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Compile Data Set for Download or QSAR

Found 98 hits of ec50 for UniProtKB: P14902   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM168435
PNG
(US9675571, 129)
Show SMILES CC(C)CN(C1CCCCC1)c1ccc(cc1NC(=O)Nc1cc(C)no1)[C@H]1C[C@H]1C(O)=O
Show InChI InChI=1S/C25H34N4O4/c1-15(2)14-29(18-7-5-4-6-8-18)22-10-9-17(19-13-20(19)24(30)31)12-21(22)26-25(32)27-23-11-16(3)28-33-23/h9-12,15,18-20H,4-8,13-14H2,1-3H3,(H,30,31)(H2,26,27,32)/t19-,20-/m1/s1
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n/an/an/an/a 0.5n/an/an/a25



SRMLSC

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM168360
PNG
(US9675571, 34)
Show SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1cc(no1)C1CC1)[C@H]1C[C@H]1C(O)=O
Show InChI InChI=1S/C25H34N4O4/c1-14(2)12-29(13-15(3)4)22-8-7-17(18-10-19(18)24(30)31)9-21(22)26-25(32)27-23-11-20(28-33-23)16-5-6-16/h7-9,11,14-16,18-19H,5-6,10,12-13H2,1-4H3,(H,30,31)(H2,26,27,32)/t18-,19-/m1/s1
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SRMLSC

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM168315
PNG
(US9675571, ent-1J)
Show SMILES COC(=O)C1CC1c1ccc(N(CC(C)C)CC(C)C)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C19H28N2O4/c1-12(2)10-20(11-13(3)4)17-7-6-14(8-18(17)21(23)24)15-9-16(15)19(22)25-5/h6-8,12-13,15-16H,9-11H2,1-5H3
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SRMLSC

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM168358
PNG
(US9675571, 31)
Show SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1cc(C)no1)[C@@H]1C[C@@H]1C(O)=O
Show InChI InChI=1S/C23H32N4O4/c1-13(2)11-27(12-14(3)4)20-7-6-16(17-10-18(17)22(28)29)9-19(20)24-23(30)25-21-8-15(5)26-31-21/h6-9,13-14,17-18H,10-12H2,1-5H3,(H,28,29)(H2,24,25,30)/t17-,18-/m0/s1
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SRMLSC

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM168337
PNG
(US9675571, 30)
Show SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1cc(C)no1)[C@H]1C[C@H]1C(O)=O
Show InChI InChI=1S/C23H32N4O4/c1-13(2)11-27(12-14(3)4)20-7-6-16(17-10-18(17)22(28)29)9-19(20)24-23(30)25-21-8-15(5)26-31-21/h6-9,13-14,17-18H,10-12H2,1-5H3,(H,28,29)(H2,24,25,30)/t17-,18-/m1/s1
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SRMLSC

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM168377
PNG
(US9675571, 36)
Show SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1cc(no1)C(F)(F)F)[C@H]1C[C@H]1C(O)=O
Show InChI InChI=1S/C23H29F3N4O4/c1-12(2)10-30(11-13(3)4)18-6-5-14(15-8-16(15)21(31)32)7-17(18)27-22(33)28-20-9-19(29-34-20)23(24,25)26/h5-7,9,12-13,15-16H,8,10-11H2,1-4H3,(H,31,32)(H2,27,28,33)/t15-,16-/m1/s1
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n/an/an/an/a 7n/an/an/a25



SRMLSC

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM168378
PNG
(US9675571, 37)
Show SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1cc(no1)C(F)(F)F)[C@@H]1C[C@@H]1C(O)=O
Show InChI InChI=1S/C23H29F3N4O4/c1-12(2)10-30(11-13(3)4)18-6-5-14(15-8-16(15)21(31)32)7-17(18)27-22(33)28-20-9-19(29-34-20)23(24,25)26/h5-7,9,12-13,15-16H,8,10-11H2,1-4H3,(H,31,32)(H2,27,28,33)/t15-,16-/m0/s1
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SRMLSC

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM168314
PNG
(US9675571, 1J)
Show SMILES COC(=O)[C@H]1C[C@H]1c1ccc(N(CC(C)C)CC(C)C)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C19H28N2O4/c1-12(2)10-20(11-13(3)4)17-7-6-14(8-18(17)21(23)24)15-9-16(15)19(22)25-5/h6-8,12-13,15-16H,9-11H2,1-5H3/t15-,16-/m0/s1
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n/an/an/an/a 8n/an/an/a25



SRMLSC

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50046104
PNG
(CHEMBL3310297)
Show SMILES O=S(=O)(CCc1ccccc1)NNc1ccccc1
Show InChI InChI=1S/C14H16N2O2S/c17-19(18,12-11-13-7-3-1-4-8-13)16-15-14-9-5-2-6-10-14/h1-10,15-16H,11-12H2
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n/an/an/an/a>10n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of IDO in human HeLa cells after 24 hrs by spectrophotometry


Bioorg Med Chem Lett 24: 3403-6 (2014)


Article DOI: 10.1016/j.bmcl.2014.05.084
BindingDB Entry DOI: 10.7270/Q23R0VH6
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM168399
PNG
(US9675571, 60)
Show SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Cc1ccc(C)cc1)[C@H]1C[C@H]1C(O)=O
Show InChI InChI=1S/C27H36N2O3/c1-17(2)15-29(16-18(3)4)25-11-10-21(22-14-23(22)27(31)32)13-24(25)28-26(30)12-20-8-6-19(5)7-9-20/h6-11,13,17-18,22-23H,12,14-16H2,1-5H3,(H,28,30)(H,31,32)/t22-,23-/m1/s1
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SRMLSC

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM168413
PNG
(US9675571, 67)
Show SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1cc(C)on1)C1C[C@@H]1C(O)=O
Show InChI InChI=1S/C23H32N4O4/c1-13(2)11-27(12-14(3)4)20-7-6-16(17-10-18(17)22(28)29)9-19(20)24-23(30)25-21-8-15(5)31-26-21/h6-9,13-14,17-18H,10-12H2,1-5H3,(H,28,29)(H2,24,25,26,30)/t17?,18-/m0/s1
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n/an/an/an/a 23n/an/an/a25



SRMLSC

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50145159
PNG
(CHEMBL3765205)
Show SMILES FC1(F)C(=O)Nc2ccc(cc12)S(=O)(=O)NNc1ccc(Br)cc1
Show InChI InChI=1S/C14H10BrF2N3O3S/c15-8-1-3-9(4-2-8)19-20-24(22,23)10-5-6-12-11(7-10)14(16,17)13(21)18-12/h1-7,19-20H,(H,18,21)
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n/an/an/an/a 31n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of Indoleamine 2,3-dioxygenase in human HeLa cells in presence of L-tryptophan as substrate after 24 hrs in presence of L-tryptophan


J Med Chem 59: 419-30 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01640
BindingDB Entry DOI: 10.7270/Q2FF3V69
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50145160
PNG
(CHEMBL3764846)
Show SMILES CC1(C)C(=O)Nc2ccc(cc12)S(=O)(=O)NNc1ccc(Br)cc1
Show InChI InChI=1S/C16H16BrN3O3S/c1-16(2)13-9-12(7-8-14(13)18-15(16)21)24(22,23)20-19-11-5-3-10(17)4-6-11/h3-9,19-20H,1-2H3,(H,18,21)
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n/an/an/an/a 36n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of Indoleamine 2,3-dioxygenase in human HeLa cells in presence of L-tryptophan as substrate after 24 hrs in presence of L-tryptophan


J Med Chem 59: 419-30 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01640
BindingDB Entry DOI: 10.7270/Q2FF3V69
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50203249
PNG
(CHEMBL3945146)
Show SMILES Cc1n[nH]c2Oc3[nH]nc(N)c3C(c12)c1ccc(F)c(F)c1
Show InChI InChI=1S/C14H11F2N5O/c1-5-9-10(6-2-3-7(15)8(16)4-6)11-12(17)19-21-14(11)22-13(9)20-18-5/h2-4,10H,1H3,(H,18,20)(H3,17,19,21)
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n/an/an/an/a 48n/an/an/an/a



Indian Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...


ACS Med Chem Lett 7: 1167-1172 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00359
BindingDB Entry DOI: 10.7270/Q2TF009K
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50203269
PNG
(CHEMBL3913434)
Show SMILES Cc1n[nH]c2Oc3[nH]nc(C)c3C(c12)c1ccc(F)c(Cl)c1
Show InChI InChI=1S/C15H12ClFN4O/c1-6-11-13(8-3-4-10(17)9(16)5-8)12-7(2)19-21-15(12)22-14(11)20-18-6/h3-5,13H,1-2H3,(H,18,20)(H,19,21)
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n/an/an/an/a 52n/an/an/an/a



Indian Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...


ACS Med Chem Lett 7: 1167-1172 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00359
BindingDB Entry DOI: 10.7270/Q2TF009K
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50203281
PNG
(CHEMBL3971895)
Show SMILES Clc1cccc(c1)-c1c(C#N)c(=O)[nH]c2[nH]c(=O)[nH]c(=O)c12
Show InChI InChI=1S/C14H7ClN4O3/c15-7-3-1-2-6(4-7)9-8(5-16)12(20)17-11-10(9)13(21)19-14(22)18-11/h1-4H,(H3,17,18,19,20,21,22)
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n/an/an/an/a 52n/an/an/an/a



Indian Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...


ACS Med Chem Lett 7: 1167-1172 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00359
BindingDB Entry DOI: 10.7270/Q2TF009K
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50138819
PNG
(CHEMBL3753837)
Show SMILES OC(CC1c2c(cccc2F)-c2cncn12)C1CCCCC1
Show InChI InChI=1S/C18H21FN2O/c19-14-8-4-7-13-16-10-20-11-21(16)15(18(13)14)9-17(22)12-5-2-1-3-6-12/h4,7-8,10-12,15,17,22H,1-3,5-6,9H2
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n/an/an/an/a 55n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells incubated for 24 hrs


J Med Chem 59: 282-93 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01390
BindingDB Entry DOI: 10.7270/Q28917QW
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50300305
PNG
(4-Amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2...)
Show SMILES Nc1nonc1C(NO)=Nc1ccc(F)c(Cl)c1
Show InChI InChI=1S/C9H7ClFN5O2/c10-5-3-4(1-2-6(5)11)13-9(14-17)7-8(12)16-18-15-7/h1-3,17H,(H2,12,16)(H,13,14)
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n/an/an/an/a 59n/an/an/an/a



Indian Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...


ACS Med Chem Lett 7: 1167-1172 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00359
BindingDB Entry DOI: 10.7270/Q2TF009K
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM168334
PNG
(US9675571, 20)
Show SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1ccc(cc1)C1CC1)[C@@H]1C[C@@H]1C(O)=O
Show InChI InChI=1S/C28H37N3O3/c1-17(2)15-31(16-18(3)4)26-12-9-21(23-14-24(23)27(32)33)13-25(26)30-28(34)29-22-10-7-20(8-11-22)19-5-6-19/h7-13,17-19,23-24H,5-6,14-16H2,1-4H3,(H,32,33)(H2,29,30,34)/t23-,24-/m0/s1
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n/an/an/an/a 61n/an/an/a25



SRMLSC

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50126144
PNG
(CHEMBL3629569 | US10155972, Compound NewLink 1)
Show SMILES OC(CC1c2ccccc2-c2cncn12)C1CCCCC1
Show InChI InChI=1S/C18H22N2O/c21-18(13-6-2-1-3-7-13)10-16-14-8-4-5-9-15(14)17-11-19-12-20(16)17/h4-5,8-9,11-13,16,18,21H,1-3,6-7,10H2
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n/an/an/an/a 61n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells incubated for 24 hrs


J Med Chem 59: 282-93 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01390
BindingDB Entry DOI: 10.7270/Q28917QW
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50145164
PNG
(CHEMBL3765698)
Show SMILES Oc1nc2cc(ccc2[nH]1)S(=O)(=O)NNc1ccc(Br)cc1
Show InChI InChI=1S/C13H11BrN4O3S/c14-8-1-3-9(4-2-8)17-18-22(20,21)10-5-6-11-12(7-10)16-13(19)15-11/h1-7,17-18H,(H2,15,16,19)
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n/an/an/an/a 63n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of Indoleamine 2,3-dioxygenase in human HeLa cells in presence of L-tryptophan as substrate after 24 hrs in presence of L-tryptophan


J Med Chem 59: 419-30 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01640
BindingDB Entry DOI: 10.7270/Q2FF3V69
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM168430
PNG
(US9675571, 77)
Show SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1cnc(C)nc1)[C@@H]1C[C@@H]1C(O)=O
Show InChI InChI=1S/C24H33N5O3/c1-14(2)12-29(13-15(3)4)22-7-6-17(19-9-20(19)23(30)31)8-21(22)28-24(32)27-18-10-25-16(5)26-11-18/h6-8,10-11,14-15,19-20H,9,12-13H2,1-5H3,(H,30,31)(H2,27,28,32)/t19-,20-/m0/s1
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n/an/an/an/a 64n/an/an/a25



SRMLSC

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50145161
PNG
(CHEMBL3765545)
Show SMILES Brc1ccc(NNS(=O)(=O)c2ccc3NC(=O)CCc3c2)cc1
Show InChI InChI=1S/C15H14BrN3O3S/c16-11-2-4-12(5-3-11)18-19-23(21,22)13-6-7-14-10(9-13)1-8-15(20)17-14/h2-7,9,18-19H,1,8H2,(H,17,20)
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n/an/an/an/a 67n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of Indoleamine 2,3-dioxygenase in human HeLa cells in presence of L-tryptophan as substrate after 24 hrs in presence of L-tryptophan


J Med Chem 59: 419-30 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01640
BindingDB Entry DOI: 10.7270/Q2FF3V69
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50145165
PNG
(CHEMBL3765220)
Show SMILES Nc1nc2cc(ccc2[nH]1)S(=O)(=O)NNc1ccc(Br)cc1
Show InChI InChI=1S/C13H12BrN5O2S/c14-8-1-3-9(4-2-8)18-19-22(20,21)10-5-6-11-12(7-10)17-13(15)16-11/h1-7,18-19H,(H3,15,16,17)
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n/an/an/an/a 68n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of Indoleamine 2,3-dioxygenase in human HeLa cells in presence of L-tryptophan as substrate after 24 hrs in presence of L-tryptophan


J Med Chem 59: 419-30 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01640
BindingDB Entry DOI: 10.7270/Q2FF3V69
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50145157
PNG
(CHEMBL3763166)
Show SMILES Brc1ccc(NNS(=O)(=O)c2ccc3NC(=O)Cc3c2)cc1
Show InChI InChI=1S/C14H12BrN3O3S/c15-10-1-3-11(4-2-10)17-18-22(20,21)12-5-6-13-9(7-12)8-14(19)16-13/h1-7,17-18H,8H2,(H,16,19)
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n/an/an/an/a 68n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of Indoleamine 2,3-dioxygenase in human HeLa cells in presence of L-tryptophan as substrate after 24 hrs in presence of L-tryptophan


J Med Chem 59: 419-30 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01640
BindingDB Entry DOI: 10.7270/Q2FF3V69
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50203279
PNG
(CHEMBL3940383)
Show SMILES Cc1n[nH]c2Oc3[nH]nc(C)c3C(c12)c1ccc(F)c(F)c1
Show InChI InChI=1S/C15H12F2N4O/c1-6-11-13(8-3-4-9(16)10(17)5-8)12-7(2)19-21-15(12)22-14(11)20-18-6/h3-5,13H,1-2H3,(H,18,20)(H,19,21)
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n/an/an/an/a 71n/an/an/an/a



Indian Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...


ACS Med Chem Lett 7: 1167-1172 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00359
BindingDB Entry DOI: 10.7270/Q2TF009K
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50203280
PNG
(CHEMBL3966057)
Show SMILES Nc1n[nH]c2Oc3[nH]nc(N)c3C(c12)c1ccc(F)c(F)c1
Show InChI InChI=1S/C13H10F2N6O/c14-5-2-1-4(3-6(5)15)7-8-10(16)18-20-12(8)22-13-9(7)11(17)19-21-13/h1-3,7H,(H3,16,18,20)(H3,17,19,21)
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n/an/an/an/a 73n/an/an/an/a



Indian Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...


ACS Med Chem Lett 7: 1167-1172 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00359
BindingDB Entry DOI: 10.7270/Q2TF009K
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50203255
PNG
(CHEMBL3913975)
Show SMILES NC1=C(C#N)C(c2cccc(Cl)c2)c2c(N1)[nH]c(=O)[nH]c2=O
Show InChI InChI=1S/C14H10ClN5O2/c15-7-3-1-2-6(4-7)9-8(5-16)11(17)18-12-10(9)13(21)20-14(22)19-12/h1-4,9H,17H2,(H3,18,19,20,21,22)
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n/an/an/an/a 75n/an/an/an/a



Indian Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...


ACS Med Chem Lett 7: 1167-1172 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00359
BindingDB Entry DOI: 10.7270/Q2TF009K
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50203275
PNG
(CHEMBL3971417)
Show SMILES Cc1n[nH]c2Oc3[nH]c(=O)[nH]c(=O)c3C(c12)c1ccc(F)c(F)c1
Show InChI InChI=1S/C15H10F2N4O3/c1-5-9-10(6-2-3-7(16)8(17)4-6)11-12(22)18-15(23)19-13(11)24-14(9)21-20-5/h2-4,10H,1H3,(H,20,21)(H2,18,19,22,23)
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n/an/an/an/a 76n/an/an/an/a



Indian Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...


ACS Med Chem Lett 7: 1167-1172 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00359
BindingDB Entry DOI: 10.7270/Q2TF009K
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50203260
PNG
(CHEMBL3974564)
Show SMILES Cc1n[nH]c2Oc3[nH]nc(N)c3C(c12)c1ccc(F)c(Cl)c1
Show InChI InChI=1S/C14H11ClFN5O/c1-5-9-10(6-2-3-8(16)7(15)4-6)11-12(17)19-21-14(11)22-13(9)20-18-5/h2-4,10H,1H3,(H,18,20)(H3,17,19,21)
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n/an/an/an/a 81n/an/an/an/a



Indian Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...


ACS Med Chem Lett 7: 1167-1172 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00359
BindingDB Entry DOI: 10.7270/Q2TF009K
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50203268
PNG
(CHEMBL3909480)
Show SMILES Cc1n[nH]c2Oc3[nH]c(=O)[nH]c(=O)c3C(c12)c1ccc(F)c(Cl)c1
Show InChI InChI=1S/C15H10ClFN4O3/c1-5-9-10(6-2-3-8(17)7(16)4-6)11-12(22)18-15(23)19-13(11)24-14(9)21-20-5/h2-4,10H,1H3,(H,20,21)(H2,18,19,22,23)
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n/an/an/an/a 83n/an/an/an/a



Indian Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...


ACS Med Chem Lett 7: 1167-1172 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00359
BindingDB Entry DOI: 10.7270/Q2TF009K
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50046139
PNG
(CHEMBL3310861)
Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)NNc1ccc(Cl)c(F)c1
Show InChI InChI=1S/C14H13ClFN3O3S/c1-9(20)17-10-2-5-12(6-3-10)23(21,22)19-18-11-4-7-13(15)14(16)8-11/h2-8,18-19H,1H3,(H,17,20)
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n/an/an/an/a 84n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of IDO in human HeLa cells after 24 hrs by spectrophotometry


Bioorg Med Chem Lett 24: 3403-6 (2014)


Article DOI: 10.1016/j.bmcl.2014.05.084
BindingDB Entry DOI: 10.7270/Q23R0VH6
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50046141
PNG
(CHEMBL3310854)
Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)NNc1ccc(Br)cc1
Show InChI InChI=1S/C14H14BrN3O3S/c1-10(19)16-12-6-8-14(9-7-12)22(20,21)18-17-13-4-2-11(15)3-5-13/h2-9,17-18H,1H3,(H,16,19)
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n/an/an/an/a 85n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of IDO in human HeLa cells after 24 hrs by spectrophotometry


Bioorg Med Chem Lett 24: 3403-6 (2014)


Article DOI: 10.1016/j.bmcl.2014.05.084
BindingDB Entry DOI: 10.7270/Q23R0VH6
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM168324
PNG
(US9675571, 14)
Show SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1ccc(C)cc1Cl)[C@H]1C[C@H]1C(O)=O
Show InChI InChI=1S/C26H34ClN3O3/c1-15(2)13-30(14-16(3)4)24-9-7-18(19-12-20(19)25(31)32)11-23(24)29-26(33)28-22-8-6-17(5)10-21(22)27/h6-11,15-16,19-20H,12-14H2,1-5H3,(H,31,32)(H2,28,29,33)/t19-,20-/m1/s1
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US Patent
n/an/an/an/a 86n/an/an/a25



SRMLSC

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM168396
PNG
(US9675571, 43)
Show SMILES COCCN(Cc1ccc(Cl)cc1)c1ccc(cc1NC(=O)Nc1ccc(C)cc1)[C@H]1C[C@H]1C(O)=O
Show InChI InChI=1S/C28H30ClN3O4/c1-18-3-10-22(11-4-18)30-28(35)31-25-15-20(23-16-24(23)27(33)34)7-12-26(25)32(13-14-36-2)17-19-5-8-21(29)9-6-19/h3-12,15,23-24H,13-14,16-17H2,1-2H3,(H,33,34)(H2,30,31,35)/t23-,24-/m1/s1
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n/an/an/an/a 88n/an/an/a25



SRMLSC

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50145169
PNG
(CHEMBL3763974)
Show SMILES Brc1ccc(NNS(=O)(=O)c2ccc(cc2)N2CCCC2=O)cc1
Show InChI InChI=1S/C16H16BrN3O3S/c17-12-3-5-13(6-4-12)18-19-24(22,23)15-9-7-14(8-10-15)20-11-1-2-16(20)21/h3-10,18-19H,1-2,11H2
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n/an/an/an/a 90n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of Indoleamine 2,3-dioxygenase in human HeLa cells in presence of L-tryptophan as substrate after 24 hrs in presence of L-tryptophan


J Med Chem 59: 419-30 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01640
BindingDB Entry DOI: 10.7270/Q2FF3V69
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM168433
PNG
(US9675571, 117)
Show SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Cc1ccc(F)cc1)[C@H]1C[C@H]1C(O)=O
Show InChI InChI=1S/C26H33FN2O3/c1-16(2)14-29(15-17(3)4)24-10-7-19(21-13-22(21)26(31)32)12-23(24)28-25(30)11-18-5-8-20(27)9-6-18/h5-10,12,16-17,21-22H,11,13-15H2,1-4H3,(H,28,30)(H,31,32)/t21-,22-/m1/s1
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n/an/an/an/a 97n/an/an/a25



SRMLSC

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM168322
PNG
(US9675571, 9)
Show SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1ccccc1Cl)[C@H]1C[C@H]1C(O)=O
Show InChI InChI=1S/C25H32ClN3O3/c1-15(2)13-29(14-16(3)4)23-10-9-17(18-12-19(18)24(30)31)11-22(23)28-25(32)27-21-8-6-5-7-20(21)26/h5-11,15-16,18-19H,12-14H2,1-4H3,(H,30,31)(H2,27,28,32)/t18-,19-/m1/s1
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n/an/an/an/a 97n/an/an/a25



SRMLSC

US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50203256
PNG
(CHEMBL3936225)
Show SMILES COc1ccc(cc1O)C1c2c(C)n[nH]c2Oc2[nH]nc(N)c12
Show InChI InChI=1S/C15H15N5O3/c1-6-10-11(7-3-4-9(22-2)8(21)5-7)12-13(16)18-20-15(12)23-14(10)19-17-6/h3-5,11,21H,1-2H3,(H,17,19)(H3,16,18,20)
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n/an/an/an/a 113n/an/an/an/a



Indian Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...


ACS Med Chem Lett 7: 1167-1172 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00359
BindingDB Entry DOI: 10.7270/Q2TF009K
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM168434
PNG
(US9675571, 118)
Show SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Cc1ccc(C)nc1)[C@H]1C[C@H]1C(O)=O
Show InChI InChI=1S/C26H35N3O3/c1-16(2)14-29(15-17(3)4)24-9-8-20(21-12-22(21)26(31)32)11-23(24)28-25(30)10-19-7-6-18(5)27-13-19/h6-9,11,13,16-17,21-22H,10,12,14-15H2,1-5H3,(H,28,30)(H,31,32)/t21-,22-/m1/s1
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n/an/an/an/a 126n/an/an/a25



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Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50046148
PNG
(CHEMBL3310973)
Show SMILES Brc1ccc(NNS(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C12H11BrN2O2S/c13-10-6-8-11(9-7-10)14-15-18(16,17)12-4-2-1-3-5-12/h1-9,14-15H
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n/an/an/an/a 128n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of IDO in human HeLa cells after 24 hrs by spectrophotometry


Bioorg Med Chem Lett 24: 3403-6 (2014)


Article DOI: 10.1016/j.bmcl.2014.05.084
BindingDB Entry DOI: 10.7270/Q23R0VH6
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50046107
PNG
(CHEMBL3310860)
Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)NNc1ccc(Br)c(C)c1
Show InChI InChI=1S/C15H16BrN3O3S/c1-10-9-13(5-8-15(10)16)18-19-23(21,22)14-6-3-12(4-7-14)17-11(2)20/h3-9,18-19H,1-2H3,(H,17,20)
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n/an/an/an/a 130n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of IDO in human HeLa cells after 24 hrs by spectrophotometry


Bioorg Med Chem Lett 24: 3403-6 (2014)


Article DOI: 10.1016/j.bmcl.2014.05.084
BindingDB Entry DOI: 10.7270/Q23R0VH6
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50046150
PNG
(CHEMBL3310976)
Show SMILES Brc1ccc(NNS(=O)(=O)c2ccc(cc2)C#N)cc1
Show InChI InChI=1S/C13H10BrN3O2S/c14-11-3-5-12(6-4-11)16-17-20(18,19)13-7-1-10(9-15)2-8-13/h1-8,16-17H
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n/an/an/an/a 134n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of IDO in human HeLa cells after 24 hrs by spectrophotometry


Bioorg Med Chem Lett 24: 3403-6 (2014)


Article DOI: 10.1016/j.bmcl.2014.05.084
BindingDB Entry DOI: 10.7270/Q23R0VH6
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50145166
PNG
(CHEMBL3763493)
Show SMILES Cn1c2ccc(cc2n(C)c1=O)S(=O)(=O)NNc1ccc(Br)cc1
Show InChI InChI=1S/C15H15BrN4O3S/c1-19-13-8-7-12(9-14(13)20(2)15(19)21)24(22,23)18-17-11-5-3-10(16)4-6-11/h3-9,17-18H,1-2H3
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n/an/an/an/a 135n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of Indoleamine 2,3-dioxygenase in human HeLa cells in presence of L-tryptophan as substrate after 24 hrs in presence of L-tryptophan


J Med Chem 59: 419-30 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01640
BindingDB Entry DOI: 10.7270/Q2FF3V69
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50203248
PNG
(CHEMBL3930308)
Show SMILES Cc1n[nH]c2Oc3[nH]nc(C)c3C(c12)c1ccc(F)cc1
Show InChI InChI=1S/C15H13FN4O/c1-7-11-13(9-3-5-10(16)6-4-9)12-8(2)18-20-15(12)21-14(11)19-17-7/h3-6,13H,1-2H3,(H,17,19)(H,18,20)
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n/an/an/an/a 135n/an/an/an/a



Indian Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...


ACS Med Chem Lett 7: 1167-1172 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00359
BindingDB Entry DOI: 10.7270/Q2TF009K
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50203263
PNG
(CHEMBL3927265)
Show SMILES Nc1n[nH]c2Oc3[nH]nc(N)c3C(c12)c1ccc(F)c(Cl)c1
Show InChI InChI=1S/C13H10ClFN6O/c14-5-3-4(1-2-6(5)15)7-8-10(16)18-20-12(8)22-13-9(7)11(17)19-21-13/h1-3,7H,(H3,16,18,20)(H3,17,19,21)
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n/an/an/an/a 139n/an/an/an/a



Indian Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...


ACS Med Chem Lett 7: 1167-1172 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00359
BindingDB Entry DOI: 10.7270/Q2TF009K
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50046152
PNG
(CHEMBL3310853)
Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)NNc1ccc(Cl)cc1
Show InChI InChI=1S/C14H14ClN3O3S/c1-10(19)16-12-6-8-14(9-7-12)22(20,21)18-17-13-4-2-11(15)3-5-13/h2-9,17-18H,1H3,(H,16,19)
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n/an/an/an/a 142n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of IDO in human HeLa cells after 24 hrs by spectrophotometry


Bioorg Med Chem Lett 24: 3403-6 (2014)


Article DOI: 10.1016/j.bmcl.2014.05.084
BindingDB Entry DOI: 10.7270/Q23R0VH6
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM168320
PNG
(US9675571, 6)
Show SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1ccc(Cl)c(Cl)c1)[C@H]1C[C@H]1C(O)=O
Show InChI InChI=1S/C25H31Cl2N3O3/c1-14(2)12-30(13-15(3)4)23-8-5-16(18-11-19(18)24(31)32)9-22(23)29-25(33)28-17-6-7-20(26)21(27)10-17/h5-10,14-15,18-19H,11-13H2,1-4H3,(H,31,32)(H2,28,29,33)/t18-,19-/m1/s1
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US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...


US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50046146
PNG
(CHEMBL3310980)
Show SMILES OC(=O)COc1ccc(cc1)S(=O)(=O)NNc1ccc(Br)cc1
Show InChI InChI=1S/C14H13BrN2O5S/c15-10-1-3-11(4-2-10)16-17-23(20,21)13-7-5-12(6-8-13)22-9-14(18)19/h1-8,16-17H,9H2,(H,18,19)
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n/an/an/an/a 152n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of IDO in human HeLa cells after 24 hrs by spectrophotometry


Bioorg Med Chem Lett 24: 3403-6 (2014)


Article DOI: 10.1016/j.bmcl.2014.05.084
BindingDB Entry DOI: 10.7270/Q23R0VH6
More data for this
Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50046110
PNG
(CHEMBL3310981)
Show SMILES OC(=O)c1ccc(cc1)S(=O)(=O)NNc1ccc(Br)cc1
Show InChI InChI=1S/C13H11BrN2O4S/c14-10-3-5-11(6-4-10)15-16-21(19,20)12-7-1-9(2-8-12)13(17)18/h1-8,15-16H,(H,17,18)
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n/an/an/an/a 172n/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of IDO in human HeLa cells after 24 hrs by spectrophotometry


Bioorg Med Chem Lett 24: 3403-6 (2014)


Article DOI: 10.1016/j.bmcl.2014.05.084
BindingDB Entry DOI: 10.7270/Q23R0VH6
More data for this
Ligand-Target Pair
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