Compile Data Set for Download or QSAR
maximum 50k data
Found 20 of kd for UniProtKB: P35354
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM22319((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)
Affinity DataKd:  8.07E+3nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM50514417(CHEMBL4540374)
Affinity DataKd:  10nMAssay Description:Binding affinity to human COX2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM222289(4-(Benzo[d][1,3]dioxol-5-yl)-2-(2-pyrrolidin-1-yl-...)
Affinity DataKd:  51.3nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM222290(4-(Benzo[d][1,3]dioxol-5-yl)-2-(2-morpholin-4-yl-2...)
Affinity DataKd:  203nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM222291(4-(Benzo[d][1,3]dioxol-5-yl)-2-(2-piperidin-1-yl-2...)
Affinity DataKd:  51.1nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM222292(4-(Benzo[d][1,3]dioxol-5-yl)-2-(2-(3-methylpiperid...)
Affinity DataKd:  40.8nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM222293(4-(Benzo[d][1,3]dioxol-5-yl)-2-(2-(3,4-dimethoxyph...)
Affinity DataKd:  14.0nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM222294(4-(Benzo[d][1,3]dioxol-5-yl)-2-(2-(4-methylpiperaz...)
Affinity DataKd:  56.4nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM222295(4-(Benzo[d][1,3]dioxol-5-yl)-2-(2-(4-phenylpiperaz...)
Affinity DataKd:  3.30nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM222296(4-(Benzo[d][1,3]dioxol-5-yl)-2-(2-(4-(4-fluorophen...)
Affinity DataKd:  3.30nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataKd:  1.02E+3nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataKd:  789nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM50366159(CHEMBL1957450)
Affinity DataKd:  0.190nMAssay Description:Binding affinity to COX2 by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM50427217(CHEMBL2324850)
Affinity DataKd:  652nMAssay Description:Binding affinity to COX2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM50486823(CHEMBL2235866)
Affinity DataKd:  448nMAssay Description:Binding affinity to COX2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM50486824(CHEMBL2235864)
Affinity DataKd:  227nMAssay Description:Binding affinity to COX2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataKd:  92nMAssay Description:Binding affinity to COX2 (unknown origin)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM50486825(CHEMBL2235865)
Affinity DataKd:  50nMAssay Description:Binding affinity to COX2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM50486822(CHEBI:76249 | Miroprofen)
Affinity DataKd:  48nMAssay Description:Binding affinity to COX2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Panjab University

LigandPNGBDBM222288(2-(Methoxycarbonylmethyl)-4-(benzo[d][1,3]dioxol-5...)
Affinity DataKd:  230nMAssay Description:Inhibitory activity of the synthesized compounds on COX-1 and COX-2 enzymes were evaluated at 40 μm using the COX Inhibitor Screening Assay Kit ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed