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Compile Data Set for Download or QSAR

Found 3 hits of non-affinity data for polymerid = 2142,49000103,49000104,49000107,49000108,49000109,8061   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM34155
PNG
(indenylsulfonamide, 26)
Show SMILES CN1CCC(C1)C1=C(C)Cc2ccc(NS(=O)(=O)c3sc4ccc(Cl)cc4c3C)cc12
Show InChI InChI=1S/C24H25ClN2O2S2/c1-14-10-16-4-6-19(12-21(16)23(14)17-8-9-27(3)13-17)26-31(28,29)24-15(2)20-11-18(25)5-7-22(20)30-24/h4-7,11-12,17,26H,8-10,13H2,1-3H3
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KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



Universitat de Barcelona



Assay Description
Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...


Bioorg Med Chem 17: 7387-97 (2009)


Article DOI: 10.1016/j.bmc.2009.08.006
BindingDB Entry DOI: 10.7270/Q2RR1WKS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM34160
PNG
(indenylsulfonamide, 49+50 | isomeric mixture (70% ...)
Show SMILES CC1=Cc2cccc(NS(=O)(=O)c3c(Cl)nc4sccn34)c2C1
Show InChI InChI=1S/C15H12ClN3O2S2/c1-9-7-10-3-2-4-12(11(10)8-9)18-23(20,21)14-13(16)17-15-19(14)5-6-22-15/h2-7,18H,8H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



Universitat de Barcelona



Assay Description
Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...


Bioorg Med Chem 17: 7387-97 (2009)


Article DOI: 10.1016/j.bmc.2009.08.006
BindingDB Entry DOI: 10.7270/Q2RR1WKS
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM34157
PNG
(indenylsulfonamide, 29)
Show SMILES CN1CCCC(C1)C1=C(C)Cc2ccc(NS(=O)(=O)c3sc4ccc(Cl)cc4c3C)cc12
Show InChI InChI=1S/C25H27ClN2O2S2/c1-15-11-17-6-8-20(13-22(17)24(15)18-5-4-10-28(3)14-18)27-32(29,30)25-16(2)21-12-19(26)7-9-23(21)31-25/h6-9,12-13,18,27H,4-5,10-11,14H2,1-3H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.437



Universitat de Barcelona



Assay Description
Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...


Bioorg Med Chem 17: 7387-97 (2009)


Article DOI: 10.1016/j.bmc.2009.08.006
BindingDB Entry DOI: 10.7270/Q2RR1WKS
More data for this
Ligand-Target Pair