi:  75nMAssay Description:Compound was evaluated for the inhibition of partially purified rat liver Dihydrofolate reductase(DHFR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
University

Curated by ChEMBL
LigandPNGBDBM50014480((S)-2-(4-(((4-oxo-3,4-dihydroquinazolin-6-yl)methy...)
Affinity DataKi:  2.25E+3nMAssay Description:Inhibitory activity against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
University

Curated by ChEMBL
LigandPNGBDBM50011243(2-{4-[(4-Hydroxy-quinazolin-6-ylmethyl)-prop-2-yny...)
Affinity DataKi:  2.25E+3nMAssay Description:Compound was evaluated for the inhibition of partially purified rat liver Dihydrofolate reductase (DHFR) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
University

Curated by ChEMBL
LigandPNGBDBM50006687((S)-2-(4-(((2-methyl-4-oxo-3,4-dihydroquinazolin-6...)
Affinity DataKi: >2.66E+3nMAssay Description:Inhibitory activity against Dihydrofolate reductase in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed