Compile Data Set for Download or QSAR
maximum 50k data
Found 40 of ic50 data for polymerid = 1988
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50185589((E)-2-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50185592((E)-(4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihyd...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50123317(7-Methoxy-6-oxazol-5-yl-2-p-tolyl-1H-quinolin-4-on...)
Affinity DataIC50:  46nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  55nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50123320(7-Methoxy-6-oxazol-5-yl-2-thiophen-3-yl-1H-quinoli...)
Affinity DataIC50:  55nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50119045(1-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-m-tolyl-urea ...)
Affinity DataIC50:  55nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50185586((E)-4-(6-ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihydr...)
Affinity DataIC50:  71nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50123335(2-(3,4-Dimethyl-phenyl)-7-methoxy-6-oxazol-5-yl-1H...)
Affinity DataIC50:  83nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50123332(7-Methoxy-2-(4-methoxy-phenyl)-6-oxazol-5-yl-1H-qu...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50123324(7-Methoxy-6-oxazol-5-yl-2-phenyl-1H-quinolin-4-one...)
Affinity DataIC50:  99nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50123321(7-Methoxy-6-oxazol-5-yl-2-m-tolyl-1H-quinolin-4-on...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50054017((E)-6-(4,6-Dihydroxy-7-methyl-3-oxo-1,3-dihydro-is...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50126005(2-Benzo[b]thiophen-3-yl-6-methoxy-5-oxazol-5-yl-1H...)
Affinity DataIC50:  160nMAssay Description:Inhibition of 5'-inosine monophosphate dehydrogenase type I (IMPDH I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50228085(CHEMBL238461 | N-hydroxy-6-(4-hydroxy-6-methoxy-7-...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50331099(7-Hydroxy-6-((E)-6-hydroxy-3-methyl-hex-2-enyl)-5-...)
Affinity DataIC50:  770nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010605(6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-...)
Affinity DataIC50:  940nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50119012(1H-Indole-2-carboxylic acid (3-methoxy-4-oxazol-5-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity of compound was evaluated against the Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010602(3-[2-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihyd...)
Affinity DataIC50:  1.10E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010604(7-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50331100(CHEMBL237760 | methyl 6-(4-hydroxy-6-methoxy-7-met...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010609(7-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-...)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010611(6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-...)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010612(7-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010610(3-[2,2-Difluoro-3-(4-hydroxy-6-methoxy-7-methyl-3-...)
Affinity DataIC50:  2.60E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010606(6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-...)
Affinity DataIC50:  2.60E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010603(3-[2,2-Dibromo-3-(4-hydroxy-6-methoxy-7-methyl-3-o...)
Affinity DataIC50:  3.10E+3nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50331098(6-(4-acetoxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroi...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010608(3-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-...)
Affinity DataIC50:  1.09E+4nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50010607(4-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-...)
Affinity DataIC50:  2.27E+4nMAssay Description:In vitro inhibition of inosine Inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50209233(2-{(2S,3R,4S,5R)-5-[({[(2R,3S,4R,5R)-5-(6-amino-pu...)
Affinity DataIC50:  2.36E+4nMAssay Description:Inhibition of human IMP-dehydrogenase type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50263242(2-{(2R,3R,4S,5R)-5-[({[(2R,3S,4R,5R)-5-(6-Amino-pu...)
Affinity DataIC50:  2.36E+4nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM81328(methyl 3-methyl-2-oxo-1,2-dihydroquinoline-4-carbo...)
Affinity DataIC50: >2.50E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50294184(CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...)
Affinity DataIC50: >5.00E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM81327(Tetrahydroquinoxalin analog, J)
Affinity DataIC50: >5.00E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM81423(N-(4-methoxyphenyl)-2-[2-(1,3-thiazol-4-yl)-1H-1,3...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50331101(6-(4,6-dimethoxy-7-methyl-3-oxo-1,3-dihydroisobenz...)
Affinity DataIC50:  6.70E+4nMAssay Description:Inhibition of human IMPDH1 expressed in Escherichia coli strain BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM81329(N-[(Z)-N-(pyridin-3-yl)carboximidoyl]-2,3-dihydro-...)
Affinity DataIC50: >5.00E+5nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed